>Q3ZBV9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bos taurus|Swiss-Prot
MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLI
PYRCDLSNEEDILSMFSAVRSQHSGVDICINNAGLARPDTLLSGSTSGWKEMFNVNVLAL
SICTREACQSMRERKVDDGHIININSMCGHRVPPPAETHFYSATKYAVTALTEGLRQELR
EARSHIRATCISPGVVETQFAFKLHDKDPEKAAATYEHMKCLKPEDVAEAVIYVLSTPPH
VQIGDIQMRPTEQVT
>Q71R50|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Gallus gallus|Swiss-Prot
MERWTGRVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKIEKLAAECQSAGYPGTLI
PYKCDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVMAV
SICTREAYQSMKERNIDDGHIININSMNGHSVVPQSVVHFYSATKYAVTALTEGLRQELR
EAKTHIRATCISPGLVETGFAFKLHDNDPERAAATYESIRCLKAEDMANAVIYVLSAPPH
VQIGDIQMRPTEQIS
>Q6UWP2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MARPGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGY
PGTLIPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNV
NVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGL
RQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVL
STPAHIQIGDIQMRPTEQVT
>Q3U0B3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus musculus|Swiss-Prot
MTRAGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGY
PGTLIPYRCDLSNEEDILSMFSAVRSQHSGVDICINNAGMARPDTLLSGSTSGWKDMFNV
NVLALSICTREAYQSMKERNIDDGHIININSMCGHRVPPQSVIHFYSATKYAVTALTEGL
RQELLEAQTHIRATCISPGLVETQFAFKLHDKDPGEAAATYEHIKCLRPEDVAEAVIYVL
STPPHVQVGDIQMRPTEQVT
>Q3T001|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bos taurus|Swiss-Prot
MWLYLAVLLGLYYLLRWFRERQVVSHLQDKFVFITGCDSGFGNQLARQLDLRGLRVLAGC
LTEQGAEQLRNQTSDRLQTVILDVTKTESIAAATEWVKECVGDRGLWGLVNNAGIFHSHG
YAEWIKIETYRDTLRVNLIGVIEVTLSMLPLVRKAQGRIVNVSSILGRIAFFGAVYSCSK
YGVEAFSDILRRELQHFGVKVSMVEPGYFRTAMTDWQKFSEIMKQIWKETPAHIKETYGQ
KFFDAYHDLMKQGLLSCSTNLNLVTDCMEHALTSVHPRTRYSAGWDAQFFFVPLSYLPTS
LADYILTRSWPKPAQAV
>O14756|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC
LTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPIT
LCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSK
YGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQSWKEAPKHIKETYGQ
QYFDALYNIMKEGLLNCSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYLPTS
LADYILTRSWPKPAQAV
>O02691|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bos taurus|Swiss-Prot
MAAACRSVKGLVALITGGASGLGLATAERLVGQGATAVLLDLPNSDGETQAKKLGKSCAF
APADVTSEKDVQAALTLAREKFGRVDVAVNCAGIAVASKTYNLKKSQAHTLEDFQRVINV
NLIGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL
PIARDLAPMGIRVMTIAPGLFGTPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQAI
IENSFLNGEVIRLDGAIRMQP
>O18404|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|Swiss-Prot
MIKNAVSLVTGGASGLGRATAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVT
SEKDVSAALQTAKDKFGRLDLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTF
NVIRLSAGLMGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDL
STQGIRICTIAPGLFNTPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLL
NGEVIRIDGALRMMP
>Q99714|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVF
APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV
NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL
PIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAI
IENPFLNGEVIRLDGAIRMQP
>O08756|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus musculus|Swiss-Prot
MAAAVRSVKGLVAVVTGGASGPWLATAKRLVGQGATAVLLDVPDSEGESQAKKLGESCIF
APANVTSEKEIQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHQKKNKIHTLEDFQRVINV
NLIGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIDGMTL
PIARDLAPTGIRVVTIAPGLFATPLLTTLPEKVRNFLASQVPFPSRLGDPAEYAHLVQTI
IENPFLNGEVIRLDGAIRMQP
>O70351|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rattus norvegicus|Swiss-Prot
MAAAVRSVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIF
APANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINV
NLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTL
PIARDLAPIGIRVVTIAPGLFATPLLTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMV
IENPFLNGEVIRLDGAIRMQP
>Q04828|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
RNVRYLTLDIFAGPPNYPFSDEY
>Q95JH7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Macaca fascicularis|Swiss-Prot
MDSKHQCVKLNDGHFMPVLGFGTYAPAEVPKNKALEATKLAIEAGFRHIDSAHLYNNEEY
VGLAIRSKIADGTVKREDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPV
SLKPGEELIPKDENGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
GLKYKPVCNQVECHPYLNQRKLLDFCKSKDIVLVAFSALGSHREKPWVDQNSPVLLEDPV
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENMKVFEFQLTSEDMKAIDGLD
RNIRYLTLDIFAGPPNYPFSDEY
>Q95JH6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Macaca fuscata fuscata|Swiss-Prot
MDSKHQCVKLNDGHFMPVLGFGTYAPAEVPKNKAIEATKLAIEAGFRHIDSAHLYNNEEY
VGLAIRSKIADGTVKREDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPV
SLKPGEELIPKDENGKLLFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
GLKYKPVCNQVECHPYLNQRKLLDFCKSKDIVLVAYSALGSHREKPWVDQNSPVLLEDPV
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENMKVFEFQLTSEDMKAIDGLD
RNIRYLTLDIFAGPPNYPFSDEY
>Q5REQ0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pongo abelii|Swiss-Prot
MDSKYQCVKLNDSHFMPVLGFGTYAPPEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLVHFPV
SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEKWVDPNSPVLLEDPV
LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRQNMQVFDFQLTSEDMKTIDGLN
RNMRYLTLDIFAGPPNYPFSDEY
>P52895|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP
GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
RNVRYLTLDIFAGPPNYPFSDEY
>P42330|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD
RNLHYFNSDSFASHPNYPYSDEY
>Q5R7C9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pongo abelii|Swiss-Prot
MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEECKDAGLAKSIGVSNFNRRQLEMILNKP
GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTAEDMRAIDGLN
RNLHYFNSDSLASHPNYPYSDEY
>P17516|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM
ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP
GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV
LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN
RNYRYVVMDFLMDHPDYPFSDEY
>Q95JH5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Macaca fascicularis|Swiss-Prot
MDPKYQRVALNDGHFMPVLGFGTYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPM
ALKPGETPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNP
GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPV
LCALAKKHKRSPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSEDMKVLDDLN
RNFRYVVMDFLVDHPDYPFSDEY
>Q95JH4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Macaca fuscata fuscata|Swiss-Prot
MDPKYQRVALNDGHFMPVLGFGSYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPM
ALKPGETPLPKDENGKVMFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNP
GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPV
LCALAKKHKRSPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSEDMKVLDDLN
RNFRYVVMDFLVDHPDYPFSDEY
>P56937|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV
QVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTA
EGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFS
LEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYGILPPFIW
TLLMPAILLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTGFGRNYIMTQ
KMDLDEDTAEKFYQKLLELEKHIRVTIQKTDNQARLSGSCL
>O88736|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus musculus|Swiss-Prot
MRKVVLITGASSGIGLALCGRLLAEDDDLHLCLACRNLSKARAVRDTLLASHPSAEVSIV
QMDVSSLQSVVRGAEEVKQKFQRLDYLYLNAGILPNPQFNLKAFFCGIFSRNVIHMFTTA
EGILTQNDSVTADGLQEVFETNLFGHFILIRELEPLLCHADNPSQLIWTSSRNAKKANFS
LEDIQHSKGPEPYSSSKYATDLLNVALNRNFNQKGLYSSVMCPGVVMTNMTYGILPPFIW
TLLLPIMWLLRFFVNALTVTPYNGAEALVWLFHQKPESLNPLTKYASATSGFGTNYVTGQ
KMDIDEDTAEKFYEVLLELEKRVRTTVQKSDHPS
>Q62904|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rattus norvegicus|Swiss-Prot
MRKVVLITGASSGIGLALCGRLLAEDDDLHLCLACRNLSKAGAVRDALLASHPSAEVSIV
QMDVSNLQSVVRGAEEVKRRFQRLDYLYLNAGIMPNPQLNLKAFFCGIFSRNVIHMFSTA
EGLLTQNDKITADGFQEVFETNLFGHFILIRELEPLLCHSDNPSQLIWTSSRNAKKSNFS
LEDIQHAKGQEPYSSSKYATDLLNVALNRNFNQKGLYSSVTCPGVVMTNLTYGILPPFVW
TLLLPVIWLLRFFAHAFTVTPYNGAEALVWLFHQKPESLNPLTKYLSGTTGLGTNYVKGQ
KMDVDEDTAEKFYKTLLELEKQVRITIQKSDHHS
>Q9GME3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Callithrix jacchus|Swiss-Prot
DWDKVIAVNLKGTFLVTQAAGQALVSSGCSGSIINISSIVGKVGNMGQTNYAASKAGVIG
LTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVMNKITGMIPMGHLGDPEDVADVVA
FLASEDSGYITGAS
>Q5TJF5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Canis lupus familiaris|Swiss-Prot
MASPLRLRSALALVTGAGSGIGRAVSVRLAKEGATVAACDLDRAAACETVWLLGGQGSEK
VAPGGAHTAFQADVSEAGAVRRLLEQVQACFSRPPSVVVSCAGLTRDEFLLRMSEDDWDR
VIAVNLKGIFLVTQAAAQALVSSGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQT
AARELGRHGIRCNSVLPGFITTPMTQKVPQKVLDKVIGMIPMGHLGDPEDVADAVTFLAS
EDSGYITGASVEVTGGLYM
>Q92506|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGS
KEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDW
DKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLT
QTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFL
ASEDSGYITGTSVEVTGGLFM
>P50171|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus musculus|Swiss-Prot
MASQLRLRSALALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSPGSED
GAPRGKHAAFQADVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDR
VIAVNLKGTFLVTQAAAQALVSSGGRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQT
AARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIPLGHMGDPEDVADVVAFLAS
EDSGYITGASVEVSGGLFM
>Q9XT00|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sus scrofa|Swiss-Prot
MASQLRLRSALALVTGAGSGIGRAVSVRLAAEGAAVAACDLDGAAAQETVQLLGGPGSEK
GAPSGPMAAFQADVSEAETARRLLEQVQAYFFRPPSVVVSCAGITRDEFLLRMSEDDWDK
VIAVNLKGIFLVTQAAAQALVSSGCPGSIINISSIIGKVGNMGQTNYAASKAGVIGLTQA
VARELGRYRIRCNSVLPGFIKTPMAQKVPQKVLDKVVGMIPMGHLGGPPDVADVVAFLAS
EDSGYITGASVEVTGGLFM
>Q6MGB5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rattus norvegicus|Swiss-Prot
MASQLRLRSALALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGNPGSED
REPRGKHAAFQADVSEGPAAKRLLEQVQACFFRPPSVVVSCAGITRDEFLLHMSEEDWDR
VIAVNLKGTFLVTQAAAQALVSSGGRGSIINISSIVGKVGNIGQTNYASSKAGVIGLTQT
AARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIPLGHMGDPEDVADVVAFLAS
EDSGYITGASVEVSGGLFM
>Q4R5G7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Macaca fascicularis|Swiss-Prot
MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGGTD
GIGKSYAEELAKRGMKVVLISRSQDKLDQVSSEIKEKFKVETRTIAVDFTLEDIYDKIKT
GLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERS
KGAILNISSGSGMFPVPLLTIYSATKTFVDFFSQCLHEEYRSKGIFVQSVLPYFVATKLA
KIRKPTLDKPTPETFVKSAIKTVGLQSRTNGYLIHVLMGWIISNLPSWIYLKIAMNMNKA
TRVHYLKKIKKN
>O70503|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus musculus|Swiss-Prot
MECAPPAAGFLYWVGASTIAYLALRASYSLFRAFQVWCVGNEALVGPRLGEWAVVTGGTD
GIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDDIYDKIKT
GLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERS
KGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMPYLVATKLA
KIQKPTLDKPSAETFVKSAIKTVGLQTRTTGYVIHSLMGSINSIMPRWMYFKIIMGFSKS
LRNRYLKKRKKN
>Q6P7R8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rattus norvegicus|Swiss-Prot
MERALPAAGFLYWVGASTIAYLTLRASYSLFRAFQVWCVGNQAFVGPRLGEWAVVTGGTD
GIGKSYAEELAKRGMKIVLISRSQDKLKEVSNNIKEKFNVETRTIAVDFSLDDIYDKIKT
GLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSICKVTRLVLPGMVERS
KGVILNISSASGMLPVPLLTVYSATKAFVDFFSQCLHEEYKSKGIFVQSVLPFFVATKLA
KIRKPTLDKPSAETFVKSAIKTVGLQTRTTGYVIHAIMGSINSILPRWIYFKTIMGFNKS
LRNRYLKKTKKN
>Q28IU1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xenopus tropicalis|Swiss-Prot
MATESLAEVPVPGCNCFWYLGVVAAVWWGLRAAWCLLDGARVWVLGSGAQVGPRIGKWAV
VTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTE
IYGRIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENTLDKMININITSVCQMTRLVL
PGMLGRGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKGVTVQSVLPF
YVATKLAKIRKPTWDKPSPETYVQSALNTVGLQTQTNGYLPHAIMGWISTSLVPVSTAIS
LGMKMNKGLRARFLKRAKQK
>Q9MYP6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bos taurus|Swiss-Prot
MAMGTRYAGKVVIVTGGGRGIGAGIVRAFVESGAQVVICDKDEARGRAVERELPGTVFLL
CDVTREEDVRTLVSETIRRFGRLDCIVNNAGYHPPPQWPEETSAQGFRQLLELNLLGTYT
LTKLALPHLRKSRGNVINISSLVGAIGQSQAVPYVATKGAVTAMTKALALDESQYGVRVN
CISPGNIWTPLWEELAASTPDPTATIREGTLAQPLGRMGQPAEVAAAAVFLASEATFCTG
TELLVTGGAELGYGRKAGQAAPAEAPTTPS
>Q9BPX1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFIL
CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYT
LTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVN
CISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTG
IELLVTGGAELGYGCKASRSTPVDAPDIPS
>P14061|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV
RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG
GAGPGAEDEAGRGAVGDPELGDPPAAPQ
>P51656|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus musculus|Swiss-Prot
MDPTVVLITGCSSGIGMHLAVRLASDRSQSFKVYATLRDLKAQGPLLEAARTQGCPPGSL
EILELDVRDSKSVAAAQACVTEGRVDVLVCNAGRGLFGPLEAHELNAVGAVLDVNVLGTI
RMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAILLPLFGVH
VSLIECGAVHTAFYEKLVGGPGGALERADAQTRHLFAHYLRGYEQALSEAQDPEEVTELF
LTAMRAPQPALRYFSTNRFLPLARMRTEDPSGSSYVAAMHQEAFSNLQTQENAKAGAQVP
GVSDTASSALICLPECAIPRVASELGWSASDKPGQDNSCYQQKI
>Q1WNP0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pan troglodytes|Swiss-Prot
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG
GAGPGAEDEAGPSAVGDPELGDPPAAPQ
>P51657|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rattus norvegicus|Swiss-Prot
MDSTVVLITGCSSGIGLHLAVRLASDRSQSFKVYATLRDLKSQGPLLEAARAQGCPPGSL
EILELDVRDSESVAAARACVTEGRVDVLVCNAGRGLFGPLEAHELNAVGAVLDVNVLGTI
RMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAILLPLFGVH
VSLIECGAVHTAFHEKLEGGPGGALERADAQTRHLFAHYQRGYEQALSEAQDPEEVTELF
LTAMRAPQPALRYFSTNRFLPLARMRTEDPSGSSYVEAMHREAFSDLQVQEGAKAGAQVS
GDPDTPPRALICLPECAIPRVTAELGWSASDKPGQNKSCYQQKI
>P37059|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MSTFFSDTAWICLAVPTVLCGTVFCKYKKSSGQLWSWMVCLAGLCAVCLLILSPFWGLIL
FSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPG
AEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELL
LMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVT
MFSSVMRLELSKWGIKVASIQPGGFLTNIAGTSDKWEKLEKDILDHLPAEVQEDYGQDYI
LAQRNFLLLINSLASKDFSPVLRDIQHAILAKSPFAYYTPGKGAYLWICLAHYLPIGIYD
YFAKRHFGQDKPMPRALRMPNYKKKAT
>P51658|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus musculus|Swiss-Prot
MSPFASESAWLCLAAAAVLGGTLLCGCRSGRQLRSQAVCLAGLWGGACLLSLSLLCTLFL
LSVACFLLLYMSSSDQDLLPVDQKAVLVTGADSGFGHGLAKHLDKLGFTVFAGVLDKEGP
GAEELRKHCSERLSVLQMDVTKPEQIKDAHSKVTEKIQDKGLWAVVNNAGVFHLPIDGEL
IPMSIYRKCMAVNFFGTVEVTKAFLPLLRKSKGRLVNVSSMGGTVPLQMTSAYAATKAAL
TMFSTIIRQELDKWGVKVVTIKPGGFKTNITGSQDIWDKMEKEILDHFSKDIQENYGQDY
VHTQKLIIPTLKERSNPDITPVLRDIQHAISARNPSSFYYPGRMAYLWVCLAAYCPTSLL
DYVIKKGFYPQPTPRALRTVH
>Q62730|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rattus norvegicus|Swiss-Prot
MNPFSSESAWLCLTATAVLGGMLLCKAWSSGQLRSQVVCLAGLWGGACLLSLSLLCSLFL
LSVSCFFLLYVSSSDQDLLPVDQKAVLVTGADSGFGHALAKHLDKLGFTVFAGVLDKEGP
GAEELRKNCSERLSVLQMDVTKPEQIKDVHSEVAEKIQDKGLWAVVNNAGVLHFPIDGEL
IPMTVYRKCMAVNFFGAVEVTKVFLPLLRKSKGRLVNVSSMGAMIPFQMVAAYASTKAAI
SMFSAVIRQELAKWGVKVVTIHPGGFQTNIVGSQDSWDKMEKEILDHFSKEIQENYGQEY
VHTQKLALPVMREMSNPDITPVLRDIQHAICAKNPSSFYCSGRMTYLWICFAAYSPISLL
DYILKNYFTPKLMPRALRTAS
>P37058|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGI
GKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKL
AGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLI
LNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLN
TNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYV
AYLKLNTKVR
>P70385|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus musculus|Swiss-Prot
MEKLFIAAGLFVGLVCLVKCMRFSQHLFLRFCKALPSSFLRSMGQWAVITGAGDGIGKAY
SFELARHGLNVVLISRTLEKLQTIAEEIERTTGSCVKIVQADFTREDIYDHIKEHLEGLE
IGILVNNVGMLPSFFPSHFLSTSGESQNLIHCNITSVVKMTQLVLKHMESRRKGLILNIS
SGAALRPWPLYSLYSASKAFVYTFSKALSVEYRDKGIIIQVLTPYSISTPMTKYLNNKMT
KTADEFVKESLKYVTIGAESCGCLAHEIIAIILNRIPSRIFYSSTAQRFLLTRYSDYLKR
NISNR
>O54939|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rattus norvegicus|Swiss-Prot
MEQFLLSVGLLVCLVCLVKCVRFSRYLFLSFCKALPGSFLRSMGQWAVITGAGDGIGKAY
SFELARHGLNVVLISRTLEKLQVISEEIERTTGSRVKVVQADFTREDIYDHIEEQLKGLE
IGVLVNNVGMLPNLLPSHFLSTSGESQSVIHCNITSVVKMTQLVLKHMESRRRGLILNIS
SGVGVRPWPLYSLYSASKAFVCTFSKALNVEYRDKGIIIQVLTPYSVSTPMTKYLNTSRV
