Disease on EC 2.4.99.3 - alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase
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(n-acetylneuraminyl)-galactosylglucosylceramide n-acetylgalactosaminyltransferase deficiency
ST3GAL5-Related Disorders: A Deficiency in Ganglioside Metabolism and a Genetic Cause of Intellectual Disability and Choreoathetosis.
Acquired Immunodeficiency Syndrome
[Developments in the serological diagnosis of malignant diseases]
Adenocarcinoma
Alterations of CMP-NeuAc:asialofetuin sialyltransferase activities in human colorectal adenocarcinoma.
Adenocarcinoma
Association of cytosolic sialidase Neu2 with plasma membrane enhances Fas-mediated apoptosis by impairing PI3K-Akt/mTOR-mediated pathway in pancreatic cancer cells.
Adenocarcinoma
Enhancement of metastatic ability by ectopic expression of ST6GalNAcI on a gastric cancer cell line in a mouse model.
Adenocarcinoma
Plasma sialyl transferase total and isoenzyme activity in the diagnosis of cancer of the colon.
Adenocarcinoma
Role of sialyltransferases involved in the biosynthesis of Lewis antigens in human pancreatic tumour cells.
Adenocarcinoma
ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage.
alpha 1-Antitrypsin Deficiency
The serum sialyltransferase activity in alpha 1-antitrypsin deficiency.
alpha-n-acetylgalactosaminide alpha-2,6-sialyltransferase deficiency
Cytidine-5'-monophosphate-N-acetylneuraminic acid. Asialoglycoprotein sialic acid transferase activity in liver and serum of patients with juvenile hepatic cirrhosis and alpha-1-antitrypsin deficiency.
alpha-n-acetylgalactosaminide alpha-2,6-sialyltransferase deficiency
Demonstration of sialyltransferase deficiency in the serum of a patient with alpha-1-antitrypsin deficiency and hepatic cirrhosis.
alpha-n-acetylgalactosaminide alpha-2,6-sialyltransferase deficiency
Genetically altered mice with different sialyltransferase deficiencies show tissue-specific alterations in sialylation and sialic acid 9-O-acetylation.
alpha-n-acetylgalactosaminide alpha-2,6-sialyltransferase deficiency
Letter:serum sialyltransferase deficiency in alpha-1-antitrypsin deficiency.
alpha-n-acetylgalactosaminide alpha-2,6-sialyltransferase deficiency
ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling.
alpha-n-acetylgalactosaminide alpha-2,6-sialyltransferase deficiency
The serum sialyltransferase activity in alpha 1-antitrypsin deficiency.
Alzheimer Disease
The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.
Arthritis, Rheumatoid
Sialyltransferase and Neuraminidase Levels/Ratios and Sialic Acid Levels in Peripheral Blood B Cells Correlate with Measures of Disease Activity in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Pilot Study.
Astrocytoma
Sialyltransferase levels and ganglioside expression in melanoma and other cultured human cancer cells.
Atherosclerosis
Plasma sialyltransferase activity in healthy subjects and atherosclerotic patients.
Atherosclerosis
Sialyltransferase activity of human plasma and aortic intima is enhanced in atherosclerosis.
Atherosclerosis
ST6GAL1 negatively regulates monocyte transendothelial migration and atherosclerosis development.
Autoimmune Diseases
ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling.
Bacteremia
Enhanced bacteremia in human factor H transgenic rats infected by Neisseria meningitidis.
Bernard-Soulier Syndrome
Glycoprotein-sialyltransferase activity of normal human, thrombasthenic and Bernard-Soulier platelets.
beta-d-galactosyl-(1->3)-n-acetyl-beta-d-galactosaminide alpha-2,3-sialyltransferase deficiency
Genetically altered mice with different sialyltransferase deficiencies show tissue-specific alterations in sialylation and sialic acid 9-O-acetylation.
beta-galactoside alpha-(2,6)-sialyltransferase deficiency
Sweet role of platelet endothelial cell adhesion molecule in understanding angiogenesis.
Blast Crisis
Sialyltransferase activity as a marker for the differentiation of lymphocytes. Increase in sialyltransferase activity of blasts from acute lymphoblastic leukaemia cases by 12-o-tetradecanoylphorbol-13-acetate (TPA).
Brachial Plexus Neuritis
Mutation analysis of a putative sialyltransferase gene, the SFRS2 splicing factor gene and the c-myb ET-locus in two families with hereditary neuralgic amyotrophy (HNA).
Brain Neoplasms
Alterations in serum sialyltransferase activities in patients with brain tumors.
Brain Neoplasms
The expression of CMP-NeuAc: Gal beta 1,4GlcNAc alpha 2,6 sialyltransferase [EC 2.4.99.1] and glycoproteins bearing alpha 2,6-linked sialic acids in human brain tumours.
Brain Neoplasms
The expression of Gal beta 1,4GlcNAc alpha 2,6 sialyltransferase and alpha 2,6-linked sialoglycoconjugates in human brain tumors.
Breast Neoplasms
A transfected sialyltransferase that is elevated in breast cancer and localizes to the medial/trans-Golgi apparatus inhibits the development of core-2-based O-glycans.
Breast Neoplasms
alpha 2-6-Linked sialic acids on N-glycans modulate carcinoma differentiation in vivo.
Breast Neoplasms
Alterations in serum glycosyltransferases and 5'-nucleotidase in breast cancer patients.
Breast Neoplasms
An alpha2,3 sialyltransferase (ST3Gal I) is elevated in primary breast carcinomas.
Breast Neoplasms
An In Vivo Functional Screen Identifies ST6GalNAc2 Sialyltransferase as a Breast Cancer Metastasis Suppressor.
Breast Neoplasms
Breast cancer cells expressing cancer-associated sialyl-Tn antigen have less capacity to develop osteolytic lesions in a mouse model of skeletal colonization.
Breast Neoplasms
Breast cancer markers: comparison between sialyltransferase and human mammary epithelial antigens (HME-Ags) for the detection of human breast tumors grafted in nude mice.
Breast Neoplasms
Clinical usefulness of alterations in sialic acid, sialyl transferase and sialoproteins in breast cancer.
Breast Neoplasms
Comprehensive Transcriptomic Analysis Identifies ST8SIA1 as a Survival-Related Sialyltransferase Gene in Breast Cancer.
Breast Neoplasms
Cyclooxygenase-2 enzyme induces the expression of the ?-2,3-sialyltransferase-3 (ST3Gal-I) in breast cancer.
Breast Neoplasms
Cyclooxygenase-2 induces the expression of the alpha 2,3 sialyltransferase-3 (ST3Gal-I) in breast cancer.
Breast Neoplasms
Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA.
Breast Neoplasms
Functional roles of sialylation in breast cancer progression through miR-26a/26b targeting ST8SIA4.
Breast Neoplasms
Gene expression of fucosyl- and sialyl-transferases which synthesize sialyl Lewisx, the carbohydrate ligands for E-selectin, in human breast cancer.
Breast Neoplasms
Identification and functional characterization of a human GalNAc [alpha]2,6-sialyltransferase with altered expression in breast cancer.
Breast Neoplasms
Immunohistochemical expression of blood group substances and related carbohydrate antigens in breast carcinoma.
Breast Neoplasms
Multiplex reverse transcription polymerase chain reaction assessment of sialyltransferase expression in human breast cancer.
