Application | Comment | Organism |
---|---|---|
medicine | hematopoitic prostaglandin synthase controls an inhibitory effect on intestinal tumours | Mus musculus |
medicine | hematopoitic prostaglandin synthase controls an inhibitory effect on intestinal tumours | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | disruption of gene for hematopoietic prostaglandin synthase in ApcMin/+ mice bearing a defect in the adenomatous polyposis coli gene which leads to development of many adenomas leads to 50% more intestinal adenomas compared with controls. Tumour size is not affected | Mus musculus |
additional information | transgenic expression of hematopoitic prostaglandin synthase in ApcMin/+ mice have 80% fewer intestinal adenomas | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
recombinant enzyme | - |
Mus musculus | - |
ApcMin/+ mice bearing a defect in the adenomatous polyposis coli gene which leads to development of many adenomas | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
gut mucosa | - |
Mus musculus | - |
macrophage | of gut mucosa | Mus musculus | - |
monocyte | of gut mucosa | Mus musculus | - |