>H9N289|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas putida|Swiss-Prot
MEQAIINDEREYLRHFWHPVCTVTELEKAHPSSLGPLAVKLLNEQLVVAKLGDEYVAMRD
RCAHRSAKLSLGTVSGNRLQCPYHGWQYDTHGACQLVPACPNSPIPNKAKVDRFDCEERY
GLIWIRLDSSFDCTEIPYFSAANDPRLRIVIQEPYWWDATAERRWENFTDFSHFAFIHPG
TLFDPNNAEPPIVPMDRFNGQFRFVYDTPEDMAVPNQAPIGSFSYTCSMPFAINLEVSKY
SSSSLHVLFNVSCPVDSHTTKNFLIFAREQSDDSDYLHIAFNDLVFAEDKPVIESQWPKD
APADEVSVVADKVSIQYRKWLRELKEAHKEGSQAFRSALLDPVIESDRSYI
>A0A150HQ23|methylxanthine N1-demethylase|EC 1.14.13.178|Acinetobacter venetianus|TrEMBL
MPYWEHADFQQLVCPSVDLNCFAGRQLEGFIDVAHFAWVHPDTFGDPENVEVPDYTTTET
TYGFEADYISSVGRYPIGTDQRGKDGFQWLRHFEISLPFTATLTIHFPNETKQVIMNAAS
PVSARQTRLFAPICRNYDKDLPIEDAYKFNLEIFEEDRLIVETQKPEYLPLDLSMEAHFP
ADRSSSMYRKLLRKMGFSPIFAA
>A0A1Y0N7M4|methylxanthine N1-demethylase|EC 1.14.13.178|Curvibacter sp. AEP1-3|TrEMBL
MRLESRPLKEHSLWLPVMASTSLTDAPLAITLLEQELVLWRDATGSAHAWADQCPHRGAK
LSLGRVCAGRLECPYHGWQFEAGGQCVHVPAVPSFVPPASHAARTHPVVEAYGLLWVQLQ
PEAGVPLPAFVAESDTQLRKVLCGPYDVATSAPRIVENFLDMAHFGFVHEGWLGMREATA
IDDYCVELTPTGLLATQCRAWQPQSNVHSTAPAQVEYTYEVVAPYTAVLTKVPDAASVAL
QGFRESIALFICPTTPETSRVWFRLAMADFDSPDNKLQDFQHTIFMQDKPVLESQRPRRL
PLDVRAEVHTTADKASSAYRRFLKQETITFGVC
>A0A2S6TW62|methylxanthine N1-demethylase|EC 1.14.13.178|Alphaproteobacteria bacterium MarineAlpha4_Bin2|TrEMBL
MINDLVLINDWYIVAAARDLNDVTPLAVRLWDEELVVWRSGDEVIAWRDYCVHRGAKLSP
GEVKEGTLVCPYHGWRYGPSGACTLIPAHPEIQPPAKARALAYKAVESDGYIWVSLGEPK
REPANFPEFSNEDYRKLLVGPYNYHGNPFRTVENFLDVAHFPFVHANINGDPDAPEPIGE
YEVFRDDGGLRTGPIPRFQPFGDHRGIPVTAHYKYNCPRPLSAYFSKDTGEGHRFCTFMA
VTPLAENDCLLWVQIAINYGHDLSEPQILERQDAVYNQDKPIIESQRPHPL
>A0A679IXM9|methylxanthine N1-demethylase|EC 1.14.13.178|Methylobacterium bullatum|TrEMBL
MAGDEIASGQSRPIMLSSPPPQAKADTAKNPATDDAALDPDAMRQPLPDAFYCVGRSDTL
KPGSLRAVELNGEQIVLGRDKAGAAFAMRDRCPHRGMALSKGRFDGEAVTCPFHGWRFGT
DGRCRDVPTLSSADAADFTRIAVQRFPIRESAGFVWVNPSLGPPGGDLPPLPELGFEAAG
SLVVELVVEASFDLTTLSLVDPGHVAFVHDSWWFRPSKELREKVKTFTPTPHGFTMSSHA
TTTSSPVYKLLGGVPEVEIEFRLPGVRLERIEAGPKRVANYTFATPLTHNRTMLTNALYW
NIPVLNLLKPLARPLMRQFLTQDQQVLQHAQAGLDRKPTMVLFGQSDLPSQWYFRLKREA
LQAAREARSFRNPLVQQELRWRS
>A0A517XZL9|methylxanthine N1-demethylase|EC 1.14.13.178|Urbifossiella limnaea|TrEMBL
MGMLDHWQPVLRSAELRAKPVGVTVAGEPIAVFRTAAGLGALADACPHRKLKLSIGTVVG
EKLRCQYHGWTFDACGSGESPGSPKLHACTTSYDVREEHGLVWLKSRQSRPEFPRLAPDG
FHPVCTLSHVLPAPLELAVDNFTEIEHSGTVHTTFGYDLERMNEVKVRFESTASSVRVIN
EGPTKRLNPVFAWFLGIKPGDTFHDDWTTYFSPLYSVYDHWWTSPDGSREGMVRWRLYLF
FVPIDDRSTRLFSVTYAKSRYPGPMGGLRLVRRLFAREIDREVTADVNMLHHLADYDTGI
AGLKLSRFDKVLGLTRERIGTIYRGESPRTLRLVA
>A0A399FDJ8|methylxanthine N1-demethylase|EC 1.14.13.178|Meiothermus granaticius NBRC 107808|TrEMBL
MSEILRQHWLPLALAAEVRTKGLYPVRLLGEEAVLVGLESGIELWQDLCIHRGTKLSLGR
LEREQVICPYHGWVYERGGRCVRFPAHAQQTPPAKATARVYAAREQYGMVWGALEPPVAD
IPPFYEWGQPGFKTVMCGPYAFRASAPRVVENFLDVAHFPFVHEGLLGDQAHPEIPDYEV
EEKEGRIRAKDIRVYQPNPDGTGVGRYVSYTYEVLAPLSAYFTKRDESGRVFSIFMSVTP
VSELESLGWFYVAMNYGDQSPEEIRAFQDRVAMQDVPIVESQRPERLPLDLQAELHLRSD
RVAIAYRSLLRRLGVGFGTA
>A0A1E3HA05|methylxanthine N1-demethylase|EC 1.14.13.178|Methylobrevis pamukkalensis|TrEMBL
MHIPSLAPGAPIPEKARAIAYKAREAYGLVWVCLAEPAMPFPEWPDDAWNRPDHRVILVN
TYDWKASAGRVVENAMDFSHFNFVHLGYTELADGPVIKPYEVTKTERGLNYAYDDGHLLR
DYVIEFPFIVHDRKSVVKVGNVKTWSDNEESKPGDITCLSFLSAPIDDTFTRIYVFVGRN
HSLDKADAQFTGGFDTVMEQDRVIVETQRPEQIPVSISEELHIRFPDAGAVQYRRMLRDL
DKAEAFVP
>A0A0P0MES3|methylxanthine N1-demethylase|EC 1.14.13.178|Limnohabitans sp. 103DPR2|TrEMBL
MLVTQQAIFRKYWHAVMPLSELASGPKPFTLLGEKIVLFLDAQGQPAALADRCCHRTAKL
SKGQCKNGNLECAYHGWQYNSVGKVVVIPQYAADREIPSDYRTQAFHCVARYGYAWVALE
DPIADIFEVPEFDNPQYRTIFQFYETWATSPVRALENSFDNAHFSFVHKATFGVAASPKP
SKYELHESEIGFEAETVIEAVNPEKFQRISGVQDPITTRHMRNAYYLPFSRRLDIEYPSG
IRHIIINCFTPIDDGHIQLCQWLFRNDTEADCPAEMLIHFDEVITREDKDILESTDHDAV
VDMRRRGVEFSMDSDRPGILIRKKLMELLAKHGEVEVHR
>A0A2U3N2J2|methylxanthine N1-demethylase|EC 1.14.13.178|Acinetobacter stercoris|TrEMBL
MNAIPVLNLVTQPNCSEFDPSDWNILAEHWYPVARIQDVTEQPQQVQLLDVKMALYKTES
GEIQLARDICPHRGVPLSKGWVEGDEIICPYHGLRYNTAGKCVKIPAQPELTKISDRFSL
IKFPVILKYGLVWTSLSGRDENKANFPVLDTWDNEQHQAILPPFVDIGGASGRQLEGFID
VAHFAWVHHQSFANPENPVVPKYSTERTDYGLHTEYVSDVSNYPHGMQHLAPAGFLWKRI
FDVYPPFSAVLTIHFPENGILKILNACCPVSHNKTRLFVPLTRNFDTTGDLEAVYSFNAQ
IFAEDQEMVESQKPEELPLDISMEAHFEADRSSTTYRRILAEWGLSKRYII
>A0A177H7V9|methylxanthine N1-demethylase|EC 1.14.13.178|Rhodobacteraceae bacterium SB2|TrEMBL
MEPILELTEPHAIALCDSIQTGGVHPIQLQDVELVLWRDYAGQAHVWHDRCPHRGMRLSF
GFVKENRLTCLYHGWEYGSDGGCRKIPAHPEVTPPKTLCADILNVSECYGMVFVSAGKNT
AKPNTEWVSVRSIFLECDRAQALVEIAEFVEIAEAQENQVYLNKSNTVAVAVQTCSRKSC
AIHLSTRSTDPTERLALAKRMVALRRKINQGLRA
>A0A1D8ATT3|methylxanthine N1-demethylase|EC 1.14.13.178|Lacunisphaera limnophila|TrEMBL
MTPPRNCTFPATDWTVLARCWHAVALSADVTATAPFAARLLDQDLVLYRTATGLTVAADL
CVHRGAPLSLGCMQEGAIACAYHGYRYDGTGRCTLIPAHPNAPIPGKLALRVFPARERHG
LVWVSLDPGAQPDTVPDFPEHVDPAFQIVTVPPFDWDASAGRQVESFCDVAHFTFVHPTT
FAASDPVVPRYEVEATPRGVRAEFASRVGNVSDPAAAQQTWRRIYQLHLPFTAHLSVDFP
AGGRLVVFNAACPVSARRTRVFAVVARNFDRDQPVADLIAFQQKVYAEDQRIVERQNPED
LPIDLGEEVHVKADRTSVEYRRQLARLGLGRGFTA
>A0A2S9YGI6|methylxanthine N1-demethylase|EC 1.14.13.178|Enhygromyxa salina|TrEMBL
MDGPSSTGSEGEGRPRLPIVGSGNSSAARVLDDWFVVCSSDELDALGAKPLSTTLYGVPI
VVFRGATGEVGALLDRCPHRNVPLSDGAVEGALLRCGYHGWAFDAEGVCREIPTLCGDPE
GKARVVPRFAACEQDGVVWVYATPDVEPVREPYVFRWVRDSRYHSGRETFEVDGTIHAVA
ENALDVPHTAFLHKGLFRKSGAGNRIEVVVRRWHDRAEAEYIGEPRPPGVVGRLLAPQGG
VVEHFDRFVLPSITEVEYRLGETSHICTVSALTPITDTRTRLTAVISFRLPVPSFMVTPV
LGPLARAIFKQDAAVLERQVANIERFGGESFVSTEVDALGPQILRLLRNAERGDRGAPGE
RGEPGVEPAHEHRFFMEV
>A0A0D1EHA7|methylxanthine N1-demethylase|EC 1.14.13.178|Jannaschia aquimarina|TrEMBL
