Reference on EC 1.5.3.13 - N1-acetylpolyamine oxidase and Organism(s) Homo sapiens
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Vujcic, S.; Liang, P.; Diegelman, P.; Kramer, D.L.; Porter, C.W.
Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion
Biochem. J.
370
19-28
2003
Homo sapiens (Q6QHF9), Homo sapiens
Wang, Y.; Hacker, A.; Murray-Stewart, T.; Frydman, B.; Valasinas, A.; Fraser, A.V.; Woster, P.M.; Casero Jr, R.A.
Properties of recombinant human N1-acetylpolyamine oxidase (hPAO): potential role in determining drug sensitivity
Cancer Chemother. Pharmacol.
56
83-90
2005
Homo sapiens (Q6QHF9), Homo sapiens
Jaervinen, A.; Keinaenen, T.A.; Grigorenko, N.A.; Khomutov, A.R.; Uimari, A.; Vepsaelaeinen, J.; Naervaenen, A.; Alhonen, L.; Jaenne, J.
Guide molecule-driven stereospecific degradation of alpha-methylpolyamines by polyamine oxidase
J. Biol. Chem.
281
4589-4595
2006
Homo sapiens
Järvinen, A.; Grigorenko, N.; Khomutov, A.R.; Hyvönen, M.T.; Uimari, A.; Vepsäläinen, J.; Sinervirta, R.; Keinänen, T.A.; Vujcic, S.; Alhonen, L.; Porter, C.W.; Jänne, J.
Metabolic stability of alpha-methylated polyamine derivatives and their use as substitutes for the natural polyamines.
J. Biol. Chem.
280
6595-6601
2005
Homo sapiens
Basu, H.S.; Thompson, T.A.; Church, D.R.; Clower, C.C.; Mehraein-Ghomi, F.; Amlong, C.A.; Martin, C.T.; Woster, P.M.; Lindstrom, M.J.; Wilding, G.
A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model
Cancer Res.
69
7689-7695
2009
Homo sapiens
Han, Y.; Ren, Y.S.; Cao, C.Y.; Ren, D.M.; Zhou, Y.Q.; Wang, Y.L.
Highly expressed N1-acetylpolyamine oxidase detoxifies polyamine analogue N1-cyclopropylmethyl-N11-ethylnorspermine in human lung cancer cell line A549
Chin. Med. Sci.
122
1394-1399
2009
Homo sapiens
Häkkinen, M.; Hyönen, M.; Auriola, S.; Casero Jr., R.; Vepsäläinen, J.; Khomutov, A.; Alhonen, L.; Keinänen, T.
Metabolism of N-alkylated spermine analogues by polyamine and spermine oxidases
Amino Acids
38
369-381
2010
Homo sapiens
Moriya, S.; Iwasaki, K.; Samejima, K.; Takao, K.; Kohda, K.; Hiramatsu, K.; Kawakita, M.
A mass spectrometric method to determine activities of enzymes involved in polyamine catabolism
Anal. Chim. Acta
748
45-52
2012
Homo sapiens
Moriya, S.S.; Miura, T.; Takao, K.; Sugita, Y.; Samejima, K.; Hiramatsu, K.; Kawakita, M.
Development of irreversible inactivators of spermine oxidase and N1-acetylpolyamine oxidase
Biol. Pharm. Bull.
37
475-480
2014
Homo sapiens
Keinaenen, T.A.; Grigorenko, N.; Khomutov, A.R.; Huang, Q.; Uimari, A.; Alhonen, L.; Hyvoenen, M.T.; Vepsaelaeinen, J.
Controlling the regioselectivity and stereospecificity of FAD-dependent polyamine oxidases with the use of amine-attached guide molecules as conformational modulators
Biosci. Rep.
38
BSR20180527
2018
Homo sapiens (Q6QHF9), Homo sapiens
Khomutov, M.; Hyvonen, M.; Simonian, A.; Weisell, J.; Vepsalainen, J.; Alhonen, L.; Kochetkov, S.; Keinanen, T.; Khomutov, A.
Acetylated derivatives of C-methylated analogues of spermidine synthesis and interaction with N1-acetylpolyamine oxidase
Mendeleev Commun.
28
479-481
2018
Homo sapiens (Q6QHF9)
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