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2.1.1.4: acetylserotonin O-methyltransferase

This is an abbreviated version!
For detailed information about acetylserotonin O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.4

Reaction

S-adenosyl-L-methionine
+
N-acetylserotonin
=
S-adenosyl-L-homocysteine
 +
Melatonin

Synonyms

acetylserotonin methyltransferase, ASMT, ASMT1, ASMT2, COMT, HIOMT, hydroxindole-O-methyltransferase, hydroxyindole methyltransferase, hydroxyindole O-methyltransferase, hydroxyindole-O-methyl transferase, hydroxyindole-O-methyltransferase, MANES_17G050500, methyltransferase, acetylserotonin, N-acetylserotonin methyltransferase, N-acetylserotonin methyltransferase1, N-acetylserotonin O-methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.4 acetylserotonin O-methyltransferase

Source Tissue

Source Tissue on EC 2.1.1.4 - acetylserotonin O-methyltransferase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
dorsal portion
Manually annotated by BRENDA team
-
fertile egg yolk
Manually annotated by BRENDA team
-
postovulatory, no activity in preovulatory ovarian follicle
Manually annotated by BRENDA team
-
CD19+ cell, CD14-CD4+ cell, CD56-CD8+ cell, CD56+ cell
Manually annotated by BRENDA team
-
lowest activity in spleen
Manually annotated by BRENDA team
-
mucosa from the ulcer margin
Manually annotated by BRENDA team
the testes of control animals express the Tph1, Aanat, and Asmt and Per2 genes with 24-h rhythms in mRNA, reaching the maximal values during the dark phase. Pinealectomy abolishes and melatonin treatment restores the 24-h rhythmicity
Manually annotated by BRENDA team
additional information