Reference on EC 4.1.1.71 - 2-oxoglutarate decarboxylase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Faff-Michalak, L.; Albrecht, J.
The two catalytic components of the 2-oxoglutarate dehydrogenase complex in rat cerebral synaptic and nonsynaptic mitochondria: Comparison of the response to in vitro treatment with ammonia, hyperammonemia, and hepatic encephalopathy
Neurochem. Res.
18
119-123
1993
BRENDA: Rattus norvegicus
Textmining: Rattus
Palaniappan, C.; Sharma, V.; Hudspeth, M.E.; Meganathan, R.
Menaquinone (vitamin K2) biosynthesis: evidence that the Escherichia coli menD gene encodes both 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase and alpha-ketoglutarate decarboxylase activities
J. Bacteriol.
174
8111-8118
1992
Escherichia coli
Shigeoka, S.; Onishi, T.; Maeda, K.; Nakano, Y.; Kitaoka, S.
Occurence of thiamin pyrophopshate-dependent 2-oxoglutarate decarboxylase in mitochondria of Euglena gracilis
FEBS Lett.
195
43-47
1986
Euglena gracilis
-
Shigeoka, S.; Nakano, Y.
Characterization and molecular properties of 2-oxoglutarate decarboxylase from Euglena gracilis
Arch. Biochem. Biophys.
288
22-28
1991
BRENDA: Euglena gracilis
Textmining: Euglena, Saccharomyces cerevisiae, Oryctolagus cuniculus
Kapol, R.; Radler, F.
Purification and characterization of 2-oxoglutarate decarboxylase of Leuconostoc mesenteroides
J. Gen. Microbiol.
136
1497-1499
1990
Oenococcus oeni, Oenococcus oeni B 211
-
Shigeoka, S.; Hanaoka, T.; Kishi, N.; Nakano, Y.
Effect of L-glutamate on 2-oxoglutarate decarboxylase in Euglena gracilis
Biochem. J.
282
319-323
1992
Euglena gracilis, Euglena gracilis SM-ZK
-
Shigeoka, S.; Nakano, Y.
The effect of thiamin on the activation of thiamin pyrophosphate-dependent 2-oxoglutarate decarboxylase in Euglena gracilis
Biochem. J.
292
463-467
1993
Euglena gracilis
-
Bhasin, M.; Billinsky, J.L.; palmer, D.R.J.
Steady-state kinetics and molecular evolution of Escherichia coli MenD [(1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase], an anomalous thiamin diphosphate-dependent decarboxylase-carboligase
Biochemistry
42
13496-13504
2003
Escherichia coli, Bacteria, Halobacterium sp., Arabidopsis thaliana, archaeon
Tian, J.; Bryk, R.; Itoh, M.; Suematsu, M.; Nathan, C.
Variant tricarboxylic acid cycle in Mycobacterium tuberculosis: identification of alpha-ketoglutarate decarboxylase
Proc. Natl. Acad. Sci. USA
102
10670-10675
2005
BRENDA: Mycobacterium tuberculosis
Textmining: Homo sapiens
Jones, D.D.; Perham, R.N.
The role of loop and beta-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex
Biochem. J.
409
357-366
2008
Escherichia coli, insertion sequences
de Carvalho, L.P.; Zhao, H.; Dickinson, C.E.; Arango, N.M.; Lima, C.D.; Fischer, S.M.; Ouerfelli, O.; Nathan, C.; Rhee, K.Y.
Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase
Chem. Biol.
17
323-332
2010
Mycobacterium tuberculosis (P9WIS5), Mycobacterium tuberculosis
Bjornstad, L.G.; Zoppellaro, G.; Tomter, A.B.; Falnes, P.O.; Andersson, K.K.
Spectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4
Biochem. J.
434
391-398
2011
Homo sapiens
Yuan, Z.; Yin, B.; Wei, D.; Yuan, Y.R.
Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J. Struct. Biol.
182
125-135
2013
Synechococcus elongatus PCC 6301
Wagner, T.; Barilone, N.; Alzari, P.M.; Bellinzoni, M.
A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (alpha-ketoglutarate decarboxylase)
Biochem. J.