Breast Neoplasms
Multiplex RT-PCR method for the analysis of the expression of human sialyltransferases: application to breast cancer cells.
Breast Neoplasms
Post-operative serum sialyltransferase levels and prognosis in breast cancer.
Breast Neoplasms
Prognostic value of tumoral sialyltransferase expression and circulating E-selectin concentrations in node-negative breast cancer patients.
Breast Neoplasms
Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation.
Breast Neoplasms
Regulation of sialyltransferase expression by estradiol and 4-OH-tamoxifen in the human breast cancer cell MCF-7.
Breast Neoplasms
Serum sialyltransferase and 5'-nucleotidase as reliable biomarkers in women with breast cancer.
Breast Neoplasms
ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3?/?-catenin signaling pathway.
Breast Neoplasms
ST6GalNAc I expression in MDA-MB-231 breast cancer cells greatly modifies their O-glycosylation pattern and enhances their tumourigenicity.
Breast Neoplasms
Stable expression of sialyl-Tn antigen in T47-D cells induces a decrease of cell adhesion and an increase of cell migration.
Breast Neoplasms
Sticking to Sugars at the Metastatic Site: Sialyltransferase ST6GalNAc2 Acts as a Breast Cancer Metastasis Suppressor.
Breast Neoplasms
Studies on sialyltransferase isoenzymes in plasma of patients with breast cancer.
Breast Neoplasms
The pattern of glycosyl- and sulfotransferase activities in cancer cell lines: a predictor of individual cancer-associated distinct carbohydrate structures for the structural identification of signature glycans.
Breast Neoplasms
The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and Is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.
Carcinogenesis
?2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/?-catenin pathway.
Carcinogenesis
alpha 2-6-Linked sialic acids on N-glycans modulate carcinoma differentiation in vivo.
Carcinogenesis
Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
Carcinogenesis
Clinical significance of ST3Gal IV expression in human renal cell carcinoma.
Carcinogenesis
Development of Monoclonal Antibodies against CMP-N-Acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3Gal-I) Recombinant Protein Expressed in E. coli.
Carcinogenesis
Elevation of alpha2-->6 sialyltransferase and alpha1-->2 fucosyltransferase activities in human choriocarcinoma.
Carcinogenesis
Glycosyltransferase expression in human colonic tissue examined by oligonucleotide arrays.
Carcinogenesis
ST6Gal-I Protein Expression Is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines.
Carcinogenesis
The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype.
Carcinoma
Adrenal carcinoma tumor progression and penultimate cell surface oligosaccharides.
Carcinoma
Alterations in plasma sialyltransferase associated with successful chemotherapy of a disseminated tumor. Case report.
Carcinoma
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Carcinoma
Altered mRNA expression of sialyltransferase in squamous cell carcinomas of the cervix.
Carcinoma
Carcinoembryonic antigen carrying SLeX as a new biomarker of more aggressive gastric carcinomas.
Carcinoma
CDX2 homeoprotein is involved in the regulation of ST6GalNAc-I gene in intestinal metaplasia.
Carcinoma
Colon carcinoma glycoproteins carrying alpha 2,6-linked sialic acid reactive with Sambucus nigra agglutinin are not constitutively expressed in normal human colon mucosa and are distinct from sialyl-Tn antigen.
Carcinoma
Different sialyltransferase activities in human colorectal carcinoma cells from surgical specimens detected by specific glycoprotein and glycolipid acceptors.
Carcinoma
Expression of alpha 2,6-sialylated sugar chains in normal and neoplastic colon tissues. Detection by digoxigenin-conjugated Sambucus nigra agglutinin.
Carcinoma
Expression of sialyl-Tn epitopes on beta1 integrin alters epithelial cell phenotype, proliferation and haptotaxis.
Carcinoma
Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis.
Carcinoma
Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer.
Carcinoma
Molecular cloning of a developmentally regulated N-acetylgalactosamine alpha2,6-sialyltransferase specific for sialylated glycoconjugates.
Carcinoma
Monoclonal antibodies raised against NeuAc alpha 2-6neolactotetraosylceramide detect carcinoma-associated gangliosides.
Carcinoma
Reversibility of retinoid effect on sialyltransferase activity, sialic acid content and invasive ability of human lung carcinoma cells.
Carcinoma
Sialylation of beta1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis.
Carcinoma
Sialylation of the Fas death receptor by ST6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma cells.
Carcinoma
Sialyltransferase levels and ganglioside expression in melanoma and other cultured human cancer cells.
Carcinoma
ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function.
Carcinoma
ST6Gal-I predicts postoperative clinical outcome for patients with localized clear-cell renal cell carcinoma.
Carcinoma
ST6Gal-I Protein Expression Is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines.
Carcinoma
ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.
Carcinoma
The expression of soluble and cell-bound alpha 2,6 sialyltransferase in human colonic carcinoma CaCo-2 cells correlates with the degree of enterocytic differentiation.
Carcinoma
The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype.
Carcinoma
[Combinatorial effects of ST6Gal I siRNA and antisense oligonucleotide-mediated gene silence on metastasis ability of cervical carcinoma cells]
Carcinoma
[Significance of alpha 2,6-specific sialyltransferase ST6N and alpha 2,3-specific sialyltransferase ST3N in stomach carcinoma]
Carcinoma, Bronchogenic
Serum sialyltransferase and fucosyltransferase activities in patients with bronchial carcinoma.
Carcinoma, Hepatocellular
?2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/?-catenin pathway.
Carcinoma, Hepatocellular
Activity and characterization of sialyltransferase from serum of normal rats, of rats bearing Zajdela ascitic hepatoma, in normal host liver and in Zajdela hepatoma cells.
Carcinoma, Hepatocellular
Biosynthesis and intracellular transport of alpha-2,6-sialyltransferase in rat hepatoma cells.
Carcinoma, Hepatocellular
Characterization of galactosyltransferase released from human hepatoma cells.
Carcinoma, Hepatocellular
Characterization of glycosyltransferases in the Golgi complex from rat ascites hepatoma AH-130 cells: a comparison with those from normal liver.
Carcinoma, Hepatocellular
Characterization of sialyltransferases from serum of normal and hepatoma Mc-29 bearing chickens.
Carcinoma, Hepatocellular
Codistribution of galactosyl- and sialyltransferase: reorganization of trans Golgi apparatus elements in hepatocytes in intact liver and cell culture.
Carcinoma, Hepatocellular
Comparative study of the levels of sialyltransferases responsible for the formation of sugar chains in glycoproteins and gangliosides in rat liver and hepatomas.
Carcinoma, Hepatocellular
Distribution of glycosyltransferases among Golgi apparatus subfractions from liver and hepatomas of the rat.
Carcinoma, Hepatocellular
Enhanced expression of ganglioside GD3 in human and rat hepatocellular carcinoma cells and NIH 3T3 cells transfected with human tumor DNAs.
Carcinoma, Hepatocellular
Gangliosides of liver tumors induced by N-2 fluorenylacetamide III. Galactosyl and sialyl transferases in single carcinomas and nodules.
Carcinoma, Hepatocellular
Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.
Carcinoma, Hepatocellular
Increase in serum sialyltransferase in tumor-bearing rats: the origin and nature of the increased enzyme.
