Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | treatment of rats with 2-(4-chlorophenoxy)-2-methylpropionic acid, i.e. clofibric acid, or feeding of a fat-free diet markedly elevated hepatic activity of SCD by increasing the steady-state level of SCD1 mRNA and enhancing transcriptional rate, metabolic effects, overview | Rattus norvegicus |
Cloned (Comment) | Organism |
---|---|
SCD1, realtime-PCR-based quantitative expression analysis | Rattus norvegicus |
SCD2, realtime-PCR-based quantitative expression analysis | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | decreased degradation of SCD is responsible for the increase in palmitoyl-CoA chain elongase activity in addition to increased transcription of SCD1 in the rats treated with clofibric acid, overview | ? | - |
? | |
stearoyl-CoA + ferrocytochrome b5 + O2 + H+ | Rattus norvegicus | - |
oleoyl-CoA + ferricytochrome b5 + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P07308 | SCD1 | - |
Rattus norvegicus | Q6P7B9 | SCD2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | decreased degradation of SCD is responsible for the increase in palmitoyl-CoA chain elongase activity in addition to increased transcription of SCD1 in the rats treated with clofibric acid, overview | Rattus norvegicus | ? | - |
? | |
stearoyl-CoA + ferrocytochrome b5 + O2 + H+ | - |
Rattus norvegicus | oleoyl-CoA + ferricytochrome b5 + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SCD | - |
Rattus norvegicus |
SCD2 | - |
Rattus norvegicus |
stearoyl-CoA desaturase | - |
Rattus norvegicus |
stearoyl-CoA desaturase 2 | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ferrocytochrome b5 | - |
Rattus norvegicus |