TKTADEFVKESLKYVTIGAETCGCLAHEILAIILNLIPSRIFYSSTTQRFLLKQFSDYLK
SNISNR
>Q6P3L6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Danio rerio|Swiss-Prot
MESFNVVETLQPAERALFWVGALITASLALYVVYKTITGFRIWVLGNGDLLSPKLGKWAV
VTGATDGIGKSYAEELARRGFSMMLISRSQEKLDDVAKSLESTYKVETKTIAVDFSQIDV
YPKIEKGLAGLEIGILVNNVGISYSYPEFFLHIPDLENFITTMINVNITSVCQMTRLVLP
RMEARAKGVILNISSASGMFPVPLLTIYSSTKAFVDFFSRGLQTEYKCKGIIIQSVLPFF
VATKMTKIRKPTLDKPTPERYVAAELNTVGLQDQTNGYFPHAVMGWVTTILAPIDLVLNL
GLRMNKAQRGGYLRRRKLR
>Q5XG41|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xenopus laevis|Swiss-Prot
MAPESLVEVPGCNCFWYLGVLAAAWWGLRAACCLLNGARAWVLGSGAQVGPRIGKWAVVT
GATDGIGKAYAEELARRGMSIVLISRSPEKLDEAAKHIKETFKVETKIIAADFGKPTEIY
ERIEAGLRDLEIGVLVNNVGVSYEYPEYFLEIPDLENTLDKMININIMSVCQMTRLVLPG
MLGRGKGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLHAEYRNKGINVQSVLPFYV
ATKLAKIRKPTWDKPSPETYVRSAVNTVGLQTQTNGYLPHAIMGWISTSLVPVSVAISMG
MKMNKGLRSRFLKRKKQK
>Q6QA33|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Danio rerio|Swiss-Prot
MEPFADALFWVGAVTVLWLSVSSLWSLINGIRVWILGNGNLMRASSLGKWAVVTGATDGI
GKAYAEELARRGFAIVLISRTQEKLDEVSKAIESKYKVETKTISADFGSVDIYPKIESGL
AGLEIGVLVNNVGVSYSYPEFFLNIPDVDSFINNMININIMSVCQMTRLVLPRMVDRSKG
VILNVASASGMYPVPLLTLYSSTKAFVDFFSRGLDAEYKSKGIIIQSVLPFYVTTKLSKI
RKPTLDIPTPERYVKAQLSTIGLQTQSNGYLPHAIMGWVTASLLPAKLLNKYVMGMGLSQ
RARYLKKQKQG
>Q8AVY8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xenopus laevis|Swiss-Prot
MAPESLAEVPGCNCFWYLGVVAATWWGLRAAWCLLNGARVWVLGSGAQVGPTIGKWAVVT
GATDGIGKAYAEELARRGMNIVLISRSPEKLEEAAIHIKQKFKVETKIIAADFGKPTEIY
ERIEAGLRDLEIGVLVNNVGISYEYPEYFLEIPDLENTLDKMININIMSVCQMTRLVLPG
MLGRGKGVVLNISSASGMYPVPLLTVYSATKAFVDFFSRGLHAEYRSKGVTVQSVLPFFV
ATKLAKIRKPTWDKPSPETYVRSALNTVGLQTQTNGYLPHAITGWISTSLVPVSAAISMG
MKMNKGLRARFLKKAKQN
>Q9R092|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus musculus|Swiss-Prot
MWFYLVTLVGLYHLLRWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAAC
LTEKGAEELRNKTSDRLETVILDVTKTESIVAATQWVKERVGDRGLWGLVNNAGVLQPFA
YIEWYRPEDYMPIFQVNLIGLTQVTISMLFLVKKARGRIVNVSSALGRVALFGGFYSCSK
YGVEAFSDVLRHEVQDFGVKVSIIEPGSFKTEMTDAELTIERTKKVWEAAPEHIKESYGQ
QFFDDFCSTTKRELMKCSRNLSLVTDCMEHALTSTHPRTRYSAGWDAKFFFIPLSYLPAS
LVDYLLAISRGKPAQAA
>O54753|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rattus norvegicus|Swiss-Prot
MWFYLVTLVGLYYLLRWYRERQVVSHLHDKYVFITGCDSGFGNLLARQLDRRGMRVLAAC
LTEKGAEELKSKTSDRLETVILDVTNTDSISAATQWVKEHVGDKGLWGLVNNAGVFQAFA
YIEWCRPEDCMSIFQVNLIGLAQVTLSMLFLVKKARGRIVNVSSVLGRVALFGGFYSCSK
YGVEAFSDVLRREIRDFGVKVSIIEPGSFKTRMTDAELIIEKTKKTWEATPEHIRESYGQ
QFFDDFCNTTRRELKKCSTNLSLVTDCMEHALTSKYPRTRYSAGWDARLFFIPLSYLPTS
LVDCLLAISRRKPAQAV
>Q93W57|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sesamum indicum|Swiss-Prot
MDLIHTFLNLIAPPFTFFFLLFFLPPFQIFKFFLSILGTLFSEDVAGKVVVITGASSGIG
ESLAYEYAKRGACLVLAARRERSLQEVAERARDLGSPDVVVVRADVSKAEDCRKVVDQTM
NRFGRLDHLVNNAGIMSVSMLEEVEDITGYRETMDINFWGYVYMTRFAAPYLRNSRGRIV
VLSSSSSWMPTPRMSFYNASKAAISQFFETLRVEFGPDIGITLVTPGFIESELTQGKFYN
AGERVIDQDMRDVQVSTTPILRVESAARSIVRSAIRGERYVTEPAWFRVTYWWKLFCPEV
MEWVFRLMYLASPGEPEKETFGKKVLDYTGVKSLLYPETVQVPEPKND
>Q8LKV5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sesamum indicum|Swiss-Prot
MDLINSLLNFVVPPASLLMLAFTWPTLFFITTCEWLYNTYLNSENMENKVVLITGASSGI
GEQIAYQYAKRGANLVLVARREHRLRGISENARRLGAPNVLIMAADVVKEEECRRFINET
INYYGRVDHLVNTVSLGHTFYFEEASDSSVFPILMDINFWGNVYPTYVALPYLRESNGRI
IVNASVENWLPLPRMSLYSAAKSALINFYETLRFEVKNEVGITVATHGWIGTEMTRGKFM
VEEGAEMQWKEEREVHVTGGPVEEFAKQIVSGACRGDPYVKYPSWYDIFFLYRVFAPKVL
DWTFRFLLTNGGARRTSFIGTGRPLLETSSPRRSAVMEGSSPRRLPPGPLTFSPAFQQQK
SE
>A0A140FAN3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pinus massoniana|Swiss-Prot
MDVMNFLLNLVVPPAGLLMLAFAWPSLAFFRACEWALRIIYGEDMEGKVVIITGASSGIG
EQIAYQYAKRRANLVLVARREHRLRSIREKARTLGAKNVLVIAADVVKEEDCKRFIDETI
NQYGHLDHLVNNAGLGHSFLFEEASDTSGFAHMMDINFWGSVYPTFFALPHLRRRNGRII
VNASVEGWLPMPRMSLYNAAKAAVVSFYETLRIEIGGAIDITIATPGWIESDMTRGRFMT
EEGEVLFKEEPREMYVGPYPVAYTEECARTIVSGACKGQRYVRFPMWYNVFFLYRVFVPD
LLDWTYRLLFLNHFITTASKDHTLHDFKGARKKLLITPTSLQLLHHQQHQSPKSSE
>Q8NBQ5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLK
SKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNN
AGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVP
FLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPE
EVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKQKISVKFDAVIGYKMKAQ
>Q4JK73|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Crab-eating macaque|Swiss-Prot
MKILLDLLLLLPLLIVCCLESFVKLFIPKRRKSVAGEIVLITGAGHGIGRLTAYEFAKLK
SKLVLWDINKHGLEETAAKCKGLGAKVYTFVVDCSNREDIYSSAKKVKAEIGDVSILVNN
AGVVYTSDLFATQDAQIEKTFEVNILAHFWTTKAFLPAMMKNNHGHVVTVASAAGHISVP
FLLAYCSSKFSAVGFHKALTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPALEPE
EVVNRLMNGILTEQKMIFSPSSIAFLTILERILPERFLAVLKRKINIKFDAVIGYKMKAQ
>Q4JK73|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Macaca fascicularis|Swiss-Prot
MKILLDLLLLLPLLIVCCLESFVKLFIPKRRKSVAGEIVLITGAGHGIGRLTAYEFAKLK
SKLVLWDINKHGLEETAAKCKGLGAKVYTFVVDCSNREDIYSSAKKVKAEIGDVSILVNN
AGVVYTSDLFATQDAQIEKTFEVNILAHFWTTKAFLPAMMKNNHGHVVTVASAAGHISVP
FLLAYCSSKFSAVGFHKALTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPALEPE
EVVNRLMNGILTEQKMIFSPSSIAFLTILERILPERFLAVLKRKINIKFDAVIGYKMKAQ
>Q9EQ06|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus musculus|Swiss-Prot
MKYLLDLILLLPLLIVFSIESLVKLFIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLN
TKLVLWDINKNGIEETAAKCRKLGAQAHPFVVDCSQREEIYSAAKKVKEEVGDVSILVNN
AGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPVMMKNNHGHIVTVASAAGHTVVP
FLLAYCSSKFAAVGFHRALTDELAALGRTGVRTSCLCPNFINTGFIKNPSTNLGPTLEPE
EVVEHLMHGILTEKQMIFVPSSIALLTVLERIVPERFLQVLKHRINVKFDAVVGYKDK
>Q5NVG2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pongo abelii|Swiss-Prot
MKFLLDVLLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLK
SKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSAAKKVKAEIGDVSILVNN
AGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMMKNNHGHIVTVASAAGHVSVP
FLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPE
EVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYRMKAQ
>Q6AYS8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rattus norvegicus|Swiss-Prot
MKYLLDLILLLPLLIVFCIESFIKRLIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLN
TKLVLWDINKNGIEETAAKCRKLGAQVHPFVVDCSQREEIYSAVRKVKEEVGDVSILVNN
AGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMMKNNHGHVVTVASAAGHTVVP
FLLAYCSSKFAAVGFHRALTDELAALGCTGVRTSCLCPNFINTGFIKNPSTNLGPTLEPE
EVVEHLMHGILTNQKMIFVPGSIALLTVLERVFPERFLDVLKRRINVKFDAVVGYKDK
>O57314|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Anas platyrhynchos|Swiss-Prot
MLPAAGLLWWVGALGALYAAVRGALGLLGALRVWGIGAGRAALGPGLGAWAVVTGATDGI
GKAYAKELAKRGMKVALISRSKEKLDQVAGEITEQYGVETKVIVADFGEREDIYDRIRAG
LEGLEIGVLVNNVGISYSYPEYFIDVPDLDKTIDKMININIMSVCKMTRLVLPGMLERSK
GVILNISSAAGMYPTPLLTLYSASKAFVDYFSRGLHAEYKSKGIIVQSVMPYYVATKMSK
ISKPSFDKPTPETYVRAAIGTVGLQSQTNGCLPHAFMGWVFSILPTSTVMNLLMKTNKQI
RARFLKKKMKEK
>Q5E9H7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bos taurus|Swiss-Prot
METALPAAGFLYWVGASTVAYLALRISCWFFTALRVWGLGHEAGVGPWLGEWAVVTGGTD
GIGKSYAEELAKRGMKIVLISRSQDKLDQVSSEISEKFKVETKTIAVDFTSEDIYDKIKA
SLAGLNIGVLVNNVGMSYEYPEYFLDVPDLDNTIKKLITVNALSVCKMTRLVLPGMVERS
KGAILNISSASGMYPVPLLTIYSATKAFVDFFSQCLHEEYKSKGVIVQSVLPYYVATKLA
KIKRPTWDKPSPETFVKSAMKTIGVQSRTNGYPIHSLVASVSASLPSWLYFKIAMYSGNS
IRVRYLKKMKMN
>Q53GQ0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTD
GIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKT
GLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERS
KGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLA
KIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKS
TRAHYLKKTKKN
>B7Q1K9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MIAGKVNNCAIVNMASMVAKEICPNMSVYSAAKAGVVALTRVAATELAVHGIRVNVVLPE
VVDTPMIAHEFTAEEIAGIVANQPLGRLCRPEEVAETVKFLCGPGSSCTSGVAVDVTYCF
YKNSGRK
>C1L7P3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Schistosoma japonicum|TrEMBL
MRTSTNDMDASSTPHFIKHNFFIFTITLIITWFIFKLLQLLKICLVYTVAKWCFSKRKSL
RKAGEWAIVTGASSGIGEAYAEELAKEGLNILLISNDESQLRLVSERISTDYHVETRIVV
ADFTQNNVYDVIKPAIQQLSTIACLVNNVGMGLPIGPFVGGTQSPSEQSIHDIIHCNVLS
TAMMTHIVLPKMLSQKGSNPGIINIGSFTGLKVLPYASMYAATKAFIIQLSRCISAEKYS
RDVIVQTICPLVVSTKLSFCKPTSFFVPTAQVFAKSALDMFGVQQQTTGYMRHEFKGFLY
TLMPTSLWVKFLQICFVPSMKESTKSE
>A0A2P9H3L6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderiales bacterium|TrEMBL
MAAKATDPGSVLITGASSGIGRELAKIFAAEGYHPVLLARSRDKLQQLAQELKTSQGTKV
TVMPADLSDPEAPRAVFERLRERGIDVDILVNDAGLMFEGDFATIALDEHLRLLHVNVVA
LTALTRLFLEPMLRRSRGRILNVASVGAFLPIPSLATYAASKAYVLSLSEALSEELKGTG
VTVTALCPGFTNTAMVRGSPRGTRLPPLMVMDAKAVAKQGYSACIAGKALHVAGLSNDLA
TWGIQYLPRSLVRTVGGLVARQWT
>G3YFE0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a / NRRL 328 / USDA 3528.7)|TrEMBL
MSTKNIVVIGCGGMGLAAASQGPIEAVIHTAGLSPSAGSAQKILEVDLLGTANAIDAFLE
YARSHGIRLASGVRASSCDSARDQLLEHPALKIDSADPHGPPRAHGLSKRGNILRVQASA
KAWGRVGGRVNTVRPGVISTRTVRKEINGPAGKFIAMSPVGRVGTPQDVVTAVAFLASPE
SSFITGNDILVDGGVVSSLMWDN
>A0A671XYM8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sparus aurata|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLSQVAAFCLVYATMRNMAKKERLLECVKGLHKDTLDIL
QMDVTDQQSILDARDRVVEKRVDILVCNAGMGLMGPLEIQSLDSMRRIMEVNLLGTIQTI
QAFLPDMKAQDKGRILVTGSTGGLHGLPFNEVYCASKFAIEGACESLAVLLQHFNIHVSL
IECGPVNTDFLVNLQKAELGDASLQKVDAHTLSLYERYLQHCGSVFQNAAQDTEDIVKVF
LDAIQSPCPAFRYFTSGVVPPLIKLKITEPDGSRYISAMSKIIFSAEEQ
>A0A812CGP1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sepia pharaonis|TrEMBL
MTSEEIFQKTLNVNLLGTFRLTKAFLPFIRRAKGRIINMSSFAARVPMNGISAYSVSKSA
ILAFSDILRLEMKKWDVHVSIIEPVGFRTNAFNEQVLEARLQEIWDSLDEECQIVYGRQY
LEDLYSSYKELIPRVPSDLSPVVSAVCNSLLSKNPRERYPCGQGADILATLFAILPIRLA
DKVSKFMSVIPKNSRPLALEPSSHLVP
>A0A378JW32|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella moravica|TrEMBL
MKAALITGATHGIGLALTRNLLSKGWTVFGVGRDQDSLDRTSSEFATFRPICADLTNNDD
LKKVADVVNNTKIPLNILVQNAGMKTPPRDLEKHTCEAIDEVIGLNLSAPMKLTALLIPC
MPSGSRILYVTSRAATLKLMQSSTYCATKAALDEVAAIVRQELREKNIAVGSVIPGEVNT
SIQKTLRETTGFHLHRMFQQAYESGQLIRPEICADFLKWLLCDLSFEEFNNGEIHTIYDD
AHHKYWLANPEDLPAFPFEDKPQNTLLMSKL
>A0A378JXD0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella moravica|TrEMBL
MKVALITGAASGIGLALSQLYLQRGIKVVMVDKDSSKLIKEANELNELYPGLALNKTCDI
TKPDDIEQLLAYVDTHCGRIDWLYNNAGIIGSLAPVWELQPEQLNQVMDVNLHGMIHVIR
IFMPYLFKQPFHSHIINMGSLYGLCSGSQIAAYSMSKHAVLALSESLFYDLKRLEKPVDV
SVVFPSFTDTSLLSTNPAESNSVFHESLNSLLAHSRPASDVALHIIQEVEQKRFYILPDK
EVKGYCEERTNAIVRQENPYINNIEKLMNALIKRKHALRSVDN
>A0A8C7P041|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Oncorhynchus mykiss|TrEMBL
MEQTVVLITGCSSGIGLSLAVRLASDPAKMYKVYATMRNLAKKERLLDCVKGLHKDTLDI
LQMDITDQQSILDARDRVREKRVNILVCNADVGLMGPLEAQSLATMRRILEVNLLGTIST
IQAFLPGMKAQGHGRVLVTGSIGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLDNLQRAEPGDSSLQQVDAHTRSLYDTYLQHCGMVFQNAAQDTEDIVKV
FLDAIQSSNPAFRYYTNNALIPLSSPKISALDGSQYIRNMSKIIFSTNGKGEQK
>A0A3Q1B7R6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Amphiprion ocellaris|TrEMBL
MSPSYCLALLVAFLSLCSSCSPLKVGKPGSMDKKVVLITGCSSGIGLSLAVRLASDPDKR
FKVYATMRNLAKKERLLECVKGLHKDTLDILQMDVTDRQSILYARDRVVEKRVDILVCNA
GVGLMGPLEVQSLDSMRRILEVNLLGTIQTIQAFLSDMKAQGQGRILVTGSTGGLHGLPF
NEMYCASKFAIEGACESLAVLLQHFNIHVSLIECGPVNTDFLVNLQKVELEDATLQQVDA
QTISFYEKYLQHCSSVFQNAAQDTEDIVKVFLDAIQSPSPAFRYFTTSVVPPLTKLKMTE
PDGSQYISAMSKIIFSAEDQ
>A0A8C9V9Q8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Scleropages formosus|TrEMBL
MERLVVLITGCSSGIGLSLAVRLAADPRGAYKVYATMRNVAKKERLMECVKGSRKDTMDV
LQMDVTDQQSILEARDMIKEKRVDILVCNAGVGLIGPLEVQSLEVMRQILEVNVLGTIRT
IQAFLPGMKARRSGRVLVTGSVGGLQGLPFNEVYCASKFAVEGVCESLAILLQHFNIHVS
LIECGPVNTNFLANLRRPEPDEETLTRVDPRTRALYDTYLQHCDEMFQDAAQEAEDIAEV
FLEAIRSQSPALRYYTNSALLPLTTLKLAARDGSQYVKSMSQFVFSSHKAQEP
>A0A6J8EJ51|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mytilus coruscus|TrEMBL
MAVCLCTRESVKMMRANGVDDGHIININSLSGHRCGKAHFYSATKHTVTALTEGIRWELR
EINSHIKVTSISPGLVKTNFAYTAVGEAAAEECYSTRQSLDPQDISNAIETVLSYPSHVQ
VSEMMIRPTEQAVTCGVNNAHLNCFLIVSTPPMTITDLKAFRSAINAKRMHKVDNGCLVK
GKCHRSQRKNESPHDIEIILLDGPILQCSKCSCAIGKLGTCGHVTGLLYSLAHMKTCNYK
SIPSDVLKTSLPQSWHMPRGEKVKGNTADDVIVVGYNTKSPYRQPRGLRSTFYNPIKVPL
PPVADLCSAISDIDNSCLLLSVTSHHNTSNMIETRFGKYPKGSPISYQQKLSSHFILNVL
DADFPFAS
>A0A3B3Q527|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Paramormyrops kingsleyae|TrEMBL
MDQTVVLITGCSSGIGLSLAVRLASDPSKIYKVYATMRDLAKKKRLMDCVKDSHKDTMDV
LQMDITHHQSILDVRDGIKEKRVDILVCNAGVGLVGPLESQSMEMMRQILEVNVLGTIRT
IQTFLPGMKARGSGRVLVTGSIGGLQGLPFNEIYCASKFAVEGVCESLAILLQHFNIHVS
LIECGPVNTDFLANLRRTEPGDASLSQADARTRALYATYLQHCDTMFQDAAQEAGDIVQV
FLEAIEAQSPALRYYTNSALLPLTTLKLAARDGSQYVKAMNKFIFSIDKAGDC
>A0A8C4ZNH8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Gadus morhua|TrEMBL
MEKKVVLITGCSSGIGLSLAVRLASDPDKTYKVYATMRNLAKKERLLGCVKDLHKDTLDI
LQMDVTNHQSILEARDRVVEKRVDILVCNAGVGLIGPLEAQGLDTMRQILEVNLLGTIQT
IQAFLPDMKARCKGHILVTGSIGGLHGLPFNEVYCASKFAIEGACESLAIILQHFNIHMS
LIECGPVNTDFLDNQEKAELGDASLGQVDASTLSLYGQYLHHCTTMFQNAAQDTEDIVKV
FLGAIQASRPSFRYYTSGAMPPLVRLKTSFPEGCRFIRAISQLIFPTESSHLDGSRRSPL
GPL
>H0YWT6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Taeniopygia guttata|TrEMBL
MERTTVLITGCSSGIGLGLAARLAADPARRFKVYATMRDLAKGERLLERLGGCCPDTLEL
LQLDVTDPCSLAAAAQRVQGQRLDVLVCNAGVGLMGPLETCSDQAMKTLFDVNLFGAVRT
IQAFLPAMKSRRAGRIIVSSSIGGLQGLPFNAVYCASKFAVEGLCESLAIVLRPFNIHLT
LVECGPVHTSFLANLQRPDPEGSEMRGLDAETQGLYRRYLGHCQSIFRDTAQEVEEVLPV
FLEAIGSPCPPLRCASTQLLAPLWRLRLSSPDGSEYVRAMHDFVFGSSETGGDQP
>G9AH70|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhizobium fredii (strain HH103)|TrEMBL
MTQHSKGTALITGASSGIGAIYADRLARRGYDLILVARNSARLNELAKRLTDETGRAVEV
VAADLGNKADLGRVEQILQADASITLLVNNAGVGATAPLLASDVDKMEEMIALNVNALTR
LTYAAVPGFVARGTGAIINIASIVGIAPELLNGVYGGSKAFVLAFTLSLQKELTDKNIRI
QAVLPGATATDFWGIAGTPLEHVPSEIVMPAEDMVDAALAGFDLGERITIPSLPDAADWE
TYEAARQKLMPHLSRNIPAARYRTAIR
>A0A8C9Y939|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sander lucioperca|TrEMBL
MHMANCSLLKQTVGEPDSMDKKVVLITGCSSGIGLSLAVRLASDPNKTFKVYATMRNLAK
KERLLECVKSLHKDTLDILQMDVTSRQSILDARDRVVEKRVDILVSNAGVGLMGPLEVLS
LDSMRQILEVNLLGTIQTIQAFLPEMKAQGQGRILVTGSTGGLQGLPFNEVYCASKFAIE
GACESLAVLLQHFNIHLSLIECGPVNTDFLVNLQKAELGDTCLQQVDALTLSLYEKYLQH
CGSVFQNAAQDTEDIVKVFLDAIQSPSPAFRYFTSGVVPPLTRLKISEPDGKRYISALSK
TMFSAEEQ
>A0A674IIK0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Terrapene carolina triunguis|TrEMBL
MEKTVVLITGCSSGIGLGLAVRLASDASRRFKGTARGLGGIAISKLGARSLLVYATMRNL
AKKERLLECVRGCHASTLEILQLDVTDPLSLAAAAQQVQEQRVDVLVCNAGVGLMGPLET
CSFQAMKTIFDVNVFGTIGTIQAFLPGMKRRKAGKIIISSSVGALQGIPFNAVYCASKFA
VEGLCESLAVILQQFNVHVTLIECGPVNTSFLANLQRTDAEGSALQGLDPQTRALYSQYL
QHCQSLFRDVAQDTEEVLQVFLEAICAPCPPLRSFTTQFFMPLTRLKLTSPDGSEYVRAM
HKFVFSAGKAQGDQAEGQVRREAAPVLP
>F4L8E0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O)|TrEMBL
MTQKTWLITGISSGLGQALAQTVIERGDRVIGTFRQQSQIDAFNDLYQNRAIGIKLDLTN
STEIQDAFEWIKSNIGKLDVLVNNAGLGFAGAIEETSDAETRAVFEANFFGVLNLTKAFL
PLFRQQKSGHIIQISSHGGFKAFAGFGIYNASKFALEGFSEALAQEIAPLGIKLTIVEPG
PFRTNFAGSSLKFAEQTIDDYLVTAGAFRERLKSVNGMQEGDPHKAATAIYNLTSLDTPP
LRLPLGKVAVHSLTSKLASVQTDLDSYRDVAEGSVY
>A0A0W0TNB0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella feeleii|TrEMBL
MEKTALVTGATHGIGLALSKNLLSNGWLVFGTGRDLASLETTQALFPDFIPIQADFTQND
DIENVATTIKKTGLPLHLSVQNAGMKSPPRPLEQYTCGSIDEVLMVNLLAPMKLTALLTS
QMPSESRILYLTSRAATLKLKDGSTYCASKAGLDEVAAIVRQELEERNIGVSSVIPGEVD
THIQKILRETTSFHLHQKFEEIYQKGQLISPAVCAAFLKWLLCDLPFAEFKQSKMPVSIY
DKWHHQFWLTDANQLPACPF
>Q6NNV7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MERWHNCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREELPQDRRSRLRI
MQCDVSDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVV
YCTQRAFESMRQRQSKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQ
EMRDFKTKVKVTSISPGLVDTELVPLDYKGLPMLQAEDVANAIMYVLSTPPHVQVHELTI
KPLGEPF
>H0VX11|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cavia porcellus|TrEMBL
MDPAARTVVLITGCSSGIGLHLAVRLASDPSRSFKVYATMRDLAAQGTLWEAARARRCPP
ESLETLELDVRDSDSVAAARARVTEGRVDVLVCNAGRGLLGPLEGHGPGAVGSILDVNVV
GTVRTVQAFLPDMKRRGSGRVLVTGSMGGLMGIPFNAVYCASKFALEGLCESLAVLLLPF
GVHVSLIECGPVHTAFYEKLEGGLGGALDQADARTRHLFSLYQRHCERVAREAQDPEEVA
EVFMAALHAPQPALRYFCTERFLPLARLRLDDPSGRSYVAAMHHAVFVADPGAMQSGDSE
PDAAPETAVHASDRCPL
>A0A3P8WHR2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cynoglossus semilaevis|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPQKSFKVYATMRNLDKKERLLESVKGLHRDTMDI
LQMDVTDQRSIHDARDRVVEKRVDILVCNAGVGLMGPLELQSLNSMRQILEVNLLGTIQT
IQAFLPEMKAQGRGHILVTGSTGGLHGLPFNEVYCASKFAIEGACESLAVLLQHFNIHVS
