Reference on EC 2.4.1.133 - xylosylprotein 4-beta-galactosyltransferase and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Higuchi, T.; Tamura, S.; Takagaki, K.; Nakamura, T.; Morikawa, A.; Tanaka, K.; Tanaka, A.; Saito, Y.; Endo, M.
A method for determination of galactosyltransferase I activity synthesizing the proteoglycan linkage region
J. Biochem. Biophys. Methods
29
135-142
1994
Homo sapiens
Higuchi, T.; Tamura, S.; Tanaka, K.; Takagaki, K.; Saito, Y.; Endo, M.
Effects of ATP on regulation of galactosyltransferase-I activity responsible for synthesis of the linkage region between the core protein and glycosaminoglycan chains of proteoglycans
Biochem. Cell Biol.
79
159-164
2001
Homo sapiens
Okajima, T.; Yoshida, K.; Kondo, T.; Furukawa, K.
Human homolog of Caenorhabditis elegans sqv-3 gene is galactosyltransferase I involved in the biosynthesis of the glucosaminoglycan-protein linkage region of proteoglycans
J. Biol. Chem.
274
22915-22918
1999
Homo sapiens
Zhou, D.; Malissard, M.; Berger, E.G.; Hennet, T.
Secretion and purification of recombinant beta1-4 galactosyltransferase from insect cells using pFmel-protA, a novel transposition-based baculovirus transfer vector
Arch. Biochem. Biophys.
374
3-7
2000
Homo sapiens
Gulberti, S.; Lattard, V.; Fondeur, M.; Jacquinet, J.C.; Mulliert, G.; Netter, P.; Magdalou, J.; Ouzzine, M.; Fournel-Gigleux, S.
Phosphorylation and sulfation of oligosaccharide substrates critically influence the activity of human beta1,4-galactosyltransferase 7 (GalT-I) and beta1,3-glucuronosyltransferase I (GlcAT-I) involved in the biosynthesis of the glycosaminoglycan-protein linkage region of proteoglycans
J. Biol. Chem.
280
1417-1425
2005
Homo sapiens
Goette, M.; Kresse, H.
Defective glycosaminoglycan substitution of decorin in a patient with progeroid syndrome is a direct consequence of two point mutations in the galactosyltransferase I (beta4GalT-7) gene
Biochem. Genet.
43
65-77
2005
Homo sapiens
Seidler, D.G.; Faiyaz-Ul-Haque, M.; Hansen, U.; Yip, G.W.; Zaidi, S.H.; Teebi, A.S.; Kiesel, L.; Goette, M.
Defective glycosylation of decorin and biglycan, altered collagen structure, and abnormal phenotype of the skin fibroblasts of an Ehlers-Danlos syndrome patient carrying the novel Arg270Cys substitution in galactosyltransferase I (beta4GalT-7)
J. Mol. Med.
84
583-594
2006
Homo sapiens
Bakker, H.; Rouwendal, G.J.; Karnoup, A.S.; Florack, D.E.; Stoopen, G.M.; Helsper, J.P.; van Ree, R.; van Die, I.; Bosch, D.
An antibody produced in tobacco expressing a hybrid beta-1,4-galactosyltransferase is essentially devoid of plant carbohydrate epitopes
Proc. Natl. Acad. Sci. USA
103
7577-7582
2006
Homo sapiens (P15291), Homo sapiens
Goette, M.; Spillmann, D.; Yip, G.W.; Versteeg, E.; Echtermeyer, F.G.; van Kuppevelt, T.H.; Kiesel, L.
Changes in heparan sulfate are associated with delayed wound repair, altered cell migration, adhesion and contractility in the galactosyltransferase I (beta4GalT-7) deficient form of Ehlers-Danlos syndrome
Hum. Mol. Genet.
17
996-1009
2008
Homo sapiens
Daligault, F.; Rahuel-Clermont, S.; Gulberti, S.; Cung, M.T.; Branlant, G.; Netter, P.; Magdalou, J.; Lattard, V.
Thermodynamic insights into the structural basis governing the donor substrate recognition by human beta1,4-galactosyltransferase 7
Biochem. J.