Carcinoma, Hepatocellular
Modification of sialylation mediates the invasive properties and chemosensitivity of human hepatocellular carcinoma.
Carcinoma, Hepatocellular
Modification of Sialylation Mediates the Invasive Properties and Chemosensitivity of Human Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Multiple forms of chicken liver and hepatoma Mc-29 microsomal and plasma-membrane sialyl and fucosyltransferases.
Carcinoma, Hepatocellular
Partial characterization of microsomal sialyltransferase from chicken liver and hepatoma Mc-29: I. Effect of nucleotides and metal ions.
Carcinoma, Hepatocellular
Partial characterization of microsomal sialyltransferase from chicken liver and hepatoma Mc-29: II. Measurement of enzyme activities utilizing microsomal glycoproteins as exogenous acceptors.
Carcinoma, Hepatocellular
Purification and characterization of beta-galactoside (alpha 2 leads to 6)sialyltransferase from rat liver and hepatomas.
Carcinoma, Hepatocellular
Regulation of beta-galactoside alpha 2,6-sialyltransferase gene expression by dexamethasone.
Carcinoma, Hepatocellular
Sialyltransferase ST3GAL6 mediates the effect of microRNA-26a on cell growth, migration, and invasion in hepatocellular carcinoma through the protein kinase B/mammalian target of rapamycin pathway.
Carcinoma, Hepatocellular
ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway.
Carcinoma, Hepatocellular
ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3?/?-catenin signaling pathway.
Carcinoma, Hepatocellular
Stimulation of release of Gal beta 1-4GlcNAc alpha 2-6 sialyltransferase from the FAZA hepatoma cell line by dexamethasone and phorbol ester.
Carcinoma, Hepatocellular
The biochemical consequences of alpha2,6(N) sialyltransferase induction by dexamethasone on sialoglycoprotein expression in the rat H411e hepatoma cell line.
Carcinoma, Hepatocellular
The clinical and physiological implications of hepatoma B12-binding proteins.
Carcinoma, Hepatocellular
The specific release of sialytransferase activity by human hepatoma cell lines.
Carcinoma, Non-Small-Cell Lung
Modification of ?2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
Carcinoma, Papillary
Immunohistochemical study of type-1 blood antigen expressions in thyroid tumors: the significance for papillary carcinomas.
Carcinoma, Renal Cell
ST6Gal-I predicts postoperative clinical outcome for patients with localized clear-cell renal cell carcinoma.
Carcinoma, Squamous Cell
Altered mRNA expression of sialyltransferase in squamous cell carcinomas of the cervix.
Carcinoma, Squamous Cell
Effect of retinoic acid and phorbol-12-myristate-13-acetate on glycosyltransferase activities in normal and transformed cells.
Carcinoma, Squamous Cell
Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis.
Carcinoma, Squamous Cell
Sialyltransferase family members and cervix squamous cell carcinoma.
Cardiomyopathies
Excitation-contraction coupling in normal and myopathic hamster hearts III: functional deficiencies in interstitial glycoproteins.
Cardiomyopathies
Orotic acid prevents changes in cardiac sarcolemmal glycoproteins and contractility associated with muscular dystrophy in hamsters.
Cataract
Kidney sialidase and sialyltransferase activities in spontaneously and experimentally diabetic rats. Influence of insulin and sorbinil treatments.
Choriocarcinoma
Elevation of alpha2-->6 sialyltransferase and alpha1-->2 fucosyltransferase activities in human choriocarcinoma.
Colonic Neoplasms
Correlation analysis between tumor-associated antigen sialyl-Tn expression and ST6GalNAc I activity in human colon adenocarcinoma.
Colonic Neoplasms
Enhanced CMP-NeuAc:Gal beta 1,4GlcNAc-R alpha 2,6 sialyltransferase activity of human colon cancer xenografts in athymic nude mice and of xenograft-derived cell lines.
Colonic Neoplasms
Human colon cancer cell lines permanently expressing alpha 2,6-sialylated sugar chains by transfection with rat beta-galactoside alpha 2,6 sialyltransferase cDNA.
Colonic Neoplasms
Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility.
Colonic Neoplasms
Impact of sialyltransferase ST6GAL1 overexpression on different colon cancer cell types.
Colonic Neoplasms
Inhibition of experimental pulmonary metastasis of mouse colon adenocarcinoma 26 sublines by a sialic acid:nucleoside conjugate having sialyltransferase inhibiting activity.
Colonic Neoplasms
n-butyrate reduces the expression of beta-galactoside alpha 2,6-sialyltransferase in Hep G2 cells.
Colonic Neoplasms
Possible mechanism of inhibition of experimental pulmonary metastasis of mouse colon adenocarcinoma 26 sublines by a sialic acid: nucleoside conjugate.
Colonic Neoplasms
Sialylation of epidermal growth factor receptor regulates receptor activity and chemosensitivity to gefitinib in colon cancer cells.
Colonic Neoplasms
ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function.
Colonic Neoplasms
ST6Gal-I Protein Expression Is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines.
Colonic Neoplasms
Suppression of a sialyltransferase by antisense DNA reduces invasiveness of human colon cancer cells in vitro.
Colonic Neoplasms
Synthesis of disialyl Lewis a (Le(a)) structure in colon cancer cell lines by a sialyltransferase, ST6GalNAc VI, responsible for the synthesis of alpha-series gangliosides.
Colonic Neoplasms
The pattern of glycosyl- and sulfotransferase activities in cancer cell lines: a predictor of individual cancer-associated distinct carbohydrate structures for the structural identification of signature glycans.
Colonic Neoplasms
Tumor cell migration and invasion are regulated by expression of variant integrin glycoforms.
Colonic Neoplasms
[Structures, synthesis and functions of sialyl Le(a)/sialyl Le(x) antigens]
Colorectal Neoplasms
Alpha 2,6 sialylation of N-acetyllactosaminic sequences in human colorectal cancer cell lines. Relationship with non-adherent growth.
Colorectal Neoplasms
Alterations of CMP-NeuAc:asialofetuin sialyltransferase activities in human colorectal adenocarcinoma.
Colorectal Neoplasms
Altered mRNA expression of specific molecular species of fucosyl- and sialyl-transferases in human colorectal cancer tissues.
Colorectal Neoplasms
Correlation analysis between tumor-associated antigen sialyl-Tn expression and ST6GalNAc I activity in human colon adenocarcinoma.
Colorectal Neoplasms
Different sialyltransferase activities in human colorectal carcinoma cells from surgical specimens detected by specific glycoprotein and glycolipid acceptors.
Colorectal Neoplasms
Elevation of ST6Gal I activity in malignant and transitional tissue in human colorectal cancer.
Colorectal Neoplasms
Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility.
Colorectal Neoplasms
Increased CMP-NeuAc:Gal beta 1,4GlcNAc-R alpha 2,6 sialyltransferase activity in human colorectal cancer tissues.
Colorectal Neoplasms
Overexpression of sialyltransferase CMP-sialic acid:Galbeta1,3GalNAc-R alpha6-Sialyltransferase is related to poor patient survival in human colorectal carcinomas.
Colorectal Neoplasms
Purification and characterization of a CMP-sialic:LcOse4Cer sialyltransferase from human colorectal carcinoma cell membranes.
Colorectal Neoplasms
Sialylation of epidermal growth factor receptor regulates receptor activity and chemosensitivity to gefitinib in colon cancer cells.