LIECGPVNTNFLVNLEKAELGDAPLRLVDPLTVNLYEKYLQHCSFVFQNAAQDTEDIVKV
FLEAIQSPSPAFRYFTSGALSPLTQLKTAQPDGTQCIRAMSDIIFSSKEK
>B9RMQ7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ricinus communis|TrEMBL
MLACINHLTTQPLWLLIVSFLGFLSLFNYSFTLLNWVYKTVLRQPKNLKENYGSWALITG
ATDGIGKAFAFQLAKQGLNLILVSRNLNKLKTVSSEIQEEFPSTKIKIMNLDFSSEDSSG
LVHVIEEAIKGVDVGVLINNVGITYPQARFFDEVDESTWMSVVKVNVKGTTRVTEAVLSG
MIERRRGAIVNIGSGASIVVPSHPLYTIYAATKAYIDQLSRCLYVEYRSCGIDVQCQVPL
YVATNMTSRVALIEKSSLFIPSPQAYAEAAIRCIGYEARCTPYWAHSLQWFFVRLLPEAV
LDSWRLSIGIHRRGNIIISSTSAGVHGNDRE
>B9RMR1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ricinus communis|TrEMBL
MELQDFILLTVSGIGFISLIKQTFTFLNWVWAMFLRPAKNLKQQYGSWAVITGSTDGIGK
ALAFELASKGLNLVLVGRSPSKLEDTSKEIQERNGKKSQVLIKTIVLDLARTSGEEISRK
IEDCIEGLDVGVLINNAGLAYPYARFFHEVDLELTESLIKVNTEGATWVTKAVIPFMLKK
KKGAILNIGSGSSFIIPSYPLNAIYASTKAYLAMFSSCISLEYKDQGIDIQCQIPLFVAT
KMTRIKKSNLIIASPKMYAKASIRWIGYEKLCTPFWSHSVQWLILKALPEELLDRSLFRH
YIGLRKKGMEKELLKKSQLQASQG
>B9TF06|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ricinus communis|TrEMBL
MRDPVNFESRRMNYQAPAQHLKDRVILVTGAGQGIGREAAKAFAAQDATVILLGRKQSKL
EEVYDEIEAAGHPQPAIFPIDLAKAGEAEFKALAEAIYAQLGRLDGILHNAARFDNLSPL
EIQNAEQFNGMLRVNLIAPFLLTKACFPLLKRSPDASVVFTSTTAAHYPAAFWGAHAISK
SATETMAKIWSEEIGLLPNLRMNTVIPGAIQTPQRKKSHPGEIAENRPEISTILPLYLYL
MGQDSAGVNGQLFEALKTSAQ
>A0A8D2ASZ9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sciurus vulgaris|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSRSFKVYATMRDLRAQGSLWKAARARGCPSDSL
ETLELDVRDSDSVAAAQARVTEGRVDVLVCNAGRGLLGPLEAHGLGAVGSVLDVNVVGTV
RTLQAFLPDMKRRRSGRVLVTGSVGGLMGLPFNAVYCASKFALEGLCESLAVLLLPFGVH
VSLIECGPVHTAFYEKLEGGPGGALDHTDSQTRHLFSLYQRHYEQIIREAQDPEEVTEVF
LKALLAPKPALRYYSTERFLPLARLRLDDPSGCSYVAAMHHAVFADQPAEAGEDGDPELG
ASPAALK
>G8NTQ4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)|TrEMBL
MAKTILITGASSGIGRATALYFAEKGWNVAATLRDPLKADPILQHPPISLFALDVTNADS
IAQAISDTLSRYQKIDVLLNNAGYGLFGPVEALGSQQIQQQFATNLFGLISVTQQVLPIM
RAAGEGLILNVSSIVGRMALPYASSYVATKFAVEGVSESMRYELEPFHIRVKLIEPGSIS
TEFGKGSMQMAVSDPYRESMNKFLNVFTKSSSRAARPEEVAKIIYRAANDSSNRLRYLAK
PGPFFWMNRILPDAIWRPLLVKVMVK
>A0A8B6BZT6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mytilus galloprovincialis|TrEMBL
MASNVQSFLGNYSDLFAVAGVVSVSYIALKLALSIFNGIKVFLLAKPLGLTKNLKKCGQW
AVVTGATDGIGKGYTHQLAKKGMDIILISRTKSKLEDCAKEIEQKFKVKTKIIVADFSAG
LQIYDAIRSQLAGLDIGVLVNNVGMSYDFPMYFLEIPDREKKIMDLLHVNITSVTMMTSV
VLPEMVSRSRGVVINVASASGVNPCPLLTVYSASKAFVHYFSLCLEREYRDRGITVQSVL
PYFVATKMSKVKKGSFWIPYPDQYAASALDTVGFEKATNGWWSHSITVSIFTGDSLFSLL
TSYLDIVMF
>A0A5B7BLL0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Davidia involucrata|TrEMBL
MELCFMDQLKSQPLWLLLLLGLGSVSVLKCSLALLKWVYVNFLRPAKNLKKYGSWALVTG
PTDGIGKGFAFQFARKGLNLVLVGRNPDKLKEVSESIRAKYGKTQIKTVVVDFSGDLSQG
VERIREAIEGLDVGVLINNVGVSYPYARFFHEVDEKLLADLIKINVEGTTTVTHAVLPGM
LKRKKGAIVNIGSGAAIVIPSDPLYAVYAATKAYIDQFSRSLYVEYKKSGIDVQCQVCSK
GNNDLNYLSPRRIT
>A0A3R8BB77|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii CAST|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALVRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKAMAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>A0A8C6QXD9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Nannospalax galili|TrEMBL
MDRTVVLITGCSSGIGLHLAVRLASDRSQSFKVYATLRDLKSQGPLLEAAQARGCPPGSL
ETLALDVRDSESVAAARARVTEGRVDVLVCNAGRGLFGPLEAHKLDAVGSVLDVNVVGTV
RMLQAFLPDMKRRRSGRVLVTASVGGLMGLPFHAVYCASKFALEGLCESLAILLLPFGVH
VSLIECGAVHTAFFAKLEGGLGGDLERADAPTRRLFAHYLRGYKRILSEAQDPEEVTELF
LTALRAPQPALRYFSTEHFLPLARLRLEDASGCSYVAAMHREAFAGLQVQEETEARTCVG
PRLLRALCLPRWVASELCWPTSDKTSQDKLCCRL
>F6DFC7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Thermus thermophilus (strain SG0.5JP17-16)|TrEMBL
MRLAGKVVVVTGAGSGLGQALALELLRRGARVAAVDLRSEGLQETMTKAGSLGEGLSLHP
LDITDKEKVAALPEEVERVHGQVDGLINNAGIIQPFKRLLDLDEAAMERVMRVNFWGTLH
MTRAFLPRLLKRPEAHLVNVSSMGAFVPVPGQALYGASKAAVMLLTEALWAELQGTPVRV
TLVLPGAMRTGIAEHSGVEAPRAEGAKVPVLEPEVAAKRLLDAVERDAFRVLLGRDAQTM
DLLYRLSPALAARIVQRRMAHLLT
>A0A0D9S1S4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Chlorocebus sabaeus|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARARGCPLGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEAVGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVSGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVAAMHRHVFGDDPAEAEAGAGPGA
GAGPSEVGDPELGDPPAAPQ
>A0A422PII9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Trypanosoma conorhini|TrEMBL
MTFLCSSLAYVGALAVAVALYRLVKFLYVNLLAATDLRRRYARAGDWAVVTGATEGIGYA
MAMDLARRGFNVCVIARTRSRLEEVVAAAEQKGVRAKAVVFDFAAADASEYKRLFAELDA
LEVAILVNNVGVNYPYANFFDEAAAEDDLRMLKVNCEATLRMTRYIVPRLKAKRSGGVVM
LASISAVIPTPMLAAYAGSKAFSISFAQGLAYELRPFGVDVLVVTPSLVVSKMTQGVSTR
KPRESFMMVNAAAMARQTLNKLGVVTRTCGHLNHALVELVATALPEAWLANQVLAQNKAL
KKRAERQRPQ
>A0A0A1TXH8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Entamoeba invadens IP1|TrEMBL
MGKNTGAYLLGVLGAIVSVITVIPALMFLWRMVIRPLLFKPTTKVYKGTETYAIVTGAAG
GVGKGFTEKLAKEGFNLIVIDRDEKALNEVAKVIEEKYKVKVVVKVLDLIAMERGDETAW
TKFIEEITPLDIGVLVNNVGMCQYLPGNYDTVALKDVRNMITLNISSMLTLTHYVIPLML
KRQQKGLIIGMSSSTSFMPFPMFQIYSSTKAFVRQFHDSINIEYAGKIDAISYAPWYVAT
EMTKIREKAIYVLSPQEFVEESFKHIGFETHIDPYWFHYLMDFGAWAIPTAIYGKLVAKE
QVFVRGRLLKKLEEKQASEKKKE
>A0A2K6KR96|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhinopithecus bieti|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARAWGCPLGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEAVGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREAAQTPEEVVEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVAAMHRHVFGDDPAEAEAGAGTGG
GAGPSGVGDPELGDPPAAPH
>A0A3B4WZ99|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Seriola lalandi dorsalis|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPEKTFKVYATMRNLAKKERLLECVKGLHKDTLDI
LQMDVTDRQSILDARDRVVEKRLDILVCNAGVGLMGPLELQSSDTMRQILEVNILGTIQT
IQAFLPEMKAQSQGRILVTGSTEGLHGLPFNEVYCASKFAIEGACESLAVLLQNFNIHVS
LIECGPVNTDFLVNMQKAELGNTSLQQVDTKTVSLYEKYLQHCDSVFQNAAQDTEDIVKV
FLDAIQSPSPTFRYFTSGGVPPLTQLKITEPDGSQCVRAMSKIIFSVEEQ
>A0A3P9D8H0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Maylandia zebra|TrEMBL
MPPFYSVAHFAVSSSLCSTGSFNVGELGSMDKKVVLITGCSSGIGLSLAVRLASDPDKTF
KVYATMRNLSKKERLLESVKGLHRDTLDILQMDVTDQQSILDARDRIVEKRINILVCNAG
VGLMGPLEVQSLNSMRHILEVNLLGTIQTIQAFLPQMKAQSQGRILVTGSTGGLHGLPFN
EVYCASKFAIEGACESLAILLKHFNIHVSLIECGPVNTDFLVNLKKTELGDTSLQQVDTQ
TQRLYEKYLQHCRSVFQNAAQDTEDIVKVFLDAIQSPSPAFRYFTSTTGPPVTQLKVTEP
DDSYISAMSKIIFSPEEQ
>E0QS15|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mobiluncus mulieris ATCC 35239|TrEMBL
MIGRPDSQGGLGMFFRPKLAPVRGAVVLITGAGSGIGRLMALEAAKRGAKAVIIWDLNGE
TAEQTAAEILDLATREAATLPRPLRASAYTVDVTSDGQVDAAAKAVLEEYGRVDILINNA
GILAGKPFLETTQAEIERSFQVNTLAHYRTTRHFLPGMIKRDRGSVVTIASAAGLVGVPR
QCDYNGSKFGAVGFAQSLREELRHMGSHVHTLLYCPYYISTGMFEGVQTKFPLVLPIARP
QQIACQVLDAIDRGTQFKVNPPIVRLVQLAQALPVPIMDPIVEFFGVLDTMNEFIGRVAK
TKS
>E0VZ61|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pediculus humanus subsp. corporis|TrEMBL
MTPLEVIGLLSVLYFGCHIALKLATFVYYNCVKCSMNKDVLVKQRGKWAVVTGATDGIGK
AYANSLGELGMNVVLISRNMNKLNECAGEIEAKYNVSTKVIAVDFTQDVSIYETIENSLS
NLEIGVLVNNVGISYSYPEVFLDIPDKAKFFTALINANIVSVTKMCDVVMPKMVERKNGV
VINISSASALLPSPMLTVYAATKRYVEKFSDELRTEYKDKGLVIQTVLPGFVATKMAKLK
KSSLFAPSPSTFVQSALSKVGVHDHTTGYLPHTIFVGAINAIHSVCPAFANYFVMNSLKK
VRAKAIASSKKKAAIQS
>A0A0K2VWM0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mesorhizobium plurifarium|TrEMBL
MFDRKRKTALVTGASSGMGKEIAKRLIRDGYQVYVAARQVDKMEDLAALGARPLRMDISK
DADIEAAVASILAEVDGVDVLVNNAGFGLYGPVEDIGIDEARYQFEVNVFGPARLTQLLL
PSMRRKKAGTIVNITSMGGKIYTLLGAWYHATKHALEGWSDSLRLELAPFGIKVVVVEPG
LIETGFGDVVADGLLKRSGASVYAQVAQMVAKTTKASYGHGRGSDPRVIADVVSAAVSSA
RPRTRYAAGKYAKMMIGVRKWFGDRVFDRLILSQMR
>A0A8C8H3M5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Oncorhynchus tshawytscha|TrEMBL
MEQTVVLITGCSSGIGLSLAVRLASDPAKMYKVYATMRNLAKKERLLDCVKGLHKDTLDI
LQMDITDQQSILDARDRVREKRVNILVCNAGVGLMGPLEAQSLATMRRILEVNLLGTIST
IQAFLPGMKAQGHGRVLVTGSIGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLDNLQRAEPGDSSLQQVDAHTRSLYDTYLQHCGMVFQNAAQDTEDIVKV
FLDAIQSSNPAFRYYTNNALIPLSSPKISALDGSQYIRNMSKIIFSTNGKGEQK
>A0A2T6J3U5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii TgCATBr9|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALVRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKAMAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>A0A5E6MEB2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Methylacidimicrobium cyclopophantes|TrEMBL
MKRTFIGSSAWITGASSGLGAEFARQLAPEAACLVLTARREERLRELAEELRRKRPKLQI
VVAPADLTCAEAVEGVLDLLTRERIEVDTLVNNAGSGDSGLFYRGDWDRLRSMLDLNVGA
FTRLLWWLLPRMIRRGKGCIINVGSIAGLRPVPFYSAYAATKAYVHSLSHGLEWELAGTG
VTLTQVCPASVATEFFERAARSPEDLKKIAGPSFMWTSPEEVVRCSLDAARRGKPQVTPG
FVPGLCAAIFSYVPIPLLRMAYRAVLSGKRKPGGELAEERMWMEKQADGRPL
>A0A6J8CLA1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mytilus coruscus|TrEMBL
MLAGRLALVTGAGSGIGQAICQAFAKEGALVAMADVNKDGVHHVHETLKSISEGNHHPFT
VDVSSSASVATLLTDIRDRYMAVPTIAVNSAGITRDTYMLKMKEEMWDEVINVNLKGTYL
LNKAVGNVGQTNYGASKAGVIGFTKSAAKELAKFNIRVNAILPGFIKTPMTEKVPEHLMQ
ITQMLIPMTKLGEPEDIADACVFLASDKSRYITGATLEVSGGLFM
>A0A6J8EVK7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mytilus coruscus|TrEMBL
MTVLFDSDNSIKYGMVREIQQRVELKPISMDMMINLSWATTSISIYILYATVILHWYKSH
MIQLRLKDINGLLVLAGLSLCLVKYGLELQGSLVLLLGIVVSYLQLSPVILPINNKAILI
TGCDRGIGKALAKYLDKAGFKVYAGCLENEGHGKQNLMNSCSPRLQTIQLDVSNESQIKT
AAAIVQKDLEMSGMKLWGVINNAGIGMKLWGVINNAGICFIGNVEMMVTEDIHKILAVNY
LGPVTVCKHFLPLLRESQGRIVNVASNCGLAPVPLMGPYCASKSALATMSEVWRYEFKMW
KIKVCTIIPSGYKTERWWKGASKSVKENYGKDCFYIKHKLKDPDAYLNPDFTEILDNINL
ALLSVSPKSHYYSGLLSRALPFLYLHLPSCIGDRVMSIMVNWFDFVPKALSQQPKSCH
>Q39J96|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MVKHMPSNVVITGASAGIGRALAIAYASPGVVLGLIGRDVARLESCAADCRARGAVVVLN
SIDVRDAEAMRVWLDCFDDEHPIDLLIANAGVASTLANSRDWEGRERTVRIVDTNFYGVI
HAVLPVIDRMKARKRGHVAMVASLAALRGMAISPAYCASKSAIKAYADSVRPLLRRDGIR
IAVILPGFVKTAMSDVFPGDKLFMWSADQAASYIRRKLGAGRAEIAFPGLLAFGMRLLPL
LPIALADAILDRLSYLPSEEDPS
>Q397V3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MRDFANKVAAITGAGSGMGRSLAIQLAQAGCQVSLADKNGVGLAETERIIRAIAPNVRVS
TRVLDVGDREAMFAWADDTAKEHGKVNLIFNNAGVALSSTIEGMEYSDLEWIVNINFWGV
VHGTKAFLPHLKASGDGHVINTSSIFGIFAQPGMSGYNATKFAVRGFTESLRQELDMMKC
GVSATCVHPGGIRTNIAQSSRVAKNMVGFIVESEQQGKDSFEKFFITTADDAARTILAGV
RKNKRRVLIGRDAKGADWMARILPSAYQALVVLATRREAAKARRGAPAPAPLHATYNNAG
NQGGEQS
>A0A8C6GI14|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus spicilegus|TrEMBL
MDPTIVLITGCSSGIGMHLAVRLASDRSQSFKVYATLRDLKAQGPLLEAARAQRCPPGSL
EILELDVRDSKSVAAAQACVTEGRVDVLVCNAGRGLFGPLEAHELNAVGAVLDVNVLGTI
RMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAILLPLFGVH
VSLIECGAVHTAFYEKLVGGPGGALERADAQTRHLFAHYLRGYEQALSEAQDPEEVTELF
LTAMRAPQPSLRYFSTNRFLPLARMRTEDPSGSSYVAAMHREAFSNLQTQENAKAGAQVP
GVSDTASSALICLPECAIPRVASELGWSASDKPGQDNSCYQQKI
>E0RPG3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Spirochaeta thermophila (strain ATCC 49972 / DSM 6192 / RI 19.B1)|TrEMBL
MAYALVTGASRGLGRAFAEELAKRGFDLLLVSLPGERLPQVADSLRRRYGIDVDALEGDI
TCSETRARIRRILSRYGHLSVAVNNAGYGHPGPFDVWDVEEWEVMLRLNVEATSALSHLV
VPFLERGRPSFLLNVASLAGFFPMPFFGVYASSKSYVLHFTLALREELKTKGITVGVLCP
GGVLTNARSIEEVRAQGLAGRLSSFPPHRVASYALEALFKGKALIIPGWFNRFLVKISSV
VPKELVAAVTGIRWRYVAHRMFHPARCSWRRRIPHPSRE
>A0A3B3Q6H0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Paramormyrops kingsleyae|TrEMBL
MDQTVVLITGCSSGIGLSLAVRLASDPSKIYKVYATMRDLAKKKRLMDCVKDSHKDTMDV
LQMDITHHQSILDVRDGIKEKRVDILVCNAGVGLVGPLESQSMEMMRQILEVNVLGTIRT
IQTFLPGMKARGSGRVLVTGSIGGLQGLPFNEIYCASKFAVEGVCESLAILLQHFNIHVS
LIECGPVNTDFLANLRRTEPGDASLSQADARTRALYATYLQHCDTMFQDAAQEAGDIVQV
RVTKGRKIPGNSPFHGKVNWGISKLFQVGNFPWELTGIYGD
>A0A3Q2YQV1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Hippocampus comes|TrEMBL
MGRCLGMKRPWWGGTIDGERQPSLVSHNVGSMDKKVVLITGCSSGIGLSLAVRLASDPEQ
TFKVYATMRNLAKKERLLESVKGLHKDTLDVLQMDVTDRQSILDARDKVAEKRVDILVCN
AGVGLMGPLEAHSLDSMKQILEVNLLGTIQTIKAFLPGMKAQRNGRILVTGSIGGLHGLP
FNVLYCASKFAIEGACESLAVLLQHFNIYVSLIECGPVNTNFLVNLTKAELGDPSLQHVD
ARTLGLYERYLHHCSYVFQNAAQDTEDIVKVFLDAMQSPSPAFRYFTSGAVPPLTELKVT
QPDGLRYISAMSKLIFSPDEQ
>A0A1Z5KBI5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Fistulifera solaris|TrEMBL
MSSIAYITEAPPLVAGLTALGLLVALSFFVKILSSTYNTFLRPGKDLKKLGKWAVVTGAT
DGIGKAYAMGLAKKGMSIVLISRTESKLKEVKKEIETKYSGIEVKHIVCDYSKFDKKAQD
DLKKQLVGLEVGVLVNNVGVSYRYPRYFHELPDDEVQNLLTMNIDSVVWMTRFVLPGMID
RKKGAIVNISSGSALYTLPLLAEYSGAKSFVEKFSRAINAEYKSKGITCQCQAPFYVATK
LAKMRKSFSVPDPNQFVGLALKWVGYPDCVVQPFWVHAVQGWVMHRVPDSILAWFIMNMH
LAIRKKGINKDLKLASEGKLE
>F9YUJ2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Capnocytophaga canimorsus (strain 5)|TrEMBL
MKLSNNTILITGGSSGIGWALAERFYELDNKVIITGRDPEKLAQIKSQYPNIETFAQDLT
QPQALDDLAAFIKENHPDLNILINNAAVQYNYLFTEERDYAQKIDYELAINLAIPMKLSV
NLLPILLKNKNSAVVNVSSGLFIAPKKTASVYCATKSALHSFSQTLRYQLESTPVKVFEI
VPSLIDTPMTQGRGKSKISPEKLVDEFIKGFKSNKYEIYIGKTKLLKFIHRIFPKVAYNI
MKNGL
>A0A075K830|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pelosinus sp. UFO1|TrEMBL
MTQKNDQVWFITGANKGLGAAIAKEALDKGYKVVAAARKTEGMEKFLGDSPNLLIVRLDI
TNDEQVQSAVNAALVRFGRIDVLVNNAGYGLLGHFEEISEKLIRQQIETNVFGTMKLTRA
VLPLMRKQGSGWIIVVSSTSGIRAVGGGSVYSASKFALEGWTEGLSMDLKPFGIRCMLVE
PGPFRTDFLNAKASCTFSDLEIDDYKQQREIMHSNYISADQNQPGDPAKLAKALMTAVNA
SNPPLRLIAGKNAVASIDQYLKERRSELKVWREVSSSTDFD
>K9PFW7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Calothrix sp. PCC 7507|TrEMBL
MQDKVIVIVGATGGIGSALTRKLAPTGARLVLTARDAVRLATLAEELPGEVLTVSCDITD
PQQVNTLIEKTVTQFGQIDVLVNTAGAGILKPYNNLEPADLDKMLDINLKGSFYTTQAAA
EEMQKRKSGHICNVVGILGKHSMPMAAAYSASKFGVVGFSKCMAEELKRFGVKFTLFYFG
GVDSPFWDNVSLKVDRKKMLSPETAANAIFFALAADPQAVPMEINIQPDSHLFF
>A0A8C2W1B8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Chinchilla lanigera|TrEMBL
MDPAERTVVLITGCSSGIGLRLAVRLAADPSGNFKVYATMRDLAAQGALWEAARARRCPP
GALEALQLDVRDSDSVAAARARVIEGRVCCPPVCNAGRGLLGPLEAHELGAVGSVLDVNV
VGTVRTVQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNAIYCASKFALEGLCESLAVLLLP
FGVHVSLIECGPVHTAFYEKLEGGLGGALDRTDARTRQLFSLYQRHCEQVAREAQDPEEV
AEVFLAALRAPQPALRYFCTERFLPLARLRVEDPSGRSYVAAMHRAVFAADPGAAEPGAA
PG
>A0A8C9YDF9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sander lucioperca|TrEMBL
MHMANCSLLKQTVGEPDSMDKKVVLITGCSSGIGLSLAVRLASDPNKTFKVYATMRNLAK
KERLLECVKSLHKDTLDILQMDVTSRQSILDARDRVVEKRVDILVSNAGVGLMGPLEVLS
LDSMRQILEVNLLGTIQTIQAFLPEMKAQGQGRILVTGSTGGLQGLPFNEVYCASKFAIE
GACESLAVLLQHFNIHLSLIECGPVNTDFLVNLQKAELGDTCLQQVDALTLSLYEKYLQH
CGSVFQNAAQDTEDIVKVFLDAIQSPSPAFRYFTSGVVPPLTRLKISEPDGKRYISAL
>Q3MEF1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MPTALITGASGGIGKAFAQELAARQTNLVLVARSQDKLHQLAQELQQQHKIQVDVIAKDL
TETDAVADVFDITKSQGLTIDCLINNAGFGDYGDFAESDRTRQIKIVQLNVLALVDLTHR
FLPLMRQSRSGSIINVASIAGFQPIPYLSVYAASKAFIVSFSEALWAENRQYGVRVLVTC
PGPTETDFFTEANFPQALAETTNKVMSSEEVVLKSLKALENWEPTVIISDTSTQLRSNVA
RLVPRKTLLSLLAKHFKA
>A0A672UL41|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Strigops habroptila|TrEMBL
MERTTVLITGCSSGIGLGLATRLATDGGFKVYATMRDPAKGERLLQRLGGRCPDTLEVLQ
LDVTDPRSLAAAAHRVQGQALDVLVCNAGVGLMGPLETCSDQDMKNVFDVNLFGAIRTIQ
AFLPAMKRRRAGRIIVSSSIGGLQGLPFNSVYCASKFAVEGLCESLAIVLRPFNIHLTLV
ECGPVNTSFLSNLQCPDPDGSELQGLDAETRGLYRRYLRHCQGLFRDGAQEVEEVLQVFL
EAMGSPCPPLRCATTQLLAPLARLRLTDGSAYVQAMHDFVFGRGEAGGDQP
>K0Q3G7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhizobium mesoamericanum STM3625|TrEMBL
MFLFYEGGMQSPSFPELSGKRAIVTGGATGIGRAIATALSRQAVQVAICDINLAAAERTA
AEIGKGTTAHAIDVRKRASVEATFSEVAEKMGGYDILCANAGVSTMQHALELTDEEWDYN
FDVNIRGIFLTNQIAARRFTSAGTGVIVNTASLAAKIGAPLLAHYSASKFAVLGWTQALA
RELAVSGIRVNAVCPGFVKTGMQEREIAWEASLRGVTPERVVADYIAQTPLGRLETPEDV
ADVVVFLCSNSARFMTGQGVNVTGGVYTT
>G4I0U7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mycolicibacterium rhodesiae JS60|TrEMBL
MSEKVWFITGTSRGFGREWAIGALERGDKVAATARDTATLADLVSTYGDAVLPIQLDVTD
RVADFAAVKQAHEHFGRLDVVVNNAGYGHFGFIEELSESDARDQLETNVFGALWITQAAL
PFLRAQGSGHIIQVSSIGGITAFPLVGIYHASKWALEGFSQALAAEVAPFGIHVTLIEPG
GFDTDWSGPSSKRSVELPDYAELHRQVDEMRAKRWAKPGNPQASASAILTIVDAPKPPLR
AFFGESPLATAKADYESRLANWEEWQPIAVQAQG
>A0A8B6DQ29|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mytilus galloprovincialis|TrEMBL
MKRLRKVAVITGGNSGIGLSVCERLLTLHNNLELCLLCRNKHRAEAAKNALLVSHPQSSI
TIVIMDTSDVKSVFKAAQDLRQRYEGIDYLYLNAGIMPVTGVNWTNVVKGVLSSNCAHVL
STGEGCLYHTDETTKDGLKNIFASNLFGHYTLIKELEDRLGGDKDTQIIWTSSRAAMKSA
FNITDIQHKNGENPYSSSKYLIDTVSVSLNNKLNKKRVYSHTTCPGLVMSNLTNGVLPYW
IWSIIYPLLIMLRLFCPSLTCSSYIGSEAMVWLSTQNPQSLDPQDKFNSDVDIFGKTHVS
IVKLDIDTKTEETVCSKLDELYKEFKTKYY