MAFSHDLKSKPLGIAVDDVPVVLWRAEGAVQALVDQCPHRSAKLSVGKVVEGGAIQCPFH
AWRFGGDGVCRSIPLVTGAERPAKVRAGRLAAREAGGLIWLFTRVLEVDEAVPPMPSLPP
SMTEPGWHGDMIVREWDAHWSRAIQTMLDVAHIPFVRARTIGAGLGRKIGKVDAAHLKLD
LRETGGGAYEMDWGLTDPVTGGESDAGWLAFLPPNGMSPKVPVKGETKQGGARVPKEWYL
HIFCTPTTEGRSNQFVVPRRNFGRGNPAWAAADKLNIVVLNEDKRNVETAWPSRVPAPTA
EISMPADASTIAFQRYHWKTFVEPTLPPRGADAVEAAE
>A0A3P5X9G6|methylxanthine N1-demethylase|EC 1.14.13.178|Xinfangfangia humi|TrEMBL
MLDMLRPYWYPVAPLGALGDGPTRLKLLGEQLVLWKGPEGRPVAMKDLCIHRGAALSGGT
IENGEIKCPYHGWKYSASGACTHIPALPPGAPIPAKARAITYPTRAAYGMVWICLGDGST
PFPDFLSDYEDEAIWRQVYVDHYDWKTSAGRVVENAMDFSHFNFVHMGYTELADGPIIKP
YEVERNERGFTYAYDDGHLLREYVVEFPFIVHDRKRVTNPAGGKTWSDSGEGSSGDVTLL
SFFATPVDENETRIHVMVTRNHSLDRADSEFTGGFGVVMGQDQVIVETQRPEQIPMDVSE
ELHIRLPDQHAILYRRMLRELNLPAAYMP
>A0A1V5P5F8|methylxanthine N1-demethylase|EC 1.14.13.178|Chloroflexi bacterium ADurb.Bin360|TrEMBL
MIPNQWYVVLDSKQVGAKPIGVTRMDEKLVFWRDAAGKVSCLRDLCAHRGVALSKGKVIE
GALQCPFHGFAYDTSGAAVVIPANGKKAAIPARFKVHAYPTYEAHGFIWIWWGQTPPPDL
QPPSFFEDITPDFSYGSARDPWEAHYSRVIENQLDVVHLPFVHHNTIGRGNRALVNGPVV
EWQEANRFRVYVFNEADRGQSPRKPEEIAPPYPEFHLEFQFPNLWQNHISQDVRVVAAFV
PVDGEHTLLYLRFYQRFMRLPVLRNLINALSMPFNVLVAHQDRRVVITQQPKPSALRSAE
NLIQGDRPIVEYRRRREALRQAAVAIDHPVA
>A0A1Y5TT33|methylxanthine N1-demethylase|EC 1.14.13.178|Roseisalinus antarcticus|TrEMBL
MLDVLRKYWNPVARSEEITPTPTRHMMLGEQLVLWRTSDSGTVSVMKDLCIHRGAALSGG
RVEGENIVCPYHGWRYGADGACTHIPSLPEGSPIPAKARTTTYPVREAYGLIWVAQDDDP
APFPDFLDAYESDPAFRMCYVSHYDWATSAGRVLENAMDFSHFNFVHKGYTELADGPVIK
PYEVKRSDRGFTYAYDDGHLVRDYTVEFPFIVHDRKSVTNPEGGKTWSDDGESKAGDCTL
LTFIAAPVDEATTRIHVLVSRNHGLNRPDEDFTSGFDVVMNQDKVIVESQRPEQIPMDLK
EELHLRMPDAHAVLYRRMLREIDLPEGYMP
>A0A1A6DTL4|methylxanthine N1-demethylase|EC 1.14.13.178|Tepidimonas fonticaldi|TrEMBL
MVERDHWWPVALADDVGAAPVPVTLLDEPLVLWRDGAGAVQAFADRCPHRGARLSLGAVV
EGQLRCPYHGWRFDGDGRCRAIPALPGFAPPDGHAACRHAVAQAHGLLWVCLGTPVAPAP
PSLPPLPPRRVVHGPFDVATSAPRAIENFLDTAHFAYVHEGWLGAPTHAEVPPYEVTLTA
DGRPVVPDYPAWQPRATARAQGGAWVRYRYEVLSPYAALLQKQPEGDAPADAYVMWACPT
TPETCRVWFVQHTTDTTTPDAALREFQSAIFAQDRPILESQTPKRLPLFGGEAMCAADRL
SAAYRRYLRAAGITFGVC
>A0A554XBI9|methylxanthine N1-demethylase|EC 1.14.13.178|Tepidimonas taiwanensis|TrEMBL
MIERGHWWPVALATDVGEAPLPVTLLGEPLVLWRDAAGAVQAFADRCPHRGARLSLGVVV
EGQLQCPYHGWRFDGQGQCRRVPALPGFTPPADHRAVRYAVTAAHGLLWVCLGEPVTDGP
PPLPALPTRCVLHGPFDVATSAPRAVENFLDTAHFAFVHAGWLGDPAHGEVPHHTLVHTP
DGRPVVPDYPAWQPRASASAAGGAWVRYRYEVLSPYAALLHKRPAGEGPTDAYVLWASPQ
QPEACRVWFAQYTSDTDTPDEVLRAFQSTIFAQDRPILESQSPKRLPLDGSERMCAADRL
SAAYRRYLREQGITFGVC
>A0A2M9NDQ5|methylxanthine N1-demethylase|EC 1.14.13.178|Paenibacillus sp. GM1FR|TrEMBL
MITYNANHTMTSELPRGCTFTAEDWHVLSQYWYPVAQATEVTDKPLAAQLLDVKLVLYRS
NDQVVVAKDLCFHRGAPLSKGWVENGEIVCPYHGFRYNCEGKCTAVPAHPSSNISPKLKL
IVYPAVERFGLIWTTLAGTEEQIPSFPGWDDPDYINILPPNFDIAGSSGRQMEGFLDVSH
FAYVHTETFGDRNNTEVPQYKVKREGNELLAEYWSTVSNYGKGQDLVAPEGFQWLREFRV
FPPFAASLTVHFPGDDKLNILNCASPISARYTRLFCPITRNFDKDAPIEDTIKFNLQVFE
EDREMVESQKPEDLPLDLHAEAHIPADRTSIAYRQLLTELGLGRNYTS
>A0A2P4UEN0|methylxanthine N1-demethylase|EC 1.14.13.178|Actinomadura rubteroloni|TrEMBL
MNTTTTTAPGAAAPITNEHPSLGRAWLPVALSGEITARPARVLLLGEPWVVVRMDGTLFA
ARDRCPHRLAPLSIGAVVDGTLQCKYHGWRYGTDGRCVEVPSAGPDARIPSRAVLDRPFG
VREHLGLVWIAPREPVLDLPGLPGWDTPGIDRIFAEPRRTTASAAQLVDNFVDISHFATV
HTGTFGTPESAQIAPSDVTRQAWTANTRYTTYYRNTDDPLTATGEHPEIQPHVVEKTAFA
PSVVAMCLTFPLTDQVFEILYALQPESATSTRIYKVMTRNDFHGDAGRIKAMLDFEDAVL
DEDLFVLESFDRAELNLDARVELHTRADRMSLAYRKLLGRLVELDAGPRSTPSA
>A0A554W6N2|methylxanthine N1-demethylase|EC 1.14.13.178|Tepidimonas alkaliphilus|TrEMBL
MVERDHWWPVALDGDVGAAPLPVTLLGEPLVLWRDGAGAVQAFADRCPHRGARLSLGAVV
GGQLQCPYHGWRFDGDGRCRAIPALPGFAPSASHAACRHAVVPAHGLLWVCLGTPAAPAP
PALPPLPPRRVVHGPFDVATSAPRAIENFLDTAHFAYVHDGWLGAPTHAEVPPYEVTPTA
DGRPVVPDYPAWQPRATASAQGGAWVRYRYEVLSPFAALLQKQPEGDAPADAYLMWACPT
TPETCRVWFVQHTTDTTTPDEALRDFQSAIFAQDRPILESQTPKRLPLCGGEAMCAADRL
SAAYRRYLRTAGITFGVC
>A0A5E6MHM9|methylxanthine N1-demethylase|EC 1.14.13.178|Methylacidimicrobium tartarophylax|TrEMBL
MRDPLLDEWHPIAASEELPEGGALPASLLGQEIVLWRGDRGVHAWPDLCLHRGARLSRGK
VARNCLRCPYHGWTYSEEGQCIAIPAHPGVHPPQRAHLLPFPARERYGMVWISLGCPSGD
PPPFPEWEDGSLAKTRCGPYRVNASAPRLLENFLDVAHLPIAHEGILGDPSRPEIPAYRV
ERRPEGGWIAADIPVWQPDPDGSSRAQTVTYTYEILRPLAARFRKTGEGKRYGILAAVHP
IGLRESAFWMWNFWDPQQGVRPEEIRAHQERIFAQDRPIVESQRPELLPLDLQAELHLPS
DRLAIAYRRWLAELGVGFGTG
>A0A5A5RSZ2|methylxanthine N1-demethylase|EC 1.14.13.178|Microcystis aeruginosa NIES-2521|TrEMBL
MTSADQSQPLPRDDYFHYQNCWYPVLFVQDWQKNPYSFSLYGQPLLIFRDQQGKWGCLLD
CCPHRLAKLSTGQMIAGRLECLYHGWQFETDGKCSHIPQLPVNAPIPRNAKVKSYGVVER
QGVLWVWLGEEETAKESDIPIIKDLEDPNCVHTDYLIDFPYEQGYLLENLLDPAHVNISH
DRSEFGAKRENAQPLAFQILEISARGIRSQWRNSHNPQESWKYLDFIAPNLVHYRFSLPN
PDWCAGLALYGISLGQGRSRLLMRRYQNFAVNSRQYRWRWLEHLRQSRILEDDLPLIQSQ
QQMVEKSRDSLQKLYLPLKSSDALVIELRQWFDRYGDSFPYYQGYTSQRTTAIDLSDPLP
LDRYSRHTVHCRTCSDAHENMVKTKQIAILMGILLVLLAILSPNQSIYQVTALIFAILAL
AVAIAANYTRTKFERTYEKKAHTKLQ
>A0A1C9WAT1|methylxanthine N1-demethylase|EC 1.14.13.178|Microbulbifer aggregans|TrEMBL
MLTNLWYVAEWSKAVKDKPVRVKLLGQNFVLFRDKAGKVNCLSDVCIHRGGSLSKGWTTD
RNCVACPYHGWEFDAEGKVQFIPSRGEGAPIPERARIDAYPTEERYGMIWVFLGDLPEEE
RYPIPEFPEYDDKANWRAVEVDYNWTGSVDRVVENGIDIAHTAFVHPGFGYQEMADKNEI
LKVDRGEYWGSSDNVLYPPQLEGNFGLMKLFRADKAATYVTPAFYLPGHCVRLHIKVNSW
MEMIIFDANTPIDENTTRSFAVQVRNFFKWPIFDNGAKKRTKKVFGEDGDIVAELSPNYL
PESLEHEVSVEQDKFMGAWRMIRRKHIEEKGWKIDTKAMKPFEGEKVFTIPSPGRRANPH
FKWALDTVPLVPPKRRSVPAQAKDSTEPESV
>A0A554WR19|methylxanthine N1-demethylase|EC 1.14.13.178|Tepidimonas aquatica|TrEMBL
MVERDHWWPVALADDVGAAPVPVTLLDEPLVLWRDGAGAVQAFADRCPHRGARLSLGAVV