Colorectal Neoplasms
Sialyltransferase activity and hepatic tumor growth in a nude mouse model of colorectal cancer metastases.
Colorectal Neoplasms
The glycosyltransferase ST6Gal-I is enriched in cancer stem-like cells in colorectal carcinoma and contributes to their chemo-resistance.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Sialylation regulates brain structure and function.
Cystic Fibrosis
Comparison of the polypeptide composition of cystic fibrosis plasma with normal plasma by high resolution electrophoresis.
Cystic Fibrosis
Cystic fibrosis transmembrane conductance regulator and H+ permeability in regulation of Golgi pH.
Demyelinating Diseases
Ectopic expression of polysialylated neural cell adhesion molecule in adult macaque Schwann cells promotes their migration and remyelination potential in the central nervous system.
Dermatitis, Contact
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Epilepsy, Temporal Lobe
Sialyltransferase ST3Gal IV deletion protects against temporal lobe epilepsy.
Esophageal Neoplasms
Identification of the expression profile of apoptotic esophageal cancer cells by adenoviral-fragile histidine triad treatment.
Glioblastoma
ST3GAL1-Associated Transcriptomic Program in Glioblastoma Tumor Growth, Invasion, and Prognosis.
Glioma
Effect of desipramine on a glycoprotein sialyltransferase activity in C6 cultured glioma cells.
Glioma
Effect of retinoic acid on two glycosyltransferase activities in C6 cultured glioma cells.
Glioma
Increased tumorigenicity and invasiveness of C6 rat glioma cells transfected with the human alpha-2,8 sialyltransferase cDNA.
Glioma
Study of O-glycan sialylation in C6 cultured glioma cells: evidence for post-translational regulation of a beta-galactoside alpha 2,3 sialyltransferase activity by N-glycosylation.
Glioma
Study of O-glycan sialylation in C6 cultured glioma cells: regulation of a beta-galactoside alpha 2,3 sialyltransferase activity by Ca2+/calmodulin antagonists and phosphatase inhibitors.
Glioma
Study of O-sialylation of glycoproteins in C6 glioma cells treated with retinoic acid.
Goiter, Endemic
Hyposialylated thyroglobulin in a patient with congenital goiter and hypothyroidism.
Gonorrhea
The Lst Sialyltransferase of Neisseria gonorrhoeae Can Transfer Keto-Deoxyoctanoate as the Terminal Sugar of Lipooligosaccharide: a Glyco-Achilles Heel That Provides a New Strategy for Vaccines to Prevent Gonorrhea.
Graves Disease
Thyroid sialyltransferase mRNA level and activity are increased in Graves' disease.
Guillain-Barre Syndrome
Campylobacter sialyltransferase gene polymorphism directs clinical features of Guillain-Barré syndrome.
Guillain-Barre Syndrome
Miller-Fisher syndrome associated with Campylobacter jejuni bearing lipopolysaccharide molecules that mimic human ganglioside GD3.
Guillain-Barre Syndrome
[Campylobacter genes responsible for the development and determinant of clinical features of Guillain-Barré syndrome]
Heart Failure
Aberrant sialylation causes dilated cardiomyopathy and stress-induced heart failure.
Hepatitis B
[Regulation of Gal beta 1,3GalNAc alpha 2,3-sialyltransferase (ST3GalI) by hepatitis B virus MHBst/HBx transactivator]
Hepatoblastoma
n-Butyrate mediation of ganglioside expression of human and murine cancer cells demonstrates relative cell specificity.
Hypertension, Pulmonary
Multiplex reverse transcription polymerase chain reaction assessment of sialyltransferase expression in peripheral blood mononuclear cells in systemic sclerosis.
Infections
?2,6-linked sialic acid serves as a high-affinity receptor for cancer oncolytic virotherapy with Newcastle disease virus.
Infections
An N-linked glycoprotein with alpha(2,3)-linked sialic acid is a receptor for BK virus.
Infections
Differential infection of receptor-modified host cells by receptor-specific influenza viruses.
Infections
Elevated glycosyltransferase activities in infected or traumatized hosts: nonspecific response to inflammation.
Infections
Legless pathogens: how bacterial physiology provides the key to understanding pathogenicity.
Infections
Non-culture diagnosis and serogroup determination of meningococcal B and C infection by a sialyltransferase (siaD) PCR ELISA.
Infections
Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes.
Infections
Sialylation of lipooligosaccharides is dispensable for the virulence of Haemophilus ducreyi in humans.
Infertility
[Sialyltransferase activity in the spermatic membrane and its relation to human fertility and sterility]
Infertility, Male
Seminal plasma biochemistry II: seminal plasma and spermatozoal cytidine monophosphate-sialic acid synthetase and sialyltransferase activities.
Influenza in Birds
Inhibition of H5N1 highly pathogenic influenza virus by suppressing a specific sialyltransferase.
Influenza, Human
Characterization of sialyltransferases from serum of normal and hepatoma Mc-29 bearing chickens.
Influenza, Human
Inhibition of H5N1 highly pathogenic influenza virus by suppressing a specific sialyltransferase.
Influenza, Human
Overexpression of ?-2,6 sialyltransferase stimulates propagation of human influenza viruses in Vero cells.
Influenza, Human
The expression of essential components for human influenza virus internalisation in Vero and MDCK cells.
Influenza, Human
The hemagglutinins of the human influenza viruses A and B recognize different receptor microdomains.
Influenza, Human
The signal anchor and stem regions of the beta-galactoside alpha 2,6-sialyltransferase may each act to localize the enzyme to the Golgi apparatus.
Influenza, Human
Transfer of synthetic sialic acid analogues to N- and O-linked glycoprotein glycans using four different mammalian sialyltransferases.
Insulin Resistance
Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance.
Kidney Neoplasms
Identification and expression of a sialyltransferase responsible for the synthesis of disialylgalactosylgloboside in normal and malignant kidney cells: downregulation of ST6GalNAc VI in renal cancers.
Leukemia
Glycosyltransferase activities in leukemic cells from patients and human leukemic cell lines.
Leukemia
Role of clathrin-coated vesicles in glycoprotein transport from the cell surface to the Golgi complex.
Leukemia
Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes.
Leukemia, Lymphocytic, Chronic, B-Cell
Some properties of sialyltransferase in plasma and lymphocytes of patients with chronic lymphocytic leukemia.
Leukemia, Lymphoid
12-0-Tetradecanoylphorbol 13-acetate (TPA)-induced enzymatic change of human non-T, non-B lymphoid leukemia cell lines.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Increased activity of a specific sialyltransferase in chronic myelogenous leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Presence of cytidine 5'-monophospho-N-acetylneuraminic acid:Gal beta 1-3GalNAc-R alpha(2-3)-sialyltransferase in normal human leukocytes and increased activity of this enzyme in granulocytes from chronic myelogenous leukemia patients.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Sialyltransferase activity as a marker for the differentiation of lymphocytes. Increase in sialyltransferase activity of blasts from acute lymphoblastic leukaemia cases by 12-o-tetradecanoylphorbol-13-acetate (TPA).
Liver Cirrhosis
Cytidine-5'-monophosphate-N-acetylneuraminic acid. Asialoglycoprotein sialic acid transferase activity in liver and serum of patients with juvenile hepatic cirrhosis and alpha-1-antitrypsin deficiency.