>A0A7M4DXL1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Crocodylus porosus|TrEMBL
MQGTAPSKICAMEKTVVLITGCSSGIGLGLAVRLASDSSQRFKVFATMRDLAKKERLLEC
VRGCHRDTLEILQLDVTNPASLASAIQRVPEQRVDVLVCNAGVGLMGPLETCSQEAIKAV
FDVNLFGTINTIQAFLPGMKCRKAGKIIITSSVGALQGVPFNAVYCASKFAVEGLCESLA
IVLQEFNIYITLIECGPVNTSFLSNMQSMDPEGHELQGLDPKTYALYRQYSQHCQSLFQD
AAQDTDEVLQVFLDAICTPNPPLRCFTTQFFMPLTRLKLLSPDGSEYVQAMHKFVFSTSK
PQEDQA
>A0A8C3HS68|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Chrysemys picta bellii|TrEMBL
LACTVVLITGCSSGIGLGLAVRLASDASRRFKVYATMRNLAKKERLLECVRGCHASTLEI
LQLDVTDPLSLAAAAQQVQEQRVDVLVCNAGVGLMGPLETCSFQAMKTIFDVNVFGTIGT
IQAFLPGMKRRKAGKIIISSSVGALQGIPFNAVYCASKFAVEGLCESLAVILQQFNVHVT
LIECGPVNTSFLANLQRTDAEGSALQGLDPQTRALYSQYLQHCQSLFRDVAQDTEEVLQV
FLEAICAPCPPLRSFTTQFFMPLTRLKLTSPDGSEYVRAMHKFVFSAGEAQGDQA
>A0A3Q0RYH8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Amphilophus citrinellus|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPDKTFKVYATMRNLAKKERLLESVKDLHRDTLDI
LQMDVTDWQSILDARDRVVEKRIDILVCNAGVGLVGPLEVQSLDSMRHILEVNLLGTIQT
IQAFLPKMKAQNQGRILVTGSTGGLHGLPFNEVYCASKFAIEGACESLAILLQHFNIHVS
LIECGPVHTDFLVNLQKAELGDTSLQQVDTQTLKLYEKYLQHCSSIFQNAAQDTEDVVKV
FLDAIQSPSPAFRYFTSSAGPPVTKLKVTEPDGSYISAMSKVIFSGEEQQFCS
>Q397S1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MSKVWFITGASSGFGRALAEAVLAAGDNAVLAARRGDALDAIVGRHGDRALAVSMDVTNA
DARQRAVRAALERFGRVDVLANIAGRGSCGAAEEFSGEQLREQLELNFIAPVELTREVLP
HMRARGTGHILNLTSIAGLAPIPACALYCAAKFALEGWSETLHQEVGPLGIRVTIVEPGG
FRTEFNGAAIMRPGQTIDAYRPTVEPILQFLESESGRQPGDPDKAARLMIEAVNSDTPPL
RLMLGADAYQLWEKTAAARDADISAWREKGEATAYDDAQLTPIGGA
>F6DGM5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Thermus thermophilus (strain SG0.5JP17-16)|TrEMBL
MRLAGKVVVVTGAGSGLGQALTLELLKRGARVAAVDLKEEGLRETQAKAGGLSEGLSLHP
LDITDRPKVQALPEAVEKAHGQVDGLINNAGIIQPFKRLLDLEEAAIERVMRVNFFGTLY
MTRAFLPRLLTRPEAHLVNVSSMGAFVPVPGQAVYGASKAAVKLLTEALWAELQGTSVRV
TLALPGAMRTGIAAHSGVETPGAGEARGPILEPQEAARILLDAVERDAFRVLLGKDARTM
DLLYRLSPLYATRLIQRRMAHLLARG
>A0A0H3KRW3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia multivorans (strain ATCC 17616 / 249)|TrEMBL
MKDFANKVAAITGAGSGMGRSLAVQLAQAGCHVALADKNGVGLAETERIVRAIAPNVRLS
SRVLDVADRDAMFAWADDTAREHGKVNLIFNNAGVALSSTIEGMDYADLEWIVNINFWGI
VHGTKAFLPHLKAAGEGHVINTSSIFGIFAQPGMSAYNATKFAVRGFTESLRQELDMMKC
GVSATCVHPGGIRTNIAQSSRIAKNMVGFMIESEQQGKDDFEKFFITSADDAARTILAGV
RKNKRRVLIGRDAKAADWMARILPAAYQALVVLKSRQEAAKARRRAARFGTPASAPLHAT
YNNAGNQGGKQS
>A0A8I3NC11|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Canis lupus familiaris|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSRSFKVYATLRDLGTQGPLWEAARSRGCPPGSL
ETLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLEAHAAGAVESVLDVNVAGTV
RTLQAFLPDMKRRGSGRILVTGSMGGLMGLPFNAVYCASKFAVEGLCESLAVLLTPFGVH
VSLIECGPVRTAFLEKLEGVPGGVLDGADAKTRHLFSSYRRHSEQIFREAAQDPEEVTEV
FLTALRAPRPALRYFSTERFLPLAHLRLADSSGRSYVAAMHRAVFADQPAEEAAAATRPP
APGAPPAAPQ
>F0NYK6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Weeksella virosa (strain ATCC 43766 / DSM 16922 / JCM 21250 / CCUG 30538 / CDC 9751 / IAM 14551 / NBRC 16016 / NCTC 11634 / CL345/78)|TrEMBL
MKRTAFITGATSGIGRATAEILADNYRLILCGRREERLDEVKKELEHKTEITTLQFDVRD
RKSVFKALDHLDKNWQTIDVLVNNAGNAHGLSTFDEADLDDLEAMIDINIKGLIFVTKAV
LPFLKESKNAHIVNLSSIAGKEVYPLGATYCASKAAVESLSKGMRYDLLPYGIKVSNVAP
GAVETEFSLVRFKGDVERAKKVSKAIIRFSQKISQMQFYIY
>I6UDT4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Passer domesticus|TrEMBL
GLAARLAADAARRFQVYATMRDLAKGERLLERLGGCCPDTLELLQLDVTDPCSLAAAAQR
VQGQRLDVLVCNAGVGLMGPLETCSDQAMKTLFDVNLFGAVRTIQAFLPAMKSRRAGRII
VSSSIGGLQG
>A0A3Q1FRJ3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Acanthochromis polyacanthus|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPDKRFKVYATMRNLAKKERLLECVKGLHKDTLDI
LQMDVTDRQSILNARDRVLEKRVDILVCNAGVGLMGPLEVQSLDSMRKILEVNLLGTVQT
IQAFLSNMKAQGQGRILVTGSTGGLHGLPFNEMYCASKFAIEGACESLAVLLQHFNIHVS
LIECGPVNTDFLVNLQKVELEDASLQQLDTQTLSLYEKYLQHCSSVFQNAAQDTDDIVKV
FLDAIQSPSPAFRYFSTSAVPPLTKLKMTEPDGSQYISAMSKIIFSAEEQ
>A0A3B4FV08|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pundamilia nyererei|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPDKTFKVYATMRNLSKKERLLESVKGLHRDTLDI
LQMDVTDRQSILDARDRIVEKRINILVCNAGVGLMGPLEVQSLNSMRHILEVNLLGTIQT
IQAFLPQMKAQSQGRILVTGSTGGLHGLPFNEVYCASKFAIEGACESLAILLKHFNIHVS
LIECGPVNTDFLVNLQKTELGDTSLQQVDTQTQRLYEKYLQHCRSVFQNAAQDTEDIVKV
FLDAIQSPSPAFRYFTSTTGPPVTQLKVTEPDDSYISAMSKIIFSPEEQ
>H2UPG6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Takifugu rubripes|TrEMBL
MDAKVVLITGCSSGIGLSLAVRLASDPQKAFKVYATMRNLSKKERLLESVKGLHKDTLDI
LQMDVTSQQSILEATARIVEKRIDILVCNAGVGLMGPLEVQSLESMRKILEVNLLGTIQT
IQAFLPDMKARGKGHILVTGSTGGLHGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLANLQKAEVGDMCQNLDKQTLALYEKYLQHCDSVFQNSAQDTEDIVKVF
QDAIQSPNPAFRYFTSDVVPPLTKLKVTEPDGSRYISTMSKIIFSTEEQ
>K9PRE5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Calothrix sp. PCC 7507|TrEMBL
MSTALITGASGGIGKAFAQKLAARQTNLVLVARSEEKLNQLAQELQEKYKIRVDVIVKDL
TETNAANAVFDVTKSQGLTIDLLINNAGFGDYGDFAERDGERQVKMVQLNILALVDLTHQ
FLPLMRQRRSGSIINVSSIAAFQPIPYLSVYAASKAFVLSFSESLWAENRQYGVRILVAC
PGPTETDFFTEADFPQSFTGKTSKISTPEEVVNDTLNALERGDSTVVSGSFLSKIITNLS
RFVPRETLVSILEKQFKA
>A0A2K6GJC4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Propithecus coquereli|TrEMBL
MERTVVLITGCSSGIGWHLALRLASDPSRSFKVYATLRDLKAQGPLWEAARARGCHPDCL
ETLQLDVRDSDSVAVARSRVTEGRVDVLVCNAGRGLLGPLEAHAAGAVSSVLDVNVAGTV
RTLQAFLPDMKRRRSGRVLVTGSMGGLMGLPFNAVYCASKFALEGLCESLAVLLPPFGIH
VSLIECGPVRTAFQDKLEGGPGGALDGTDAQTRHLFSLYQRHCEQVFREAAQDPEEVTEV
FLTALRAPRPALRYFSTERFLPLARLRLDDSSGCSYVAAMQRAVFADEPAEAGAGGPGGP
EPGAPPAAPQ
>G0R5R1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ichthyophthirius multifiliis (strain G5)|TrEMBL
MSNSKKQIQKKSVYTIIILYSFVHTSKNKRFTPKKSIRGKHILITGAGSGIGRQMSILLA
KLGAKISILDLNIQGAEQTQQIITQLGYQDQTKAFKCDVSDINDVKTHSNKLKTSTEVSI
FSQTTPGQYLVRKYQKQAINKLSKQLQQTPFRTHIQQDKFYRKCFKEIQDIQSQQHLLQD
ILELPVQLIIAQANLGQSVLMKVLEWKCQNQERIQKQRVFVHILLILECLMELKVNSRYF
YQFQRKNGHHKGLQMQFYKRKKQLLCHGFQIFV
>F6A8X2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pseudomonas fulva (strain 12-X)|TrEMBL
MNTASKGTALVTGASSGIGALYAERLAQRGYDLILVARNRDRLNDLARRITDDTQRVVEV
LQADLGDATSLATVEAKLKQDASITLLVNNAGIGTHTPLLASDVGLMTRMIDLNVTALMR
LSYAAIPGFVERGNGAIINISSIVSITPEVLNGVYGGSKAFVTAFSQSLHHELADKGVRV
QAVLPGATATEFWDNGGLPLEHLDPSIVMPASALVDAALIDFDRGELISIPSLHDASQWQ
AYEAARKAMFNQLSTNQPAPRYSAQR
>A0A4W4DN23|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Electrophorus electricus|TrEMBL
MEQKVVLITGCSSGIGLSLAVHLASEPSKAYKVYATMRNLDKKQRLLESMRGLHKETLAI
LQMDVTDQHSILSARDSISEGSVDILVCNAGVGLMGPLETQSEDTMRGILDVNLLGTIRT
IQTFLPDMKRRRTGRILVTGSMGGLQGLPFNEVYCASKFAVEGTCESLAILLQHFNVHVS
LIECGPVNTDFLRNLTKTEVGDGSVEVDAHTRSLYETYLHHCQTVFQNAAQDTDDIVKVF
LEVIRCPCPGLRYYTSSAMLPLSSLKLTAHDGSQYVRAMGKLVFSAGSTDSQN
>Q3MHS3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rattus norvegicus|TrEMBL
MNSKQQTVRLSDGHFIPVLGFGTYAPREVPKSKALEATKIAIDAGFRHIDSAAVYQNEKE
VGLAIRSKIADGTVKREDIFYTSKVWCTFNHPERVQVCLEQSLKQLQLEYVDLYLIHFPM
ALKPEEDLKAKDENEKLLFDVVDICDTWKAMEKCKDAGLAKSIGVSNFNRRQLEKILNKP
GLKHRPVCNQVECHPYLNQRKLLDFCKSKDIVLVAYSALGSHRETRCVDKSLPVLLADPV
LCAIAKKYNWTPALIALRYQLERGVVVLAKSFTEKRIKENMQVFEFQLTSEDMKVLDGLN
KNIRYMSGSRFQGHPDFPFLDEY
>A0A2A9I9T8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Lactococcus lactis|TrEMBL
MTQKIVAITGASNGMGFEAAELFAKRGWKVYAGARRVEKIPQYENNIKALKLDVTSSESN
QAFVKKILDEAGHIDVLINNAGYGEYGPAEEIPMDKIRNQFETNFFGAVELTQLVLPTMR
AQNYGRIVNISSIGGDVYMPLGAYYHATKAALQQWSDVLDLEVAQFGIRSVCVQPGGTQS
SWGNIALENSKKNMSSNSAYQPLVNSVASGLDRFMKNSAKASDLAEVFYKAATEIKPSLR
YLHSFGDKFMVNVARKHPKIFRKALLITMRYFEKHNQ
>Q9W4U2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MSVGVLAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQELGSERSAAL
EVDVSSAQSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPERDYDDVYGVNLKGTF
LVTQAYAKAMIEQKLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFG
IRVNCILPGYIDTPMVAVVPDSVKQEVVQRCPLGRLGQPEEIAEVIAFLASPQSSYVNGA
AIEVTGGLK
>Q5LJT3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MERWHDRVAVVTGASSGIGAAVARHLVSAGVIVVGLARRVDRMKAIKEQLPPELQGRLHA
IHCDVEDLDSVTAAFDWIEEQLGGCDILVNNAGCLNPGQLLTLELEQLQQVLNVNLMGVV
ICTRRAFRSMQQREVDGHVILINSLTGRNIINPPGDELQVLNMYPLTKHGVTAMLEVLRQ
ELRGFKTKIKVTSITPGVTDTEILPSGYGILPMLKPDDIAAGIMYVLGTPAHVQVHELTI
KPLGEPF
>Q8SX57|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MSSFKDKVIIVTGASSGIGASAAVHLAKLGGLLVIVGRNEEKLKETADNIVAAGGATPLE
LQADMTKEAEVQQIVGATLAKHGRIDVLVNNAGILETGSIEATSLEQFDRLMNTNVRSLY
QLTMLATPELVKTKGNIVNVSSVCGLRAFPGVLAYNVSKAAVDQFTACIALELAPKGVRV
NAVNPGVIVTDIHKRGGMDEETYAKFLEHCKITHALGRPGDVKEVAAAIAFLASDQASFT
TGISLPVDGGRHAMCPR
>F6F3A1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sphingobium chlorophenolicum L-1|TrEMBL
MTEVQGRTAFITGGAHGIGLGIARALAADGVKVALADLDANALSLCKAELASITEVETVR
LDVRDRQGFVEAIDHVEESLGPVTLLINNAGVAGSGDIDDLDYALWEWNIGINLWGVING
IQSVLPRMRARGLGGHVINTASASGLVGGTATMAYCTAKAGVVGLSESLRTELKGSGIGV
SVLCPGPVATSILTHSAENLASVSVSRPVPSAERRDAQMSNVLEKAIQPDEVGRRVLAAI
RANQFYIHTDRVMLQALEDRHREIVDAMPDEEMSLFTAELSAAFSRRRAS
>F4CCD9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sphingobacterium sp. (strain 21)|TrEMBL
MNDRENTGRYALITGGTSGIGLELAKLFAENDYNLVLVARNEQELVQTAAELRTNGREVI
TVVADFFNPDAPFSVYEEVKAYGIDIDVLINNAGQGVYGKFIETELQRELDIIHLNISAC
VVLSKFFVKDMVQRGYGKILNLSSIAGKIPGPYQAVYHGTKAFVHFFSEAIRSELKDTGV
TVTSLLPGATDTDFFRKADMEESKIVQEQELADPAFVARKGYEALMKGEDMVVAGFKNKM
QVAMGNLSTDEAATERMGNMQKPTDQ
>A0A8C4W4L2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Gopherus evgoodei|TrEMBL
MEKTVVLITGCSSGIGLGLAVRLASDASRRFKVYATMRNLAKKERLLECVRGCHASTLEI
LQLDVTDPLSLAAAVQQVQEQRVDVLVCNAGVGLMGPLETCSYQAMKNIFDVNVFGTIST
IQAFLPGMKRRKAGKIIISSSVGALQGIPFNAVYCASKFAVEGLCESLAVILQQFNMHIT
LIECGPVNTSFLANLQHSDTEGSALQGLDPQTRTLYSQYLQHCQSLFRDVAQDTEEVLQV
FLEAICAPCPPLRSFTTQVFMPLTRLKLTSPDGSEYIRAMHKFVFSAGEAQGDRTLSVPP
MGDPPGCSGGWCNRHWTPSPSMAQGPGVERGGEVQGVVFHFSLGPEGWPQVWD
>I3IY18|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Oreochromis niloticus|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPDKTFKVYATMRNLSKKERLLESMKGLHRDTLDI
LQMDVTDRQSILDARDRIVEKRINILVCNAGVGLMGPLEVQSLNSMRHILEVNLLGTIQT
IQAFLPKMKAQSQGRILVTGSTGGLHGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLVNLQKTELGDTSLQQVDTQTLRLYEKYLQHCRSVFQNAAQDTEDIVKV
FLDAIQSPSPAFRYFTSTTGAPVTQLKVTEPDESYISAMSKIIFSTEEQ
>W3ZXT1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhodococcus rhodochrous ATCC 21198|TrEMBL
MGSRIAEMRRWRAGTVVHQRLHDLTGTLAVVTGAGSGIGRATARAFSDVGAIVVVADRNL
DTARETAEMLNTPDPQAGGSRAVYGGGAHAYELDVADEEQVRRFAATVRSQHGVPDVLVN
NAGIAVIGTFTGTPQETFEHVMDVNFWGVVYGCRAFGDQMLERGTGGHIVNVASAAAFTP
QKSLVAYSTSKAAVLMFTDCLRAELMGHGIGVSAICPGLVGTNLVPSAEMVGLGVREQRK
LRERVTALYRTRSYPPQKVGEAIVAAVRHNRALVTVMPEAKARQWISRLAPPAMRFGARF
EPDR
>W4A5J4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhodococcus rhodochrous ATCC 21198|TrEMBL
MTLPNPTPDARAVVTGASSGIGEALAAELAARGHSLILVARRGDVMEELAATLRATHGVT
VEVRACDLSDRDARAKLVDELGERPISILCNNAGIATFGPVAQLDPGYERAQVELNAVAV
HDLTLAVLPQMVERRSGAILMVGSAAGNMPIPHNATYAATKAFVNTFSESLRGELKDSGV
HVTLLAPGPVRTETPDPAEASIVDKLVPDFLWISSEHTAKVSLDALAENKMRIVPGLISK
AMSVAGNYTPRGVVAPIVGAFYRKLGA
>A0A087A0C9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bifidobacterium biavatii DSM 23969|TrEMBL
MVRMDAIKDDGRAVALVTGGTSGIGRATAELLARHGWRVVAVGLDAVKIAHVQRLDGVDG
ACGGELITEEMDVTKPDDIRAVVGALPRLDAIVHCAGFGIAGSAECTPMELVRRQFDVNY
FGVLQVDEITLPLLRRTASRNRRRGRVIVVGSIGGRIGLPFQSHYSSTKAALEMYVEALR
LEGRRHGITATIIEPGDLATGFTGARVTAEPTNSPYLAECRRSVGQMAHDEQTGAGPDTV
AQVIAATLARRNPPVRVAVGGSYKALMQLKRFLPDRAVEFIMRCIYMK
>A0A1Y6KCY2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bradyrhizobium sp. ORS 285|TrEMBL
MDQATQPRIIGHGLRPVADNVWIVDAGRINAAGLPLPVRMTVIRLSSGDLLLHSPTRFSH
ALREELEQLGPIKYLLAPNVAHWMFLPDWQAALPNAKVYAAPGLADRSQVRRSGLRIDRE
LTDVTPDEWSEDLQLVLVTAPMFTEVAVFHRPSRTLVLTDLVQNLAPEGLGIPSRAAAHL
LGITAPDGKAPAYLRLLLRLGGRAVQLAAARLIALAPERVIFAHGRWFETGGTQQLRHSL
GWLLDGSPEARRLMRDLRGKRVVITGASSGIGRATALALAREGASLVLAARREDVLKDVA
AECETFGGRAVAVGTDVTNADAVKQLAERAVQTFGGIDVWINNAGTGVFGAYQDADIALH
RKTIEVNLLGTMNGAYAALPVFLRQRRGTLINNISLGGWAPTPFAAAYTASKFGLRGFSA
SLRQELAAHRDIHVCSVFPAMVDTPGFVHGANVSGRNLDPGPLLYRPEDVAETFVQLIRA
PHDEVAVGWPARLGQISYALARWPTERFMSTAFRFLLSRAKIAPRSSGAVLAPIPAGTSV
SGGWLARKKLPAAGQLSKIGLAVGIGGMALLLATRSRAARPSPRKRSHR
>Q1LFC2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)|TrEMBL
MHSKVALVTGASSGIGEATALKLLAQGYTVYAAARRVERMRSQADAGVHVLAMDVTDDAV
MRAGIEEIIAKSGRLDVLVNNAGYGAYGAIEDVPLDEARAQFDVNVFGAVRLIQLALPHM
RAQRSGTIVNITSMGGKIHTPMGAWYHGTKFALEAISDCLRMEVEPFGIDVVVIEPGGIK
TEWAGIAAENLLKVSGTGSYAPQASAMAKLMINEANGNRQSPPQLIAETIAKAVNAARPK
TRYAVGFGARPMILMRRLLSDRAFDSLMRMAARMPRSAQRRSCGAAS
>A0A452FZA7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Capra hircus|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASHPSQSFKVYATLRDLASQGPLLEAAQSRGCPPGSL
ETLQLDVRDADSIAAAQARVTEGRVDVLVCNAGRGLVGPLEAHKEGSVDAVLDVNLTGTV
RMLQAFLPDMKRRRSGRILVTGSIGGLMALPFNAVYCASKFALEGLCESLSILLQPFGVH
VSLIECGPVHTPFPEKVEGGLGGMLDRADAETRDLFYRYCRHCERVIREAGQDPEEVVEV
FLQALRARRPALRYFTTERFLPLVQLRFSDPSGSSYVAAAHKSAFHDVAAEGSDDGNTRP
PDLPPEKSVCRSGSNS
>A0A493T5K6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Anas platyrhynchos platyrhynchos|TrEMBL
MEQTTVLITGCSSGIGLGLAARLAADSARRFKVFATMRDLAKSERLQERFGGGCPETLEL
LQLDVTDPRSLAAAAQRVQGQRLDVLVCNAGVGLMGPLETCSEQAMRTVFEVNLFGAIRT
IQAFLPTMKRRRAGRIVVTGSVGGLQGVPFNSVYCASKFAVEGLCESLAIVLRPFNIHVT
LVECGPVNTGFLQNLQRADPEGSELQGLDHETRSLYRRYLRHCHGLFRDAAQEVEEVLQV
FLEAISTPCPPLRCATTQLFAPLARLKLASPDGSDYVRAMHDFVFGPGDDGGDQP
>F0SPC3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MQFKNRWALITGASSGIGAEFARQLAARGMNLLLSARRVERLESLAEELQSKFGIQTEIC
AADLGKPEDCEALITRTRELPEPLFLLVNNAGLGNVAKIEQTEPERMLQLVDVNVRSLTQ
LTYAFLPAFVQRNEGAIINIASVAAFQPIAYMSVYAASKAYVLHLTEGLQAELAKSAVRL
LAVCPGTTRTEFFDEAGADNWLQERRSHTPEQVVTASLKALEKGKTICIPGWMNRMMTTM
PRFFSRKAVAKETKRFFKSAVES
>A0A139XT13|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii ARI|TrEMBL
MESLARRLCVYTLTWLAILGDADDLLQASRYKRDGSFLVPPHIWHVETAACRWMIHQRPN
VFRRLEADLRTESAFVGANHSQSWGDALDACWSSSSFVSRALCLGIASFRGAAFALSAFN
SWREREKAQERKLAVLVTGSSSGIGLQVTRLLLALDFYVIGTRLHSEDPRRVFEEICRGN
SRLLLLPMDVTNAEDVARAVEATKKFLRENDVSGLYALVNCAGIWNWNFIQTQSPQETEK
SLKSWRELFDVNLLGAVRVMHAFLPLMQARAVFVGSILGRMSSPGQTAYCASKAAVRLLA
EGARSDARDAGVNVVLVAFLAEVRVAPAQHVKSSTCVFAKETLTL
>A0A667X564|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Myripristis murdjan|TrEMBL
MDQRVVLITGCSSGIGLSLAVCLASDPDKTYKVYATMRNLAKKERLLECVKGLHRDTLDI
LQMDVTNQQSILEAKDRVTEKRVDILVCNAGVGLMGPLEVQSLDTMRQILEVNLLGTIQT
IQAFLPGMKAQRQGRILVTGSMGGLHGLPFNELYCASKFAVEGACESLAILLHHFNIHVS
LIECGPVNTDFLNNQQKTELGDASLQQVDAQTLSLYEKYLQHCGAVFQNAAQDTEDIVKV
FLDAIQSPSPALRYHTNDAMSPLTTLKTTAPDSSQYISAMSKLIFSSNSAEDQ
>A0A8C9CDD5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Phocoena sinus|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSQGFKVYATLRDLMAQGPLWEAARSRGCPPGSL
EMLQLDVRDADSIAAARARVTEGRVDVLVCNAGRGLVGPLEAHEEGAVGSVLDVNLTGTV
RMLQAFLPDMKRRRSGRILVTGSVGGLMALPFNAVYCASKFAIEGLCESLAILLQPFGVH
LSLIECGPVHTAFPEKLEGGLGGVLDRADAETRGLFSRYLIHSEQIFLEAGQDPEDVTEV
FLQALRAPRPALRYFTTERFLPLIQLRFSDPSGCSYVAAAHQAVFGDQAAEGSDGAGAEP
GAGEPGAPELGAPLAAPK
>A0A087E0D5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bifidobacterium stellenboschense|TrEMBL
MDIAVVTGASSGLGKAFIEAIVARYRNLDEIWIIARREQRLRVLAERYCNPKTRIRVVPL
DLTKTDAHERLIGLLKDERPDIRVLINNAGYEREGLLREMRSDDIRAMIDLNVTAVTMIN
RICLPYMRNGSFEVITGSVSSFAPIPWQTVYAASKAYVRFLARALHEEERTRGVNVMLFS
PGNMDTEMNVRGAASGKLARLPYLDLHRETGKVLAKAERGCAEYTPLVFYKLYRLFAKLA
PSALAVRVDSFETGGAGGGSTR
>A0A3Q2PCE1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Killifish|TrEMBL
MSVDQKVVLITGCSSGIGLSLAVRLASDTGKAFKVYATMRNLAKKKRLLESVKGLHQDTL
EILQMDVTDRQSILNARDKVVEKRVDILVCNAGVGLMGPLEVQSLDSMRHILEVNLLGTI
QTIQVFLSDMKAQGQGQILVTGSTGGLHGLPFNEVYCASKFAIEGVCESLAVLLQHFNIR
VSLIECGPVNSDFLVNLQRAELGDACLQQVDGQTLSLYEKYMQHCSTVFQNAAQDTEDIV
KVFLDAIHSTNPAFRYFTNSVMPPLTKLKVTEPDGMKYIKAMSKIIFADEDQ
>A0A3Q2PCE1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Fundulus heteroclitus|TrEMBL
MSVDQKVVLITGCSSGIGLSLAVRLASDTGKAFKVYATMRNLAKKKRLLESVKGLHQDTL
EILQMDVTDRQSILNARDKVVEKRVDILVCNAGVGLMGPLEVQSLDSMRHILEVNLLGTI
QTIQVFLSDMKAQGQGQILVTGSTGGLHGLPFNEVYCASKFAIEGVCESLAVLLQHFNIR
VSLIECGPVNSDFLVNLQRAELGDACLQQVDGQTLSLYEKYMQHCSTVFQNAAQDTEDIV
KVFLDAIHSTNPAFRYFTNSVMPPLTKLKVTEPDGMKYIKAMSKIIFADEDQ
>A0A7U3ZL30|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Runella slithyformis (strain ATCC 29530 / DSM 19594 / LMG 11500 / NCIMB 11436 / LSU 4)|TrEMBL
MSSKIILITGASTGFGNITAKLLAQNGHTVYATMRNINGHNKPQKDALLSWAKTQKVDLR
