Disease on EC 3.4.23.39 - plasmepsin II
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Breast Neoplasms
Identification of Sulfamoylbenzamide derivatives as selective Cathepsin D inhibitors.
Carcinoma, Hepatocellular
Antimalarial evaluation of copper(II) nanohybrid solids: inhibition of plasmepsin II, a hemoglobin-degrading malarial aspartic protease from Plasmodium falciparum.
Gastroesophageal Reflux
[FEATURES MANIFESTATIONS COMORBID CURRENTS OF GASTROESOPHAGEAL REFLUX DISEASE AND ARTERIAL HYPERTENSION DEPENDING ON THE DEGREE OF ARTERIAL HYPERTENSION].
Infections
Imported malaria and artemisinin-based combination therapy failure in travellers returning to Belgium: A retrospective study.
Malaria
alpha-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases.
Malaria
Antimalarial evaluation of copper(II) nanohybrid solids: inhibition of plasmepsin II, a hemoglobin-degrading malarial aspartic protease from Plasmodium falciparum.
Malaria
Computer-aided design and synthesis of nonpeptidic plasmepsin II and IV inhibitors.
Malaria
Crystal structure of the novel aspartic proteinase zymogen proplasmepsin II from plasmodium falciparum.
Malaria
Efficacy and safety of pyronaridine-artesunate plus single-dose primaquine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Cambodia.
Malaria
Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV.
Malaria
Identification and characterization of allophenylnorstatine-based inhibitors of plasmepsin II, an antimalarial target.
Malaria
Identification of potent inhibitors of Plasmodium falciparum plasmepsin II from an encoded statine combinatorial library.
Malaria
Identification of Sulfamoylbenzamide derivatives as selective Cathepsin D inhibitors.
Malaria
No evidence of amplified Plasmodium falciparum plasmepsin II gene copy number in an area with artemisinin-resistant malaria along the China-Myanmar border.
Malaria
Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterization.
Malaria
Potent inhibitors of the Plasmodium falciparum enzymes plasmepsin I and II devoid of cathepsin D inhibitory activity.
Malaria
Protein surface roughness accounts for binding free energy of Plasmepsin II-ligand complexes.
Malaria
Pyrrolidine derivatives as plasmepsin inhibitors: binding mode analysis assisted by molecular dynamics simulations of a highly flexible protein.
Malaria
Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors.
Malaria
Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum.
Starvation
Identification and characterization of allophenylnorstatine-based inhibitors of plasmepsin II, an antimalarial target.
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