Liver Cirrhosis
Demonstration of sialyltransferase deficiency in the serum of a patient with alpha-1-antitrypsin deficiency and hepatic cirrhosis.
Liver Diseases
Cytidine-5'-monophosphate-N-acetylneuraminic acid. Asialoglycoprotein sialic acid transferase activity in liver and serum of patients with juvenile hepatic cirrhosis and alpha-1-antitrypsin deficiency.
Liver Diseases
[Analysis of serum sialyltransferase activities, with special reference to the fluctuations in liver diseases]
Liver Neoplasms
The pattern of glycosyl- and sulfotransferase activities in cancer cell lines: a predictor of individual cancer-associated distinct carbohydrate structures for the structural identification of signature glycans.
Lung Diseases
Serum sialyltransferase and fucosyltransferase activities in patients with bronchial carcinoma.
Lung Neoplasms
A novel sialyltransferase inhibitor AL10 suppresses invasion and metastasis of lung cancer cells by inhibiting integrin-mediated signaling.
Lung Neoplasms
Comparative study of the levels of sialyltransferases responsible for the formation of sugar chains in glycoproteins and gangliosides in rat liver and hepatomas.
Lung Neoplasms
Correlation between plasma carcinoembryonic antigen (CEA) and sialyltransferase as tumor marker.
Lung Neoplasms
Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition.
Lung Neoplasms
Modification of ?2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
Lung Neoplasms
Multiplexed surrogate analysis of glycotransferase activity in whole biospecimens.
Lupus Erythematosus, Systemic
Sialyltransferase and Neuraminidase Levels/Ratios and Sialic Acid Levels in Peripheral Blood B Cells Correlate with Measures of Disease Activity in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Pilot Study.
Lupus Erythematosus, Systemic
ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling.
Lymphatic Metastasis
Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis.
Lymphoma
[Serum sialyltransferase activity: a possible aid in the staging and course control of malignant lymphomas]
Lymphoma, Non-Hodgkin
Role of sialyltransferase in hypercupraemia of non-Hodgkin's lymphoma.
Melanoma
A correlation between cell surface sialyltransferase, sialic acid, and glycosidase activities and the implantability of B16 murine melanoma.
Melanoma
Alterations of cell surface carbohydrates and inhibition of metastatic property of murine melanomas by alpha 1,3 galactosyltransferase gene transfection.
Melanoma
Cell surface sialylation and tumor metastasis. Metastatic potential of B16 melanoma variants correlates with their relative numbers of specific penultimate oligosaccharide structures.
Melanoma
Characterization of two glycolipid: alpha 2-3sialyltransferases, SAT-3 (CMP-NeuAc:nLcOse4Cer alpha 2-3sialyltransferase) and SAT-4 (CMP-NeuAc:GgOse4Cer alpha 2-3sialyltransferase), from human colon carcinoma (Colo 205) cell line.
Melanoma
Correlation of retinoic acid-enhanced sialyltransferase activity and glycosylation of specific cell surface sialoglycoproteins with growth inhibition in a murine melanoma cell system.
Melanoma
Deficiency of ganglioside biosynthesis in metastatic human melanoma cells: relevance of CMP-NeuAc:LacCer alpha 2-3 sialyltransferase (GM3 synthase).
Melanoma
Down-regulation of GD3 ganglioside and its O-acetylated derivative by stable transfection with antisense vector against GD3-synthase gene expression in hamster melanoma cells: effects on cellular growth, melanogenesis, and dendricity.
Melanoma
Enhancement of sialyltransferase in two melanoma cell lines that are growth-inhibited by retinoic acid results in increased sialylation of different cell-surface glycoproteins.
Melanoma
Growth inhibition of murine melanoma cells by antibodies to a cell surface glycoprotein implicated in retinoic acid action.
Melanoma
Neobiosynthesis of glycosphingolipids by plasma membrane-associated glycosyltransferases.
Melanoma
Serum sialic acid and sialyltransferase as monitors of tumor burden in malignant melanoma patients.
Melanoma
Serum sialyltransferase and liver catalase activity in cachectic nude mice bearing a human malignant melanoma.
Melanoma
Sialyltransferase levels and ganglioside expression in melanoma and other cultured human cancer cells.
Melanoma
Sialyltransferase levels and sialic acid concentrations in sera of patients with malignant melanomas.
Melanoma
ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL.
Melanoma
[Clinical significant of sialic acid concentrations in the serum of melanoma patients]
Meningitis
Site-specific immobilization of enzymes on magnetic nanoparticles and their use in organic synthesis.
Meningococcal Infections
siaD PCR ELISA for confirmation and identification of serogroup Y and W135 meningococcal infections.
Miller Fisher Syndrome
Guillain-Barré syndrome and anti-ganglioside antibodies: a clinician-scientist's journey.
Monoclonal Gammopathy of Undetermined Significance
Sialyltransferase activity and sialic acid levels in multiple myeloma and monoclonal gammopathy.
Mouth Neoplasms
"Aberrant sialylation plays a significant role in oral squamous cell carcinoma progression".
Multiple Myeloma
Serum sialyltransferase and fucosyltransferase activities in patients with multiple myeloma.
Multiple Myeloma
Sialyltransferase activity and sialic acid levels in multiple myeloma and monoclonal gammopathy.
Multiple Myeloma
Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model.
Multiple Myeloma
The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma.
Myasthenia Gravis
Possible relationship between poly(ADP-ribose)synthetase and formation of antibody against acetylcholine receptors in patients with myasthenia gravis.
Myotonic Dystrophy
Sialyltransferase activity in erythrocyte membranes and serum in patients with myotonic dystrophy.
Myxoma
Post-translational modification of the myxoma-virus anti-inflammatory serpin SERP-1 by a virally encoded sialyltransferase.
n-acetyllactosaminide alpha-2,3-sialyltransferase deficiency
Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands.
Neoplasm Metastasis
?2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/?-catenin pathway.
Neoplasm Metastasis
A novel sialyltransferase inhibitor AL10 suppresses invasion and metastasis of lung cancer cells by inhibiting integrin-mediated signaling.
Neoplasm Metastasis
A novel sialyltransferase inhibitor suppresses FAK/paxillin signaling and cancer angiogenesis and metastasis pathways.
Neoplasm Metastasis
Alterations in serum sialyltransferase activities in patients with brain tumors.
Neoplasm Metastasis
An In Vivo Functional Screen Identifies ST6GalNAc2 Sialyltransferase as a Breast Cancer Metastasis Suppressor.
Neoplasm Metastasis
Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis.
Neoplasm Metastasis
Glycosyltransferase expression in human colonic tissue examined by oligonucleotide arrays.
Neoplasm Metastasis
Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility.
Neoplasm Metastasis
Inhibition of experimental pulmonary metastasis of mouse colon adenocarcinoma 26 sublines by a sialic acid:nucleoside conjugate having sialyltransferase inhibiting activity.
Neoplasm Metastasis
Insights into the role of sialylation in cancer progression and metastasis.
Neoplasm Metastasis
Knockdown of ST6Gal-I increases cisplatin sensitivity in cervical cancer cells.
Neoplasm Metastasis
Modification of ?2,6-sialylation mediates the invasiveness and tumorigenicity of non-small cell lung cancer cells in vitro and in vivo via Notch1/Hes1/MMPs pathway.
