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Disease on EC 3.4.23.39 - plasmepsin II

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Breast Neoplasms
Identification of Sulfamoylbenzamide derivatives as selective Cathepsin D inhibitors.
Carcinoma, Hepatocellular
Antimalarial evaluation of copper(II) nanohybrid solids: inhibition of plasmepsin II, a hemoglobin-degrading malarial aspartic protease from Plasmodium falciparum.
Gastroesophageal Reflux
[FEATURES MANIFESTATIONS COMORBID CURRENTS OF GASTROESOPHAGEAL REFLUX DISEASE AND ARTERIAL HYPERTENSION DEPENDING ON THE DEGREE OF ARTERIAL HYPERTENSION].
Infections
Imported malaria and artemisinin-based combination therapy failure in travellers returning to Belgium: A retrospective study.
Plasmodium falciparum Plasmepsin 2 Duplications, West Africa.
Malaria
Active site specificity of plasmepsin II.
alpha-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases.
Antimalarial evaluation of copper(II) nanohybrid solids: inhibition of plasmepsin II, a hemoglobin-degrading malarial aspartic protease from Plasmodium falciparum.
Computer-aided design and synthesis of nonpeptidic plasmepsin II and IV inhibitors.
Crystal structure of the novel aspartic proteinase zymogen proplasmepsin II from plasmodium falciparum.
Efficacy and safety of pyronaridine-artesunate plus single-dose primaquine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Cambodia.
Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV.
Identification and characterization of allophenylnorstatine-based inhibitors of plasmepsin II, an antimalarial target.
Identification of potent inhibitors of Plasmodium falciparum plasmepsin II from an encoded statine combinatorial library.
Identification of Sulfamoylbenzamide derivatives as selective Cathepsin D inhibitors.
No evidence of amplified Plasmodium falciparum plasmepsin II gene copy number in an area with artemisinin-resistant malaria along the China-Myanmar border.
Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterization.
Potent inhibitors of the Plasmodium falciparum enzymes plasmepsin I and II devoid of cathepsin D inhibitory activity.
Protein surface roughness accounts for binding free energy of Plasmepsin II-ligand complexes.
Pyrrolidine derivatives as plasmepsin inhibitors: binding mode analysis assisted by molecular dynamics simulations of a highly flexible protein.
Screening aspartyl proteases with combinatorial libraries.
Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors.
Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum.
Starvation
Identification and characterization of allophenylnorstatine-based inhibitors of plasmepsin II, an antimalarial target.