EGQLRCPYHGWRFDGDGRCRAIPALPGFAPPDGHAACRHAVAQAHGLLWVCLGTPVAPAP
PSLPPLPPRRVVHGPFDVATSAPRAIENFLDTAHFAYVHEGWLGAPTHAEVPPYEVTLTA
DGRPVVPDYPAWQPRATARAQGGAWVRYRYEVLSPYAALLQKQPEGDAPADAYVMWACPT
TPETCRVWFVQHTTDTTTPDAALREFQSAIFAQDRPILESQTPKRLPLFGGEAMCAADRL
SAAYRRYLRAAGITFGVC
>A0A5E7SIF9|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas fluorescens|TrEMBL
MLTNLWYVVLPSSQLTDGLMPVQLLGQPFVAFRDDAGVAHVLSDICVHRGGSLSAGSKVG
NSVQCPYHGWRFGGDGVCTQIPAQPDLRIPAKARVDAYPTLERYGWIWAFLGDLPESERP
PLPALDWIDDPAIRVVSGHFDWQASWDRIIENGLDFAHAPFVHGSTFGDPDHPEIESFEV
ESDAWSGSARMLMRRPARKGLLRRKSSTEFVSVVTVPGFHLSGPCTTLELELPNGWRIYI
VSAHVPIDANRTRTWWMMGRTFLRSRLLDRRFIASNIRIFEQDHAVLKNVRPERVPDSFQ
QEVSLKSDALQIAFRKDVQALELRGWRIDEERLARTFTGRKACAIPSPERRQIRAWAIEP
IPLVDITHESQ
>A0A385XT00|methylxanthine N1-demethylase|EC 1.14.13.178|Dickeya dianthicola|TrEMBL
MTLPLTPPAHSSFEADDWIRLARCWHPVALASGVGPAPTPVTLLDEPLVVYRIGDEIVAA
RDICPHRGVPLSMGSHDGEGIVCPYHGLRFGAGGRCNRVPASQDQSIPAKLHLNTFAARE
QYGLVWVCLAPPDGILPELPVMPHWNDAGFQQIVCPSFDIAGFAGRQIEGFLDVAHFAWV
HTDTFADPDNQQVPDYQPVEAPYGFSVDYVSSVSNFARGSGRQAPEGFVWLRHFEMFLPF
TATLTIHFPDDGRLVIMNAASPVSARQTRLFVPIARNFDLHVPVEDVHAFNLRVFEEDRA
MVESQRPEHLPLDLTLEAHIPADRSSIAYRRGLKKQGYGEFFLA
>A0A2S8BRT0|methylxanthine N1-demethylase|EC 1.14.13.178|Mycobacterium talmoniae|TrEMBL
MMVSVEISVAADRFRAALANRWHAVLTAAELLDRPVGVRLLGRPLVLARLRGRPACLDDV
CRHLGAALSLGEVVDGHALRCSYHGWAYDGGGRCVDIPARRGAPIPRGAQVASYPTEERY
GLIWVCLETPEAAAIPELPEFSDPAFRVTAPRTYEPWRASAPRVVMGALDDTHFGWVHPG
LLGDPDTPEAPDHEAHREGDYLITSYSVEQPGTLSSMGTGICETVNYRNAATPTSIRLVK
RSATGTYVIFMAVQPVDADRSHVYLLTARDFDLDPAGDERYLTFEDTLQAQDRVVIESQR
PWLLPPLESRLALYIRPADLPLIEFQRWLEELGIPQV
>A0A1V5VUY4|methylxanthine N1-demethylase|EC 1.14.13.178|Chloroflexi bacterium ADurb.Bin222|TrEMBL
MSCLRDLCAHRGVALSKGKVIEGALQCPFHGFAYDASGAAVVIPANGGQTPVPSRFKVHA
YPTYEAHGFIWIWWGAEPPADLQPPSFFDDITPDFSYGSAHDSWKAHYSRVIENQLDVVH
LPFVHYNTIGRGNRTLVNGPVVEWLDKNRFRVYVFNEVDHGQTPRKAEEITPPYPPFHLE
FLFPNLWQNHINADVRVVAAFVPVDNEHTLLYLRFYQRFMRIPGLRELVNVLAMPFNVLV
AHQDRRVVITQRPKPSALRSEENLIQGDRPIVEYRRRREALRQAAAASGLSGA
>A0A6N3AUH5|methylxanthine N1-demethylase|EC 1.14.13.178|Phytobacter massiliensis|TrEMBL
MKTPFPTPPAHCTFEPDDWLRLAKCWHPVARACDIGPAPVKATLLDEQLVIYRVKGQVVV
AKDVCPHRGVPLTLGFHDEEGIVCPYHGLRFGEDGRCNRIPSSPDQPVPAKLNLTSFAVE
ERYGLIWTCLAFDPQDPQPLPTMPHWHDDGFQQINCPAFEVNGFAGRQVEGFLDVAHFAW
IHTDTFADPDNQVVPDYNPQETGFGFIADYWSSVGNYPASSEFRAPEGFQWLRHFEMHLP
FTATLTIHFPGEARLVIMNAASPVSSRVTRMFAPIARNFDLHVPVEEVHAFNLRVFEEDR
LMVETQRPERLPLDLTLEAHIPADRSSIAYRRGLKKMGFGDFFLV
>A0A5A5RJT7|methylxanthine N1-demethylase|EC 1.14.13.178|Microcystis aeruginosa NIES-2520|TrEMBL
MTSTDQSQPLPRDDYFHYQNCWYPVLFVQDWQKNPYSFSLYGQPLLIFRDQQGKWGCLLD
RCPHRLAKLSTGQMIAGRLECLYHGWQFETDGKCSHIPQLPVNTPIPRNAKVKSYGVVER
QGVLWVWLGEEETAKESDIPIIKDLEDPNCVHTDYVIDFPYEQGYLLENLLDPAHVNISH
DRSEFGAKRENAQPLAFQILEISARGIRSQWRNSRNPQESWKYLDFLAPNLVHYRFSLPN
PDWCAGLALYGISLSQGRSRLLMRRYQNFAVNSRQYRWRWLEHLRQSRILEDDLPLIQSQ
QQMVEKSRDSLQKLYLPLKSSDALVIELRQWFDRYGDSFPYYQGYTSQRTTAIDLSDPLP
LDRYSRHTVHCRTCSTAHEKMVKTKQIGILMGILLALLAILSPNHSIYQITALIFAILAL
AIAIAANYTRRKFERTYEKKAHTKLQ
>A0A385EQF6|methylxanthine N1-demethylase|EC 1.14.13.178|Acinetobacter baumannii WM99c|TrEMBL
MNAIPTLTPLAMPCNSSFEAKDWEILSSHWYPVARIQDVFNAPQRVTLLDVNMALYKTKS
GEIHLVRDICPHRGVPLTKGWVDGEEIVCPYHGLRYNTEGKCTQIPAQPELTKISDRFSL
IKFPVVQRYGLIWTSIHGRDIDKANIPVLDTWDDAEHQAILPPFVDIGGSSGRQLEGFID
VAHFAWVHHNAFANRDNPVVPKYHTERTNYGLKTVYISNVSNYPHELKHLEPEGFLWKRT
FEVYPPFSAVLTVDFPESGILKILNACCPISSNKTRLFVPLTRNFDQTGDLEKVYAFNAQ
IFAEDQDMVESQKPEELPLDLMMEAHFEADRSSTTYRRILAEWGLSKRYTV
>A0A0H2M5V5|methylxanthine N1-demethylase|EC 1.14.13.178|Variovorax paradoxus|TrEMBL
MLVTQQPVFRKFWHAVMPLTELANGPKPFTLLGEDIVLFIDADGQPAALRDRCCHRTAKL
SKGWCVDGEGKACGQGAIQCGYHGWTYDRSGQVIRIPQYEADRKISPEYRTTAYRCTARY
GYAWVALEEPIADIPAIPEFDDPGYRTIFQFYEEWQTSPMRALENSFDNSHFSFVHRATF
GVAASPKPSKYELVENEGGFHAETVIEAVNPVKFHAISGVTEPITTRHMRNAYFLPFSRR
LDIEYPSGVRHIIINCFTPIDDGRMQLCQWLFRNDTEADCTAQMLIDFDEAVTREDKDIL
ESTDPDALVDTRRRGVEYSMESDRPGMLIRKHLMQLLAKHGEAEVHRGMTGAVIPIAKAA
>A0A0M0ELP0|methylxanthine N1-demethylase|EC 1.14.13.178|Komagataeibacter europaeus|TrEMBL
MTTAASTRPATTHSLPRTMTFDVDDWNILARCWYPVALVRELGEQPLGVTLLDAPLVVYR
AGADIVIADDLCPHRGVPLSMGKGDGQTVACAYHGFRFGGQGKCVRVPAHPDSGIPSKLN
LRTYPAVERYGLIWTCLRPEGDAVAIPPMPHWNDPAFQQINCPWIDIAGFAGRQVEGFID
VAHFAFVHTDTFADPENPVVPPYKTRITPDGFEAEYRSSVGNYPIGKSDRGRPGFEWLRH
FRVHVPFTATLEIHFPDNGRLVIMNAASPVSARQTRMFAPMCRNFDRDLPLQDVYDFNLK
VFEEDRALVEAQKPENLPLDPTLEAHVMADRSSIAYRRALRTMGLSQFFTA
>A0A0M0EIA4|methylxanthine N1-demethylase|EC 1.14.13.178|Komagataeibacter europaeus|TrEMBL
MKRWQPVSVLSDIRRGEVAGVRIGGREVVLWREDAPTPTLHAWEDRCPHRGMRLSFGFVR
DDALGCLYHGWQFGGTARCRLIPAHPQVRVPASIHVHAYGVREHAGLAWVSMDGAEDFPA
GGTGPDNVLPVRTLHVKASVGPLRHAAGIAPDAGIAWHGPVGLAVHEPVAGQAMLHVVRV
ADADGPSSPALSRWAEQLRDAVESGAGIAPVMNGLIAGEMA
>A0A679K8G1|methylxanthine N1-demethylase|EC 1.14.13.178|Methylobacterium bullatum|TrEMBL
MLSSPPPQAKADTAKNPATDEAALDPDAMRQPLPDAFYCVGRADTLKPGSLRAVELNGEQ
IVLGRDKAGAAFAMRDRCPHRGMALSKGRFDGDAVTCPFHGWRFGTDGRCRDVPTLSSAD
AADFTRITVQRFPIRESAGFVWVNPYLGPPGGDLPPLPELGFEAAGSLVVELVVEASFDL
TTLSLVDPGHVAFVHDSWWFRPSKELREKVKTFTPTPHGFTMSSHATTTSSPVYKLLGGV
PEVEIEFRLPGVRLERIEAGPKRVANYTFATPLTHNRTMLTNALYWNMPVLNLLKPLARP
LMRQFLTQDQQVLQHAQAGLDRKPTMVLFGQSDLPSQWYFRLKREALQAAREARSFRNPL
VQQELRWRS
>A0A2J7YH07|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas putida|TrEMBL
MLVTKQPVLRRFWYALLPMTALEDGPKPFTLLGEALVLWKRPDGTPVAMQDRCCHRTAKL
SKGFVSAEGNIACGYHGWEYDCTGTCVKIPQNPTGAIPPGAAVKAYHCQEKYGYAWVSLD
DPLQPIPEFPEDGTPGYRRIFQFYEEWKTSPLRVMENSFDNSHFSFVHKANFGLFDQPQP
