2.7.1.157: N-acetylgalactosamine kinase

This is an abbreviated version!
For detailed information about N-acetylgalactosamine kinase, go to the full flat file.

Word Map on EC 2.7.1.157

2.7.1.157

galactokinase

galactose

nalidixic

antimutator

proofreading

gale

papillation

mgatp

udp-galnac

udp-galactose

synthesis

Reaction

N-acetyl-alpha-D-galactosamine 1-phosphate

Synonyms

GALK2, GalNAc kinase, GalNAcK, GK2, More, N-acetylgalactosamine (GalNAc)-1-phosphate kinase

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.157 N-acetylgalactosamine kinase

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Results	in table
50	AA Sequence
1	Application
1	CAS Registry Number
6	Cloned(Commentary)
2	Cofactor
1	Crystallization (Commentary)
7	Disease/ Diagnostics
3	Inhibitors
1	Ki Value [mM]
56	KM Value [mM]
3	Localization
5	Metals/Ions
3	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
11	Organism
2	Pathway
2	pH Optimum
4	pH Range
7	Protein Variants
4	Purification (Commentary)
3	Reaction
1	Reaction Type
11	Reference
10	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
21	Substrates and Products (Substrate)
3	Subunits
18	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
27	Turnover Number [1/s]

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Reference on EC 2.7.1.157 - N-acetylgalactosamine kinase

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659129

Pastuszak, I.; Drake, R.; Elbein, A.D.

Kidney N-acetylgalactosamine (GalNAc)-1-phosphate kinase, a new pathway of GalNAc activation

J. Biol. Chem.

271

20776-20782

1996

Oryctolagus cuniculus, Homo sapiens, Sus scrofa

8702831

659130

Pastuszak, I.; O'Donnell, J.; Elbein, A.D.

Identification of the GalNAc kinase amino acid sequence

J. Biol. Chem.

271

23653-23656

1996

Homo sapiens, Sus scrofa

8798585

659494

Thoden, J.B.; Holden, H.M.

The molecular architecture of human N-acetylgalactosamine kinase

J. Biol. Chem.

280

32784-32791

2005

Homo sapiens

16006554

672583

Bourgeaux, V.; Piller, F.; Piller, V.

Two-step enzymatic synthesis of UDP-N-acetylgalactosamine

Bioorg. Med. Chem. Lett.

5459-5462

2005

Homo sapiens

16203137

704525

Stockbridge, R.B.; Wolfenden, R.

The intrinsic reactivity of ATP and the catalytic proficiencies of kinases acting on glucose, N-acetylgalactosamine, and homoserine: a thermodynamic analysis

J. Biol. Chem.

284

22747-22757

2009

Homo sapiens

19531469

709300

Agnew, A.; Timson, D.

Mechanistic studies on human N-acetylgalactosamine kinase

J. Enzyme Inhib. Med. Chem.

370-376

2009

Homo sapiens, Homo sapiens (Q01415)

19874134

721309

Kristiansson, H.; Timson, D.J.

N-acetylgalactosamine kinase: a naturally promiscuous small molecule kinase

Appl. Biochem. Biotechnol.

166

57-63

2012

Homo sapiens (Q01415), Homo sapiens

21984386