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2.1.1.223: tRNA1Val (adenine37-N6)-methyltransferase

This is an abbreviated version!
For detailed information about tRNA1Val (adenine37-N6)-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
adenine37 in tRNA1Val
=
S-adenosyl-L-homocysteine
+
N6-methyladenine37 in tRNA1Val

Synonyms

YfiC

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.223 tRNA1Val (adenine37-N6)-methyltransferase

General Information

General Information on EC 2.1.1.223 - tRNA1Val (adenine37-N6)-methyltransferase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
inactivation of yfiC gene abolishes m6A formation in tRNA1(Val), while expression of the yfiC gene from a plasmid restores the modification
physiological function
the methylation of m6A in tRNA1(Val) by YfiC has little influence on the cell growth under standard conditions, the yfiC gene confers a growth advantage under conditions of osmotic and oxidative stress