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2.7.1.B26: aminoglycoside 3'-phosphotransferase

This is an abbreviated version!
For detailed information about aminoglycoside 3'-phosphotransferase, go to the full flat file.

Word Map on EC 2.7.1.B26

Reaction

GTP
+
gentamicin JI-20A
=
GDP
+
gentamicin JI-20A 3'-phosphate

Synonyms

aminoglycoside 3'-phosphotransferase VIII, APH(3'), APH-3'-IIIa, Aph3, APHVIII, biosynthetic aminoglycoside 3'-phosphotransferase, GnTI

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.B26 aminoglycoside 3'-phosphotransferase

Inhibitors

Inhibitors on EC 2.7.1.B26 - aminoglycoside 3'-phosphotransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide
10 mM, 2% residual activity
4-chloromercuribenzoic acid
0.5 mM, 3% residual activity
diethyldicarbonate
2.5 mM, 10% residual activity
N-ethylmaleimide
0.5 mM, 47% residual activity
Phenylglyoxal
2.5 mM, 10% residual activity
Tetranitromethane
2.5 mM, 23% residual activity