VVELDVTSDDSVEKAKKQILEETGGSIDVIINNAGIYGGGIQEAFTVNDYKALFEVNAFG
SVRINNAFLPTLRKQGSGLIIQTSSVLGRIIIPFGGVYNATKWAVEALSENLAYELKPLG
IDVAIVQPGAFPTELFQKFYPPGNLDVAAEYGKSAELLNTSSQTIMAMMADSNIPNKPEQ
VAAAIVKLIEMPKGTRPLRTVVDKMMGGVTEIINETAKQVQAEVLQNFGLSELNINN
>A5AAH5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Aspergillus niger (strain CBS 513.88 / FGSC A1513)|TrEMBL
MTQRQQTWLITGSSSGLGASLAIAALKAGHKVLATARNPTTASAQNPQITSLGGIWISLD
VNDPSTPNKIQSAINTHADGIIDVVVNNAGYSLLGSIEDMSESEIESQFSTNVYGPIRVL
KGVLPFMRKRRAGTVVNISSSAGVDGAPGCAVYAGSKFALEGMTESLSKELRPFGIRVLL
VEPGYFRTKFFSAFVQPAAGLTEDYVGTPVEAALKLIKSKDGNQEGDPEKAALRILEVVM
GTGMAADITDKGFLRVVLGPDCWKRFSGKIDGVRENLEAMREIAHSTSFEE
>A0A6I8NW39|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ornithorhynchus anatinus|TrEMBL
MARTVVLITGCSSGIGLHLALRLAAHPSRSFKVYAALRDPAAQGPLWEGARARGCPPGSL
QTLPLDVTDPGSVAAAKAAVSEGRVDVLVCNAGRGLVGPLEAQTTGAARQVLDVNVLGSV
HLLQAFLPDMKRRRAGRVLVTGSIGGLQGIPFNAVYCASQFALEGLCESLAVLLLPFDVH
AARCARPCRRSRRGGPGGVLGDADPETRALFARYLQHSERLFREAAQEPEEVVEVFLAAL
RAPRPALRYYSTERFLPLARQRLEDPSGSRYVAAMHRFVFEEEPGAGGLSPLEPPRPTPS
VSLGPWSLFSGPGRDRGWKG
>A0A663DR05|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Aquila chrysaetos chrysaetos|TrEMBL
GQGTRVPKTTVLITGCSSGIGLGLAARLAADTARRFKVYATMRDLAKGERLLKRLGGCCP
DTLEVLQLDVTDPCSLAATAQRVQGQRLDVLVCNAGVGLMGPLETCSDQAMKTIFDVNLF
GAIRTIQAFLPAMKRRRAGRIIVSSSIGGLQGLPFNSVYCASKFAVEGLCESLAIVLRPF
NIHLTLVECGPVNTSFLANLQRPDPEGSELQGLDAETRGLYHRYLRHCQSLFHDAAQEVE
EVLQVFVEAIGTPCPPLRCVTTQLFAPLSRLRLASPDGSAYVRAMHDFVFGRGEAGGDKP
>F4CAL1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sphingobacterium sp. (strain 21)|TrEMBL
MAKTIFITGATSGFGKLWAEALLQRGDNVAATSRRANAFTALSEKYGDQFLPLQLDITDR
EAVFATVDKAKEHFGQLDVVINNAGYGVFGAVEEVREKVARDVFDANLFGTLWVTQAALP
ILRAQAHGHIIQLSSVLGVWSLPTLGIYNATKFAVEGLSEALASEVKDFGIHVTLIEPNG
YKTEFGGSSAVFGDSLDVYNPLRESLGKIEGLGPDDYGTPEATVPAILKLIDSENPPLRL
FLGKLGYVKTERVYGEKLQQWKEWKDVSEAAHG
>B9RM44|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ricinus communis|TrEMBL
MLLLLFGFPALLLFFVFLYKFLTSDGDFTLISKKHVRREEIEDKVVWITGASRGIGEILA
KQLASLGAKLILSSRNEAELERVKNQLKGKHAPDEVKILPLDLASGEDSLKEAVEKAESF
FSGAGIDYMIHNAAYERPKSTALDTTEESLKATFNINVLGTLSLTRLLAPFMLKRGRGHF
VVMSSAAGKVPAPGQAVYSASKFALNGYFQSLRSELYQKGIRVTIVCPGPVDTSNGYGVA
TSERKSSEKRVSSERCAELTIIAATHGLKEAWISYQPVLAVMYLVQYMPSIGYWLMDKEI
CQVSFRRQETTQHYIRSHCNWAWGLVLGAYLSLYQKGYHLE
>G8NWP5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)|TrEMBL
MSNSTGNTQAGKVWFITGASTGFGREMAEQLLAGGAKVVATARKPEQLSALAAKYPETAL
VLPLDVTKEDAVQSAVEKTLAKFGHVDVLVNNAGYGVLGAVEEVTEAEFMPMYETNVFGL
IRVTKAFLPQFRARRSGHIVNLSSIGGLVGLSGWGFYNSTKFAVEGFSEALSVELAPLGV
KVLIVEPGPFRTDFLGRSGQEVPTRIADYDETAGKTREYMKTNDGKQVGDPVRAVQAIIA
AVASPHTPKHLLLGKLALTRFRAKLDEFTQEIAAWEPVTLGADFPEGE
>A0A086L8L4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii FOU|TrEMBL
MESLAWRLCVYTLTWLAILGDADDLLQASRYKRDGSFLVPPHIWHVETAACRWMIHQRPN
VFRRLEADLRTESAFVGANHSQSWGDVLDACWSSSSFVSRALCLGIASFRGAAFALSAFH
SWREREKAQERKLAVLVTGSSSGIGLQVTRLLLALDFYVIGTRLHSEDPRRVFDEICGGS
TRTPEGGAEPRPAAAGERPRREETEEREDERERERKEDSRLESGESGETIGQTKQDGAEH
RRRWRGSRTQSRRPAEAREGADRSRLLLLPMDVTNAEDVARAVEATKKFLRENDVSGLYA
LVNCAGIWNWNFIQTQSPQVRTAQKKLFGFLFAFISRCVYSQ
>A0A2P6Q8W2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rosa chinensis|TrEMBL
MAAASSCPAIIPWEKHDVFLSFRGEDTRDTFTSHLYEALCQKKIQTCIDYKLERGDEIAP
ALLEAVSELKLSVIIFSKNYASSTWCLDELVHIL
>F7G656|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Monodelphis domestica|TrEMBL
MERKVVLITGCSSGIGLHLAWRLAADPSGSFKVYATLRDLRAQGPLWEGARVRGCPPGSL
ETLQLDVTDPSSVASARDQVSEGRVDVLVCNAGRGLLGPLEAHEMEAVGSVLDVNVVGTV
RMLQAFLPDMKRRGTGRVLVTGSVGGLMGLPFNAVYCASKFALEGLCESLAVLLLPFGVH
ISLIECGPVRTAFQEKLEGGPGGVLGSADLDTRALFSRYQRHCERVFREVAQDPEDVVEV
FVQALCAPRPVLRYFSTEHFLPLAGLRFSDPGGSQYVEAMHHAVFTELEEGEAQSGSFHP
EASPQ
>A0A8C3HS61|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Chrysemys picta bellii|TrEMBL
MEKTVVLITGCSSGIGLGLAVRLASDASRRFKGTARALGGSPGGREDPPPSLGARSRLVY
ATMRNLAKKERLLECVRGCHASTLEILQLDVTDPLSLAAAAQQVQEQRVDVLVCNAGVGL
MGPLETCSFQAMKTIFDVNVFGTIGTIQAFLPGMKRRKAGKIIISSSVGALQGIPFNAVY
CASKFAVEGLCESLAVILQQFNVHVTLIECGPVNTSFLANLQRTDAEGSALQGLDPQTRA
LYSQYLQHCQSLFRDVAQDTEEVLQVFLEAICAPCPPLRSFTTQFFMPLTRLKLTSPDGS
EYVRAMHKFVFSAGEAQGDQA
>A0A812C6W3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sepia pharaonis|TrEMBL
MVLSSSVSFLCISIEVCQVPHLPVHKKAVIITGCDRGFGHALAIKLDQMGFKVFAGCLFN
KGDGAEALKRICSDQLHVLQLDVRDPEQVDGAYNAVEEKLNDYELWGLVNNAGICFIGNS
EMISRNDSLRIMDVNFRGPYLMCSKFLPLLRRSQGIKIIPSGYKTGIIAYDKAKMAEKWW
AEAPDIVKEDFGKSSFLIKSKATDSDEMLSTDISPVINAMIDGLLSTNPKPIYYKGFLAR
SLPFLYYHLPSPLREPVIGIFTDWFDFQPSCLQDVD
>Q5LJT0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MERWHNCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRLEQLREELPQDRRSRLRI
MQCDVSDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVV
YCTQRAFESMRQRQSKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQ
EMRDFKTKVKVTVSTCLMNALQTNQEIIIHNRSFKASQNLVLLNRNISTYM
>Q9VU92|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MERWCNKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGLSLEQQSRLHA
IKCDITQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIETNIMGT
VYCVRESFRSMKRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQ
EFQRHKTAVRVSTVSPGIVDTVILPEQIQGIIKQHMPMLRSDDVADAVLWAIGTPPNVQV
HNITIKPQGEKF
>A0A3Q1H748|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Anabas testudineus|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPGKTYKVYATMRNLDKKERLLDCVKGLHKDTLDI
LQMDVTDRQSILDVRDRIAEKRVDILVCNAGVGLMGPLEVQSLDSMRQILEVNLLGTIQT
IQAFLPEMKAQGQGRILVTGSTGGLHGLPFNEVYCASKFAIEGACESLAVLLLHFNIHVS
LIECGPVNTDFLVNLQKVELGDLSLQQVDTQTLSLYEKFLQHCGSIFQNAAQDTEDIVKV
YLDAIKSPSPAFRYFTGGVVPPLTQMKITEPDGSQCIRAMSELIFSVEEKQ
>A0QWY9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)|TrEMBL
MSTPANSTPDTPSTVVVTGAGSGIGRAIATTLAERGWRVVATDVDVAAADETASSLSGSG
HESARLDVTDPAQASALADDVADRIGLGAWVSNAGISAMAHFVDISAEQLDRSLDVNLKG
VFFCGQAAARAMIRTGVRGTIVNTASMAAKQGRVPFLADYVASKFGVLGLTQAMAFELAA
HGITVNSVCPGFVATPMQTRELEWEAKLSGSTPDGVRQSWIDATPLGRLQTPDDVARAVA
FLVSEDARFITGEALSVNGGAYMD
>A0A2K5ZK21|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mandrillus leucophaeus|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARARGCPLGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEAVGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREEAQNPEEVTEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVAAMHRHVFGDDPAEAEAGAGTGG
GAGPSGVGDPELGDPPAAPQ
>M4A3U5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xiphophorus maculatus|TrEMBL
MEKKVVLITGCSSGIGLSLAVRLASDTSKVFKYATMRNLAKKERLLDCVKGLHQDTLEIL
QMDVTDRQSILTARDKVVEKRVDILCNAGVGLMGPLEVQSLDSMRHVLEVNLLGTIQTMQ
VFLSGMKAQGQGRILVTGSTGGLHLPFNEVYCASKFAIEGACESLAVLLQHFNILSLIEC
GPVNSDFLINLQKAELGDSSLQQVDGRTLSLYEKYLQHCSTVFQNAAQDTEDIVFLDAIH
SASPAFRYFTNSVMPPLTKLKVTEPDGMEYIKAMSKII
>A0A653VKQ5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Massilia sp. 9I|TrEMBL
MNNKKRIVVIGATSAIAEHCARLWLRDGSVDLTLVGRDLQRIDRVATDLRVRSPQSEIRT
VQAGFLDPAEVAAAVDGIVQAGPVDIVLIAHGSLPDQAQCQDALAACAEALEVNGLSPVL
YAEAFAKHMAQANHGAIALIGSVAGDRGRKSNYVYGAAKGLVTRYAQGLQHRFAGSGVKI
VLVKPGPTDTPMTAHLKSQGAKLAPVEGVARQIVDGIAAGKPVIYAPGKWWLIMMIIRHL
PAFVFNKMNI
>A0A378LS01|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella wadsworthii|TrEMBL
MKVAVITGAANGIGLALSQAHLERSHTVVMVDKDSMKLNQEVEQLLVQYPEKVMGIPCDV
TLPNDLAQMAHLVMSKLGRIDWIYNNAGIMGQLGPIWDVAPENIQQVMDVNLFGMIYSIQ
AFLPLLFQQTFRSHIINIASLYALCNGSQTASYAISKHAVLALSESLHFDLTRTKRPVDV
SIVFPSFTDTALLANQSDSGDPFHEALKSLLSHSRPAADVANYIVQEVEQKKFYIFPDKE
VKGYCEERTKAMILEEEPHITNIEKLMGALIKRQESRHKTI
>A0A2X2PHJ3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia cepacia|TrEMBL
MVVLKSIDVRDAEAMQVWLDCFDDEHPIDLLIANAGVASTLANSGDWEGRERTVRIVDTN
FYGVIHAVLPVIDRMKARRRGHIAMVASLAALRGMAISPAYCASKSAIKAYADSVRPLLR
RDGIRIAVVLPGFVKTAMSDVFPGDKLFMWSADQAASYIRRKLGVGRAEIAFPGLLAFGM
RLLPLLPITLADAILGRLSYLPSEEDPS
>A0A2X2PDR1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia cepacia|TrEMBL
MKEVILVTGASSGFGLLTAQALARAGHTVYASMRESSGRNAPRVAAIAAYAQAHGVDLRT
VELDVGDDASVAAAIDRVIADNGRLDVIVHNAGHMVFGPAEAFTPEQIAQLYDINVVSTQ
RVNRAALPHLRRQGRGLLVWVSSSSARGGTPPFLAPYFAAKAAMDSLAVSYAAELARWGI
ETSIVVPGAFTQGTNHFAHAGKPADSAVQAAYDDGPYAGVAGQALQGLAALEPADADAGT
VATAIADIVAAPAGKRPYRVFVDPSQDGAEEVFRVGDRVRREMFRNIGLADLLAARVGS
>A0A087DKM8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bifidobacterium stercoris JCM 15918|TrEMBL
MGYALITGASGGIGRELAALFAADGHDLAITARSQERLDMIKTKLEQRFGVHVVTFAIDL
SEANAPKKLHDFTTSQGIAVDHLVNNAGFADWTDFLDADWNRQNEMMQLNMHALAELTYR
YGRDMRANGHGRILNISSVASMMAGPYMAMYFASKAFVRSLSEAVAHELRGTGVTVTCVC
PGPTTTGFQKAANMSGRNFFTMTKPATARQLATYAYRRMMRGSTLAYHGPLTKAGALAER
VLPRALTRRIAAFMNGGKPHTLKV
>A0A2G9HAJ3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Handroanthus impetiginosus|TrEMBL
MMELIHMFLNIAAPPFTFFSLMLFLPPFQIFKFFLSVLGTLFCEDIAGKVVVITGASSGI
GESLAYEYAKRGACLVLAARREKSLHAVAERARDFGSPDVMVVKADVSKVQDCRRIVDQT
MNHFGRLDHLVNNAGIMSVAMLEEVDDVTDFRAIMDINFWGSVYMTRFAAPYLRNSRGRV
VAVSSSASWLPAPRMSFYNASKAAIAQFFETLRVEFGPDIGVTIVTPGFIESELTQGKFL
NNAGRLVVDQDMRDVQVNIIPVQRVESCAKAIVRSALRGERYVTEPAWFKVTYFWKLFAP
EVLEWIYRILYITRPGDPSSEAFGRKIMDYTGVKGVLYPESVQVPEPKRD
>A0A061ILV4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cricetulus griseus|TrEMBL
MASQLRLRSALALVTGAGSGIGRAISVRLAQEGAAVAACDLDGAAAQDTVRLLGGPGSEG
GAPRGKHAAFQADVSQAAAARRLLEQVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDR
VIAVNLKGTFLVTQAAAQALVSSGCRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQT
AARELGRHGIRCNSVLPGFIATPMTQKMPEKVKDKVTAMIPLGHMGDPEDVADAVAFLAS
EDSGYITGATVEVTGGLFM
>Q9VAH3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MSGSQLLRALRRSLGLGRQQLKVDSRHVVLITGCDSGLGHSMAVYCHESLHMTVISCCHN
IKSEGAKLLQGLASAKDGLSRMHTLELDLLEPDSIRLVHRQLRDILAKDPSYRLTALINN
AGVMCFGEFEWQLTEQIEAQINCNLLGTMRLTHELLPLLRQQQGRIINVTSHCGLQALPA
LGPYAASKAALRFWTDSLRVELQQYGMEVVNFIPGSFVLDSNIAARQQQHAQKMREAFSA
EQHALYDTYFEAFNGYLKVLSGFKPPNRLRNESLLAKFKDALTSSQPLALYIEEPRRYRL
YRWLFTLCPTPLVDWLTVRFCAMPTYESTNRQEKI
>C1LHA7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Schistosoma japonicum|TrEMBL
MLISRNPQKLATVANEIERKFNVETRTVTADFTNIDVYHKIQEAVNQLSSIACLVNNVGM
GVPKLDYYATTDYVTLNFIKNIVCCNTLPVASITHLILPKMLKQQTSGFAIINIGSHSAY
RPFPFLSLYSATKAFVNQLSRSISHENYGKQIIIQTVCPMFVSTAMNGYAKRSLFVPNAQ
VYAKSALDMLGVEEETFGYFGHAIKAYLTGFLPNLIWRHYMLFMKSWFDKQKRQ
>A0A061I758|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cricetulus griseus|TrEMBL
EGYLGCFQFLAITNNAAMNIAEQMSLYECASFGYMPKSGIAGSGADSGFGHALVKHLDKL
GFTVFAGVLDAKGSGAEELRKTCSDRLSVLQMDVTKLEQIEDAHSKVMEKTQDKGLWALV
NNAGIFHFPIDGELIPMTSYRKCMAVNFFGAVEVTKVFLPLLRKSKGRLVNVSSMGAKVP
IQLVAAYCSTKAALTMFSSIIRQELCKWGVKVAIIQPGGFQTNLSGTPEMWSKMEKEILD
HLSQETQDDYGQDYIHTQNFLQTMRERSFPDISPVIGDIQHAISARNPSSFYFPGRLTYL
WICFISYFPTSLVDYILQKCFAPKHMPRALRASS
>A0A2G8Y217|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii COUG|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALMRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKAMAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>A0A086QQV3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii MAS|TrEMBL
MESLAWRLCVYTLTWLAILGDADDLLQASRYKRDGSFLVPPHIWHVETAACRWMIHQRPN
VFRRLEADLRTESAFVGANHSQSWGDVLDACWSSSSFVSRALCLGVASFRGAAFALSAFH
SWREREKAQERKLAVLVTGSSSGIGLQVTRLLLALDFYVIGTRLHSEDPWRVFEEICGGS
SRLLLLPMDVTNAEDVARAVEATKKFLRENDVSGLYALVNCAGIWNWNFIQTQSPQETEK
SLKTWRELFDVNLLGAVRVMHAFLPLMQARAVFVGSILGRMSSPGQTAYCASKAAVRLLA
EGARSDARDAGVNVVLVAFLAEVRVAPAQHVKSSTCVFAKETLTLCHPGRRRRTRGQVSP
RHPRGCFYRPVQSSAGARLSARANRERNCRLHSLCSDAAHCSLCWMGYVRMETA
>G4CXX9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cutibacterium avidum ATCC 25577|TrEMBL
MTEKDATRDERPWALVSGASGGLGQAFSRHLASCGANLVLTGRRQDVLDDLATKLTTRYG
IRTIVRPCDIASASERLTLVEDIAGRGIIIDTLVNNAGFGAAGRIAETDPVRQTSQVEVN
CEAVVHLCGLLLPGMIAAKQGSIINVASTAAFQPIPQFATYAASKSFVLSFTKALWAETN
GTGVRVTAVCPGPTETGFFDVAGVPRMGAGTRRQPDDVVRTAFDALARHRPYAIDGFINR
AVARLAPHLPPRLVMTEAEKYLKI
>A0A653V709|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pseudomonas sp. 8BK|TrEMBL
MSTHNEKGTALITGASSGIGATYAERLAQRGYDLLLVARDLPRLQALSARLTEQYGVKVE
ALKAGLTDKADLHAVTQRLRTDKAISTLVNNAGMAMGGQLAEADLDTVDRMILLNVVSLT
HLSTAAAAKFTAAGRGAIINIASVVALAPEMFNAVYSATKAYVLSLTQTLNGEVKAQGVQ
VQAVLPGITRTEIWERSGMDDSALPASMIMEVGEMVDAALAGFDQGELITIPSLPDAADW
QAFTDARGKLAPNLSHSSAAARYK
>A0A087A167|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bifidobacterium callitrichos DSM 23973|TrEMBL
MAYAVVTGASNGIGRELAALLARDGHDLVVVARSRAGLDRVRAVLERDYGIRVKTFAADL
SEDGAPERLHEFTRSRGLQVDTLVNNAGFSEWTTYLDGDWDRQRRMMRLNMEALATLTRL
YGRDMRDAGDGRILNISSVASMMAGPYMAMYFASKAFVRSLSEAVAYELRGTGVTVTCVC
PGPTSTGFAKAAHMSGRNFFTMTRPATARGLALYAYRRMNAGDVLAYHGAFTKAGAFAER
ALPRALTRRIAAFMNGGRPKI
>A0A073CNJ3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Planktothrix agardhii NIVA-CYA 126/8|TrEMBL
MRLLVVCPGPTESNFFVAAEFPQTLSGVGQNYATAEEVVQDTLTALEKDFSTLVTGGFSN
QFIVNLPRFFPRDTIVSLVEKQFKPKK
>A0A086Z2A4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bifidobacterium actinocoloniiforme DSM 22766|TrEMBL
MNKQTWLITGVNSGFGLELTRQLLAAGHKAVGTIRRESPAVAELKAQYPDTLETPNLDVT
DVEAVHRVVGAAFERQGRVDVVVNNAGYGLFGAAEELSDQQVEHIIATNLLGSIQVIRTA
LPYLRRQGAGIIVQISSYGGQVAYPGNSMYHATKFGIEGFVESVAQEVKPFGIRTMIVEP
GGARTEFRYGSAQVAQLMPEYDGPTHAFLKMLDPANGLAPGDPAEMAARIIECAADPETP
PACRIRLRGPAQRHPAA
>A0A3S4HXE9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella sainthelensi|TrEMBL
MSKHAVLALSESLYFDLERMKKPVNISVAFPSFTDTALLSHSEHTHSQFQEILKSLLSHS
RPAMDIAEHIVRGSRAKEILYFS
>A0A086KG23|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALVRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKAMAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>A0A8C6DV15|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Moschus moschiferus|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSQSFKVYATLRDLASQGPLLEAAQARGCPPGSL
ETLQLDVRDADSIAAAQARVTEGRVDVLVCNAGRGLVGPLEAHKEGSVDAVLDVNLTGTV
RMLQAFLPDMKRRRSGRILVTGSIGGLMALPFNAVYCASKFALEGLCESLAILLQPFGVH
VSVIECGPVHTPFPEKAEGGLGGVLDRADAETRDLFYRYLRHCERVIREAGQDPEEVVEV
FLQALRAPRPALRYFTTERFLPLVQLRFSDPSGSSYVAAAHQSAFHDKAAEGSDGAGAEA
EAGKLGASELRAPLAPQ
>A0A1S7U8X7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Agrobacterium salinitolerans str. Hayward 0363|TrEMBL
MQEVILVTGASSGFGLLSAQALAKAGHTVYASMRETTGRNAPQVASVAAWAKEHNAHLRT
VELDVSDDASVEAGVAKVIADNGRLDVVVHNAGHMVFGPAEAFTPQQYAQLYDINVLSTQ
RVNRAALPQLREQGRGLLVWVSSSSARGGTPPFLAPYFAAKAAMDSLAVSYASEVARFGI
ETSIVVPGAFTKGTNHFAHSGKPADQALADAYASGPYAGVADQALKGLAALEPADADAGA
VAMAIADIVNAPFGKRPYRVFIDPSQDGAEEVFRVGDRIRREMFQAIGLKDLLAPRINT
>B5MBT7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sus scrofa|TrEMBL
NAGIMPNPQLNIKALFCSLFSRKAIHVFSTAEGLLTQNDKITADG
>F0SK61|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MKWKVERKCAIITGAASGIGRALALELTRRNVHVCLVDRDADKLQATATACRQFDVLVED
FAVDLTEPDAPARIYQHVLSTMGGLDVLINNAGVGYYGSFEPMSAEQIETLLSVNLNSAL
QLTNTLLPLLLQNERAHVQNVSSIYAMFPTRRSAAYHASKYGMLGFSLALRAEYARYGLG
VSCLCPGFVRTELFDNMLLPEHQHRPAPPNWLTTSPERAAKRAVRAMQRNQRIATVTWLD
WAIHRCSWLATPLLDLLNGLERRRPHEFAKRQLKQIPMPLDKVIEKEGFPPAGQHASNGE
AGLATSPISPTNTTSDVSPDRDRE
>A0A378IYH5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella donaldsonii|TrEMBL
MEKTALVTGATHGIGLALSKNLLSNGWLVFGTGRDLASLETTQALFPNFIPIQADFTKND
DIQNVASTIKKTGLPLSLSVQNAGMKSPPRPLEQYTCGSIDEELMVNLLAPMKLTALLST
QMPAESRILYLTSRAATLKLKEGSTYCASKAALDEVAAIVRKELEERNIGVSTVIPGEVD
THIQKILRETTSFHLHQKFEEIYQKGQLINPTVCATFLKWLLCDLSFAEFKQSKMPVSIY
DKWHHQFWLTEANQLPAFPF
>A0A1N6MVV1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xenorhabdus innexi|TrEMBL
MLKESNKPDGFKGKRVVVTGGGRDFGQAISVWLAREGAHVDLCARQLKSAEITREIIQNE
GGSARSYQCNIGDVQSVRSFTEQLLQDSKPIDILILSAAQWLEGGLSENDSDEDIISTMN
SGATGSMLLTKMLLPSLRQSQGADIIAMVSICGVPNFTRSVAHPVFFAAKHAMSGFCNTI
SHQLSKDNIRVTGIYPPDFETNGFDTDLSDHTTVGKQMLNGRSVWESIRFVLTQPRSCHV
SAIYFQRPTFEDMKQL
>A0A3B4DEH5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pygocentrus nattereri|TrEMBL
MEQKVVLITGCSSGIGLSLAVHLASDLSKAYKVYATMRNLDKKQHLLESVTGLHRDTLAI
LQMDITDQHSILAAQRSITEGRVDILVCNAGVGLMGPLEVQSEDTMRGILEVNLLGTIRT
IQTFLPDMKRRKHGRILVTGSMGGLQGLPFNEVYCASKFAVEGVCESLAILLQHFNIHVS
LIECGPVNTNFLRNLTKTELSDVSVEVDADTRSLYEMYLHHCQKMFQNAAQDTDDIVQVF
LEVIQSPCPLFRYYTNSALLPLSSLKLTALDGSQYIRAMSKLIFSVENADTPK
>A0A086Q1Y6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii VAND|TrEMBL
MESLARRLCVYTLTWLAILGDADDLLQASRYKRDGSFLVPPHIWHVETAACRWMIHQRPN
VFRRLEADLRTESAFVGANHSLSWGDVLDACWSSSSFVSRALCLGIASFRGAAFALSAFN
SWREREKAQERKLAVLVTGSSSGIGLQVTRLLLALDFYVIGTRLHSEDPRRVFDEICGGN
