KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics with lysophospholipid substrates | Sus scrofa | |
0.0151 | - |
1-linoleoyl lysophosphatidylcholine | pH 7.5, 25°C | Sus scrofa | |
0.0312 | - |
linoleic acid | pH 7.5, 25°C | Sus scrofa | |
0.0355 | - |
1-linoleoyl lysophosphatidic acid | pH 7.5, 25°C | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonate + O2 | Sus scrofa | - |
(5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyeicosa-5,8,10,14-tetraenoate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Sus scrofa | - |
leukocyte | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
51.8 | - |
commercial preparation | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-linoleoyl lysophosphatidic acid + O2 | i.e. linoleoyl-lysoPA | Sus scrofa | (S)-hydroperoxy 1-linoleoyl lysophosphatidic acid | major product | ? | |
1-linoleoyl lysophosphatidylcholine + O2 | i.e. linoleoyl-lysoPC | Sus scrofa | (S)-hydroperoxy 1-linoleoyl lysophosphatidylcholine | major product | ? | |
arachidonate + O2 | - |
Sus scrofa | (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyeicosa-5,8,10,14-tetraenoate | - |
? | |
linoleic acid + O2 | - |
Sus scrofa | (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate | - |
? | |
additional information | stereo-selectivity in LOX-catalyzed oxygenation of lysophospholipids, overview | Sus scrofa | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
12-lipoxygenase | - |
Sus scrofa |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Sus scrofa |