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Literature summary for 4.2.1.1 extracted from

  • Wetzel, P.; Gros, G.
    Inhibition and kinetic properties of membrane-bound carbonic anhydrases in rabbit skeletal muscles (1998), Arch. Biochem. Biophys., 356, 151-158.
    View publication on PubMed
Search for more literature for 4.2.1.1

Inhibitors

Inhibitors Comment Organism Structure
acetazolamide
-
 Oryctolagus cuniculus
benzolamide
-
 Oryctolagus cuniculus
chlorzolamide
-
 Oryctolagus cuniculus
ethoxyzolamide
-
 Oryctolagus cuniculus
methazolamide
-
 Oryctolagus cuniculus
OCN-
-
 Oryctolagus cuniculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.6
-
 CO2 enzyme from white muscle sarcoplasmic reticulum Oryctolagus cuniculus
2.4
-
 CO2
-
 Oryctolagus cuniculus
3.6
-
 CO2 enzyme from red muscle sarcolemmal membranes Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
sarcolemma associated with Oryctolagus cuniculus 42383
-
sarcoplasmic reticulum associated with Oryctolagus cuniculus 16529
-

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle skeletal muscle Oryctolagus cuniculus
-
muscle white muscle and red muscle Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO2 + H2O
-
 Oryctolagus cuniculus H2CO3
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3830
-
 CO2 enzyme from red muscle sarcoplasmic reticulum Oryctolagus cuniculus
4170
-
 CO2 enzyme from red muscle sarcolemmal membranes Oryctolagus cuniculus
6170
-
 CO2 enzyme from white muscle sarcoplasmic reticulum Oryctolagus cuniculus
9000
-
 CO2 enzyme from white muscle sarcolemmal membranes Oryctolagus cuniculus