Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cd2+ | 1 mM | Rattus norvegicus | |
Co2+ | 1 mM | Rattus norvegicus | |
diisopropyl fluorophosphate | - |
Rattus norvegicus | |
Diprotin A | - |
Rattus norvegicus | |
Hg2+ | 1 mM | Rattus norvegicus | |
Ni2+ | 1 mM | Rattus norvegicus | |
phenylmethylsulfonyl fluoride | slight | Rattus norvegicus | |
Zn2+ | 1 mM | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.025 | - |
Tyr-Pro-Phe-Val-Glu-Pro-Ile | - |
Rattus norvegicus | |
0.05 | - |
Arg-Pro-Lys-Pro | - |
Rattus norvegicus | |
0.05 | - |
Tyr-Pro-Phe-Val-Glu-Pro-Ile | - |
Rattus norvegicus | |
0.05 | - |
Tyr-Pro-Phe-Pro-Gly | - |
Rattus norvegicus | |
0.05 | - |
Tyr-Pro-Phe | - |
Rattus norvegicus | |
0.05 | - |
Tyr-Pro-Phe-Pro | - |
Rattus norvegicus | |
0.09 | - |
Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 | - |
Rattus norvegicus | |
0.15 | - |
Arg-Pro-Lys-Pro-Gln-Gln-Phe | - |
Rattus norvegicus | |
0.18 | - |
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly | - |
Rattus norvegicus | |
0.3 | - |
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 | - |
Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
90000 | - |
2 * 90000, SDS-PAGE | Rattus norvegicus |
190000 | - |
gel filtration | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | glycoprotein | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epidermis | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
31.9 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Arg-Pro-Lys-Pro + H2O | - |
Rattus norvegicus | ? | - |
? | |
Arg-Pro-Lys-Pro-Gln-Gln-Phe + H2O | - |
Rattus norvegicus | ? | - |
? | |
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly | - |
Rattus norvegicus | Arg-Pro + Lys-Pro-Gln-Gln-Phe-Phe-Gly | - |
? | |
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly + H2O | - |
Rattus norvegicus | ? | - |
? | |
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 + H2O | - |
Rattus norvegicus | Arg-Pro + Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 | - |
? | |
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH3 + H2O | - |
Rattus norvegicus | ? | - |
? | |
beta-casomorphin + H2O | beta-casomorphin from human, i.e. Tyr-Pro-Phe-Val-Glu-Pro-Ileu | Rattus norvegicus | ? | - |
? | |
beta-casomorphin + H2O | beta-casomorphin from bovine, i.e. Tyr-Pro-Phe-Val-Glu-Pro-Ile | Rattus norvegicus | ? | - |
? | |
Gly-Pro-4-nitroanilide + H2O | - |
Rattus norvegicus | Gly-Pro + 4-nitroaniline | - |
? | |
Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 + H2O | - |
Rattus norvegicus | ? | - |
? | |
substance P + H2O | - |
Rattus norvegicus | Arg-Pro + Lys-Pro + ? | - |
? | |
Tyr-Pro-Phe + H2O | - |
Rattus norvegicus | ? | - |
? | |
Tyr-Pro-Phe-Pro + H2O | - |
Rattus norvegicus | ? | - |
? | |
Tyr-Pro-Phe-Pro-Gly + H2O | - |
Rattus norvegicus | ? | - |
? | |
Tyr-Pro-Phe-Val-Glu-Pro-Ile + H2O | - |
Rattus norvegicus | Tyr-Pro + Phe-Val-Glu-Pro-Ile | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 90000, SDS-PAGE | Rattus norvegicus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
pH 6.0-9.5, stable for 2 h | Rattus norvegicus |
45 | - |
10 min, stable | Rattus norvegicus |
60 | - |
10 min, 46% loss of activity | Rattus norvegicus |
70 | - |
10 min, complete loss of activity | Rattus norvegicus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
50.3 | - |
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 | - |
Rattus norvegicus | |
60.3 | - |
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly | - |
Rattus norvegicus | |
62.3 | - |
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Gly | - |
Rattus norvegicus | |
66.1 | - |
Arg-Pro-Lys-Pro | - |
Rattus norvegicus | |
71.4 | - |
Tyr-Pro-Phe-Val-Glu-Pro-Ile | - |
Rattus norvegicus | |
87.5 | - |
Tyr-Pro-Phe | - |
Rattus norvegicus | |
88.3 | - |
Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 | - |
Rattus norvegicus | |
90.8 | - |
Tyr-Pro-Phe-Pro | - |
Rattus norvegicus | |
102 | - |
Tyr-Pro-Phe-Pro-Gly | - |
Rattus norvegicus | |
103 | - |
Tyr-Pro-Phe-Val-Glu-Pro-Ileu | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
hydrolysis of Gly-Pro-4-nitroanilide, substance P or beta-casomorphin | Rattus norvegicus |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
6 | 9.5 | at 37°C stable for 2 h, at 4°C stable for 3 days | Rattus norvegicus |