457
425-434
2014
Mycolicibacterium smegmatis (A0R3B1)
Wagner, T.; Bellinzoni, M.; Wehenkel, A.; OHare, H.M.; Alzari, P.M.
Functional plasticity and allosteric regulation of alpha-ketoglutarate decarboxylase in central mycobacterial metabolism
Chem. Biol.
18
1011-1020
2011
Mycobacterium tuberculosis, Mycolicibacterium smegmatis (A0R2B1), Mycolicibacterium smegmatis mc(2)155 / ATCC 700084 (A0R2B1), Mycobacterium tuberculosis H37Rv
Yuan, Z.; Yin, B.; Wei, D.; Yuan, Y.R.
Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase
J. Struct. Biol.
182
125-135
2013
Synechococcus elongatus PCC 6301
Sykes, S.; Szempruch, A.; Hajduk, S.
The Krebs cycle enzyme alpha-ketoglutarate decarboxylase is an essential glycosomal protein in bloodstream African trypanosomes
Eukaryot. Cell
14
206-215
2015
Trypanosoma brucei
Lei, G.; Wang, X.; Lai, C.; Li, Z.M.; Zhang, W.; Xie, C.; Wang, F.; Wu, X.; Li, Z.
Expression and biochemical characterization of alpha-ketoglutarate decarboxylase from cyanobacterium Synechococcus sp. PCC7002
Int. J. Biol. Macromol.
114
188-193
2018
Synechococcus sp. PCC 7002
Zhang, S.; Qian, X.; Chang, S.; Dismukes, G.C.; Bryant, D.A.
Natural and synthetic variants of the tricarboxylic acid cycle in cyanobacteria introduction of the GABA shunt into Synechococcus sp. PCC 7002
Front. Microbiol.
7
1972
2016
Cyanobacteria
Jones, D.D.; Stott, K.M.; Reche, P.A.; Perham, R.N.
Recognition of the lipoyl domain is the ultimate determinant of substrate channelling in the pyruvate dehydrogenase multienzyme complex
J. Mol. Biol.
305
49-60
2001
Escherichia coli (P06959), Escherichia coli
Pawełczyk, T; Angielski, S
Cooperation of Ca2+ and pH in regulation of the activity of the 2-oxoglutarate dehydrogenase complex and its components from bovine kidney cortex.
Acta Biochim Pol
31
289-305
1984
Electron
Danpure, CJ; Purkiss, P; Jennings, PR; Watts, RW
Mitochondrial damage and the subcellular distribution of 2-oxoglutarate:glyoxylate carboligase in normal human and rat liver and in the liver of a patient with primary hyperoxaluria type I.
Clin Sci (Lond)
70
417-25
1986
Rattus
Snechkute, MA; Glemzha, AA
[Catalytic properties of alpha-ketoglutarate decarboxylase from bovine brain]
Biokhimiia
41
491-5
1976
Bos taurus
Shigeoka, S; Hanaoka, T; Kishi, N; Nakano, Y
Effect of L-glutamate on 2-oxoglutarate decarboxylase in Euglena gracilis.
Biochem J
282 ( Pt 2)
319-23
1992
Euglena gracilis, Euglena
Shigeoka, S; Nakano, Y
The effect of thiamin on the activation of thiamin pyrophosphate-dependent 2-oxoglutarate decarboxylase in Euglena gracilis.
Biochem J
292 ( Pt 2)
463-7
1993
Euglena gracilis, Euglena
Bjrnstad, LG; Meza, TJ; Otterlei, M; Olafsrud, SM; Meza-Zepeda, LA; Falnes, P
Human ALKBH4 interacts with proteins associated with transcription.
PLoS One
7
e49045
2012
Homo sapiens, Saccharomyces cerevisiae
Nilsen, A; Fusser, M; Greggains, G; Fedorcsak, P; Klungland, A
ALKBH4 depletion in mice leads to spermatogenic defects.
PLoS One
9
e105113
2014
Mus sp.
Nakazawa, M; Hayashi, R; Takenaka, S; Inui, H; Ishikawa, T; Ueda, M; Sakamoto, T; Nakano, Y; Miyatake, K
Physiological functions of pyruvate:NADP(+) oxidoreductase and 2-oxoglutarate decarboxylase in Euglena gracilis under aerobic and anaerobic conditions.