SRLLLLPMDVTNAEDVARAVEATKKFLKENDVSGLYALVNCAGIWNWNFIQTQSPQ
>A0A6I8N900|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ornithorhynchus anatinus|TrEMBL
MARTVVLITGCSSGIGLHLALRLAAHPSRSFKVYAALRDPAAQGPLWEGARARGCPPGSL
QTLPLDVTDPGSVAAAKAAVSEGRVDVLVCNAGRGLVGPLEAQTTGAARQVLDVNVLGSV
HLLQAFLPDMKRRRAGRVLVTGSIGGLQGIPFNAVYCASQFALEGLCESLAVLLLPFDVH
LSLIERGGPGGVLGDADPETRALFARYLQHSERLFREAAQEPEEVVEVFLAALRAPRPAL
RYYSTERFLPLARQRLEDPSGSRYVAAMHRFVFEEEPGAGGLSPLEP
>A0A452FYT8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Capra hircus|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASHPSQSFKVYATLRDLASQGPLLEAAQSRGCPPGSL
ETLQLDVRDADSIAAAQARVTEGRVDVLVCNAGRGLVGPLEAHKEGSVDAVLDVNLTGTV
RMLQAFLPDMKRRRSGRILVTGSIGGLMALPFNAVYCASKFALEGLCESLSILLQPFGVH
VSLIECGPVHTPFPEKVEGGLGGMLDRADAETRDLFYRYCRHCERVIREAGQDPEEVVEV
FLQALRARRPALRYFTTERFLPLVQLRFSDPSGSSYVAAAHKSAFHDVAAEGSDGNGAEA
EAGKLRASELRAPLAPQ
>B2X0A4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sus scrofa|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSQSFKVYATLRDLTAQGPLLEAAQARGCPPGSL
ETLQLDVRDADSIADARAHVTEGRVDVLVCNAGRGLVGPLEAHREGAVDSVLDVNLAGTV
RMMQAFLPDMKRRRSGRILVTGSLGGLIGLPFNAVYCASKFAIEGLCESLAVVLQSFGVH
VSVIECGPVRTAFPEKLEDGLGGILDRADAETRDLFSRYLSHFEQTFLEAAQDPEEVVEV
FLQALRAPRPALRYFTTEHFHPLIKLRFSDPSSSSYVAAEHQRVFGDQATEGFEGTDCGE
AEAGAGDLGPSELGAPLATPQ
>A0A7X6B104|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Streptomyces malaysiensis|TrEMBL
MSVVLITGAATGIGNLTAKALARAGHTVYASMRSVKGSNREHARELLDIAEKENQDLRVV
ELDVTSQEAADAAVQRILEETGQLDVVVQNAGHLYVGYLEAFTPEDLAHLFDTNVLGAHR
VNRAALPHMRQRRAGTLIWVGSTIPITTPPFLGPYTASKAAMDSLAVSYAYELNAFGIES
TIVMPGAFTQGTQHFPDASQAGDAARAAEYAELDPLVQRNNEAHDQLFPHGAENAHPSAV
ADEIVRVLALPRGTKPLRTVVDFTEAGVEKANAVVQSTREAFVQRMGFGELLQVKR
>A0A8C7KTW0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Oncorhynchus kisutch|TrEMBL
MEQIVVLITGCSSGIGLSLAVRLASDPAKMYKVYATMRNLAKKERLLDCVKGLHKDTLDI
LQMDITDQQSILDARDRVREKRVNILVCNAGVGLMGPLEAQSLATMRRILEVNLLGTIST
IQAFLPGMKAQGHGRVLVTGSIGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLDNLQRAEPGDSSLQQVDAHTRSLYDTYLQHCGMVFQNAAQDTEDIVKV
FLDAIQSSNPAFRYYTNNALIPLSSPKISALDGSQYIRNMSKIIFSTNGKGEQK
>B9RMR0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ricinus communis|TrEMBL
MEIQDSILIAVSGLGFVILIKQMFIFLKGVRVMFLRPPKNLKKQYGSWAIITGSTDGIGK
ALAFELASEGLNLVLVGRNPSKLEATSNEIQARNGENKQVQIKTILLDLARSNREEISRE
IGDAIQGLDVGVLINSAGVAYYPTYFHEVGQELIDSVIKVNAEAATWVNRAVIPVMMRKK
KGAIVNIGSASSAVFPSYPLVTVYASTKAYLEMLSRCINLEYKHHGIDSQCQIPLFVATK
MTRLESSFLVSSTEMYAKESIRRIGYEQLCAPFWMHSLQWSILQALPDSVVDWLLLRIHN
FLRKKGLENDPLLNQEICVYDILCLALFGD
>G4HTJ2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mycolicibacterium rhodesiae JS60|TrEMBL
MADGFAGKRVLITGAASGIGRSTALRLARDGAELYLTDVNADGLEQTVADARALGAVVGE
HRALDIADYDAVARFAADVHTHHPAMDIVMNIAGISAWGTVEQLTHRQWRSMIDVNLMGP
IHVIETFLPPMVAAGRGGQLVNVSSAAGLVALPWHAAYSASKYGLRGLSEVLRFDLARHD
IGVSLVVPGAVDTPLVKTVQIAGVDRDHPGVQRWIARFSGHAVTPEKVADAILAGITKNR
FLIYTSPDIRALYAFKRLAWWPYSVAMTRVNVFFTRALRPRSATFSPPS
>V5B3C6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
MESLARRLCVYTLTWLAILGDADDLFQASRYKRDGSFLVPPHIWHVETAACRWMIHQRPN
VFRRLEADLRTESAFVGANHSLSWGDVLDACWSSSSFVSRALCLGIASFRGAAFALSAFN
SWREREKAQERKLAVLVTGSSSGIGLQVTRLLLALDFYVIGTRLHSEDPRCVFEEICRGN
SRLLLLPMDVTNAEDVARAVEATKKFLRENDVSGLYALVNCAGIWNWNFIQTQSPQETEK
SLKTWRELFDVNLLGAVRVMHAFLPLMQARAVFVGSILGRMSSPGQTAYCASKAAVRLLA
EGARSDARDAGVNVVLVAFLAEVRVAPAQHVKSSTCVFAKETLTLCHPGRRRRTRGQLSP
RHPRGCFYRPVQSSAGARLSSRANRERNCRLHSLCSDAAHCSLCWMGYVRMETA
>H0TVK1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bradyrhizobium sp. STM 3843|TrEMBL
MHSKQEQVKPVAEGVWVVDAGRIHAAGLPLPVRMTVIRLKSSDLLLHSPTQYSDDLRREL
ERLGPIKYLVAPNIAHWMFLPEWQAALPIAKLFAAPGLAERAQVRRSGLRIDHELGERSP
DEWAEDIELVLVSTLLFSEVELFHKPSRTLVLTDLVQNLAPEGLSPLSRAAASLLGITAP
NGKAPAYLRLLLRLGGRPVETAVSRLIELAPERVIFAHGRWFESGGTEQLRRSLSWLRRS
AGARVALPATRELSAVRVVVTGASSGIGRATALALARRGASVALAARRADVLNDVAAECD
ALGGHALAVPTDVTDAQAVQRLADAAEKAFGGIDVWINNAGTGVFGAFGEADIALHRRTI
EVNLLGTMNGAYAVLPIFQRQRRGILINNISLGGWAPTPFAAAYTASKFGLRGFSASLRQ
ELTAHPDIHVCSVFPAMVDTPGFVHGANMSGRNLDPGPLLYRPDDVAETFLQLIRSPRDE
VAVGWPARLGQVSYALARGPTERLMGAGFRFLLARARPAPRSEGALLAPVPAGKSASGGW
LARKRLPPADQLSKIGLALGILVIAFTGLAMARGPSSRSHRRHRRA
>A0A5B7B5I2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Davidia involucrata|TrEMBL
MELCFMDQLKSQPLWLLLLLGLGSVSVLKCSLALLKWVYVNFLRPAKNLKKYGSWALVTG
PTDGIGKGFAFQFARKGLNLVLVGRNPDKLKEVSESIRAKYGKTQIKTVVVDFSGDLSQG
VERIREAIEGLDVGVLINNVGVSYPYARFFHEVDEKLLADLIKINVEGTTTVTHAVLPGM
LKRKKGAIVNIGSGAAIVIPSDPLYAVYAATKAYIDQFSRSLYVEYKKSGIDVQCQVPLY
VATKMASIKRSSFFVPSTDGYARAAMHWIGYEPRCTPYWPHSLLWSLAHLLPESAVDAWR
LRFCLAIRKKGQLKDSRKKE
>A0A2K5LEF1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cercocebus atys|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARARGCPLGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEAVGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREEAQNPEEVTEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVAAMHRHVFGDDPAEAEAGAGTGG
GAGPSGVGDPELGDPPAAPQ
>A0A7M4DXW6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Crocodylus porosus|TrEMBL
MEKTVVLITGCSSGIGLGLAVRLASDSSQRFKGNRQPRGAFGRCPCSWHPYTSPGLGNIF
ATMRDLAKKERLLECVRGCHRDTLEILQLDVTNPASLASAIQRVPEQRVDVLVCNAGVGL
MGPLETCSQEAIKAVFDVNLFGTINTIQAFLPGMKCRKAGKIIITSSVGALQGVPFNAVY
CASKFAVEGLCESLAIVLQEFNIYITLIECGPVNTSFLSNMQSMDPEGHELQGLDPKTYA
LYRQYSQHCQSLFQDAAQDTDEVLQVFLDAICTPNPPLRCFTTQFFMPLTRLKLLSPDGS
EYVQAMHKFVFSTSNSGQGPAGSGRLYLGGGPGAPLLCVPGMRKDTEQGW
>A0A812B7C3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sepia pharaonis|TrEMBL
MGDVLSAVFYLHQAHQLRHFKRHHRTVQTALLSSSDNHGEARPICLILSLSQELDLTNCY
LSIYLSIYLSIYLFIYLSICLYSRKCICWSLLIKLITLSIIYWTLTYSNPQEPNCYGTTI
FITTLVLVHQSLGIPHLPVLNKAVIISGCDRGFGHALAVRLDQMGFKVFAGCLFKGGEGA
EALKAKCSKRLHILQLDVTDPEQVDSAFITVKENLENYDLWGLVNNAGICYIGNSEMIPR
EDSLKIMDVNFRGPYLLTTKFLPLLRRNQGRIVNVSSNAGLAPVALMGLYCCSKSALFMY
TEVLRTENERWGVKVSAVIPSGYKTGIIAYDKEKMAEKWWAQAPKVVQEDFGKAAFVIKS
KAGDSDDMLSKDLSPVINAMVDGLLSANPKQIYYKGFLARSLPFLYFHLPRVLRGPVMGV
LADWFEFHPACLEDDQS
>A0A098GA61|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella fallonii LLAP-10|TrEMBL
MSKILITGSTDGLGKMAAQLLIEQGHKVVLHARNIQRAAEVANALPGAQKVVIGDLSRIM
EIKAVAEQANQLGHFDAIIHNAAIGYREPHRVETKDGLCHVFAINTLAPYILTALIDKPK
RLVYLSSGMHYNADTSLYDLNWMRREWNGAEAYAETKFHNTLLAFAVARLCPEVLSNAVE
PGWVATKMGGPEAPDDLDAAPRTQIWLATSNEPEALVSGQYFYHLQPRLPNPDARDIRKQ
EHFLEYCAEISGVYLNNVRRTT
>W8YHT3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Paenibacillus sp. P22|TrEMBL
MSKAAAITGASSGIGLASALKLASEGVRVYAGTRNLERDSMRHAGTANLTFLEMEVTDPA
SLERAFRTIEEEQGRLDLLFCNAGFGCLRALGQAEMADIERVFDTNVYGVMNTIRAALPL
LRRSGQGYIMTTSSVGGLVGQPFNEIYCASKFAVEGLMESLATYYKPAFNIDITLLEPGA
IATEFTGTVMNHLQQTGGILEDEYKPILTRYMDNFAARTSVPQTSESVAEVVWSLVQAAD
KPLRIRTSEAAEAFARFKTEQDPTGLIGLKNTRRLHLNIDEEQ
>A0A8C9MUT8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Serinus canaria|TrEMBL
MGWPRRAALPGMERTTVLITGCSSGIGLGLAARLAADPARRFKVYATMRDLAKGEWLLER
LGGCCPDTLELLQLDVTDPCSLAAAAQRVQGQQLDVLVCNAGVGLMGPLETCSEQAMKTL
FDVNVFGAVRTIQAFLPAMKSRRAGRIIVSSSIGGLQGLPFNAVYCATKFALEGLCESLA
IVLHPFNIHLTLVECGPVHTSFLDNLQRPDPEGSEMRDLDAETQGLYRRYLGHCQSIFRD
TAQEVEEVLPLFLEAIGSPCPPLRCASTQLLAPLWRLRLSSPDGSAYVRAMHDFVFGDSE
AGEDQP
>A0A087D277|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bifidobacterium ruminantium|TrEMBL
MGYALITGASGGIGRELAALFAADGHDLVITARSQERLDMVKTKLEQRFGVHVVTFAIDL
SEANAPKKLHDFTTSQGIAVDHLVNNAGFADWTDFLDADWNRQNEMMQLNMHALAELTYR
YGRDMRANGHGRILNISSVASMMAGPYMAMYFASKAFVRSLSEAVAHELRGTGVTVTCVC
PGPTTTGFQKAANMSGRNFFTMTKPATARQLATYAYRRMMRGSTLAYHGPLTKAGALAER
VLPRALTRRIAAFMNGGKPHTLKV
>A0A3Q3RFP8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mastacembelus armatus|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDSDKAYKVYATMRNLAKKERLVECVKDLHKDTLDV
LQMDVTDQQSILNVRDRVVEKRVDILVCNAGVGLMGPLEVQSSESLRHILEVNVVGTIRT
IQAFLPEMKAQRQGHILVTGSIGGLHGLPFNEVYCASKFAIEGACESLAILLQHFNIHMS
LIECGPVNTDFLVNLQKAELGDTSLQQVDTETLSLYEKYLQHCGSVFQNAAQDTEDIVKV
FLEAIQSPSPALRYFTSGVVPPLTQLKVTEPDGSRFIHTMSKLIFSSDDQ
>K6Y3X9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Paraglaciecola arctica BSs20135|TrEMBL
MACILITGCGSGLGASLATRLANEGHEVIATVRSLTHGKIQNSIAATFNSPKFIQMDVTN
TNEVQTVFDEFEKHDKKLDVVILNAASYSMGTIESTNYEQSKQCFDVNYWGGVNVIRAVL
PIMRRQLSGKIIGIGSISSAIALPCDGYYSASKAAMERTLESLRHEVAPFGLHVSNIAPA
SFGSNLFQSLPDELLESNPYSPLLKEWLANIKQNTNPNGIGRTEVEDIILSVISSNEPDF
IYPAGAMALKVLSSLKTMTAEERTHAISTWSDTQWWSKANFKE
>B6R2W6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pseudovibrio sp. JE062|TrEMBL
MMQPRFAGETALITGAGSGIGRATAIRLAEEGAAVALVDRNEDGLDETASLLPEGCRARI
YVVDVADEEAVETCVEAVENTFGGISILCNNAGVICEGSWGGSHEDFGDWLKVYEVNVLG
AMLFTKYTREQLKASGRGSIVNTASVAGIRAGAGGNAYSASKAALINFTMTSACDFGEHG
VRVNAVCPGLIETGMTKPVFDHARSVGKEDKLGSRAELRRHGDPAEVAATIAFLASKDAS
FITGQALAVDGGNTSSLNMPGMKI
>A0A2I3GI98|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Nomascus leucogenys|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHRKVFGDCPANAEAGAGASG
VGDPELGDPPAAPQ
>G8TRF2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Niastella koreensis (strain DSM 17620 / KACC 11465 / NBRC 106392 / GR20-10)|TrEMBL
MAKTVLVTGASSGIGKATAIYLAQNGYQVYGAARRLNRLQELNTFGIIPISLDVTKEESI
EACVASIGSVDILINSAGLGSYGALEDVPIPEAKNQMEINLFGVARLIQLVLPQMRKNRY
GKIVNISSVGGKMGLPMGSWYHASKFALEGMSDCLRNEVRQFGIDVIVIEPGGTQSEMMA
IGAENMQRVSKKSVYSNLATGIQKMYANMEKNAAAPIVVARLIKKGIEAKHPKTRYIGGT
MAKPMLFMRKLLSDKLFDKMIMSQIK
>G6FAR5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Lactococcus lactis subsp. lactis CNCM I-1631|TrEMBL
MTLAVLPYMRKQKSGHILNTVSRGGLTTTENLSYYHATKFAMEGLFQTLRKEVEPLGIFV
TNIEPGSFRTDWAGRSKESAPDKFSDYEKAHKLLEHLNSYSGTQVGNPASAAKAFIKVSK
LENPPMHYLMGKDAYQLSKQVFEEALAEFEKYKEDAKHLDFGEEDYWK
>K9VHK6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Oscillatoria nigro-viridis PCC 7112|TrEMBL
MTNQTSSRVWLITGSSTGFGRTLAEAALAQGDRVIATARDVSKIQDLEQQYPQTGKAVCL
DVTDPATIQTAVRSGLAAFTRIDVLVNNAGYGLMGAIEEVSDQQIRDQLETNFFGLLNVT
RALIPIFKKQGVGHILNISSIGGRKTFPTMGLYHASKFAVEGLSESLAQELKPFGIKVTI
VEPGGFETDFSGRSLMTAKQMPEYNSLRAEVVKFAAEQPRGHVPTGVQAMLKVVELPDPP
LHLAIGPNALPTIVQKLFSDIEEYQRFEHIWQESTANAGVGFNFPSLTQQV
>F0RLM7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Deinococcus proteolyticus (strain ATCC 35074 / DSM 20540 / JCM 6276 / NBRC 101906 / NCIMB 13154 / VKM Ac-1939 / CCM 2703 / MRP)|TrEMBL
MRVSKRLLLAGAAAALAARRTLTPRYALSGKSVLITGGSRGLGLALAREFAARGARLTLV
ARTSSDLDTAAAELRGQGTEVATVTADLTKREEVERAVQAAMTAHGALDVVVHSAGMIQT
GPLQDMTEDDWREVMEINAFAALRLVRAAYPHLKAAGGRVLLVTSIGGKVAVPHLGPYSM
SKFAAVGLGAALRAELGLDGIGVTTVCPGLMQTGSPKHALVKGQHEKEYAWFATIDNLPL
VSMPAPAAARGMVDALVRGDAEAMIGVPAAVARYAQALAPQLVADAMALTNRFLPGPTGN
PQARRGADAESEVTRSNPIKRAAEQGFNQE
>L7EB54|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Microcystis aeruginosa TAIHU98|TrEMBL
MKTALITGASTGIGVVFARQLAQRQMELILVARSRDKLEQLAAELGEQYGVKVTVIVQDL
TVAGAGRLVYDTVNQKGINVDLLVNNAGFGDYGAFSEQDLARQLEMIQLNNLVLVELSHY
FLRPMLAGTGGAIINVASIAGFQPLPYLSVYAATKAFVLSFSESLWAENKDKGVEILALC
PGPTESNFFEVARFPSAFMGKNGRLDSAEVVVQEALTALANKRPNVVAGKFANKIIVNLP
RFLPRSWIVSLIEKQFKL
>I0K624|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Fibrella aestuarina BUZ 2|TrEMBL
MKKTVLITGTSSGIGRASVRYFAQQGWNVAATMRSPEKEANRGADSLGTLPNVQLFRLDV
QDTASIRQAIADARAAFGGIDVIINNAGYGAVGPFEAATPAQIQQQFDTNVFGVMNVIRE
ILPYFRERRGGSILTVTSMGGLITFPIYSIYHGTKWAVEGFTEALSFELKPFNIRVKNIE
PGAIKTDFYDRSQDVLTQPGLTDYDRYVAVTMANSQQAGADAPGPEVVAKTLFDAANDPS
DRLRYVSGNSQTRALLFMRRVLPLRWFHGLVKRVVEKGYQA
>A0A7U3ZL34|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Runella slithyformis (strain ATCC 29530 / DSM 19594 / LMG 11500 / NCIMB 11436 / LSU 4)|TrEMBL
MSKVILITGATTGIGRATAEYLTQSGHRVYGTGRKPFTEVVPFQTLQLDVNDEASVQAAV
SQLLQREGRLDVLINNAGLGIIGALEETPDEMIEQVFHTNVYGLLRMCRATLPAMRLQGE
GLIINVASIAGRMGLPFRGIYSASKAAVEILTETLNIELKPFGIRACSILPGDVRTNINA
ARLVAMPPVSSPYRSWVETMNAIVNEEVSKAEDPIYIARIIEAAINSSSPKIHYIAGPFL
QRFSLWLKRFLPSRFFEYLLRGNYGLK
>A0A8C5L5I1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Jaculus jaculus|TrEMBL
MDRTVVLITGCSSGIGLHLAVRLASDASQSFKVYATLRDVKAQGPLLEAARARGCPPESL
EILELDVRDTGSVATARARVTEGRVDVLVCNAGRGLMGPLEAHELDAVGSVLDVNVVGTV
RMLQAFLPDMKRRGSGRVLVTASMGGLMGLPFHAIYCASKFALEGLCESLAILLLPFGVH
VSLIECGPVQTAFHEKLEGGPGGSLERADAQTRRLFLNYQHHYQKILSEGQDPEEVTEVF
LTALRAQKPALRYFSTDRFMPLARLRLDDPSGSSYVAAMHQASFPDLQTQEVTNAEALST
VASNAFLCLQGCAVARVRIRVAYPLCWSAMGNLSGQIMLPQLYL
>K9PXJ5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Leptolyngbya sp. PCC 7376|TrEMBL
MANTVLITGSSSGIGKATAKYFQEKGWNVIATMRSPQKETELTELENVLVTRLDVTDSES
IESAIKAGLEKFGKIDALVNNAGYGAFGALEGFPIDKIRRQFDTNVIGLLETTQAVLPHF
RQQKSGTIVNVSSVGGKMTFPLFSLYHGTKFAVEGISESLHYELEPIGIKVKIIEPGAIA
TEFAGRSFDFVNDESLSEYQDITNKLLGAFETIGSQSSPASVVAEVIWTAVTDGTKTLRY
TAGEDAKVFMANRKALDDETFINGLKEQFGL
>C5P0G9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Coccidioides posadasii (strain C735)|TrEMBL
MAASVGRLHGKTAVVTGASSGIGRAIALRYAAEGAHVVCADIDSASKDPDDTRPTHEAIN
QEYPAGEGTSQRSIFVKTDVTSGTEVENLVRECVNAFGRLDIMVNNAGVANGPSNPPGPI
HKTPESSWDTIVGVNAKGVWLGCKYAITQMLNQDPHPSGDRGWVINMASVLGLVGSTGTS
PYCASKGAVVQMTKSIALDYGQDRIHVNGIAPGYIETPLVKPFLDPHSPDPRARALYAAI
GSKHPFAQRMGKPEEIAGSAVFLASDDASWITGHILPVEGGYLAQ
>A0A2U9CRD0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Scophthalmus maximus|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPNKTFKVYATMRNLAKKERLLESVKGLHKDTLDI
LQMDVTDRQSILDARDRVVEKRVDILVCNAGVGLMGPLELQSLDTMRQILEVNLFGTIQT
IQAFLPEMKAQGQGRILVTGSTGGLHGLPFNEVYCASKFAIEGACESLAVLLQHFNIHVS
LIECGPVNTDFLVNLQKVELGDTSLEQLDTHTLGLYEKYLQHCDSVFQNAAQDTEDIVKV
FLDAIQSPSPLFRYFTSGVVPPLTQLKITQPDGSQCIRSMSKIIFSSEEK
>B7QHV0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
LTDTTMSFCLPFAGQTAVVIGGGSGIGKSTCNALASEGALVVVADISLETARTTAQSLPE
ISQHLAIQVDVGSSQSVKALFETVGRECKVPPSIVVNCAGIMGARRYLTETPEDDFDNVV
RVNLKVINFLYI
>C1LHA6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Schistosoma japonicum|TrEMBL
MDWIYLISVIICLFLVKEFFNLLSIIFTYTIGKRLFSKRKLLKHAGEWAVVTGATDGIGK
VYAEELARDGLKIMLISRNPQKLATVANEIERKFNVETRTVTADFTNIDVYHKIQEAVNQ
LSSIACLVNNVGMGVPKLDYYATTDYVTLNFIKNIVCCNTLPVASMTHLILPKMLKQQTS
GFAIINIGSHSAYRPFPFLSLYSATKAFVNQLSRSISHENYGKQIIIQTVCPMFVSTAMN
GYAKRSLFVPNAQVYAQSALDMLGVEEETFGYFGHAIKAYLTGFLPNSIWRHYMLFMKSW
FDKQKRQ
>S7UMX7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii (strain ATCC 50853 / GT1)|TrEMBL
MESLAWRLCVYTLTWLAILGDADDLLQASRYKRDGSFLVPPHIWHVETAACRWMIHQRPN
VFRRLEADLRTESAFVGANHSQSWGDVLDACWSSSSFVSRALCLGIASFRGAAFALSAFH
SWREREKAQERKLAVLVTGSSSGIGLQVTRLLLALDFYVIGTRLHSEDPRRVFDEICGGS
SRLLLLPMDVTNAEDVARAVEATKKFLRENDVSGLYALVNCAGIWNWNFIQTQSPQETEK
SLKTWRELFDVNLLGAVRVMHAFLPLMQARAVFVGSILGRMSSPGQTAYCASKAAVRLLA
EGARSDARDAGVNVVLVAFLAEVRVAPAQHVKSSTCVFAKETLTLCHPGRRRRTRGQVSP
RHPRGCFYRPVQSSAGARLSSRANRERNCRLHSLCSDAAHCSLCWMGYVRMETA
>A0A653UJ46|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Arthrobacter sp. 9AX|TrEMBL
MTTAHPQHDLSGTTALITGASAGLGAEFARQLAEQGHNLVLVARDQARLEEAAAGLERRY
GITAEVLPADLTDDADVAAVVGRLSDPQQPVGILVNNAGIGLLHNFEDNPVPEEQKHLKL
HVETSMVLAHAALKGMLDRGEGRIINVASIAAFLPRGTYSAAKAWMVSFSRWANLAYGER
GVKVTAVCPGFVHTEFHERMGMDKSVAPSWTWLRPGRVVREGLADNARGKAVSIPTKRYK
LVAALARIAPAKLVAGPPRKPDEGSNGP
>A0A8C3ZJF5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Denticeps clupeoides|TrEMBL
MDLKVVLITGCSSGIGLSLAVHLASDPSKTYKVYASMRNMDKKQRLLECVSGHHKDTLVI
LQMDVTDQQSIHRAKDSITEGRVDILVCNAGIGLMGPLEAQSEDVMRGILEVNLLGTIRT
IQTFLPDMKRRKSGRLLVTGSMGGLHGLPFNELYCASKFAVEGVCESLAILLQHFSIHVS
LIECGPVNTDFLVNLQRVEPRDSSLVEVDDHTLHLYEMYLQHCSSVFQNAAQDTEDIVQV
YLEAIQSPRPFLRYYTNHGLLPISTPDGSQYITAMSKIIFSSTIPKVRF
>A0A0W0WFZ3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella maceachernii|TrEMBL
MTSLQDKTTWITGASSGIGEALVYEITRAGAKVILSARNEEALQRVRKNCVSPEKHSIIP
LDLENYRELKKKAEEVWDQHGPIDVLIHNGGISQRYLAADAELEMDEKIMKINFFGAIAL
THPILKKMLERNSGHLVVTSSILGLYGVQTRSAYSASKHALKGYFESLRNELVKTGVKVT
LVYPGYINTQISMHALVANGTVYGKADKAHMNAIPRENCARQMREAIEQDKPEVIIAGFK
EKLGLLASRLLPSLFRRLTPKLEI
>A0A378PGV1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella steigerwaltii|TrEMBL
MTNINNNKAALVTGASHGIGLELAKILLGDGWVVYGTGRDVSSLEDTKALYSRFVPIQSD
FTRNSDIEQVAKIINDSGIPLHLLVQNAGMKSPPRPLTEYDCDSIDEVFQVNLLAPMKLT
ALLAAQMPEKSRILFVTSRAATLKLKESSTYCASKAGLDEVTAIVRKELAEKNIGVSCVI
PGEVDTRIQKILRETTSFHLHKMFDEAYQSGQLISPETCAEFLKWFLCDLSFDEFKQSNM
PVSIYEEWHHPFWLKDRNKLPPFPF
>A0A4W6CR99|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Lates calcarifer|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASNPDKTFKVYATMRNLAKKERLLECVKGLHKGTLDI
LQMDVTDRQSILDARDRVVEKRVDILVCNAGVGLMGPLELQSLDSMRQILEVNLLGTIQT
IQAFLPGMKAQGHGRILVTGSTGGLHGLPFNEVYCASKFAIEGACESLAVLLLHFNIHVS
LIECGPVNTDFLVNLQKADLGDTTLQQVDTHTLGLYEKYLQHCDSVFQNAAQDTEDIVKV
FLDAIQSPSPAFRYFTSGVVPPLTQLKITEPDGSLCIHAMSKIIFSAEEK
>G4YKX4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Phytophthora sojae (strain P6497)|TrEMBL
MLSFGSGDSAQVAIVTGAGRGLGRAWAQALAARGVRVVVNDNDADASLVEGVVQAIRSRG
GVAVGDRNSVTDGAEIVKTAMENFKRVDILINNATVIRDGSFRKMTLEHWDDVYRSSLLG
TFSVTQAVWPIMRQQKYGRILNCVSGAGLYGNFGQVNYAAMKMGLVGFTVALNREGIKYN
IAVNAVSPVAGTRLTQPVWPEDVYTELTPELTSPIIVYLCHSSCKDNGELFELGGGWVGA
LRLQRTHGVGFPTDPKQFTPELVAEQWRDVVDFSRVTHPTSTQDSFEPMMRNVTAPPKSL
TTSRSSECAEVFDRLRATLQEKGHALSKQISGVLEWHINKEVWTITLLHGKGTLLEGRNP
RLAPDLQIHMDEQDFLDLAAGRLRLQQALIRKKLRLQGNLKMAMKLQPFADLLLQQHQAR
L
>A6T2N1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Janthinobacterium sp. (strain Marseille)|TrEMBL
MKTVLITGCSSGFGLEIAKYFLEHNWKVIATMRTPRADVLPQSEHLRILPLDVTDASSIR
RAVEEAGPIDALVNNAGVGMLGPFESTTMDAVREVFETNTFGTMAMTQALLPQFRARKSG
VIVNVASSVTLKALPLLPVYTASKAAIVAFTASLALELQEFNIRVGTVLPGMAPETAFAT
NAHARVAQTFPDDYAATMNAVLSGFQNYQGEVTHAIDVAKVVWQVTQDNKTAFRIPAGAD
AVQWFEQS
>A0A379IS60|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pseudomonas mendocina|TrEMBL
MNTASKGTALVTGASSGIGALYAERLAQRGYDLILVARNRERLNDLARRITDDTQRVVEV
LQADLGDAASLATVEAKLKQDASITLLVNNAGIGTHTPLLASDVGLMTRMIDLNVTALMR
LSYAAIPGFVERGNGAIINISSIVSITPEVLNGVYGGSKAFVTAFSQSLHHELADKGVRV
QAVLPGATATEFWDNGGLPLEHLDPAIVMPASALVDAALIDFDRGELISIPSLHDASQWH
AYEAARKAMFNQLSTNQPAPRYSVQR
>Q9VMH9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MERWQNKLAVVTGASGGIGAACARAMIGAGLRVVGLARREAKLKELRESLPRELQANFIP
RRCDVSKEDQVQSSFDWIERELEGADVLLNNAGITRETELVTPSNTQKLKEVIDTNVMGV
IWCTREAFNNMKRRGGEGHVLIINSIAGHQVLNFIDVLPSFNIYPATKFAITAITETYRQ
EFQLHSNKIRVTGICPGAVNTNIFPEEIHFYVKDMARLEPANIADAVMYALRTPPHVQVH
EITIKPMGEMF
>A0A2T6IUP7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii TgCATBr9|TrEMBL
MESLAWRLCVYTLTWLAILGDADDLLQASRYKRDGSFLVPPHIWHVETAACRWMIHQRPN
VFRRLEADLRTESAFVGANHSQSWGDVLDACWSSSSFVSRALCLGVASFRGAAFALSAFH
SWREREKAQERKLAVLVTGSSSGIGLQVTRLLLALDFYVIGTRLHSEDPWRVFEEICGGS
SRLLLLPMDVTNAEDVARAVEATKKFLRENDVSGLYALVNCAGIWNWNFIQTQSPQETEK
SLKTWRELFDVNLLGAVRVMHAFLPLMQARAVFVGSILGRMSSPGQTAYCASKAAVRLLA
EGARSDARDAGVNVVLVAFLAEVRVAPAQHVKSSTCVFAKETLTLCHPGRRRRTRGQVSP
RHPRGCFYRPVQSSAGARLSARANRERNCRLHSLCSDAAHCSLCWMGYVRMETA
>A0A063BBB9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia sp. lig30|TrEMBL
MKDFNDKVAAITGAGSGMGRALALQLAQARCHLSLADRNAAGLAETERIVRAIAPSVRVT
THVLDVGDRDAMFAWADETAHAHGGANLIFNNAGVALSSTIDGMDYGDLEWIVNINFWGV
VHGTKAFLPYLKASGNGHVINTSSIFGIFAQPGMSGYNATKYAVRGFTESLRQELDMMKC
GVSATCVHPGGIRTNIAQSSRVSKNMVGFMVENEQQGKDTFEKFFITTADDAARTILHGV
RGNARRVLIGRDARAADWMARILPAAYQALVVLATRHEAAKARRRAARTAGATYNNTGKQ
GEPS
>G1RLG6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Nomascus leucogenys|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHRKVFGDCPANAEAGAGPGG
GAGPGAGAEAGASGVGDPELGDPPAAPQ
>D3VH46|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / CCUG 14189 / LMG 1036 / NCIMB 9965 / AN6)|TrEMBL
MSMFNDLKGKRVVVTGGGRDFGQAISVWLAREGAHVDLCARQLASAEATCDIIRSEGGIA
RSYQCDISDAQSVKVFAEQLQQDNQPVDILILSAAQWLEGYLSDEDSDADIISTMNSGAT
GSMLLTKALLPSLRESQSADIIAMVSVCGISHFTQSVAHPVFFAVKHAMSGFCQTISHQL
SKDNIRVTGIYPPDFEVNGFDEVLDDHKTMGQQLLNGRSIWETIRFVLFQPRSCHISEIY
FQGPTREDLE
>G1NUM7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Myotis lucifugus|TrEMBL
MDRTVVLITGCSSGIGLQLALRLAADPSRSFKVYATLRDLSTQGPLWEAAGAHGCPPGSL
KTLQLDVQDADSVAAARARVTEGRVDVLVCNAGRGLLGPIEVHSAEAVGSVLDVNLVGMV
QMLQAFLPDMKRRRSGRILVTGSMGGLMGLPFNAVYCASKFAIEGLCESLAVLLPPFGIH
VSLIECGPVRTAFQGKVQDGLDAALGSADAQTRDLFSQYQRHFEQVFREAAQDPEEVTEV
FLAALRAPKPALRYFASERILPLVRLRLADPSGCSYVAAMRRAVFGDKPAEGPEGAQAEA
GAGELGRPESSAPPAAPK
>B2IVM9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MPTALITGASSGIGKAFAQELAARNTNLVLVARSKEKLSQLAKQLQEQHKIQVDVIIQDL
TEPNAAATVFDATKAKGLTIDLLINNAGFGYYGDFAEGDGERQIKIVQLNILALVDLTHK
FLPLMRQRRSGSIINVSSITAFQPIPYLSVYAASKAFILSFSEALWAENRQYGVRILVTC
PGPIETNFFAEANFPPALASSTDKVYSSEKVVWECLDALEKGYPTVISSDTSTQIRSKLS
RLVPRKLLLNILAKHFKA
>A0A8C1DJ96|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cyprinus carpio|TrEMBL
MEQKVVLITGCSSGIGLSLAVHLASNPSKAYKVYATMRNLDKKQRLMESVRGLHKDTMAI
LQMDVTDQKSILDAKRNITEGRIDILVCNAGVGLMGPLEAHSLDTIHAVLDVNLLGTLRT
IQTFLPDMKRKRHGRILVTGSMGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLMNLKRTEPSEEALEVDAHTRSLYDQYLQHCQAVFQNAAQDTEDIIQVL
QQAATQTPFLRYYTNRALLPMCSLKLTSMDGSQYIRAMSKLIFSAPNTDPQI
>A0A4X2M3D1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Vombatus ursinus|TrEMBL
MERKVVLITGCSSGIGLHLALRLAADPSGSFKVYATLRDLGSQGPLWEGARARGCPPGSL
ETLQLDVTDSCSVAAARDHVTEGRVDILVCNAGRGLVGPLEAHTVEAVGSVLDVNVAGTV
RTLQAFLPDMKRRRAGRVLVTGSIGGMMGLPFNAVYCASKFALEGLCESLAVLLPPFGVH
VSLIECGPVRTAFQEKLEGGPGGALGSTDLETRALFSRYQSHCERIFREEAQDPEDVVEV
FVRALSAPRPVLRYFSTERFLPLAELRLSDPGGSQYVNAMHRAVFSEPEEGEAGSEAKGL
ESP
>A3LP20|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)|TrEMBL
MSLSADGFNGSQLFELLGAGLADETLKKKAIAGVKAVIVITLKNKEGKEVSWLLDLKDAG
TVKKFEGAAPKGDVQLLLKDADFVKLAEGKANGQKLFMNGKLKVKGNMMKATAIEGVFKT
LDPRPKL
>A0A291T641|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Streptomyces malaysiensis|TrEMBL
MRDTSAGRAQALRQLAAGEGIGLRTVALDVQSEESVQATVATVLAEAGELDVVVDHAGHL
AIGYVEAFATDDVAHLFDVNVLGAQRVNRAVLPHLRARARGRARARGTLLYVGSTSIIDA
PPSSDHTSPPRRRSM
>C1L7P4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Schistosoma japonicum|TrEMBL
MRTSTNDMDASSTPHFIKHNFFIFTITLIITWFIFKLLQLLKICLVYTVAKWCFSKRKSL
RKAGEWAIVTGASSGIGEAYAEELAKEGLNILLISNDESQLRLVSERISTDYHVETRIVV
ADFTQNNVYDVIRPAIQQLSTIACLVNNVGMGLPIGPFVGGTQSPNEQSIHDIIHCNVLS
TAMMTQIVLPKMLSQKGSNPGIINIGSFTGLKVLPYASMYAATKAFIIQLSRCISAEKYS
RDVIVQTICPLVVSTKLSFL
>A0A125YR36|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii (strain ATCC 50853 / GT1)|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALVRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKAMAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>F4CAL2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sphingobacterium sp. (strain 21)|TrEMBL
MSKIVFITGASKGFGKIWAEALLKRGDKVAASARNISALADLKSAYGDSILEVKLDVNSR
EDVFSAVKKIKDHFGRIDVVINNAGFGLFGTTEETSEQQARDQMETNFFGSLWVAQAVLP
IMREQRSGHIIQVSSFLGLTTLPLLGLYNASKFAVEGLIETIGSETTHLGIKTTLIEPNG
FATDWAGASAVQTSSEITDYNPVRAAFAESGDNPDTWGKPEATVEPVLNIIDSENPPKRI
LFGRIAYQVINDVYTKRLEDIQNWKQVSIAAHGH
>A0A7X6AUE7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Streptomyces malaysiensis|TrEMBL
MSNIVLITGASSGFGALTARALADRGHTVYAGMRRTTTRNAGQVRAAADYSRAHDVDLRS
IELDVNSQQSVDTAVAQVITEHGRIDVLIHNAGHMVTGPVEAFTPEQLAELYNVNVLSTQ
RVNRAALPHLRAAGRGLVVWVSSSSVKGGTPPYLGPYFAAKAGMDSLAVSYAAELARWGV
ETSIVVPGSFTSGTNHFAHSGRPEDTDVDAAYETKYPGLVDQVAKKLADLAPADADASMV
SDEIARIVALPAGRRPYRVHVDPADDGSEEVSDVADRVRSEFLTRVGLADLLTV
>B9TNI3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ricinus communis|TrEMBL
MSTLNEKPVWFITGCSTGFGRELARKTLSLGYPTVITARKTSAIQDLADEYGDLALILEL
DVTNSDQIAGATRRAISHFGRIDVLVNNAGIGYFGSFEESEREEVRKMFDINVWGVADMT
RAVLPAMRSRGTGTIVNISSVGGILAFPALSFYNATKFAVEAISESLSQELAPLGIKVLV
VEPGPFRTDWAGRSANQAPQTIDAYTATAAARTEMIRGYSGKQPGDPVRAADAIVKAVES
ENPPLRL
>H0X6D5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Otolemur garnettii|TrEMBL
MNRTVVLITGCSSGIGLNLAVRLASDPSGSFKVYATLRDLKAQGPLWEAARARGCPPDSL
ETLQLDVRDSESVAAARARVREGRVDVLVCNAARGLLGPLEAHSEDAMMSVLDVNVAGTV
RTLQAFLPDMKRRRSGRVLVTGSLGGLMGMPFNDVYCATKFALEGLFESLAVMLPPFGIH
VSLIECGPVHTAFQEKLEGGLGGALDRADVQTRCLFSRYLVHWENIFREEAQDPEEVTEV
FLTALRAPQPALRYFSTNRFLPLMRLRLDDPSGCSFVATMHRTVFPDEPAGAEAGAGGPE
APESSTPPAAPQ
>W6K9Z0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Magnetospira sp. (strain QH-2)|TrEMBL
MQKTILLTGATDGIGLETAKMLVGAGHRVLLHGRNPAKLAQVEEDLSGIPGGGPLECYKA
DLSRLPDVEALAQAVIDKHSSLDVLINNAGIFKTPDPITPTGLDVRFMVNTIAPYRLTQR
LLPLMGCDGRVVNLSSAAQSPVDLRALAGGVELSDFEAYAQSKLALTMWSRTLAESLKES
GPLVVAVNPGSMLASKMVKEGFGVAGNDIRIGADILMRAALSDEFDGASGQYYDNDSRCF
APPHPDALDAGRCQEVVRGIEAVLEKAL
>G4FN14|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Synechococcus sp. WH 8016|TrEMBL
MTFPDNVNLRGSVYLVAGASGGIGKSLSTLLHSLNATVVLVDLSTELLVDLVDDLSKSNP
NAPKPQVFAADISSESSLKDLTTWYSAHFQHINGLVNCVGLLRTGESLKPISETSLSEWE
TIINVNLTGTFLLNRAFIPIMQKQRFGDIINISSVSGTQGRAFDGPYCSSKFGIIGLSES
IAAEVSSSGIRVQCLLPDAVNTDLWLQNGSTSIQPSLMMTSENVASVILYMLQLPADIYM
LNPIIAPMKRPKRRRNNN
>A0A073CM28|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Planktothrix agardhii NIVA-CYA 126/8|TrEMBL
MKTALITGASVGIGAAFAKELASRKIDVVLVARSQDKLEKLAEQLRSQYNIKAYLIPQDL
TQPDATQSVFDAISQQGLTIDLLINNAGFGDYGAFADRPLTKQVQMIQLNITALVELTHL
FLTDMKKRGSGAIVNVASIAGYHPYLIVRFMREQKPLF
>A0A2R9CKU1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pan paniscus|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG
GAGPSAVGDPELGDPPAAPQ
>A0A812DDZ9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sepia pharaonis|TrEMBL
MNSLLSLSCLWSPSLSLLPLFFLLFNSLCTFIFMDIRPNWHGGDIISFIILSHQPLYGIG
RSVCQLFAREGARIIAVDIQEEANMETLKSLAQGNHCAMTADISNVASVNEIFTKLKERF
NAVPTVIVNSAGITRDNILLRATEEDFNEVIAINLKGTYVVTQAAVKMMLSEKVEHGSIV
NISSIVGKGGNIGQCNYAASKAGVIGLTKSASKELSRFNIRVNAILPGFISTPMTDAVPE
KVLQKMLKFIPMQRFGQPEEVAETCLFLATKRSAYITGACLEVSGGLNI
>A0A4W5RGE8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Hucho hucho|TrEMBL
MEQTVVLITGCSSGIGLSLAVRLALDPAKMYKVYATMRNLAKKERLLDCVKGLHKDTLDI
LQMDITDQRSILDARDRVREKRVNILVCNAGVGLMGPLEAQSLATMRQILEVNLLGTIST
IQAFLPGMKAQGHGRILVTGSIGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLDNLQRAEPGDSSLQLVDAHTRSLYDTYLQHCGMVFQNAAQDTEDIVKV
FLDAIQSSNPAFRYYTNNALIPLSSPKISVLDGSQYIRTMSKIIFSTNGKGEQK
>A0A8C5PZ94|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Leptobrachium leishanense|TrEMBL
MEKQVVLITGCSSGIGLGLAVRLASDSQARFKVYATMRDLSKKERLLRCVKDCHVNTLEI
LQMDVTDQQSITATAGSIKEERVDILVCNAGVGLMGPLECHTYDSMKKIIEVNLFGTIST
IQAFLPGMKLRKTGRIILSSSIGGLQGVPFNDVYCASKFAVEGLCESLAIVLQHFHIHVS
LIECGPVSSNFMSNLQSCDPSDRTFQSLDSDTVSLYTRYLQHCHTIFQDVAQDTDDILQV
YLEAIEAPVPSLRYFTTQFFMPLIRLKMPCASGSDGGRSIITDPWKGYIQGYQ
>A0A3S4IQH0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella sainthelensi|TrEMBL
MNVAVITGAASGIGLALTQIHLQRSNFVVMVDKDSVKLKNEATRLSTLFPEKILEVACDI
THPNEVAHLAQQAQSKWGRIDWIYNNAGIIGPLAPIWDVCPEHIQKVMDVNLHGMIYMIQ
AFTPFLFEQTFNSHIINIASLYALCTGSQTVSLLHVKTCSFSFI
>A0A6J8CHL8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mytilus coruscus|TrEMBL
MLAGRLALVTGAGSGIGQAICQAFAKEGALVAMADVNKDGVHHVHETLKSISEGNHHPFT
VDVSSSASVATLLTDIRDRYMAVPTIAVNSAGITRDTYMLKMKEEMWDEVINVNLKGTYL
LNKAVSQGHCREQIKWWIHHQFINVLVGNVGQTNYGASKAGVIGFTKSAAKELAKFNIRV
NAILPGFIKTPMTEKVPEHLMQITQMLIPMTKLGEPEDIADACVFLASDKSRYITGATLE
VSGGLFM
>A0A8C0KKF1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Canis lupus dingo|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSRSFKVYATLRDLGTQGPLWEAARSRGCPPGSL
ETLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLEAHAAGAVESVLDVNVAGTV
RTLQAFLPDMKRRGSGRILVTGSMGGLMGLPFNAVYCASKFAVEGLCESLAVLLTPFGVH
VSLIECGPVRTAFLEKLEGVPGGVLDGADAKTRHLFSSYRRHSEQIFREAAQDPEEVTEV
FLTALRAPRPALRYFSTERFLPLAHLRLADSSGRSYVAAMHRAVFADQPAEEAAAAADPP
>A0A1C3ST38|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Lactococcus piscium|TrEMBL
MMMKKVVAITGASNGMGFEAAKLFAANGWLVYGGARRVEKIPIRPNVHALSLDVTDNSSN
KAFIQTILAEAGRIDVLINNAGYGEYGPVEDIPLDNARNQFETNFFGAADLGQLVLPIMR
QQESGRIINVSSIGGDVYMPLGAYYHATKAALQHWSDSLDMEVKQFGVRSITVQPGLTRS
GWGDIAMANAKKNLIATSVYTPLLDRVGGLLSTNAHAIGASSESLAALFYTAATDKRVKR
RYFHSLSDRTLVWLARSHPNLFKKGFETVFKYLGKRSDKA
>A0A068R8C9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xenorhabdus poinarii G6|TrEMBL
MSYSMLNGLKGKRVVVTGGGRDFGQAISVWLAREGAHVDLCARQLASAEATCDIIHNEGG
SARSYQCDISDAQSVSVFAEKLLRDDLPIDILILSAAQWLEGHLSDEDSDAEIISTINSG
ATGSILLTKALLPSLRKSQGADIIAMVSVCGISHFTQSVAHPAFFAAKHAMSGFCQNISP
QLSKDNIRVTGIYPPDFEVNDFDEVLDDHKTMRQQLLNGRSIWETIRFVLSQPRSCHISE
IYFQGPTREELVLSL
>G8TZE1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sulfobacillus acidophilus (strain ATCC 700253 / DSM 10332 / NAL)|TrEMBL
MTPPPNPVVCITGSSSGFGLEATIAFARRGYTVVATMRDVSRQTALVARLTPLGLLSRVL
IVPLDVTDAASIRAAVDTIDQRLGCIDVLVNNAGIAVGGFLEETSEVAWRRLLETNLLGA
VTVTNTVLPMMRAQQQGRIIFLSSLGGLVPTPFLGAYCAVKFALEGYAETLRLELAPFHV
DVVLVEPGAFQTSIWQTPLTNERTIPDYDHVRDSFMTLYQETLSKHLKNPQVVANRLVSI
AMTRHPRLRYPIGFDAWQEIYLRKLLPWRLYEQLIRKILNLEPRGSGGNK
>G0QWG0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ichthyophthirius multifiliis (strain G5)|TrEMBL
MKIQLLTSIYSPKIAHDQLNKSPAKVQYTFSKTNRFQKTRLSYCQSAFYQLKSTLNQRAT
NLGLGRKSDFTKKDKDIPGPNQYLIKSSFDKQQSIQKGISFKLGREEISFRKMNEYTSVP
GPGHYNQDDSKQKRLYHYSLGRNTQSTCNIFLLKIKICIQIELIPNYIVKFKDNPGPGTY
YIQGMNKTGKYFISKYNTSRAAVFSPSTQNRFQFLYKGKQSPGPGQYEYEGLSKKGIYYN
SKLRTTSGGKFSQSYRDTIGIRVKSEVPGPGSYRVVSEFGDTEFPPNQSVIIITGASSGI
GRELALRYAQQNCKLLICSRDIKKLIEVQEMCNQLGGITNVIKCDVSQEIDCKSLIEECI
KLYEKIDILILNAGINAHSPFQEIEDIQIFRKIMDTNFFGYVYPTKYALQHLLKNKGQIV
VLSSISGEIGLPYRSAYCSSKFAVTGFFESLRIELNQNDISITIICPPSVKTDMRNHDLL
QKYQQNDDELNRMSVEECVKIVMFAIKKRARKIFFPFKAYFAVYLRPFFPDYVDRKLKQA
AKL
>G7LRH4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Brenneria sp. EniD312|TrEMBL
MQKTVLITGCSSGIGLIAAQDLQKRGYRVLAACRRPEDVARMAELGLEGIELDLDDPASV
EKAAAEVIALSGNRLYGLFNNAGYGLYGALRDISRRQLARQFSSNLFGTHQLTQLLLPAM
LPHGEGRIIQTSSVMGLVATPGRGAYAASKFALEAWSDALRMELHGSGLHVSLIEPGPLT
TRFTANVDQTRADRPVTNPGIARRFTLPPEAVLPKLRHALESPRPRLRYPVTLVAHALSW
LRRLLPGRCLDNVLRTRS
>Q6DKA5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xenopus laevis|TrEMBL
MHVILEILWLLLVIFYSYLESFVKLFIPLKRKCVKGEIVLITGAGHGIGKITAKIFDELQ
SVLVLWDINKQGLEETAAECRKSGATVYTYVVDCSKREEINTAANKVKQEVGDVTILLNN
AGVIFCADVLTLQDQQIEKIFEVNILAHFWTTRAFLPSMLRNNHGHIVTVASSAGFVGVP
FMVDYCSTKFAALGYHKALTAELSALGKSGIKTSCLCPVFVDTGFVKNPSTRFAPVLQPE
DVARTLVDGILINKKMICIPPTVSVLPVLQFFLPERALNALNEFQSIKFEAKVHSRDKDK
>Q1JQD0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bos taurus|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSQSFKVYATLRDLASQGPLLEAAQSRGCLPGSL
ETLQLDVRDADSIAAAQARVTEGRVDVLVCNAGRGLVGPLEAHKEGSVDAVLDVNLTGTV
RMLQAFLPDMKRRRSGRILVTGSIGGLMALPFNAVYCASKFALEGLCESLAILLQPFGVH
VSLIECGPVHTPFPEKVEGGLGGMLDRADVETRDLFNRYRRHCERVIREAGQDPEEVVEV
FLQALRAPRPALRYFTTERFLPLVQLRFSDPSGSSYVAAAHKSAFHDKAAEGSDGAGAET
EAGKLEASELRAPLAPQ
>B7PUW1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MCMRPYVQERARRDVVLHVFSAVCLLILWRCLPPDARFLLGWVGTILTFGALTLAVAWLL
ERFLPNPKLDPTGKAVLITDLWAVVCNAGVNLFLEFEWMSQRDVSWMFDVNVHGTVRVVR
AFLPLLRRSRGRLVLVSSYAGKNAHPVR
>D5A7S2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MGANEPNQDGQRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICT
IAPGLFNTPMLAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLLNGEVIRIDG
ALRMMP
>B9RMQ8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ricinus communis|TrEMBL
MAVEVQDFILIAVSGLGFISLIKQIFIFWRWVWVMFLRPPKNLKKQYGSWAIITGSTDGI
GKALAFELASKGLNLVLVGRNPSKLEATSHEIKARSGAKQEVQIKTIVIDFAKSSGEETS
RKIEDGIQGLDVGVLINNAGLAYSYPMYFHEVDQELMDSLVKVNAEAATWVIRAVIPAMM
RKKKGAIVNIGSGSSVVVPSYPLIALYASTKAYLAMFSRCINLEYKHHGIDTQCQIPLFV
ATKMTRLKSSFTVASAEMYAKASIRWIGYEQLCTPFWAHSFEWFILQALPDSVLDWMLFR
IHNYLRKKGLENDALLNQEINVYDILHLSLL
>A0A2G8XSK9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii COUG|TrEMBL
MRLCQGNIDFMVSFSLCATQSRELHERIYSTKASRACTAQPPNLDRLLSLLPLRFLFLLL
LVHFLVFLFVVVDIRLLSTLGLRGALHRQPPGAAPTNAGTVVSSASARMFLSPSAVSELP
DVVQRLVSSLT
>B9SW05|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ricinus communis|TrEMBL
MFNNAGTAPENPSLSISDVEYNSYKKVFDVNVYGSFLGAKHAASAMIPVRKGSIIFTSSV
ASVTHGNLPHLYVASKHALVGLTKNLCVELGQHGIRVNCISPYGVATPMMTEGMGGIDKK
MVEDIMGASANPKQAVLEANDVAEAALYLGSDESKYVVKFGCGWWI
>A0A654AS54|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia sp. 8Y|TrEMBL
MMNRENPVWLITGCSTGFGRELANAVLERGWRAVVTARDPSKVQDIIKGHEDRAIVLPLD
VQKRDQIAKAVEQSMQRFGRIDALVNNAGYGYLAAIEEGEDDVVRDMFETNVFGLVDMTK
AVLPVMRAQKSGIVINVSSIGGITSFAATGYYHGTKYAVEGISESLATELKPLGIDVLIV
EPGPFRTNWAGPSIKSSATEIADYAATAGERRKQTAARSGNQAGDPVRAAHAIIEAATAD
TPPLRLLLGKTALELARKKLDLLKRDFDTWEKTTIGADFPENEA
>L8MZS4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pseudanabaena biceps PCC 7429|TrEMBL
MAKTVLITGTSSGIGRATALYFQKQGWNVAATMRSPDREINRTDSLAKLDRVVCIALDVT
NQTSIAEAIAAAIARFGTIDVLVNNAGYATLGAFEASTPEQIQRQFDTNVFGLMAVTRAI
LPHFRDRQQGVLVNVASIGGRVAFPLYSLYHATKWAVEGFSEALQHELLSFNIRVKIIEP
GPIKTDFYERSSDRASNAGFPEYQPFSDRVLSNLDRIGTTGAPPEVVAKTIYLASTDKSW
KLRYPADPLAKQLLFLRKILPDFIFTKIVRQSTKV
>A0A8C8JYY9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Oncorhynchus tshawytscha|TrEMBL
MEQTVVLITGCSSGIGLSLAVRLASDPAKIYKVYATMRNLAKKERLLDCVKDLHKDTLDI
LQMDITDQRSILDARDRVREKRVNILVCNAGVGLMGPLEAQSLATMRQILEVNLLGTIST
IQAFLPGMKAQGHGRILVTGSIGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLDNLQRAEPGDSSLQQVDAHTRSLYDTYLQHCGMVFQNAAQDTEDIVKV
