Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | addition of non-toxic concentrations of H2O2 to cultured THP-1 cells neither influences catalase activity nor mRNA expression levels and activity of cathepsins | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-Amino-1,2,4-triazole | inhibitory. Inhibition of extracellular catalase activity leads to a striking inactivation of secreted cysteine cathepsins | Homo sapiens | |
KCN | inhibitory. Inhibition of extracellular catalase activity leads to a striking inactivation of secreted cysteine cathepsins | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | constitutive, basal level of catalase activity. Inhibition of extracellular catalase activity by 3-amino-1,2,4-triazole or KCN leads to a striking inactivation of secreted cysteine cathepsins | Homo sapiens | - |
- |
peroxisome | main localization | Homo sapiens | 5777 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
THP-1 cell | - |
Homo sapiens | - |