ASYEFRETDYGFEAETRVPIRNPEASFRITGTTEPITQRHLLNRYYLPFSRRFGCMYPDS
GIHHIIYNCATPIDDNRLMLVQWLYRNDSEEQCSTQELIDWDAAITAEDRDILEATDPDA
CVDTRRRVELHMPSDKPGLVIRRQLLGLLEAHGESEVFLSH
>A0A0D8HGG0|methylxanthine N1-demethylase|EC 1.14.13.178|Acidithrix ferrooxidans|TrEMBL
MNSQANGTIRENAVTSQSLDVLKNDDPRLGYFYHPVALETEITDGWLKATLLDVDWLIVK
TFDGSLVAYRDRCPHRSAPLSTGTVCDGIISCGYHGHRFDDSGRCIEIPAIQDQAHIPPT
ARLEVAYGVICRYGIIFLAPKEPNAPIIEISEATDSAFMAGYLVPKNVRQHCGYLADNFL
DMAHFPFVHTQTFGDEATRLVDNYEIISKLGGFTARYAHQFANREDPGVALGERELIQRR
ELIYTYVAPFSLSLRISFLEADGVNMIGFFISPVRDGVSRLFCILWRNDMNGTQAEMDEA
VAFEERVLQEDLLLHEQYKTDGFPLDLRFEVHTKADRITVALRNELRRRLSEDAM
>A0A679JGG9|methylxanthine N1-demethylase|EC 1.14.13.178|Variovorax paradoxus|TrEMBL
MLVTQQPVFRKFWHAVMPLTELASGPRPFRLLGEDIVLFIDASGQPAALRDRCCHRTAKL
SKGWCVDSEGQACGTGAIQCGYHGWTYDRSGQVIRIPQYEPGRTISPDYKTTAYRCTARY
GYAWVALEEPIADIPAIPEFDDPGYRTIFQFYEEWQTSPMRALENSFDNSHFSFVHRATF
GVAASPKPSRYELVENESGFYAETVIEATNPVKFHAISGVTDPITTRHMRNAYFLPFSRR
LDIEYPSGVRHIIINCFTPIDDGRMQLCQWLFRNDTEADCSAQMLIDFDEAVTREDKDIL
ESTDPDALVDTRRRGVEYSMESDRPGMLIRKHLMQLLARHGEAEVHRGMSAVIPVAKAA
>A0A5E6Z4M9|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas fluorescens|TrEMBL
MLTNLWYVVLPSSQLTDGLMPVQLLGQPFVAFRDDAGLAHLLSDICVHRGGSLSAGSKVG
NSVQCPYHGWRFGGDGVCTQIPAQPDLRIPAKARVDAYPTLDRYGWIWAFLGDLPESERP
PLPALDWIDDPAIRVVSGHFDWQASWDRIIENGLDFAHAPFVHGSTFGDPDHPEIESFEV
DSDAWSGSAQMLMRRPARKGLLRRKSSTEFVSVTTVPGFHLSGPCTTLELELPNGWRIYI
VSAHVPIDANRTRTWWMMGRTFLRSRLLDRRFIASNIRIFEQDHAVLKNVRPERVPDSFQ
QEVSLKSDALQIAFRKDVQALELRGWRIDEERLARTFTGRKACAIPSPERRQIRAWAIEP
IPLVDITHESE
>A0A811GA74|methylxanthine N1-demethylase|EC 1.14.13.178|Acinetobacter bouvetii|TrEMBL
MNAIPVLNLFTQPQCSQFDPNDWNILAQHWYPVVQIQDVTTQPQQVQLLDVKMAIYKTES
GEIHLVRDICPHRGVPLSKGWVEGENIVCPYHGLNYNAQGKCVKIPAQPELTQISDRFTL
TKFPVVEKYGLVWTSLFSRDESEANFPVLETWDSDEHQSILPPFVDIAGSSGRQLEGFID
VAHFAWVHNKAFADRDNPVVPKYETERTDYGLKTIYISTVSNFPRSLRHLEPENFLWKRE
FDVYPPFSATLTVYFPNNGILKILNACCPVSHNQTRLFVPLTRNFDTTGDLQAVYDFNAQ
IFAEDQDIVENQKPEELPLDVSMEAHFAADKSSTTYRRILAEWGLSKRYVV
>A0A8H2NRF9|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas fluorescens|TrEMBL
MLYKGEWNREEVDYQALVNQWHVVALSEDLDASKPKAVRLLGEDLVLWRDELGGVHAWKD
YCGHRGAKLSLGCVKQGQIECPYHGWRYDRHGNCKLVPAHPDRAGPSSERLIFRHFAQEQ
FGFIWASLEQPDRPLPDFAQWEDSSYRIVFAGPYHYKANALRALENFIDASHFPFVHANL
NGLPDAPEPLKKYTVSLDDRGLHSSEISVFQPYGDHRAIPVTARYKYSVLNPTTAYFKKK
TGETERFCTFFNATPVDEAECIIWLIVAINFGPDLTLEQILSRQNIVFEQDRHIVEAQRP
ARLPLDPKAEMHVNSDRMGLEYRRWLKTLGEASRNRSFTQPIRTVSL
>A0A1V5LV86|methylxanthine N1-demethylase|EC 1.14.13.178|bacterium ADurb.Bin425|TrEMBL
MKVPSGWYAVLSAAELKPNKPLGQKRFGEDLVFWRDQSDRPAVLKDLCPHRSVKLSGGEV
CQNGNHIACPFHGFQFDSQGQCRHVPETGKEAPNLRVKTWQSAEKNGFIWLYVPKNEDDI
GSEDSIPWFNELQEKKFCYSEFKESWNIHYSRCIENQLDYAHLPYLHRTSIGKNFDVQGK
YDFLLDESSIKVVLKSGYFHFKFPNIWYLNISPTLKQMLAFVPVDDNTTVMYVRAYQAFV
TLPLVEKLVGKVLAASNRVILNQDKAAVITHSPSSSLLASDEKLYPSDRGIAWFRKQFSE
KAVEV
>A0A564G4Y3|methylxanthine N1-demethylase|EC 1.14.13.178|Methylobacterium dankookense|TrEMBL
MSVSPLPSQRPDDALDPAAMRQPLPDAWYCVAESRALKGNGLTAVALNGEQLVLGRGADG
TAFALRDRCPHRGMALSKGPFDGDTLMCPFHGWRFGTDGRCRAVPTLSTHDAADFSRIAV
QRFPVRESAGFVWVNPSLNEDGPVPAIPALDFEPAGSLVVALEVEASFDLTTLSLVDPGH
VAFVHDSWWFRPSKELREKVKTFQPVEHGFVMTSHATTKSSPVYRLLGGVPEVEIEFRLP
GVRLERIMAGAKRVANYTFATPLTANRTLLTNALYWSMPALNLLKPVARPLMRQFLTQDQ
QVLQHAQAGLDRKPTMVLLGDGDLPSQWYFRLKREALESARAGRPFVNPLERRELRWRS
>A0A150HQ98|methylxanthine N1-demethylase|EC 1.14.13.178|Acinetobacter venetianus|TrEMBL
MNTKNIATFNPDLPVHMTFSEHDWHLLAQHWYPIALARDISEQPTAAMLLDMPLVIYKMA
DQLVVAKDACPHRGVPLSLGHNDGNGIVCRYHGLRFGENGKCNRIPAHPQHKISERFH
>A0A383RXH3|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas reidholzensis|TrEMBL
MLVTKQPVLRRFWYALLPMTALDDGPKPFTLLGEALVLWKRPDGTPVAMRDRCCHRTAKL
SKGFVSEDGNIACGYHGWEYDCSGTCVKIPQNPSGAIPPGAAVKAYHCQARYGYAWVALD
DPLQPIPDFPEDGAAGYRRIFQFYEEWQTSPLRVMENSFDNSHFSFVHKANFGLFDQPQP
ASYEFRETDYGFEAETRVPIRNPEASFRITGSTAPITERHLVNRYYLPFSRRFGCMYPDS
GIHHIIYNCATPIDDGRLMLVQWLYRNDSEEHCSTQALIDWDAAITAEDREILEATDPDA
CVDTRRRVELHMPSDKPGLVIRRQLLGLLEAHGESEVFHSH
>A0A347WB90|methylxanthine N1-demethylase|EC 1.14.13.178|Komagataeibacter saccharivorans|TrEMBL
MERWHSVSVLSDIRPGEVAGVRIDGHEVVLWREDTPAASLHAWEDRCPHRGMRLSFGFVR
GDAMGCLYHGWQFGAAGRCRLIPAHPQVRVPASIHVRAYGVREHAGLAWVNMEGTDGFPV
HATHWPDDVQPVRSVHVRRGATQLRQAIGLEAVDGMAWRGSVGLAVHEPVAGQAMLHVVC
ARSGEPAPTPVALSHWASRLRDAVESGNPTATIMGELA
>A0A509EDU3|methylxanthine N1-demethylase|EC 1.14.13.178|Methylobacterium symbioticum|TrEMBL
MSVSPLPSQRSDDALDPTAMRQPLPDAWYCVAESRALKRNGLTAVALNGEQLVLGRGADG
APFALRDRCPHRGMALSKGPFDGDTLMCPFHGWRFGTDGRCRAVPTLSTHDAADFSRIAV
QRFPVRESAGFVWVNPSLQEGGPVPAIPALDFEPAGSLVVALEVEASFDLTTLSLVDPGH
VAFVHDSWWFRPSKELREKVKTFQPVEHGFVMTSHATTKSSPVYRLLGGVPEVEIEFRLP
GVRLERIVAGAKRVANYTFATPLTANRTLLTNALYWSMPALNLLKPVARPLMRQFLTQDQ
QVLQHAQAGLDRKPTMVLLGDGDLPSQWYFRLKREALESARAGRPFANPLERRELRWRS
>A0A1X7BNI8|methylxanthine N1-demethylase|EC 1.14.13.178|Roseovarius aestuarii|TrEMBL
MFQATDHSKAPSVLPRNCTFTESDWKILAGFWHPVAVAHDIDAKPVAARLLDVELVIYRT
SQGISVARDICPHRGTRLSAGWIEGDNLVCPMHGLCYDHAGQCTKNPSVGDPNARIPPRM
RLQSLLTEERYGIVWACLADTPSHPLPVWPGIGDDTLENLHIPGDTWHAAASRHVENFND
VAHFPFVHKETFGGYEEDPIPAYEVEATDYGLTFDIPYLEVGNRFPDDVEGDERNVVYTY
QLTLPFSTIIIIKPTEGPYAQYFADTVCPVSAHETRIFQVVTDTNGKPDADFLIKESLMI
NNEDKSMVEGQRPEDLPLDMKEEIHIPADRMSVEYRRALAKLGLGAPFSS
>A0A5E6SHB2|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas fluorescens|TrEMBL
MIKDRTLPLNCTFIESDWRILAAHWYPIAQSLAVQAEPIKAMLLDEPLVIYRIDDDLVVA
RDVCPHRGVPLSMGKSDGQGVVCAYHGLRFGHGGRCNKVPASPSAAIPSRMQLFTYPAVE
RYGLVWTCLDPQEDTVDIPKMPHWDEPEFQQIVCPSIDIQAFAGRQVEGFLDVAHFGFVH
