Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cAMP | dependent on, structural basis of activation mechanism, binding induces conformational changes in the regulatory subunit RIalpha | Mus musculus |
Crystallization (Comment) | Organism |
---|---|
complex between the catalytic subunit and a deletion mutant regulatory subunit RIalpha comprising residues 91-244, structure determination and analysis | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
IP20 | peptide RRNAI, derived from the inhibitory sequence of RIalpha comprising residues 94-98, inhibition mechanism | Mus musculus | |
additional information | molecular mechanism of enzyme inhibition by binding of catalytic and regulatory subunits via extended surface of subunit C, overview | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Subunits | Comment | Organism |
---|---|---|
More | structure of subunit C, subunit R, the cAMP binding site, and the activation loop, interaction sites, overview | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
PKA | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |