Inhibitors | Comment | Organism | Structure |
---|---|---|---|
FTRKRQRAMRRVHQ | autoregulatory pseudosubstrate sequence, residues 24-40, lung enzyme | Homo sapiens | |
additional information | synthesis of peptides behaving as pseudosubstrates, determination of inhibitory potential | Drosophila melanogaster | |
additional information | synthesis of peptides behaving as pseudosubstrates, determination of inhibitory potential, sequences of the different enzyme forms, required sequence properties, overview | eukaryota | |
additional information | synthesis of peptides behaving as pseudosubstrates, determination of inhibitory potential | Homo sapiens | |
additional information | synthesis of peptides behaving as pseudosubstrates, determination of inhibitory potential | Saccharomyces cerevisiae | |
NKMKSRLRKGALKKNV | autoregulatory pseudosubstrate sequence, residues 24-40 | Drosophila melanogaster | |
QLMGGLHRHGAIINRKE | autoregulatory pseudosubstrate sequence, residues 391-407 | Saccharomyces cerevisiae | |
Tween 80 | inhibits the enzyme at high concentration | Drosophila melanogaster | |
Tween 80 | inhibits the enzyme at high concentration | eukaryota | |
Tween 80 | inhibits the enzyme at high concentration | Homo sapiens | |
Tween 80 | inhibits the enzyme at high concentration | Saccharomyces cerevisiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Drosophila melanogaster | |
Mg2+ | - |
eukaryota | |
Mg2+ | - |
Homo sapiens | |
Mg2+ | - |
Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | Drosophila melanogaster | - |
ADP + a phosphoprotein | - |
? | |
ATP + a protein | eukaryota | - |
ADP + a phosphoprotein | - |
? | |
ATP + a protein | Homo sapiens | - |
ADP + a phosphoprotein | - |
? | |
ATP + a protein | Saccharomyces cerevisiae | - |
ADP + a phosphoprotein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
eukaryota | - |
enzyme forms alpha, betaI ans betaII, gamma, epsilon, delta, zeta | - |
Homo sapiens | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | - |
Drosophila melanogaster | ADP + a phosphoprotein | - |
? | |
ATP + a protein | - |
eukaryota | ADP + a phosphoprotein | - |
? | |
ATP + a protein | - |
Homo sapiens | ADP + a phosphoprotein | - |
? | |
ATP + a protein | - |
Saccharomyces cerevisiae | ADP + a phosphoprotein | - |
? | |
additional information | substrate specificity | Drosophila melanogaster | ? | - |
? | |
additional information | substrate specificity | eukaryota | ? | - |
? | |
additional information | substrate specificity | Homo sapiens | ? | - |
? | |
additional information | substrate specificity | Saccharomyces cerevisiae | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKC | - |
Drosophila melanogaster |
PKC | - |
eukaryota |
PKC | - |
Homo sapiens |
PKC | - |
Saccharomyces cerevisiae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Drosophila melanogaster | |
ATP | - |
eukaryota | |
ATP | - |
Homo sapiens | |
ATP | - |
Saccharomyces cerevisiae |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Ki values of the pseudosubstrates in nano- to micromolar range | Drosophila melanogaster | |
additional information | - |
additional information | Ki values of the pseudosubstrates in nano- to micromolar range | eukaryota | |
additional information | - |
additional information | Ki values of the pseudosubstrates in nano- to micromolar range | Homo sapiens | |
additional information | - |
additional information | Ki values of the pseudosubstrates in nano- to micromolar range | Saccharomyces cerevisiae |