TETFGDPNNTEITPYRPVETPKGFETHYRSTVGNYPIGVDGRAPDGFNWLRHFEVHLPFT
ATLTVHFPDDGRLVIMNAASPVSAKVTRMFAPIARNFDKDLPVEDTHAFNLRVFEEDRLI
VESQKPERLPLDPALEVHIPADMSSIAYRRGLRSQGLSQFFLS
>A0A645D0W2|methylxanthine N1-demethylase|EC 1.14.13.178|bioreactor metagenome|TrEMBL
MIENTLWHPVAQSHEVVKDAPLSVTLLDQAVVLWRGDDDVAQAFVDRCPHRGARLSMGRV
ENGHLECPYHGWQFAPGGQCVKVPAVPGFVPPATQRVKAFEVQEAYGLVWVRMENAEAPD
ALPAFAAEADAHLRKVNCGPYDVAASAPRIIENFLDMSHFGFVHEGWLGSRDATAIAAYK
VENTANGVLATGCKAVQPQSNLHSTTAAEVEYTYEVTAPYTAVLTKIPEEGTSKAGWRES
IGLFICPITPETSRVWFRLAVADFESSDEKLREFQHTIFVQDQPVLESQRPKALPLDPRA
EMHSAADRMSSAYRRFLKAAGITFGVC
>A0A290LJR1|methylxanthine N1-demethylase|EC 1.14.13.178|Paraburkholderia caffeinilytica|TrEMBL
MEHLPLIKDNQYLRHFWHPVCTVAELERAKPSSFGPLAVTLLREQLVVARLDGKYVAMRD
RCAHRSAKLSCGQVVGSELQCPYHGWKYDAAGACTKIPACPDSPIPNKARVERFDCEEKY
GLLWVRLDSSFNCTEIPYFSAADDPKMRIVVQEPYWWNASAERRWENFTDFSHFAFIHPG
TLFDPNNAEPPIVPMDRVNGQFRFVYETPPGMDVPDQAPIGTFTYHCSMPFAINLAVEKY
STNSLHVLFNVSCPIDETRTKNFLIFAREQGSDSDHLHIAFNDVVFAEDKPVIESQWPAQ
MMADEVPVITDKVSVQYRKWMRELSEAARDGAEAFKAALHEPVIESERQYSDLRTV
>A0A6J5BYT2|methylxanthine N1-demethylase|EC 1.14.13.178|Paraburkholderia sediminicola|TrEMBL
MSATNPHQVLETRMSSAAATATAATTRPLTFQRSPALPRNCTFDSHDWEILSRYWHPVAF
AAEVTDKPISVTLLDEPLVVFRSNGQLVSARDICPHRGAPLSQGWVDNGNIVCPYHGLAY
GNDGKCKHIPSQTDGPIPERLHLVTYATQEAYGLVWVSLGGGTEALPAFPNWDDPDFQQI
LPPSIDINASAGRQTEGFIDVAHFAWIHHDSFADRHNPVVPQYSVERRERGMHAEYVSTV
SNFPKSMQHRAPEGYLWHRFFDVDVPFFARLTVHFPENGRLSILNAASPVSARKTRLFVP
IVRNFDKDLPLEDVYAFNRQVFEEDRAIVEQQRPEDLPIDRAAEAPILADRSSGAYRRAL
AEIGLGQAYVR
>A0A679J275|methylxanthine N1-demethylase|EC 1.14.13.178|Variovorax paradoxus|TrEMBL
MNDIQDTARWHPVARAADLRPGANIVAGFAEGQELALWRAADGTPQAWENRCPHRSVRFT
LGQVVGNRLSCAYHGWQYAAGSGQCTSIPAHPAMQAPRNVCAKTFAVAEAAGMLWVHLSP
EAPPAPSALADAIPAGWHFCRTLTARASAGAVRAAMQRRGLSFDDATGAWTGRLGGTRAA
ALVLDAQPALAFVHLWSDAAPGSDAMKNLHAAARSLRGDIEALPTPE
>A0A5E7HVQ7|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas fluorescens|TrEMBL
MIYTGNWNRDAIDYQALLGQWHVVCPSLDVGSEQPKAARLLGNDLVLWRDDTGQVHAWQD
YCGHRGARLSLGHIKKGEIECPYHGWRYNPEGQCTRVPAHPEQSGPASQRLVYRHLAQER
YGYIWVSLKTPQRPLPEFPQWDDVRYRKVYAGPYCYEANALRSVENFIDASHFPFVHANL
NGLPDAPEPLKKYTVHKDERGLHSSEISVFQPYGDHRGIPINARYSYSVFNPTTAYFMKK
TGETERFCTFFNATPVDEAQCIIWLIVAINFGTDLSLEQILSRQNMVFEQDRHIVESQRP
ARLPLDAHAEMHVVSDRMGLEYRRWIRALGEAASLDGLKPTIKTVSI
>A0A7U2ZM47|methylxanthine N1-demethylase|EC 1.14.13.178|Klebsiella africana|TrEMBL
MKTTTPTPPAHCTFDPEDWLRLARCWHPVARACDIAGAPVKATLLDEQLVIYRIKGQVVV
ARDVCPHRGVPLTLGFHEEEGIVCPYHGLRFGEDGRCNRIPSSPGQPIPAKLHLTSFAVE
ERYGLIWTCLACDPDNPPPLPTMPHWDDAGFQQINCPAFEVKGFAGRQVEGFLDVAHFAW
IHTDTFADPDNQQVPDYTPQETPFGFVADYWSSVGNYPASSDFRAPDGFQWLRHFEMHLP
FTATLTIHFPADAKLVIMNAASPVSSRVTRMFAPIARNFDLHVPVEDVHAFNLRVFEEDR
LMVETQRPERLPLDLTLEAHIPADRSSIAYRRGLKKMGFGDFFLV
>A0A6J5FNC4|methylxanthine N1-demethylase|EC 1.14.13.178|Paraburkholderia caffeinitolerans|TrEMBL
MEHLPLIKDNQYLRHFWHPVCTVAELERAKPSSFGPLAVTLLREQLVVARLDGKYVAMRD
RCAHRSAKLSCGQVVGSELQCPYHGWKYDAAGACTKIPACPDSPIPNKARVERFDCEEKY
GLLWVRLDSSFNCTEIPYFSAADDPKMRIVVQEPYWWNASAERRWENFTDFSHFAFIHPG
TLFDPNNAEPPIVPMDRVNGQFRFVYETPPGMDVPDQAPIGTFTYHCSMPFAINLAVEKY
STNSLHVLFNVSCPIDETRTKNFLIFAREQGSDSDHLHIAFNDVVFAEDKPVIESQWPAQ
MMADEVPVITDKVSVQYRKWMRELSEAARDGAEAFKAALHEPVIESERQYSDLRTV
>A0A5E6Q8F1|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas fluorescens|TrEMBL
MLTNLWYVVLPSSQLTDGLMPVQLLGQPFVAFRDDAGVAHVLSDICVHRGGSLSAGSKVG
NSVQCPYHGWRFGADGVCTQIPAQPDLRIPAKARVDAYPTLERYGWIWAFLGDLPESERP
PLPTLDWMDDPAIRVVSGHFDWQASWDRIIENGLDFAHAPFVHGSTFGDPDHPEIESFEV
DSDAWSGSAQMLMRRPARKGLLRRKSSTEFVSVATVPGFHLSGPCTTLELELPNGWRIYI
VSAHVPIDANRTRTWWMMGRTFLRSRLLDRRFIASNIRIFEQDHAVLKNVRPERVPDSFQ
QEVSLKSDALQIAFRKDVQALELRGWRIDEERLARTFTGRKACAIPSPERRQIRAWAIEP
IPLVDITHEPE
>A0A2K9J0Q7|methylxanthine N1-demethylase|EC 1.14.13.178|Virgibacillus dokdonensis|TrEMBL
MKKDRLWQEWHPVLKETELHEDPKQVHILGERVVLFRNQKGVHAFKDLCIHRGAALSLGK
VKNGNIVCPYHAWEYNDEGICVKIPALPCERAIPQKAKATVYHCQVYAGLIWVNLSEQPL
PLLNYPEYSREGYRTAICGPYKVSANAPRVIENFLDISHLMFVHGGLLGDEDHAEVQNYD
VTFVDGRFITSEIPIYQPNPDGRSVGGYTDYVYEILNPTTARFTKSVEGSSEEFIVLITV
VQEADEQTKVFMLLTRNYDLDKPDEPFVEFQDLIFKQDLDVVESQKPELLPLDLQAEMHL
KCDALTIAYRRWLDELGIETGTTPNYRKKREIVPS
>A0A150I1X5|methylxanthine N1-demethylase|EC 1.14.13.178|Acinetobacter venetianus|TrEMBL
MNTKTIATFNPDLPVHMTFSEHDWHLLAQHWYPIALARDISEQPTAAMLLDMPLVIYKMA
DQLVVAKDACPHRGVPLSLGHNDGNGIVCRYHGLRFGENGKCNRIPAHPQHNISERFHLK
TYAALEKYGLIWCNLTAASDALANIPEMPYWEHADFQQLVCPSVDLNCFAGRQLEGFIDV
AHFAWVHPDTFGDPENVEVPDYTTTETTYGFEADYISSVGRYPIGTDQRGKDGFQWLRHF
EISLPFTATLTIHFPNETKQVIMNAASPVSARQTRLFPPICRNYDKDLPIEDAYKFNLEI
FEEDRLIVETQKPEYLPLDLSMEAHFPADRSSSMYRKLLRKMGFSPIFAA
>A0A518GEW0|methylxanthine N1-demethylase|EC 1.14.13.178|Aureliella helgolandensis|TrEMBL
MAWHQLCNLSTLKNGQGQEFLVGKTIVALFLQDSKLYATDGMCAHQGGPLAQGLVDGECI
TCPWHGWQYDLNTGNNLRTGKKMLDRYDVEVRGDQVWIEIPCESSEGASTAI
>A0A6N3HYS8|methylxanthine N1-demethylase|EC 1.14.13.178|Enterobacter agglomerans|TrEMBL
MKREPTPPAHCTFEPEDWLRLAKCWHPVARACDIGPAPVKATLLDEQLVIYRINGQVVVA
RDVCPHRGVPLTLGFHDEHGIICPYHGLRFGEDGRCNRIPSSPDQPVPAKLNLINFAVEE
RFGLIWTCLAFDPDNPVPLPAMPHWDDDGFQQINCPAFEVNGFAGRQVEGFLDVAHFAWI
HTDTFADPNNQLVPTYQPQETPFGFVADYWSSVSNYPASSDVQAPEGFQWLRHFEMHLPF
TATLTIHFPGESRLVIMNAASPVSSRVTRMFAPIARNFDLHIPVEDVHAFNLRIFEEDRL
MVETQRPESLPLDLTLEAHIPADKSSIAYRRGLKKMGFGEFFLV
>A0A1J5RUJ8|methylxanthine N1-demethylase|EC 1.14.13.178|mine drainage metagenome|TrEMBL
MLVTRQTVLRRFWYALMPLHALDAGPQPFTLLGEKIVVWKGADGHPAALRDRCCHRTAAL
SRGFVDEAGHIVCGYHGWTYDCAGACVRIPQNEDGAIPAGARVESFRCEARYGYVWVALG