Neoplasm Metastasis
Overexpression of sialyltransferase CMP-sialic acid:Galbeta1,3GalNAc-R alpha6-Sialyltransferase is related to poor patient survival in human colorectal carcinomas.
Neoplasm Metastasis
Plasma sialyl transferase total and isoenzyme activity in the diagnosis of cancer of the colon.
Neoplasm Metastasis
Possible mechanism of inhibition of experimental pulmonary metastasis of mouse colon adenocarcinoma 26 sublines by a sialic acid: nucleoside conjugate.
Neoplasm Metastasis
RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells.
Neoplasm Metastasis
Sialylation of the Fas death receptor by ST6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma cells.
Neoplasm Metastasis
Sialyltransferase activity and hepatic tumor growth in a nude mouse model of colorectal cancer metastases.
Neoplasm Metastasis
Silencing of ST6GalNAc I suppresses the proliferation, migration and invasion of hepatocarcinoma cells through PI3K/AKT/NF-?B pathway.
Neoplasm Metastasis
ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function.
Neoplasm Metastasis
ST6Gal-I predicts postoperative clinical outcome for patients with localized clear-cell renal cell carcinoma.
Neoplasm Metastasis
ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells.
Neoplasm Metastasis
ST6GalNAc-I promotes lung cancer metastasis by altering MUC5AC sialylation.
Neoplasm Metastasis
Sticking to Sugars at the Metastatic Site: Sialyltransferase ST6GalNAc2 Acts as a Breast Cancer Metastasis Suppressor.
Neoplasm Metastasis
The expression of Gal beta 1,4GlcNAc alpha 2,6 sialyltransferase and alpha 2,6-linked sialoglycoconjugates in human brain tumors.
Neoplasms
?2,3-sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic adenocarcinoma tissues.
Neoplasms
?2,6-linked sialic acid serves as a high-affinity receptor for cancer oncolytic virotherapy with Newcastle disease virus.
Neoplasms
?2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/?-catenin pathway.
Neoplasms
?2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling.
Neoplasms
A correlation between cell surface sialyltransferase, sialic acid, and glycosidase activities and the implantability of B16 murine melanoma.
Neoplasms
A novel sialyltransferase inhibitor suppresses FAK/paxillin signaling and cancer angiogenesis and metastasis pathways.
Neoplasms
Activity and characterization of sialyltransferase from serum of normal rats, of rats bearing Zajdela ascitic hepatoma, in normal host liver and in Zajdela hepatoma cells.
Neoplasms
Advancement of Sialyltransferase Inhibitors: Therapeutic Challenges and Opportunities.
Neoplasms
alpha 2-6-Linked sialic acids on N-glycans modulate carcinoma differentiation in vivo.
Neoplasms
alpha2,3-sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo.
Neoplasms
Alteration of ganglioside composition by stable transfection with antisense vectors against GD3-synthase gene expression.
Neoplasms
Alterations in plasma sialyltransferase associated with successful chemotherapy of a disseminated tumor. Case report.
Neoplasms
Alterations in plasma sialyltransferase levels in patients with neoplastic disease.
Neoplasms
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Neoplasms
Biochemical evidence for the role of alkyl-lysophospholipids on liver sialyltransferase.
Neoplasms
Breast cancer markers: comparison between sialyltransferase and human mammary epithelial antigens (HME-Ags) for the detection of human breast tumors grafted in nude mice.
Neoplasms
Characterization of Cancer Associated Mucin Type O-Glycans Using the Exchange Sialylation Properties of Mammalian Sialyltransferase ST3Gal-II.
Neoplasms
Characterization of sialyltransferases from serum of normal and hepatoma Mc-29 bearing chickens.
Neoplasms
Characterization of sialytransferase in noncancerous and neoplastic human liver tissue.
Neoplasms
Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
Neoplasms
Clinical usefulness of alterations in sialic acid, sialyl transferase and sialoproteins in breast cancer.
Neoplasms
CMP-NeuAc:(NeuAc alpha 2-->8)n (colominic acid) sialyltransferase activity in rat brain and in tumour cells that express polysialic acid on neural cell adhesion molecules.
Neoplasms
Comparative study of the levels of sialyltransferases responsible for the formation of sugar chains in glycoproteins and gangliosides in rat liver and hepatomas.
Neoplasms
Concomitant elevations in serum sialytransferase activity and sialic acid content in rats with metastasizing mammary tumors.
Neoplasms
Correlation between plasma carcinoembryonic antigen (CEA) and sialyltransferase as tumor marker.
Neoplasms
Correlation of serum, tumor, and liver serum glycoprotein: N-acetylneuraminic acid transferase activity with growth of the R3230AC mammary tumor in rats and relationship of the serum activity to tumor burden.
Neoplasms
Defective thyroglobulin synthesis in an experimental rat thyroid tumor. Lack of membrane-bound sialyltransferase activity.
Neoplasms
Demonstration of endogenous sialyltransferase on the surface of ehrlich tumour ascites cells.
Neoplasms
Depletion of ST6GALNACIII retards A549 non-small cell lung cancer cell proliferation by downregulating transferrin receptor protein 1 expression.
Neoplasms
Development of Monoclonal Antibodies against CMP-N-Acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3Gal-I) Recombinant Protein Expressed in E. coli.
Neoplasms
Differences in the isoelectric focusing patterns of gamma-glutamyl transpeptidase from normal and cancerous rat mammary tissue.
Neoplasms
Different enzyme activities of sialyltransferases in gynecological cancer cell lines.
Neoplasms
Different sialyltransferase activities in human colorectal carcinoma cells from surgical specimens detected by specific glycoprotein and glycolipid acceptors.
Neoplasms
Disialyl GD2 ganglioside suppresses ICAM-1-mediated invasiveness in human breast cancer MDA-MB231 cells.
Neoplasms
Effect of retinoic acid and phorbol-12-myristate-13-acetate on glycosyltransferase activities in normal and transformed cells.
Neoplasms
Elevation of ratio of urinary N-acetylneuraminlactose to free sialic acid in some advanced cancer patients.
Neoplasms
Embryonic precancerous and cancerous human antigens recognized by monoclonal antibodies.
Neoplasms
Enhanced activity of CMP-neuAc:Gal beta 1-4GlcNAc:alpha 2,6-sialyltransferase in metastasizing human colorectal tumor tissue and serum of tumor patients.
Neoplasms
Enhancement of metastatic ability by ectopic expression of ST6GalNAcI on a gastric cancer cell line in a mouse model.
Neoplasms
Evaluation of serum sialic acid, sialyltransferase and sialoproteins in oral cavity cancer.
Neoplasms
Glycoproteomic identification of potential glycoprotein biomarkers in ovarian cancer proximal fluids.
Neoplasms
Glycosyltransferase levels in tumors metastatic to liver and in uninvolved liver tissue.
Neoplasms
Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells.
Neoplasms
Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates.
Neoplasms
Identification and functional characterization of a human GalNAc [alpha]2,6-sialyltransferase with altered expression in breast cancer.
Neoplasms
Immunohistochemical expression of blood group substances and related carbohydrate antigens in breast carcinoma.
Neoplasms
Immunohistochemical study of type-1 blood antigen expressions in thyroid tumors: the significance for papillary carcinomas.
