Inhibitors | Comment | Organism | Structure |
---|---|---|---|
calyculin | moderate inhibition at 0.00001 mM | Homo sapiens | |
cantheridin | strong inhibition at 0.005 mM | Homo sapiens | |
EGTA | moderate inhibition | Homo sapiens | |
NaF | moderate inhibition; strong inhibition | Homo sapiens | |
Tartrate | moderate inhibition of P11 at 2 mM; strong inhibition | Homo sapiens | |
tetramisole | strong inhibition at 2 mM | Homo sapiens | |
Trifluorperazine | moderate inhibition; strong inhibition; strong inhibition at 0.1 mM | Homo sapiens | |
vanadate | at 1 mM inhibition to 60% of its activity | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Homo sapiens | |
Co2+ | - |
Homo sapiens | |
Mg2+ | - |
Homo sapiens | |
Mg2+ | better activator than Mn2+ | Homo sapiens | |
Mn2+ | - |
Homo sapiens | |
Mn2+ | better activator than Mg2+ | Homo sapiens | |
Ni2+ | - |
Homo sapiens | |
Ni2+ | best activator | Homo sapiens | |
Ni2+ | best activator for P5 | Homo sapiens | |
Zn2+ | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
gel filtration | Homo sapiens |
49000 | - |
gel filtration | Homo sapiens |
90000 | - |
gel filtration | Homo sapiens |
150000 | - |
gel filtration | Homo sapiens |
165000 | - |
gel filtration | Homo sapiens |
250000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.5 | - |
with phosphorylase kinase as substrate | Homo sapiens |
2 | - |
with phosphorylase kinase as substrate | Homo sapiens |
3 | - |
with phosphorylase kinase as substrate | Homo sapiens |
3 | 8 | with p-nitrophenylphosphate as substrate | Homo sapiens |
4 | - |
with phosphorylase kinase as substrate | Homo sapiens |
8 | - |
with phosphorylase kinase as substrate | Homo sapiens |
11 | - |
with p-nitrophenyl phosphate as substrate | Homo sapiens |
14 | - |
with p-nitrophenyl phosphate as substrate | Homo sapiens |
16 | - |
with p-nitrophenyl phosphate as substrate | Homo sapiens |
19 | - |
with p-nitrophenyl phosphate as substrate | Homo sapiens |
40 | - |
with p-nitrophenyl phosphate as substrate | Homo sapiens |
310 | - |
with p-nitrophenyl phosphate as substrate | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
p-nitrophenyl phosphate + H2O | - |
Homo sapiens | p-nitrophenol + phosphate | - |
? | |
phosphorylated AD P-Tau + H2O | - |
Homo sapiens | AD P-Tau + phosphate | - |
? | |
phosphorylated phosphorylase kinase + H2O | - |
Homo sapiens | phosphorylase kinase + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
P10 | - |
Homo sapiens |
P11 | - |
Homo sapiens |
P5 | - |
Homo sapiens |
P6 | - |
Homo sapiens |
P7 | - |
Homo sapiens |
P8 | - |
Homo sapiens |
P9 | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
biphasic pH-optimum at pH 7.5 and 8.5 with Mn2+ as activator | Homo sapiens |
7 | - |
with Mg2+ as activator | Homo sapiens |
7.5 | - |
with Mn2+ as activator | Homo sapiens |
7.5 | 8.5 | with Mn2+ as activator | Homo sapiens |
7.5 | 8 | with Mg2+ as activator | Homo sapiens |
8.5 | - |
with Mg2+ as activator | Homo sapiens |
8.5 | - |
with Mn2+ as activator | Homo sapiens |
10 | - |
with Mg2+ as activator | Homo sapiens |