EPLAPIPDFPEDGDARYRRILQFHERWNTSSLRFLENAFDNAHFSYVHKANFGIFEQPKP
QSYRLEVTDYGFEAETRVPIKNPSASHRVTGTTAPYTERHLLNRWMLPFTRRFGCQYPES
GVHHIIYNCATPIDDGSITLAQWLYRNDSETDCSTEELIAWDRPIVDEDRDILEATDPDA
CVDTRRRMEFHMASDRPGLLIRKRLQDLLHAHGEEEVFREAPTYSSTGTETLPLKRLGT
>A0A0Q9YMK7|methylxanthine N1-demethylase|EC 1.14.13.178|Candidatus Berkiella aquae|TrEMBL
MNSLLQHYWYIVAESSELTADKVLARQILDEWLVVFRGEDNKPCVMRDKCLHRCARLSKG
EVSKGLLTCPYHGWVYNGKGQLVSVPAHFGQRKEEVMNVSHAFACIEQEGYIYVCLSNKP
LASKPYAMPQFNNGRYKKVRLVNVFNNTLANCVENFIDIPHTAFVHQGIFRKKANEQIKA
KVKRENGHIQIDYENEKNNLGSFSWLLNPKKKVIFHQDNYYAPNITHVIYRLTGKWEYRI
TSQTVPITNETSIVYTEICYDFGLWNYHPFTKWLIKRQAQKVIDQDMNILNDQMTVIKKY
GQKFSTTSADLIHHYTSEIIDALNNGLEPQMLPDQEKEITFWV
>B1FSR2|methylxanthine N1-demethylase|EC 1.14.13.178|Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M)|TrEMBL
MLVTRQKVLRRFWYAVVPMSHLDDGPKPFTLLGENIVLWKGAGGKPHALRDRCCHRTAKL
SKGFVDSDGNIACGYHGWTYDCTGQCVKIPQNGAGEIPSRAVVQSYRCEERYGYAWVALD
EPLQPIPEFPEETAPGYRRILQFYEQWNTSPLRMMENSFDNAHFSFVHKSNFGLFDQPRP
SKYEFRPGEWGFEAETRVPIRNPQASFRITGTTDDITERHLVNRWFMPFARRFGCMYPAS
GIHHIIYNCATPIDDKTMMLVQWLYRNDTEEQCSTQALIDWDRPITDEDREILEATDYDA
CIDVSRQQECHMVSDQPGLLMRRMLLKLLEDHGEKEVFRIDAEA
>A0A2S0Q5F7|methylxanthine N1-demethylase|EC 1.14.13.178|Nodularia spumigena UHCC 0039|TrEMBL
MSSEFNFFQQWYPLSPVEDIDPTRPTPVTLLGIRLVIWKPKSSETYQVFLDQCPHRLAPL
SEGRVDEKSGNLMCSYHGWQFDSQGICTHIPQAEKPEIVTKNEKIFCVISLPVRQANDLL
WVWPDANSAEAAANTPLPLSPQVDADKGYVWSSYVRDLEYDWETLVENVADPSHVPFTHH
GVQGKREYATPIPMEVVQSTSKLIEAMTSGRFKTTITFEPPCRLEYAINLGDSGEKKVGL
VTYCIPVSPGKSRIVAQFPRNFAKTLHRLTPRWWSHINTRNLVLDGDMIVLHQQENFLQQ
RQAVESWKTIYKLPTSADRLVIEFRNWFDKYCFGQLPWSEVGITVPPSPQINDNRSVLLD
RYSQHTQHCSSCRNALKVIQRLQVGLLIYSTSIIAGVALLPDALRIKLGLPLVITAALSM
AAYSWLKFRLIPKFYFVDYIHPEKV
>A0A554X1Y6|methylxanthine N1-demethylase|EC 1.14.13.178|Tepidimonas thermarum|TrEMBL
MVERGHWWPVALPGDVGTAPLPLTLLEEPLVLWRDATGAVQAFADRCPHRGARLSLGRVA
DGQLQCPYHGWRFDGQGQCRQIPALPGFAPPASHAAQRYAVMEAHGLLWVCLGQPQAAPP
ALPVLPARRLVHGPFDVATSAPRVVENFLDTAHFAFVHAGWLGEPQQAQVPHHALTHTDD
GRPVVPDYPAWQPRATAGAQQGAWVRYHYEVLSPYAALLHKQPEGDAPSDAYILWACPRT
PESCRVWFVQHTTDTATADDELRRFQATIFAQDQPVLESQTPKRLPLQGGEVMCAADRLS
AAYRRYLRTAGITFGVC
>A0A6N7C9M1|methylxanthine N1-demethylase|EC 1.14.13.178|Rhodococcus sp. T7|TrEMBL
MTTSIPTPTKRELAEASMRRSWFPVARLCDLDKPQTATLLGVNLVIYRDGEGRISVQSRR
CPHRGGDLSMGDVHRNSIGCPYHGWEFSSTDGSCSRIPSLADQGKIPPRASIATYPAVER
FGHVWTVLEDPIRDMYEIEEWQGLDLEWLAADPIDSSVGVGVTIENFRDVAHFPFVHKVS
MGPTPEVVEPLNVNRDGLDVWMDRPLDAGSGDWANDGNCMMRYRCSAPGLASITYHYEKL
GRRIVAGFPSPIDYEHVKIFWGVANEVGYRGADLEECLRVEEMVYLEDIPIVEFIEPREI
PWDSEFQEFSVPADLFTLNYRRSFTELMNRVKDGSHVNEFV
>A0A4P6WUQ8|methylxanthine N1-demethylase|EC 1.14.13.178|Hydrogenophaga pseudoflava|TrEMBL
MIERQLWHPVIAGIHLRDAPQSVSLLGQDVVLWREHGHEGPHGVVHAWADRCPHRGAKLS
LGRVLTHLHGARLECPYHGWQFAGDGAASQGHHGAPVSVGRCVHVPAAPAFEPPAAHCAQ
VFEAQERHGLVWVRLERPDLSQLPASLAQPPAFEPWDDPLWRQVVCGPYAVETSAPRLVE
NFLDLSHFGFVHEGWLGARSHAQVDTGRVDEDADGVHARECKAWQPRGYAGAEEGGWVAY
RYEVPHPFAAILRKDAAEGDPVSNAIALFIRPDGPEACTAWFAMATLGDLSDDEELRAFQ
DAVFAQDKPIVESQQPRRLPIGKDGAIPEVHGPADRMSSAYRRYLARTGVSLGVC
>A0A2S3W2I2|methylxanthine N1-demethylase|EC 1.14.13.178|Novacetimonas maltaceti|TrEMBL
MTTTTHPRPTNAHVLPRNMTFDVDDWNILARCWYPVALVRDLGDGPMGVTLLDAPLVIYR
AGDSIVIADDLCPHRGVPLSMGKGDGTTIACAYHGFRFGGQGKCVRVPAHPDSAIPSKLN
LRTYPAVERYGLIWTCLRPGDEAPAIPPMPHWDDPAFQQINCPWIDIAGFAGRQVEGFID
VAHFAFVHTDTFADPENPVVPPYRTRVTPDGFEAEYRSSVGNYPIGKSDRGRPGFEWLRH
FRVHVPFTATLEIHFPENGRLVIMNAASPVSARKTRMFAPMCRNFDKDLPLQDVYDFNLR
VFEEDRALVEAQKPENLPLDVTLEAHVMADRSSIAYRRALRTMGLSQFFTA
>A0A1Y5T647|methylxanthine N1-demethylase|EC 1.14.13.178|Pacificibacter marinus|TrEMBL
MTMTGWIPLSLSHDIEAGSSAGAVLNGAEVVVWRDTDGRPHIWEDRCPHRGMKLSFGFVR
GDHIACLYHGWEFGETGQCQKIPAHPDLEVPKSICAQTYSVAEAAGMIWVHTPLETTEAN
TSPSPSAPTSRVAHCVRSLYLDVPLERALAALPAAFGASVKVENSVASINAPLVDLHIGL
HPVTDTQCALHITAEGQPDTAVLLDILARAEKLRGSLEAELETAR
>A0A5E7LYD9|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas fluorescens|TrEMBL
MLTNLWYVVLPSSQLTDGLMPVRLLGQPFVAFRDDAGVAHLLSDICVHRGGSLSAGSKVA
NSVQCPYHGWRFGGDGVCTQIPAQPDLRIPAKARVDAYPTLERYGWIWAFLGDLPESERP
PLPTLDWIDDPAIRVVSGHFDWQASWDRIIENGLDFAHAPFVHGSTFGDPDHPEIESFEV
DSDAWSGTAQMLMRRPARKGLLRRKSSTEFVSVVTVPGFHLSGPCTTLELELPNGWRIYI
VSAHVPIDANRTRTWWMMGRTFLRSRLLDRRFIASNIRIFEQDHVVLKNVRPERVPDSFQ
QEVSLKSDALQIAFRKDVQALEQRGWRIDEERLARTFTGRKACAVPSPERGQIRAWAIEP
IPLLDISQEEE
>A0A5S9N0E4|methylxanthine N1-demethylase|EC 1.14.13.178|Zhongshania aliphaticivorans|TrEMBL
MLINLWYVAEWSETVKDKPVKVKLLGQNFVLFRDQAGKVSCLSDVCLHRGGSLSGGRTIR
DCVACPYHGWQFNGDGKVEFIPSEGRDFKIPDRARVDAYPTEERYGMIWVFLGDAPEEER
IPIPEFPEYDDTANWRALHDNWDWKAEAARVVENGIDIAHASFVHPMFGYEETAQENHIK
NVEYHDHWARSWNEQYPPELKGGFLNWRKLIRSDRQPTETIPSWYLAGMVVRIQINLNAK
MSLIMFDANTPIDDHTTRTFAVQLRSFVKHPLFDAGSKKRLHKIFREDQAILEQASPNYL
PETLANELSVKDDRFMSSFRRARRNLVEEKGWQIDSAKVREFDGRKAFAIPSPNRRERTD
LRWVMDAVPLIPPLESVVKLVDQTELS
>A0A7K0DJY3|methylxanthine N1-demethylase|EC 1.14.13.178|Nocardia aurantia|TrEMBL
MLKNFWYAVEFASKVGTEPRRVVCLGQNFVLFRTESGAVSCLSDLCVHRGGALSMGTVSG
DLITCPYHGWQYNSGGVCVRIPANAPERNIPRKARVDAYPTVERYGMVWAFLGDLPEEQR
PPIPEIPQWGDPAFRAVEVEMELDANYERTFENVVDASHTPFVHGTAFGNPDSPQIPDYE
VQQTDWSAEADIKMSPPPPKGLWGLLARRKERPEYVTVTNGWYLPNVVKLHVRLPIGDLI
LYDFNIPLSQDRTLVKILGFRSFFTGAWADGNARKRIEKILLQDRPVVESQRPELLPFDL
ADELHVRSDALQIAYRRRRAQLIEDGWWVGDSDVVTGDSPHRSATVIASPVRRENPELAS
AWVHKTRNGGSPQ
>A0A811GH36|methylxanthine N1-demethylase|EC 1.14.13.178|Acinetobacter bouvetii|TrEMBL
MNAIPVLNLFTQPNGSAFDPSDWNILAQHWYPVARIQDVSTTPQQVILLDVKMALYKTES
GRIHLVRDICPHRGVPLTKGWVQGEEIVCPYHGLHYNAEGKCSKIPAQPELTKISGRFSL