Neoplasms
Increase in serum sialyltransferase in tumor-bearing rats: the origin and nature of the increased enzyme.
Neoplasms
Increased alpha2,6 sialylation of N-glycans in a transgenic mouse model of hepatocellular carcinoma.
Neoplasms
Increased CMP-NeuAc:Gal beta 1,4GlcNAc-R alpha 2,6 sialyltransferase activity in human colorectal cancer tissues.
Neoplasms
Inhibition of experimental pulmonary metastasis of mouse colon adenocarcinoma 26 sublines by a sialic acid:nucleoside conjugate having sialyltransferase inhibiting activity.
Neoplasms
Loss of disialyl Lewis(a), the ligand for lymphocyte inhibitory receptor sialic acid-binding immunoglobulin-like lectin-7 (Siglec-7) associated with increased sialyl Lewis(a) expression on human colon cancers.
Neoplasms
Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells.
Neoplasms
Modification of sialylation mediates the invasive properties and chemosensitivity of human hepatocellular carcinoma.
Neoplasms
Modification of Sialylation Mediates the Invasive Properties and Chemosensitivity of Human Hepatocellular Carcinoma.
Neoplasms
Modulation of glycosyltransferase ST6Gal-I in gastric cancer-derived organoids disrupts homeostatic epithelial cell turnover.
Neoplasms
O-glycan sialylation alters galectin-3 subcellular localization and decreases chemotherapy sensitivity in gastric cancer.
Neoplasms
Overexpression of ?2,3sialyl T-antigen in breast cancer determined by miniaturized glycosyltransferase assays and confirmed using tissue microarray immunohistochemical analysis.
Neoplasms
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Neoplasms
Possible mechanism of inhibition of experimental pulmonary metastasis of mouse colon adenocarcinoma 26 sublines by a sialic acid: nucleoside conjugate.
Neoplasms
Prognostic significance of ST6GalNAc-1 expression in patients with non-metastatic clear cell renal cell carcinoma.
Neoplasms
Promoter Polymorphisms of ST3GAL4 and ST6GAL1 Genes and Associations with Risk of Premalignant and Malignant Lesions of the Cervix.
Neoplasms
Representational difference analysis in a lupus-prone mouse strain results in the identification of an unstable region of the genome on chromosome 11.
Neoplasms
Ricin and lentil lectin-affinity chromatography reveals oligosaccharide heterogeneity of thyrotropin secreted by 12 human pituitary tumors.
Neoplasms
RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells.
Neoplasms
Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen.
Neoplasms
Serum sialic acid and sialyltransferase as monitors of tumor burden in malignant melanoma patients.
Neoplasms
Serum sialyltransferase and 5'-nucleotidase as reliable biomarkers in women with breast cancer.
Neoplasms
Serum sialyltransferase and fucosyltransferase activities in patients with multiple myeloma.
Neoplasms
Serum sialyltransferase and liver catalase activity in cachectic nude mice bearing a human malignant melanoma.
Neoplasms
Serum sialyltransferase levels as a parameter in the diagnosis and follow-up of gastrointestinal tumors.
Neoplasms
Sialic Acid and Sialyltransferase Activity in Serum and Tissues of Dogs With Mammary Tumors.
Neoplasms
Sialic acid metabolism in rats undergoing chemically-induced mammary gland carcinogenesis in specific dietary states.
Neoplasms
Sialylation of beta1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis.
Neoplasms
Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death.
Neoplasms
Sialylation of epidermal growth factor receptor regulates receptor activity and chemosensitivity to gefitinib in colon cancer cells.
Neoplasms
Sialylation of FGFR1 by ST6Gal?I overexpression contributes to ovarian cancer cell migration and chemoresistance.
Neoplasms
Sialylation of the Fas death receptor by ST6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma cells.
Neoplasms
Sialyltransferase activity and hepatic tumor growth in a nude mouse model of colorectal cancer metastases.
Neoplasms
Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model.
Neoplasms
Sialyltransferase levels and ganglioside expression in melanoma and other cultured human cancer cells.
Neoplasms
Sialyltransferase levels and sialic acid concentrations in sera of patients with malignant melanomas.
Neoplasms
Sialyltransferase ST3GAL1 promotes cell migration, invasion, and TGF-?1-induced EMT and confers paclitaxel resistance in ovarian cancer.
Neoplasms
Sialyltransferase, sialic acid and sialoglycoconjugates in metastatic tumor and human liver tissue.
Neoplasms
Siglec1-expressing subcapsular sinus macrophages provide soil for melanoma lymph node metastasis.
Neoplasms
Silencing of ST6GalNAc I suppresses the proliferation, migration and invasion of hepatocarcinoma cells through PI3K/AKT/NF-?B pathway.
Neoplasms
Sox2 promotes expression of the ST6Gal-I glycosyltransferase in ovarian cancer cells.
Neoplasms
Soyasaponin-I-modified invasive behavior of cancer by changing cell surface sialic acids.
Neoplasms
ST3GAL1-Associated Transcriptomic Program in Glioblastoma Tumor Growth, Invasion, and Prognosis.
Neoplasms
ST3Gal3 confers paclitaxel?mediated chemoresistance in ovarian cancer cells by attenuating caspase?8/3 signaling.
Neoplasms
ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function.
Neoplasms
ST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway.
Neoplasms
ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3?/?-catenin signaling pathway.
Neoplasms
ST6Gal-I predicts postoperative clinical outcome for patients with localized clear-cell renal cell carcinoma.
Neoplasms
ST6Gal-I Protein Expression Is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines.
Neoplasms
ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor.
Neoplasms
Sticking to Sugars at the Metastatic Site: Sialyltransferase ST6GalNAc2 Acts as a Breast Cancer Metastasis Suppressor.
Neoplasms
The control of sialyltransferase activity in tumor-cell lines derived from different tissues in multifactorial.
Neoplasms
The glycosyltransferase ST6Gal-I is enriched in cancer stem-like cells in colorectal carcinoma and contributes to their chemo-resistance.
Neoplasms
The Glycosyltransferase ST6Gal-I Protects Tumor Cells against Serum Growth Factor Withdrawal by Enhancing Survival Signaling and Proliferative Potential.
Neoplasms
The ST6Gal-I sialyltransferase protects tumor cells against hypoxia by enhancing HIF-1? signaling.
Neoplasms
The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype.
Neoplasms
TNF up-regulates ST3GAL4 and sialyl-Lewisx expression in lung epithelial cells through an intronic ATF2-responsive element.
Neoplasms
Triple-negative and HER2-overexpressing breast cancer cell sialylation impacts tumor microenvironment T-lymphocyte subset recruitment: a possible mechanism of tumor escape.
Neoplasms
Tumor cell migration and invasion are regulated by expression of variant integrin glycoforms.
Neoplasms
[Clinical significant of sialic acid concentrations in the serum of melanoma patients]
Neoplasms
[Elevated serum-sialyltransferase activity in human malignant diseases: a new diagnostic tool? (author's transl)]
Neurilemmoma
Alterations in serum sialyltransferase activities in patients with brain tumors.
Neuroblastoma
Alteration of ganglioside composition by stable transfection with antisense vectors against GD3-synthase gene expression.
Neuroblastoma
Effect of membrane lipids on the lactosylceramide molecular species specificity of CMP-N-acetylneuraminate:lactosylceramide sialyltransferase.
