1.1.1.11: D-arabinitol 4-dehydrogenase
This is an abbreviated version!
For detailed information about D-arabinitol 4-dehydrogenase, go to the full flat file.
Reaction
Synonyms
aArDH, arabitol dehydrogenase, ArDH, D-arabitol dehydrogenase, D-xylulose-forming D-arabitol dehydrogenase, dehydrogenase, D-arabinitol, NAD-dependent D-arabitol dehydrogenase
ECTree
Advanced search results
General Information
General Information on EC 1.1.1.11 - D-arabinitol 4-dehydrogenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
evolution
Gluconobacter sp. JX-05
enzyme ArDH containing a NAD(P)-binding motif TGXXX[AG]XG and a classical active site motif belongs to the short-chain dehydrogenase family
additional information
Gluconobacter sp. JX-05
ArDH has a conserved sequence region of TGXXXGXG, in this NAD(P)-binding motif, glycine-rich region plays a critical role in the stability of this kind of domain. Conserved domain of YXXXK, a classical active site motif, accompanying with two conserved amino acids N119 and S147 in the upstream, is also found in ArDH, sequence comparisons. Structure-function analysis of ArDH, and structure homology modeling using the structure of putative polyol dehydrogenase (PDB ID 3AWD) from Gluconobacter oxydans strain DSM2343 as template, overview