TKFPVVEKYGLIWTSLFSRDESEANFPVLETWEAEGHQAILPPFVDIGGSSGRQLEGFID
VAHFAWVHHQAFADRENQMVPKYHTERTDYGLKSIYISNVSNYPHSVQYLEPEGFMWTRE
FDVYPPFSATLKVYFPNDGILKILNACCPVSHNKTRLFVPLTRNFDTTGDLQAVYDFNAQ
IFAEDQDMVESQKPEELPLDISMEAHFEADRSSTTYRRILAEWGLSKRYIV
>A0A0H2M175|methylxanthine N1-demethylase|EC 1.14.13.178|Variovorax paradoxus|TrEMBL
MSTDSISTWHPVARSAELRPGANIVAGFAEGQELALWRSASGAAQAWENRCPHRSVRFTL
GQVVEDRLSCAYHGWQYDAGSGQCAGIPAHPGMPVPRNVCAKVFSAAEASGMLWVSLTPA
APSSPPPDDAVPAGWSFCRTLCVRAGAASVRDALAARGFTADAPSRGLRGALDHVDAAAL
VLDAQPHLAFIHLWTPAAPGSAAMKTLHIAVRALRGEIEVRQQAA
>A0A181CCR3|methylxanthine N1-demethylase|EC 1.14.13.178|Komagataeibacter rhaeticus|TrEMBL
MSPSMHAPDTLPRNCTFEPDDWAILARFWYPVALERDVGDRPVAAMLLDEPLVVYRAGED
IVIAHDLCPHRGVPLSLGSGDGGSIACAYHGFRFGAAGRCVRIPAHPDHAIPSKMHLRTY
PAIRRYGLIWTCLRPDGQWPDDATAIMANADIPLMPHWQDAGFQQIVCPSIDIHGFAGRQ
MEGFLDVAHFAFVHTATFADPDNPVVPGYRPVRTDRGFEVEYRSTVGNYPIGRVDHGRPG
FEWLRHFRTHLPFTATLTVHFPDDGRLVIMNAASPVSARETRLFAPICRNFDTDLPVQDV
YDFNRRVFEEDKAIVEAQKPECLPLDPRLEAHVPADRSSIAYRRGLRELGLSRFFIS
>A0A6J5FTX0|methylxanthine N1-demethylase|EC 1.14.13.178|Paraburkholderia fynbosensis|TrEMBL
MLVTRQRVLRRFWYAIMPMAKLDEGPQPFTLLGEPIVLWKGAGGKPHALRDRCCHRTARL
SKGFVDGDGNIACGYHGWTYDCSGQCVKIPQNNGTAIPSRAVVQAYRCEERYGYAWVALD
EPLQPIPEFPEETAPGYRRILQFYERWETSPLRMMENSFDNSHFSFVHKSNFGLFDNPKP
SKYEFRPNEWGFEAQTHVPVRNPPASHRVTGTVEEVTERHLTNRWFMPFARRFGCVYPAS
GVHHIIYNCATPIDDRTLMLSQWLYRNDSEEACSTQELIDWDRPITDEDRDILEATDYDA
CIDVRRQQECHMESDQPGLLMRRMLLKLLNDHGESEVFRVETEA
>A0A5B7V449|methylxanthine N1-demethylase|EC 1.14.13.178|Streptomyces sp. YIM 121038|TrEMBL
MIPNQWYPILRTKDVKRDAPTGVKRLGEELVLWRDLSGTLVCQSARCPHKGANLSDGRVV
GNSLACPYHGFRYDAGGACRLIPALGTEGRIPASLRIDTYEVREKYGLVWLWWGEKREEL
PDIELPHELAEHPRPYETITWSRPVHYTRYIESLLEFYHVTFVHRDHWANIIDYTFMYGS
WRKLWTDGRERYIAANKIVNHRVDVDGTIIRSTFDQCEEGNPSNIWHFDLIYQAPCMTHV
RQGLLEVTTWLTPIDEENTQAIMRLWEYPLLKRMVPVKALRPLVLKASLQMEKYVQDQQD
NDIMARQEPKVSERGVNKLIAPDEMNAKYLQLRDRLKAEARADAEARAAERAREAAAADP
AAPAPTAGGNGSSFANGTSPANGTSATNGSSPGQAPAAARPEKAAARAGGVSESAP
>A0A1D8G7P3|methylxanthine N1-demethylase|EC 1.14.13.178|Streptomyces rubrolavendulae|TrEMBL
MDPVEYEMLRHMWFPVARVADLKNGVASGSILGEELVVYGDEGSVTVAQGFCPHRGVALR
LGQLRDGALECPYHGWLFETGSGRCARIPSLPPGRGRPHTALRTYPAEVAYGLVWSCLGD
PFLPLPRLPEYVDNSWQLGAGEPYTLNCGMRLLTENFRDKAHFPFVHADSMGHVDKVVEP
YRITRDGWRLGWSSSLGSEGVPEDMAEEFRHRLDYHITMPVFASICVSSPSGGRRLVAQV
ATPVSADGKTVRQFWLAGTDAESATQGAVLADVLGFERQVFEEDHPIVENQWPVEAPLDV
HSQVHTPADRFSITYRKVYGELLENFKESQ
>A0A1S1V6M8|methylxanthine N1-demethylase|EC 1.14.13.178|Andreesenia angusta|TrEMBL
MIKSQWYAVLDSKEVKKGRLTGATRMSQKLVFWRDSGGQIHCIFDKCCHRGASLSAGKLV
DGAVECPFHGFQYETTGKVVLIPANGMNAEVPDNFKVNSYLAKEAYGLVWIWYGEDRENV
PEIPFFQELKSGFFYGGFSETWPVHYSRAIENQLDVVHLPFVHKTTIGRGNRTLVNGPVV
KWQDNLMTFYVKNQTDRGQSPEKPGEILDYEKLFSLQFQMPNLWQNVISPNFRIVAIFAP
IDEENTHIYIRSYRKGKLPLLFNWISDFVGNVGNKVILHQDRRVVITQIPKKTELSMKEN
LIQGDLPIIEYRKRREKLKSKSERQRDC
>A0A346BIK8|methylxanthine N1-demethylase|EC 1.14.13.178|Paraburkholderia caffeinilytica|TrEMBL
MSSATATAAVTATAAPLTFQRSPALPRNCTFDSHDWEILSRYWHPVAFAADVTDKPISVT
LLDEPLVVFRSNGQLVSARDICPHRGAPLSQGWVDNGGIVCPYHGLAYGSDGKCKHIPSQ
TDGPIPERLHLVTYATQEAYGLVWVSLGGGTEALPAFPNWDDPDFQQILPPSIDINASAG
RQTEGFIDVAHFAWIHHDSFADRHNPVVPQYSVERRERGMHAEYVSTVSNFPKSMQHRAP
EGYLWHRFFDVDVPFFARLTVHFPDNGRLSILNAASPVSARKTRLFVPIVRNFDKDLPLE
DVYAFNRQVFEEDRAIVEQQRPEDLPIDRAAEAPILADRSSGAYRRALAEIGLGQAYVR
>A0A2J7VAK1|methylxanthine N1-demethylase|EC 1.14.13.178|Variovorax sp. B4|TrEMBL
MIERELWHPVALAGEIAQAPFAVQLLGESLVLWRDAAGAVQAWADRCPHRGAQLSLGRVC
DGGATLECPYHGWRFASGGRSVYVPALPDFVPPATHRATVHAAQEAYGLVWVRLEGEGGE
LPAFPAEHDARLRKLDCGPYEVQTSAPRLVENFLDMAHFGFVHEGWLGAREMTVIGDYRV
EATPRGLLATGCKAWQPQSTINSTAPALVEYRYEVTAPYAAVLTKVPEAASVGIEGYQES
IALFICPMEPERCRVWFRFATADFERDDAQLRAFQDTIFLQDKPVLESQRPRSLPLDLHA
ELHTAADKASSFYRRHLRARGITFGVC
>A0A5K6CVM1|methylxanthine N1-demethylase|EC 1.14.13.178|Acinetobacter baumannii (strain AB307-0294)|TrEMBL
MNAIPTLTPLAMPCNSSFEAKDWEILSTHWYPVARIQDVSNAPQRVTLLDVNMALYKTES
GEIHLVRDICPHRGVPLTKGWVDGEEIVCPYHGLRYNAEGKCTQIPAQPELTKISDRFSL
TKFPVVQRYGLIWTSIHGRDVTQANIPVLDTWDDAEHQAILPPFVDIGGSSGRQLEGFID
VAHFAWVHHNAFANRDNPVVPKYHTERTNYGLKTVYISNVSNYPHELKHLEPEGFLWKRT
FEVYPPFSAVLTVDFPEGGILKILNACCPISSNKTRLFVPLTRNFDQTGDLEKVYAFNAQ
IFAEDQDMVESQKPEELPLDLMMEAHFEADRSSTTYRRILAEWGLSKRYTV
>A0A347WG69|methylxanthine N1-demethylase|EC 1.14.13.178|Komagataeibacter saccharivorans|TrEMBL
MTTATCARPADIHPLPRTMTFEVDDWNILARCWHPVALVRELGDRPLGVTLLDAPLVVYR
AGDSIVVADDLCPHRGVPLSMGKGDGQTVACAYHGFRFGEKGRCVKVPAHPDSAIPSKLN
LRTYPAVERYGLIWTCLRPEGDGADIPPMPHWNDPAFQQINCPWIDIAGFAGRQVEGFID
VAHFAFVHTDTFADPENPVVPPYRTRITPDGFEAEYRSSVGNYPIGKSDRGRPGFEWLRH
FRVHVPFTATLEIHFPDNGRLVIMNAASPVSARKTRMFAPMCRNFDKDLPLQDVYDFNLR
VFEEDRALVEAQKPENLPLDPTLEAHVMADRSSIAYRRALRTMGLSQFFTA
>A0A6J5GC38|methylxanthine N1-demethylase|EC 1.14.13.178|Paraburkholderia caffeinitolerans|TrEMBL
MTQPQVAVLTRAGKPAMPRNCTFDARDWEILSRYWHPVAFAGEVRDKPLAVTLLDEPLVV
FRSGDRIVAARDVCPHRGAPLSRGWVHNGNLVCPYHGLEYAANGKCNYIPSQPEGLIPER
LCLTTYAAQEAYGLVWVSLGGGELPLPDFPAWNTDGYQQILPPSIDIRASAGRQTEGFID
VAHFAWIHHDSFADRRNPVVPQYSVERRPNGLRAEYVSTVSNFPKSMQQRAPEGFLWRRI
FEVDVPFFARLTVHFPESGRLAILNAASPVSARHTRLFVPIARNFDHDLPLDDVYAFNRQ
VFEEDRAIVELQCPEDLPIDRSQEAPILADRSSGAYRRSLAEIGLGQSYVR
>A0A7K0D582|methylxanthine N1-demethylase|EC 1.14.13.178|Nocardia macrotermitis|TrEMBL
MLKNFWYALEFADKVGRTPRQVRCLGQDFVLYRTESGEPICLSDLCVHRGGALSMGTVSG
DCITCPYHGWQYDSNGVCVRIPANAPERAIPRKARVDAYPAVERYGMVWAFLGDLPEEQR
PPIPEIPQWADPSFRAVQYEMVVDANYERTFENVVDASHTPFVHGTAFGNPDKPEIPDFR
VRQTDWSAEADIPLSPPPPKGLWGLLFRGKELPDFVTVTNAWYLPNIVKLHVRLPIGDLM