Biosci Biotechnol Biochem
81
1386-1393
2017
Euglena gracilis, Euglena
Sun, Q; Liu, X; Gong, B; Wu, D; Meng, A; Jia, S
Alkbh4 and Atrn Act Maternally to Regulate Zebrafish Epiboly.
Int J Biol Sci
13
1051-1066
2017
Danio rerio, Saccharomyces cerevisiae
Zhang, S; Bryant, DA
The tricarboxylic acid cycle in cyanobacteria.
Science
334
1551-3
2011
Synechococcus sp., Synechococcus elongatus PCC 6301
Green, LS; Li, Y; Emerich, DW; Bergersen, FJ; Day, DA
Catabolism of alpha-ketoglutarate by a sucA mutant of Bradyrhizobium japonicum: evidence for an alternative tricarboxylic acid cycle.
J Bacteriol
182
2838-44
2000
Bradyrhizobium japonicum, Glycine max
Xiong, W; Brune, D; Vermaas, WF
The ?-aminobutyric acid shunt contributes to closing the tricarboxylic acid cycle in Synechocystis sp. PCC 6803.
Mol Microbiol
93
786-96
2014
Synechocystis sp.
O'Hare, HM; Durán, R; Cerveñansky, C; Bellinzoni, M; Wehenkel, AM; Pritsch, O; Obal, G; Baumgartner, J; Vialaret, J; Johnsson, K; Alzari, PM
Regulation of glutamate metabolism by protein kinases in mycobacteria.
Mol Microbiol
70
1408-23
2008
Corynebacterium glutamicum, Corynebacteriales, Mycobacterium tuberculosis
Li, MM; Nilsen, A; Shi, Y; Fusser, M; Ding, YH; Fu, Y; Liu, B; Niu, Y; Wu, YS; Huang, CM; Olofsson, M; Jin, KX; Lv, Y; Xu, XZ; He, C; Dong, MQ; Rendtlew Danielsen, JM; Klungland, A; Yang, YG
ALKBH4-dependent demethylation of actin regulates actomyosin dynamics.
Nat Commun
4
1832
2013
Mus sp.
Kuroda, Y; Kline, JJ; Sweetman, L; Nyhan, WL; Groshong, TD
Abnormal pyruvate and alpha-ketoglutarate dehydrogenase complexes in a patient with lactic acidemia.
Pediatr Res
13
928-31
1979
Homo sapiens
Surendran, S; Michals-Matalon, K; Krywawych, S; Qazi, QH; Tuchman, R; Rady, PL; Tyring, SK; Matalon, R
DOOR syndrome: deficiency of E1 component of the 2-oxoglutarate dehydrogenase complex.
Am J Med Genet
113
371-4
2002
Homo sapiens
Shen, C; Yan, T; Tong, T; Shi, D; Ren, L; Zhang, Y; Zhang, X; Cao, Y; Yan, Y; Ma, Y; Zhu, X; Tian, X; Fang, JY; Chen, H; Ji, L; Hong, J; Xuan, B
ALKBH4 Functions as a Suppressor of Colorectal Cancer Metastasis via Competitively Binding to WDR5.
Front Cell Dev Biol
8
293
2020
Homo sapiens
Jingushi, K; Aoki, M; Ueda, K; Kogaki, T; Tanimoto, M; Monoe, Y; Ando, M; Matsumoto, T; Minami, K; Ueda, Y; Kitae, K; Hase, H; Nagata, T; Harada-Takeda, A; Yamamoto, M; Kawahara, K; Tabata, K; Furukawa, T; Sato, M; Tsujikawa, K
ALKBH4 promotes tumourigenesis with a poor prognosis in non-small-cell lung cancer.
Sci Rep
11
8677
2021
Homo sapiens
Kweon, SM; Chen, Y; Moon, E; Kvederaviciut?, K; Klimasauskas, S; Feldman, DE
An Adversarial DNA N6-Methyladenine-Sensor Network Preserves Polycomb Silencing.
Mol Cell
74
1138-1147.e6
2019
Bacteria
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