Neuroblastoma
Overexpression of alpha2,3 sialyltransferase in neuroblastoma cells results in an upset in the glycosylation process.
Neuroblastoma
Overexpression of the alpha2,6 (N) sialyltransferase enzyme in human and rat neural cell lines is associated with increased expression of the polysialic acid epitope.
Neuroblastoma
Retinoic acid induction of sialyltransferase activity in neuroblastoma cells of differing sialylation potentials.
Neuroblastoma
Sialyltransferase levels and ganglioside expression in melanoma and other cultured human cancer cells.
Neuroblastoma
Sialyltransferase STX (ST8SiaII): a novel molecular marker of metastatic neuroblastoma.
Neuroblastoma
The generation and characterization of a rat neural cell line overexpressing the alpha2,6(N) sialyltransferase.
Obesity
Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance.
Oligospermia
Seminal plasma biochemistry II: seminal plasma and spermatozoal cytidine monophosphate-sialic acid synthetase and sialyltransferase activities.
Osteosarcoma
Knockdown of ST6Gal-I inhibits the growth and invasion of osteosarcoma MG-63 cells.
Otitis Media
Host-derived sialic acid is incorporated into Haemophilus influenzae lipopolysaccharide and is a major virulence factor in experimental otitis media.
Ovarian Neoplasms
A glycosphingolipid/caveolin-1 signaling complex inhibits motility of human ovarian carcinoma cells.
Ovarian Neoplasms
Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death.
Ovarian Neoplasms
Sialyltransferase and nucleoside diphosphatase as markers for tumor monitoring.
Ovarian Neoplasms
Sialyltransferase ST3GAL1 promotes cell migration, invasion, and TGF-?1-induced EMT and confers paclitaxel resistance in ovarian cancer.
Ovarian Neoplasms
Sox2 promotes expression of the ST6Gal-I glycosyltransferase in ovarian cancer cells.
Ovarian Neoplasms
ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function.
Ovarian Neoplasms
ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3?/?-catenin signaling pathway.
Ovarian Neoplasms
ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor.
Ovarian Neoplasms
The pattern of glycosyl- and sulfotransferase activities in cancer cell lines: a predictor of individual cancer-associated distinct carbohydrate structures for the structural identification of signature glycans.
Ovarian Neoplasms
The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype.
Pancreatic Neoplasms
Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells.
Pancreatic Neoplasms
Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death.
Pancreatic Neoplasms
The Glycosyltransferase ST6Gal-I Protects Tumor Cells against Serum Growth Factor Withdrawal by Enhancing Survival Signaling and Proliferative Potential.
Pancreatic Neoplasms
The ST6Gal-I sialyltransferase protects tumor cells against hypoxia by enhancing HIF-1? signaling.
Paraproteinemias
Sialyltransferase activity and sialic acid levels in multiple myeloma and monoclonal gammopathy.
Pneumococcal Infections
Elevated glycosyltransferase activities in infected or traumatized hosts: nonspecific response to inflammation.
Pneumonia
Recombinant Sialyltransferase Infusion Mitigates Infection-Driven Acute Lung Inflammation.
Pneumonia
Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice.
Polycythemia Vera
[Glycoprotein sialylation and NEU1 and ST6GAL1 expressions in erythremia].
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Elevated mRNA level of hST6Gal I and hST3Gal V positively correlates with the high risk of pediatric acute leukemia.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
The regulatory ZFAS1/miR-150/ST6GAL1 crosstalk modulates sialylation of EGFR via PI3K/Akt pathway in T-cell acute lymphoblastic leukemia.
Prostatic Neoplasms
Computer-aided design of human sialyltransferase inhibitors of hST8Sia III.
Prostatic Neoplasms
ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3?/?-catenin signaling pathway.
Retinitis Pigmentosa
[Sialyltransferase and galactosyltransferase of lymphocyte in retinitis pigmentosa]
Rhabdomyosarcoma
Monosialoganglioside biosynthesis by subcellular membranes of rhabdomyosarcoma cell lines differing in metastatic potential.
Scleroderma, Systemic
Investigation of sialic acids and sialyltransferase activity in blood of patients with systemic scleroderma.
Scleroderma, Systemic
Multiplex reverse transcription polymerase chain reaction assessment of sialyltransferase expression in peripheral blood mononuclear cells in systemic sclerosis.
Seizures
Differential expression of mRNAs for sialyltransferase isoenzymes induced in the hippocampus of mouse following kindled seizures.
Sinusitis
Reduced sialylation of glycoproteins in nasal glands of patients with chronic sinusitis.
Stomach Diseases
Characterization of ?2,3- and ?2,6-sialyltransferases from Helicobacter acinonychis.
Stomach Neoplasms
Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
Stomach Neoplasms
Diagnostic utility of glycosyltransferase mRNA expression in gastric cancer.
Stomach Neoplasms
Enhancement of metastatic ability by ectopic expression of ST6GalNAcI on a gastric cancer cell line in a mouse model.
Stomach Neoplasms
Modulation of glycosyltransferase ST6Gal-I in gastric cancer-derived organoids disrupts homeostatic epithelial cell turnover.
Stomach Neoplasms
RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells.
Stomach Neoplasms
[Significance of alpha 2,6-specific sialyltransferase ST6N and alpha 2,3-specific sialyltransferase ST3N in stomach carcinoma]
Teratocarcinoma
Inhibition of ganglioside sialyltransferase activity and stimulation of neutral glycolipid exocytosis by heparin.
Thrombasthenia
Glycoprotein-sialyltransferase activity of normal human, thrombasthenic and Bernard-Soulier platelets.
Thrombocytopenia
Role of sialic acid for platelet life span: exposure of beta-galactose results in the rapid clearance of platelets from the circulation by asialoglycoprotein receptor-expressing liver macrophages and hepatocytes.
Thrombocytopenia
Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands.
Trichinellosis
Increased sialylation as a phenomenon in accommodation of the parasitic nematode Trichinella spiralis (Owen, 1835) in skeletal muscle fibres.
Urinary Bladder Neoplasms
Development of Monoclonal Antibodies against CMP-N-Acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3Gal-I) Recombinant Protein Expressed in E. coli.
Urinary Bladder Neoplasms
Expression of sialyl-Tn sugar antigen in bladder cancer cells affects response to Bacillus Calmette Guérin (BCG) and to oxidative damage.
Urinary Bladder Neoplasms
Oxidative damage and response to Bacillus Calmette-Guérin in bladder cancer cells expressing sialyltransferase ST3GAL1.
Urinary Bladder Neoplasms
Sialyl Tn-expressing bladder cancer cells induce a tolerogenic phenotype in innate and adaptive immune cells.
Urinary Bladder Neoplasms
ST3Gal.I sialyltransferase relevance in bladder cancer tissues and cell lines.
Uterine Cervical Neoplasms
Knockdown of ST6Gal-I increases cisplatin sensitivity in cervical cancer cells.
Uterine Cervical Neoplasms
ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway.
Virus Diseases
Enzyme distributions in subcellular fractions of BHK cells infected with Semliki forest virus: evidence for a major fraction of sphingomyelin synthase in the trans-golgi network.
Virus Diseases
Inhibition of H5N1 highly pathogenic influenza virus by suppressing a specific sialyltransferase.
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