LYDFNIPLSQDRTLIKILGFRNFFTGGWADGNTRKRIEKILLQDRPVVESQRPELLPFDL
SDELHVRSDALQVAYRRRRAQLIKDGWWVGGDDVVTGDSPRRRATVLASPARHDNPELAA
AWVHKARQGGDPR
>A0A2N7RU24|methylxanthine N1-demethylase|EC 1.14.13.178|Janthinobacterium sp. AD80|TrEMBL
MPGYALEELFNTSVFPLRTGCRLADNRGMQLAQDQWYPVLDSVELKKQPLGAQRLGRRLV
FWRTADGKPHAHPDRCPHLGTALSAGSIHGNRLVCPFHGFAFDGDGRCGHIPANGCARKV
PKAMAVDSFPLAEAHGFIWLWLGQTRESYPPLPFFEQLQQGWQYRTEIVDWPVHYTRAIE
NQLDVAHLAFVHRSTIGRGGRSFVDGPYVEADAQGIRVWTSNAPDQGQEHRSQAELAQAA
QGREPSLQLLFPGTWLLNITPGLRNFIAFVPINEHTVRYYLRFYHRVRVPGLAWLFGRLM
GWSNRIVLNQDRRVVVTQTPANSLDAMDDRFIEADRAIIAYRKQLARLLQNK
>A0A181CDL9|methylxanthine N1-demethylase|EC 1.14.13.178|Komagataeibacter rhaeticus|TrEMBL
MERWHPVSVLSDLHRGEVAGVRIDGHEVVLWREDTDSATLHAWEDRCPHRGMRLSFGFVR
EGALGCLYHGWQFGGTARCRLIPAHPNVRVPAAIQVRTHMVREHAGLAWVGMDGAGAFPA
TMPVPWPVVQPVRSVHVSAGAGLLRHALGMHADVAMTWRGPVGLAVHAPVAGQAMLHVVR
ARDAQAPSPLVLSRWAERLRDGVEGGGDTTRIMGELA
>A0A1X7A4S7|methylxanthine N1-demethylase|EC 1.14.13.178|Roseovarius albus|TrEMBL
MFQSVNHSKFAGDLPRNCTFAESDWRILASMWHPVAFAHEIEDKPVKARLLDVDLVVYRT
SQGVSVARDICPHRGTRLSGGWVKDDALVCPMHGLNFDHAGACTKIPCIGDPNVKIPPKL
RLMSIMSEERYGIIFACLSGEPSHPLPIWEGVSDDTLEKIFIPSGTWNAAASRHVENFND
VAHFPWVHKETFGGYEADPIPPYKVNKTDYGLSFDLPYLEQGNRFPDGIEADDRQVTYHY
ELTLPFSTLLVIGPDDSDYRQYFADTVCPVSAHETRIFQVVTDTTGKPDHDFLVKESLQI
NDEDKPMVEGQHPEDLPLDLTEEIHIPADRMSVEYRRALAKLGLGAPIAS
>A0A5E6MFD4|methylxanthine N1-demethylase|EC 1.14.13.178|Methylacidimicrobium tartarophylax|TrEMBL
MTASSFENPPPSPALLEAYLRAMAPFWHPLCPVAALGREPMPIELLGKRLAIVCLDGRIA
VFSDLCPHLGAALSLGSVVKGRHLRCPYHGWSFDGMGRCVDIPARKGLSIPAATRAETFP
STEAHGLIWACLAPPARSPIPDFPELSDPQFHLGPWKEGSTWRASAPRVILSQLDDTHFC
WVHPGTIGSATHPETPDHKVSRTASTVVSRFTVWQRAEAPSVGLGSATAEKDPLPVSYVI
EAGTSSVHIRKQRKEAAFAVFQAVSPVRHDRCRVFWRIARTYDKKTESDPVHDRVQDAIL
EEDRKVVESQRPWLLPPISAGRIRYLGPCDLPLVEYHRWMEELGVPQL
>A0A5E7SMB9|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas fluorescens|TrEMBL
MLTNLWYVVLPSSQLTDGLMPVQLLGQPFVAFRDDAGVAHLLSDICVHRGGSLSAGSKVG
NSVQCPYHGWRFGGDGVCTQIPAQPDLRIPAKARVDAYPTLERYGWIWAFLGDLPESERP
PLPTLDWVDDPAIRVVSGHFDWQASWDRIIENGLDFAHAPFVHGSTFGDPDHPEIESFEV
DSDAWSGSAQMLMRRPARKGLLRRKSSTEFVSVATVPGFHLSGPCTTLELELPNGWRIYI
VSAHVPIDANRTRTWWMMGRTFLRTRLLDRRFIASNIRIFEQDHAVLKNVRPERVPDSFQ
QEVSLKSDALQIAFRRDVQALEQRGWRIDEERLARTFTGRKACAIPSPERRQIRAWAIEP
IPLVDITHESE
>A0A181C560|methylxanthine N1-demethylase|EC 1.14.13.178|Komagataeibacter rhaeticus|TrEMBL
MLATQEPRLRDFWYCLFPMHELSDAPRAFRLLGQDIVVWRDEDGRPHAVIDRCPHRSARL
SGGTVEEGRIVCPYHGWAFRGDGRCVSVPQSVTNAGPQFGVKALHCTERYGQVWVCPGEP
AFDLPHVPHFEKPGYRQIFEFSEDWACSAQRIIENEFDTAHFSFVHKGSFGDSDPAPART
DITETETGFVAELHFAVRNPEDMRDALQMHDDNTVRNVISRFIMPFYQIAEINYPNGLTN
VLVTWLTPVDDGTTRFNQFVMRNDREEDVPASQVRAFDRRITSEDRQVLELTDPMVPLDT
SEGVEIHMASDKPGLIMRRRMREFLHGGKKA
>A0A347WFI7|methylxanthine N1-demethylase|EC 1.14.13.178|Komagataeibacter saccharivorans|TrEMBL
MPAFPETLPTVCEDEALLNDWFPVGYSSDFEKGKIAPVRLLDRDLIAWRDDAGEIHVWED
LCIHRGARLSKGCIRDNQVVCPYHGWRYNSRGECTLIPAAPRETPMRKARAFSHHVAERY
GFVWTCLGDNPGEIAPFPEWDDERFQKVLCGPYPYNANGYRAVENFVDATHFPFVHAGLN
GVMENPDEIAPYTVEIGDEGVVSSEVRVFQPWGDARGIPVVGFYTYKCLRPLLARFSKRV
LKADENGTPVDNNSEYFATLFTVQPLSATECIVRICSATDLQPAPTAEAVRERADVVFNQ
DRVIVETQRPERIPTHLRYELHHRTDLMGQKYRTWLRSLGITYGTI
>A0A402DDB6|methylxanthine N1-demethylase|EC 1.14.13.178|Microcystis aeruginosa NIES-4285|TrEMBL
MTSTDQSQPLPRDDYFHYQNCWYPVLFVQDWQKNPYSFSLYGQPLLIFRDQQGKWGCLLD
RCPHRLAKLSTGQMIAGRLECLYHGWQFETDGKCSHIPQLPVNTPIPRNAKVKSYGVVER
QGVLWIWLGEEETAKESDIPIIKDLEDPNCVHTDYLIDFPYEQGYLLENLLDPAHVNISH
DRSEFGAKRENAQPLAFQILEISARGIRSQWRNSRNPQESWKYLDFIAPNLVHYRFSLPN
PHWCAGLALYGISLGQGRSRLLVRRYQNFAVNSRQYRWRWLEHLRQSRILEDDLPLIQSQ
QQMVEKSRDSLQKLYLPLKSSDALVIELRQWFDRYGDSFPYYQGYTSQRTTAIDLSDPLP
LDRYSRHTVHCRTCSAAHENMVKTKQIAILMGILLALLAILSPNQSIYQITALIFAILAL
AIAIAANYTRTKFERTHEKKAHTKLQ
>A0A554WR76|methylxanthine N1-demethylase|EC 1.14.13.178|Tepidimonas sediminis|TrEMBL
MLVTRQPVFRRHWYAVMPLSALRDGPRPFTLLGENIVLFLDADGQPAALQDRCCHRTARL
SKGWCKGGGLQCGYHGWVYDREGRVVEIPQYEPGREIPAHYRTRAYRCTARYGYAWVALE
EPQLDIPPMPEFDAPGWRTIFQFYETWHTSPVRALENSFDNAHFSFVHRATFGVAERPQP
SRYQIVENERGFYAETVIEAANPERFRRISGVNEPITTRHMRNAYLRPFARRLDIEYPSG
VRHVILNCFTPIDDGRIQLCQWLFRNDTEEDCPAQLLTEFDYEITREDKDILESTDPDAV
VDLQRRGVEYSMDSDRPGILIRRQLMQMLTEAGETEVHRGLAAA
>A0A554WRA8|methylxanthine N1-demethylase|EC 1.14.13.178|Tepidimonas sediminis|TrEMBL
MIERDHWWPVALDGDVGAAPLPVALLGEPLVLWRDGAGAVQAFADRCPHRGARLSLGAVV
GGQLQCPYHGWRFDGDGRCRAIPALPGFAPPVSHAAYRHAVVSAHGLLWVCLGTPAAPAP
PALPPLPPRRVVHGPFDVATSAPRAIENFLDTAHFAWVHDGWLGAPTHAEVPPYEVTLTA
DGRPVVPDYPAWQPRATASAQGGAWVRYRYEVLSPFAALLQKQPEGDAPADAYVMWTCPS
TPETCRVWFVQHTTDTITPDEALRDFQSAIFAQDRPILESQTPKRLPLSGGEAMCAADRL
SAAYRRYLRAAGVTFGVC
>A0A2S9YN06|methylxanthine N1-demethylase|EC 1.14.13.178|Enhygromyxa salina|TrEMBL
MIPNEWYAVFEANKLGRKPVGIKRLGEELVLWRDAAGNAVGMVNRCPHRGAKLHLGTVSQ
GCIQCPYHGFLFDSRGACRYVPANGGERAIPKGLHAKAWPVREKHGLIWLFWGDAREHYP
EIPWFPQAPEDDANSSQQSALYDFHYARAIENAMDAHHFPCIHGAIAPNCGFAVDPMEAE
WDGEEIRVTAGLKRHMDEPDEDAVMFRMKFKFPNIFYVDLTDSVWLIQVATPVDEHTTWG
FVRYYQRFVTLPKIGPLISGALMRFDAVLAQNVQDVPVFSTQTPHKPGLDAGYKLIKADR
GIYYYLSERERRIKAAKEQQQAKAALEAEAAT
>A0A5E6UFM1|methylxanthine N1-demethylase|EC 1.14.13.178|Pseudomonas fluorescens|TrEMBL
MLTNLWYVVVPSSQLTDGLMPVQLLGQPFVAFRDDAGVAHLLSDICVHRGGSLSAGSKVG
NSVQCPYHGWRFGGDGVCTQIPAQPDLRIPAKARVDAYPTLERYGWIWAFLGDLPEYERP
PLPALDWMDDPAIRVVSGHFDWQASWDRIIENGLDFAHAPFVHGSTFGDPDHPEIESFEV
DSDAWSGSAQMLMRRPARKGLLRRKSSTEFVSVTTVPGFHLSGPCTTLELELPNGWRIYI
VSAHVPIDANRTRTWWMMGRTFLRSRLLDRRFIASNIRIFEQDHAVLKNVRPERVPDSFQ
QEVSLKSDALQIAFRKDVQALEMRGWRIDEERLARRFTGRKACAIPSPERRQIRAWAIEP
IPLVDITHESE