418
605-614
2009
Homo sapiens (Q9UBV7), Homo sapiens
Wei, Y.; Liu, D.; Zhou, F.; Ge, Y.; Xu, J.; Yun, X.; Gu, J.; Jiang, J.
Identification of beta-1,4-galactosyltransferase I as a target gene of HBx-induced cell cycle progression of hepatoma cell
J. Hepatol.
49
1029-1037
2008
Homo sapiens (P15291)
Rahuel-Clermont, S.; Daligault, F.; Piet, M.H.; Gulberti, S.; Netter, P.; Branlant, G.; Magdalou, J.; Lattard, V.
Biochemical and thermodynamic characterization of mutated beta1,4-galactosyltransferase 7 involved in the progeroid form of the Ehlers-Danlos syndrome
Biochem. J.
432
303-311
2010
Homo sapiens
Talhaoui, I.; Bui, C.; Oriol, R.; Mulliert, G.; Gulberti, S.; Netter, P.; Coughtrie, M.W.; Ouzzine, M.; Fournel-Gigleux, S.
Identification of key functional residues in the active site of human {beta}1,4-galactosyltransferase 7: a major enzyme in the glycosaminoglycan synthesis pathway
J. Biol. Chem.
285
37342-37358
2010
Homo sapiens (Q9UBV7)
Pasek, M.; Boeggeman, E.; Ramakrishnan, B.; Qasba, P.K.
Galectin-1 as a fusion partner for the production of soluble and folded human beta-1,4-galactosyltransferase-T7 in E. coli
Biochem. Biophys. Res. Commun.
394
679-684
2010
Homo sapiens
Bui, C.; Talhaoui, I.; Chabel, M.; Mulliert, G.; Coughtrie, M.W.; Ouzzine, M.; Fournel-Gigleux, S.
Molecular characterization of beta1,4-galactosyltransferase 7 genetic mutations linked to the progeroid form of Ehlers-Danlos syndrome (EDS)
FEBS Lett.
584
3962-3968
2010
Homo sapiens
Garcia-Garcia, J.F.; Corrales, G.; Casas, J.; Fernandez-Mayoralas, A.; Garcia-Junceda, E.
Synthesis and evaluation of xylopyranoside derivatives as decoy acceptors of human beta-1,4-galactosyltransferase 7
Mol. Biosyst.
7
1312-1321
2011
Homo sapiens
Gu, J.; Fan, J.; Xu, Y.; Xie, Y.; Gong, T.; Kong, Y.
Regulatory function of beta1,4-galactosyltransferase I expression on Lewis-Y glycan and embryo implantation
Gene
562
220-225
2015
Homo sapiens (P15291)
Tsutsui, Y.; Ramakrishnan, B.; Qasba, P.K.
Crystal structures of beta-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding
J. Biol. Chem.
288
31963-31970
2013
Drosophila melanogaster (Q9VBZ9), Homo sapiens (Q9UBV7)
Saliba, M.; Ramalanjaona, N.; Gulberti, S.; Bertin-Jung, I.; Thomas, A.; Dahbi, S.; Lopin-Bon, C.; Jacquinet, J.C.; Breton, C.; Ouzzine, M.; Fournel-Gigleux, S.
Probing the acceptor active site organization of the human recombinant beta1,4-galactosyltransferase 7 and design of xyloside-based inhibitors
J. Biol. Chem.
290
7658-7670
2015
Homo sapiens (Q9UBV7)
Siegbahn, A.; Thorsheim, K.; Stahle, J.; Manner, S.; Hamark, C.; Persson, A.; Tykesson, E.; Mani, K.; Westergren-Thorsson, G.; Widmalm, G.; Ellervik, U.
Exploration of the active site of beta4GalT7: modifications of the aglycon of aromatic xylosides
Org. Biomol. Chem.
13
3351-3362
2015
Homo sapiens (Q9UBV7)
Thorsheim, K.; Willen, D.; Tykesson, E.; Stahle, J.; Praly, J.P.; Vidal, S.; Johnson, M.T.; Widmalm, G.; Manner, S.; Ellervik, U.
Naphthyl thio- and carba-xylopyranosides for exploration of the active site of beta-1,4-galactosyltransferase 7 (beta4GalT7)
Chemistry
23
18057-18065
2017
Homo sapiens (Q9UBV7)