FLDAIQSTDPAFRYYTNNALIPLSSPKISALDGSQYIRNMSKIIFSTNGKGEQK
>D8P3C7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ralstonia solanacearum CFBP2957|TrEMBL
MRLHIQHGTSQEPIYRSSNSPVQKETAMSNSKVVVITGVSSGIGRATAAKFALRGCRVFG
TVRNLAKAQPVPGVELVEMDIRDQASVQQGIQAIIAQTKRIDVLVNSAGVTLLGATEETS
IAEAQALFDTNVFGILRTTQAVLPHMRVQRSGRIINISSVLGFLPAPYMGLYSASKHAVE
GMSETLDHEVRKFGIRVVLVEPSFTKTSLDINAPHAVSKVSAYDDERSVVSQAIQKSVQK
APEPDGVASTVVDAALGAWKMRRTPKGEASLLSKLRRFMPAGPVDASLRKTFGLS
>A0A3Q2UU48|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Haplochromis burtoni|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPDKTFKVYATMRNLSKKERLLESVKGLHRDTLDI
LQMDVTDRQSILDARDRVVEKRINILVCNAGVGLMGPLEVQSLNSMRHILEVNLLGTIQT
IQAFLPQMKAQSQGRILVTGSTGGLHGLPFNEVYCASKFAIEGACESLAILLKHFNIHVS
LIECGPVNTDFLVNLKKTELGDTSLQQVDTQTQRLYEKYLQHCRSVFQNAAQDTEDIVKV
FLDAIQSPSPAFRYFTSTTGPPVTQLKATEPDDSYISAMSKIIFSTEEQ
>A0A0W0VGJ1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella jordanis|TrEMBL
MNNKSKKHVIITGGSSGIGKALACYLAQQGHNISIIAQDQNKLTAAVKDIENFSQNSSQV
LALSADVAKEFQVRKAIENAVKIHGMPDILITSAGFSYPDYFDNLNIDIFEKTMAINYLG
SLYAIKAVFPYMKKEKSGHIVLISSGAGLMGLFGYSAYSPSKFAIRGLAESLRPEFKRLG
INISIAYPPDTDTPQLAQENLTKPEETKKIVGPMKLRTADEVAKCIIKGINKNKFHISPG
VATYLIRLSHSFLFSPLNYYFDKIIQHHNAD
>A0A3G2S9L6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Malassezia restricta CBS 7877|TrEMBL
MSDVRGPVTLDVVLRALDQIPFSWPFVGILPLLALVYERRGAESWSGLVFPWPTVSEWHD
VLMVRHPFVVGCIIFILLRYTSMHMSRLALNLGEPRPDKPDWKEDVIVITGGSMGIGKEL
VQILSREHKARMAVLDVLEPTYAAASHGAPDILYIRTDVTSEQAVAQAQAQIIERFGRSP
SYVVSCAGVAPAGALLTSPVKMFTRAFDINAAANVVLAQAFLPAMISNNHGHFMTVASSA
SYFSLPNLCAYSMSKTAALAFLESLRAELRAVYKACRVRTSVVTPTKVRTVLAEGLNEGD
DDFLMPVLEPIQVARAMADTLNSGLSRNISLPLGSALLPYLRALPEWYRGALRAMGNTDA
LVTPESISRGQQALRGHQSNLDHMKKLGVHS
>A0A1Z5JQQ0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Fistulifera solaris|TrEMBL
MPRHDFQPPGAFFQNINSLIHEEPFGSILYCVYWSVVIGVCSPIAILLLQLRLLFRLLGW
VWESVCQYSSCDPKRHPTRELAVVITGCDTGFGRDVALRAAEAGYTVFAGCLKDESVTEL
NQLSSNINSFTMNVTIDVHVEKAVHIVSQWLDETTTQQRILHALVNMAGVGFCGNVDFMP
LNLFQTSMDVNFFGTVRCCKAFLPIFKSQATSNTYNDARILNMVSMAGLVPTSVGTSAYA
ASKYAVQGFSTAFRLEAMGFGIQVATINPSFHETNIVTGLSTQVEKLCADLPGAKREEYG
EEYLEWLLTQTRIPLLISWRAENVVQQTMNCLVNRTIPSEVVVGSDAKFVLVTLRIFPAW
FRDILFGIDSLRYAVPASMRRRKAKSD
>G0QN15|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ichthyophthirius multifiliis (strain G5)|TrEMBL
MGNTLTALEIKSTKFMSFNQNSNQILYIYQKAGSVIIITGASEGIGKELALKYALRQSRF
FIKKQKYIKIQIIKYLCNHLGGRTQIFQCDVTNEEQCKQMVEQCINYFQKIDLLILNAGV
NAHSKFMDFQDLKAFKQVMDTNFYGYVYPTRYALPYLVKTKGQIVVLSSLSGEIGLPYKS
AYCSSKFAVTGFFESLRTELKDKSVDITIICPPSVNFYLFFLIIKLKVKTNLRDNDLIQK
YKTQQMDETDDRMNVEDCAKIIVFASDKRARKVFFPFKAYMSAYMRPIFPDYVDNKILKL
SKF
>M5F3Q3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mesorhizobium sp. STM 4661|TrEMBL
MKQVVLITGASSGFGRMMANALAASGHTVHASMRGLSRKNAGQIAEVATYAQEHKVDLRT
VALDVQSDASATSAIGGKRRQ
>A0A087BTD7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bifidobacterium minimum|TrEMBL
MNRTVVITGSTSGIGSAFADLFADRGDALILVSRNVKTLRAQCMTLSERHPRGRFSYIVA
DLSDHTQVDAVCRRLADEPVDVLVNNAGFGMTGPFIQEDPRGIRSMIDVSVAAPTALARI
VAEGMVTRGHGRILNVASIAAFMPNPFGAVYAATKAYVLSLSEALSEELRGTGVTVTALC
PGPTSTHFAERSDMGRTRVFARNVMDAESVAQAGYRGMMRGRRRIVPGIPNHIVTGLSII
VPTIVVLRIAAWALRYTD
>B7PA68|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MRGTIRKPATFSRSYNFAAASVSKMFLPAMYAASTFFEGRLALVVGGGGGIGRCVCLAFA
KEGCRVIVADMNLEGATAVAKSLVGTGHEALQVDVGQSKSVALLFEDVSRLCSRPASIVV
NCVGIANPKTSFVDLSEEMFDNIIRVNLKGTFLITQAAARAMTAGNVPDGAIVNVSSFVS
KLCLPCRGEYAASKAGVVALTKVAAKELASQGIRVNSVLPVLTTTPMAGANRKPDERKKA
VEDIPLKRASRPEEVADVIVFLCGPGSSFMTGAAVDVAGGL
>A0A8C4FMG8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Denticeps clupeoides|TrEMBL
MDLKVVLITGCSSGIGLSLAVHLASDPSKTYKVYASMRNMDKKQRLLECVSGHHKDTLVI
LQMDVTDQQSIHRAKDSITEGRVDILVCNAGIGLMGPLEAQSEDVMRGILEVNLLGTIRT
IQTFLPDMKRRKSGRLLVTGSMGGLHGLPFNELYCASKFAVEGVCESLAILLHLFSGPSS
VSLIECGPVNTDFLVNLQRVEPRDSSLVEVDDHTLHLYEMYLQHCSSVFQNAAQDTEDIV
QVYLEAIQSPRPFLRYYTNHGLLPISTPDGSQYITAMSKIIFSSTTGGLCRFVCIFWSWC
AVLRVGSSGAGLNRGAAEADDVYFLICQLCMAFGVTNQKINGMFTV
>B9RMQ9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ricinus communis|TrEMBL
MLACINHLTTQPLWLPIVSFLGFLSLLNYSFTLLNWVYKTVLRQPKNLKENYGSWALITG
ATDGIGKAFAFQLAKQGLNLILVSRNLNKLKTVSSEIQEEFPSTKIKIMNLDFSSEDSSG
LVHVIEEAIKGVDVGVLINNVGITYPRARFFDEVDESTWMSIVKVNVEGTTRVTEAVLPG
MIERRRGAIVNIGSGASIVVPSHPLYTIYAATKAYIDRLSRCLYVEYKSCGIDVQCQLTD
GLMMNQVPLYVATNMTSRVALIEKSSLFIPSPQAYAEAAVRRIGYEARCTPYWAHSLQWF
FSRLLSEAVLDSWRLSIGIHRRGDIITSSTSAGVDGDGSRVV
>H2LGV5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Oryzias latipes|TrEMBL
MEKKVVLITGCSSGIGLSLAVRLASDPTKTFKVYATMRNLGKKERLLECVKGLHRDTLEI
LQMDVTDQQSILDAKERVVEKRVDILVCNAGLGLMGPLEVQSLNSMRHILEVNLLGTIQT
IQAFLAGMKAQEQGHILVTGSTGGLHGLPFNELYCASKFAIEGACESLAILLQHFNINMS
LIECGPVNTDFLVNLQKAELEDMSVEQVDGKTLSLYEKYLHHCNSVFQNAAQDTEDIVKV
FLTAIQSPSPAFRYFTNSVVEPPLTKLKAAQPDGVQYIKAMSEIVFSGEEQ
>A0A8C8WXF6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Panthera leo|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSRRFKVYATLRDLRAQGPLREAAQSRGCPPGSL
EMLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLEVQEAGAVGSVLDVNVAGTV
RTLQAFLPDMKRRRSGRVLVTGSMGGLMGLPFNAVYCASKFAIEGLCESLAVLLPPFGVH
VSLIECGPVRTAFQEKLEGGPGGALDGADAETRDLFSRYQRHLERIFHEAAQDPEEVTEV
FLAALRSPRPALRYFSTERFLPLVRMRLTDPSGRSYVAAMHRAVFAEEPAEESAADLGGP
ALGPPPAALQ
>G4I5T4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mycolicibacterium rhodesiae JS60|TrEMBL
MQGFAGKVAVVTGAGSGIGQALAIELGRSGAKLAISDIDTEGLAVTEERLKAIGVEVKAD
RLNVTEREAFQAYADGVKAHFGKVNQIYNNAGIAYSGDVEITQFKDIERIMDVDFWGVVN
GTKVFLPYLIESGDGHVVNVSSLFGIFSVPGQAAYNAAKFAVRGFTEALRQEMVLAKHPV
KVTTVHPGGIKTAIARNSTVAEGLDQAEMAKAFDKKLARTTPERAAQIILDAVRKNKARV
LVGADAKILDVIVRITGSGYQQLFSTVLPKLTPPMR
>A0A8C8YZ07|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Prolemur simus|TrEMBL
MERTVVLITGCSSGIGRHLALRLASDPSRSFKVYATLRDLRAQGPLWEEARARGCPPDSL
ETLQLDVRDSDSVAAARAHVTEGRVDVLVCNAGRGLLGPLEAHAAGAVSSVLDVNVAGTV
RTLQAFLPDMKRRRSGRVLVTGSMGGLMGLPFNAVYCASKFALEGLCESLAVLLPPFGIH
VSLIECGPVRTAFQDKLEGGPGGVLDCTDAQTRHLFSLYQRHCEQVFREAAQDPEEVTEV
FLTALRAPRPALRYFSTERFLPLARLRLEDPSGCSYVAAMQRAVFADEPLVLPGGSPGSL
RGGASGTKARRFQ
>A0A653TVI9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pseudomonas sp. 8BK|TrEMBL
MSQGKRYLLTGASSGIGAALARELAAKGYDLALAARREDSLHLLAAELQARFQRKVVVLP
LDVTDYAACQDAVGMAANALGGLDGIIANAGIGLAGQAGTGRFDRYPQTLETNLLGAIAC
LDGATQLFLEQGHGHLVAIASVAGKRGLPASAGYSASKAGLISYMESLELELYRTALDTT
LILPGYIDTPINQGTGPRPFLIDVERGAALIARHIEKRSSSAYVPGWPWALIGRLLPWLP
TTLIARAL
>A0A3Q3EBC7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Labrus bergylta|TrEMBL
MFRVKCPCVRQKNENTEKKDTSHNSILSSLFQLLFREQSTSEPDSMDKKVVLITGCSSGI
GLSLAVRLASDPNKEYKVYATMRNLAKKERLLECVKGLHRDTMDILQMDVTGQQSILDAR
DRVVEKRVDILVCNAGVGLMGPLEAQSLDSMRQILDVNLLGTIQTIQAFLPGMKAQGQGR
ILVTGSTGGLHGLPFNELYCASKFAVEGACESMAVLLQHFNIHVSLIECGPVNTDFLVNL
QKAELGDSSLKQVDPHTLSLYEKYLQHCGSVFQNAAQDTEEIVKVFLDAIQSPCPAFRYF
TSGDIPPLTKLKITEPDGLTYIGAMSKIIFSDEEQ
>A0A098GF26|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Tatlockia micdadei|TrEMBL
MKSLKDKTVWITGASSGIGEALAYEMARAGAKVILSARNEEELHRVRKNCASWEKHIVIP
LDLEKYHQLKNKAEEVWEQHGPIDVLINNGGVSQRYLAADAEVETDEKILNVNFFGAIAL
THPILKKMLERNSGHLVVISSMLGLYGIQARSAYSASKHALKGYFESLRNELVKTGVRVT
IVYPGYIKTQISKHALIANGTAYGKADKAHMTAIPPEHCAQRIRGAIEEDKPELIIAGTK
EKLGLLVSRFLPSLFRRLTPKIEV
>A0A3R7Z317|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii CAST|TrEMBL
MESLAWRLCVYTLTWLAILGDADDLLQASRYKRDGSFLVPPHIWHVETAACRWMIHQRPN
VFRRLEADLRTESAFVGANHSLSWGDALDACWSSSSFVSRALCLGIASFRGAAFALSAFH
SWREREKAQERKLAVLVTGSSSGIGLQVTRLLLALDFYVIGTRLHSEDPRRVFEEICRGS
TRTPEGGAEPRPAAAGERPRREETEEREDERERERKEDSRVESGESGETIGQTKQDGAEH
RRRWRGSRTQRRRPAEAREGADRERGDAGVTENRDQESVQTECGVGDEANSRLLLLPMDV
TNAEDVARAVEATKKFLRENDVSGLYALVNCAGIWNWNFIQTQSPQVRTAQKKLFAFLFA
FISRCVYSQ
>A0A3Q3BAU8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Kryptolebias marmoratus|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPNKAFKVYATMRDLTKKERLLECVKGLHQDTLEI
LQMDVTDRQSILKARDRVVERRVDILVCNAGVGLMGPLELQSLDSMRHILEVNLFGTIQT
IQAFLSEMKAQGQGRILVTGSTGGLHGLPFNEVYCASKFAIEGVCESLAVLLQHFNIHVS
LIECGPVNTNFLVNLQKAELGDPALQQVDAQTLSLYEKYLQHCSSVFQNAAQDTEDIVKV
FLAAIQSTSPAFRYFTNGTTPPLTELKVTDPDGTQFIRNMSKVIFSAEEQ
>A0A085FG16|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bosea sp. LC85|TrEMBL
MSLPRMQPQDGVAWVTGASSGIGEAVALELAARGWTVAITARRLEQLEDLAQRATGLPGR
IVAHAGDVTDAAAMRVVVDAIESVHGPIALAFLNAGIAPATRRGVFDIAALEAALAVNTL
GAAKGLAAVLERMKPRGRGQIAVNASIAGFGGLPRAAAYGASKAATIYMCEALKFDCDRL
GIRLQVVNPGFVDTPLTRRHDFSMPLLMTEAVAARRIVDGFVRGGFEISFPRRLSWAVKL
ISLLPYPVYFWAVGRFTGQAKRERA
>A0A8C7PIJ2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Oncorhynchus mykiss|TrEMBL
MEQTVVLITGCSSGIGLSLAVRLASDPAKIYKVYATMRNLAKKERLLDCVKGLHKDTLDI
LQMDITDQRSILDARDRVREKRVNILVCNAGVGLMGPLEAQSLATMRQILEVNLLGTIST
IQTFLPGMKAQGHGRILVTGSIGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLDNLQRAEPGDSSLQQVDAHTRSLYDTYLQHCGMVFQNAAQDTEDIVKV
FLDAIQSSNPAFRYYTNNALIPLSSPKISALDGSQYIRNMSKIIFSTNGKGEQK
>A0A5K1UDC8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Equus caballus|TrEMBL
MDRTIVLITGCSSGIGLHLALRLASDPSRSFKVYATLRDLTAQGPLWEMARARGCPPGSL
ETLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLELHPAGAVASVLDANVAGTV
RTIQAFLPDMKRRRSGRILVTGSMGGLMGLPFNAIYCASKFAIEGLCESLAVLLQPFGVH
VSLIECGPVHTAFQEKLEGGPGGALDGADADTRDLFSRYLRHCEQMYREVAQDPEAVTEV
FLTALRAPRPALRYFSTERFLPLVQLRLSDPSGRSYVAAMHSAVFADEPAQDPDGARAEA
RDGEAGSPELGARPAAQQ
>M5CMI1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Stenotrophomonas maltophilia SKK35|TrEMBL
MSHTILITGASSGFGLMTAKALALAGHVVYASMRETRGRNATRVADIAQWADAHHADLRS
VELDVQSDASSQAAVEQVLAEAGALDVIVHNAGHMVFGPAEAFTPEQLMQQYDVNVLGTQ
RVNRAALPHLRRRGSGLLVWIGSSSTRGGTPPFLAPYFAAKAAMDALAVSYSTELSRWGI
ETTIMVPGAFTKGTNHFLHSGTPADTAIVADYENGPYAGVADQALKGLAGREPADADPEE
VARQIVRVVGLPHGHRPFRVHVDPSQDGAEVVNAVADRMRREMYTAIGLADLLSPRG
>H1WL51|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Limnospira indica PCC 8005|TrEMBL
MQIQKALVTGASFGIGETFARQIAAQKGDLVLVARSQDKLEKLAGELQSQYGVKVQVISQ
DLTEANAGQVIFDQVAGGPETVDLLVNNAGFGDYGPLDERSLTKQLAMVQLNVTVLVELT
YLFLGVMKARRFGAIVNVSSIAGYQALPYMSVYSATKAFVVNFSQAIWAENQDTGVRILC
LCPGPTESNFFENAEFPQSMKSSGNNYASAAEVVKETLSSLDKKDSTLVTGGISNQIIVN
LPRLMPRDIIASLVEKQFRPKG
>A0A3B5RCU4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xiphophorus maculatus|TrEMBL
MEKKVVLITGCSSGIGLSLAVRLASDTSKVFKVYATMRNLAKKERLLDCVKGLHQDTLEI
LQMDVTDRQSILTARDKVVEKRVDILVCNAGVGLMGPLEVQSLDSMRHVLEVNLLGTIQT
MQVFLSGMKAQGQGRILVTGSTGGLHGLPFNEVYCASKFAIEGACEKILKIKKYCSITVN
LHEDNLSCIFFDFLINLQKAELGDSSLQQVDGRTLSLYEKYLQHCSTVFQNAAQDTEDIV
EVFLDAIHSASPAFRYFTNSVMPPLTKLKVTEPDGMEYIKAMSKIIFADQDQ
>A0A1S7LJR5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Magnetococcus massalia (strain MO-1)|TrEMBL
MAKTVLITGSTDGIGLETAKMLYAKGHRVLLHGRSQEKLAKAQREIAQQPGEGQLESYLA
DLSRMVDVAAMAEQLTQAHSKLDLLINNAGVYNTPKAITPEGLDLRFVVNTIAPYLLTQR
LLPLMDAGGRVVNLSSAAQASVELDALAGRAELADGPAYAQSKLAITMWSHKLAMDLKAR
GPAIIAVNPASMLGSKMVQQAFGVAGGDIRIGADILVRAALSDEFANASGRYYDNDVGKF
AAPHPDALDGAKCRAVIDMIEKLLARLTV
>G0A7U0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Collimonas fungivorans (strain Ter331)|TrEMBL
MRAAIVNVPYTTYRSPPMKTVLITGCSSGFGLETAQYFLARDWQVIATMRTPREDLLPRS
ERLRVIALDVTDADSIRRAVADAGPVDVLVNNAGIGMLGALEGTTMATARDVFETNTLGT
MAMIQAVLPQFRQRQTGVIVNVTSSVTLKPLPLLSVYTASKAAINAFTESLALELKQFNV
RVNLVLPGRAPETRFGENAQPRMQSGIPEAYADLAKSVFAGWGQSSAVTRAQDVAEAVWR
AANDASSPVRIVAGADAVALAESC
>A5EGJ0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)|TrEMBL
MSSGDLLLHSPTRFSHALREELERLGPIKYLLAPNVAHWMFLRDWQAALPNAQVYAAPGL
ARRAQVRRSGLRIDRELTDVTPDAWSQDLQIVLISAPLFSEVELFHRPSRTLILTDLVQN
LAPEGLGAVRRTVARLLGITAPDGKAPAYLRLVLRLGGRAVRLAAARLITLAPERVIFAH
GRWFDTGGTQRLRASLGWLLDSAPEARRLMRDLRGTRVVVTGASSGIGRATALALAREGA
SVVLAARRENVLKDVALECETLGGRAIAVATDVTDADAVKRLAEQAVRTFGGVDVWINNA
GTGVFGPYQDADMALHRKTVEVNLLGTMNGAYAVLPIFLRQRRGTLINNISLGGWAPTPF
AAAYTASKFGLRGFSASLRQELTAHKDVHVCSVFPAMVDTPGFVHGANVSGRTLDPGPLL
YRPEDVAETFVQLVRTPRDEVAVGWPARLGQISYALARRPTEQLMSTAFRFLLSRANSAP
RSTGAVLAPIAAGTAVSGGWLGRKKLPPAGQLSRIGLAVGIGGIALMLLARRRPPSAPRA
RAHR
>A0A8C0G3T7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Chelonoidis abingdonii|TrEMBL
MEKTVVLITGCSSGIGLGLAVRLASDASRRFKGTARSGGLPWRQRRSPTKCPGAGGHCNQ
PPFPPKPGTHSLLVYATMRNLAKKERLLECVQSCHTSTLEILQLDVTDPLSLAAAVQQVQ
EQRVDVLVCNAGVGLMGPLETCSYQAMKNIFDVNVFGTIGTIQAFLPGMKRRKAGKIIIS
SSVGALQGIPFNAVYCASKFAVEGLCESLAVILQQFNMHITLIECGPVNTSFLANLQRSD
AEGSALQGLDPQTRALYSQYLQHCQSLFRDVAQDTEEVLQVFLEAICAPCPPLRSFTTQV
FMPLTQLKLTSPDGSEYVRAMHKFVFSAGEAQGDRA
>G6FV49|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Fischerella thermalis JSC-11|TrEMBL
MPTALITGASSGIGRAFAEELAAQNHYLILVARSEDKLNELANQLNQKYQIQVDVIAKDL
TEPGATNTVFEFTKEKALTIDLLINNAGFGDYGDFAETDEERQIKMVQLNVLALVDLTHK
FLPLMRQRRSGSIINISSIAAFQPIPYLSVYSASKAFVRHFSEALWAENRQYGIRILVCC
PGPTETNFFTEAKFPPAIVSKNTQLSSSEEVVKETLKALEKGDSTVVIGGFSTHLITKVA
SVVPRETLLNILEKQFKA
>A0A0N1NP35|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Actinobacteria bacterium OV320|TrEMBL
MALKDTSAKRCAWRSVMVTGATGGIGAATALRMAGLGWDVIGTVRSQEKADVLAAAAARR
GLGLRTVVLDVADPVSCQEAMARVEEMTGGGVWAVVNNAGVPQAGSVEDVSDEQARHLLE
VNLLGAMRICRLALPGMRRRGGGRIVNVSSGLGRVPWPMGGWYCASKHALSAITHCLRVE
TAHAGVRVSLVEPGAFATAMLDRAVADLADTRPSGGRAGYDRSRDLFTAVNQRVPGPEPV
ARVIAGAVSARRPRARYTVGLDARFLIPLHTMGDMGAALLVEASAEPGIIASTFMANSTG
WPAATLFNPYQAPGRPHSLDIDSEQLLASFLGLDTRALQWLKEHDTEGRVAGAGGDGHVA
GAGWRRWPGRTVRSSCRRTGGSAGRRCTGWQSPDVSRPTRSPAPSVHAATPAGAVALVRS
PGPPRT
>A0A8B7ETX8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Microcebus murinus|TrEMBL
MERTVVLITGCSSGIGQHLALRLASDPSRSFKVYATLRDLRAQGPLWEAARARGCPPDSL
ETLQLDVRDSDSVAAARARVTEGRVDVLVCNAGRGLLGPLEAHAASAVSSVLDVNVAGTV
RTLQAFLPDMKRRRSGRVLVTGSMGGLMGLPFNAVYCASKFAIEGLCESLAVLLPPFGIH
VSLIECGPVRTAFQDKLEGGPGGALDCTDAQTRHLFSLYQRHCERVFRETAQDPEEVTEV
FLTALRAPQPALRYFSTERFLPLARLRLDDLSGRSFVAAMQRAVFADESAEAGAGGLGAP
EPGAPPATPQ
>A0A3B4UZ52|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Seriola dumerili|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPEKTFKVYATMRNLAKKERLLECVKGLHKDTLDI
LQMDVTDRQSILDARDRVVEKRLDILVCNAGVGLMGPLELQSSDSMRQILEVNILGTIQT
IQAFLPEMKAQSQGRILVTGSTEGLHGLPFNEVYCASKFAIEGACESLAVLLQNFNIHVS
LIECGPVNTDFLVNMQKAELGNTSLQQVDTKTVSLYEKYLQHCDSVFQNAAQDTEDIVKV
FLDAIQSPSPTFRYFTSGGVPPLTQLKITEPDGSQCIRAMSKIIFSVEEQ
>F8L9S0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Simkania negevensis (strain ATCC VR-1471 / Z)|TrEMBL
MCRRVLITGTSSGIGLAITNQLLAAGHEVWGVARNPQESKHPFFHPCAIDLSDLDALPDK
LEPFLEVDALICNVGRGQFGNLEEFSYKQIRSLMDLNFLSHVFLIKKLLPHLKKQKRADI
VFIGSEASLAGKQKGTIYCASKFALRGFAQSLREECSRSSLHVSMIQPGMVRTPFYDSLG
FEPGEDDSQAILPEDIAEMVELILKMRAGTVCDEIVLSPMKKVVQKKTATIID
>K9SFP8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pseudanabaena sp. PCC 7367|TrEMBL
MLENIKTALITGASAGIGEAFAQRLAQEKIDLFLVARSDDKLQQLATQLSKEHGVRVEFL
AQDLTDLAATDHVFDQIQALGWPIDLLINNAGFGDYGEFADSDRHKQLSMIQLNILALVD
LTYQFLPGMQARGNGNIINLSSIGGFQPIPYMSVYSASKAFVLSFSEALWAENRDRGIKI
QALCPGPTETEFFKVAGFDQMPNTSGSARSVATPQAVVNESLRGLKSNQSVVVTGGLGNQ
VIVNAGRFLPREVLAKGIAQIFDPKSKQG
>F8LDB1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Waddlia chondrophila 2032/99|TrEMBL
MESQVVLITGSSRGIGRLTALELSRRGHRVYATMRNPEPIENVHVERLDVTDEKSIAEAV
SNLIEKEGRLDCVINNAGYGLLSPVDTATDDEIMKQFDVNLFGVIRVIREVLPQMRKQKS
GKIINISSVVGVVSNPAMGWYSATKHALEAVSASLASTVFPWNIYVSVVQPGSTATEFAA
NLKLEEGGGNSPYGDFSKKHQERMKNILTDGQPPEEVAELIADVVEDPKPHFRYQTSERA
KQIVSQFVVDPSGDQWLNQQKETFKGWINT
>G4I7C3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mycolicibacterium rhodesiae JS60|TrEMBL
MAITRPVALVTGANSGLGSYAARGLVDAGFEVVGTSRNIGGLGYGRGITFHELDVTRDES
VTAAVEAVIAQFGRIDVLVNNAGMGLAGASEENSIVQAQKLFDINVFGVMRMTNAVLPHM
RRQGSGRIINISSIFGLMPAPYMAAYSATKYAVEGYSESVDHEVREHNIRVLLVEPGGTR
TGFDDNTAKPDNALAAYERQRERSNQAVADQVNNGDDPAVVAKAIVAAATDSAPKLRYPA
GSARRLSAMRRFAPRGIFDKQLRKSLGVLG
>A0A087BCE7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bifidobacterium magnum|TrEMBL
MGYTLITGASSGIGREMALLCAEEHRDLVITARNEAVLNGLKKQIEEEYGVKVLVIPADL
SQSAAPQQLYDATTKAGIHVDMLVNDAGFSDWTRFLEADWNKTEAMMQLNMHAVAQLSYL
YGRDMVSLGSGKIVNISSIASAMPGPYMAMYYATKAFVRSLGVALAKELEHTGVTVTTIC
PGPVTTGFAKAANMHGKNFYTMAKAATPSQVAQFAYRKAMRGKALAYQGALAKACSVLVR
IAPLCLLVAGAATMNGGDPGKGANPLRK
>E8UAV3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Deinococcus maricopensis (strain DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34)|TrEMBL
MTSRRVVVLTGASSGIGRAAAEALAARGDALVLAARREDELRVLARTLDASGSRVVAGRA
DVAVQADREALIEAARAQFGRVDALVNNAGISIARGMWWDDPDPLRVLEVNLTAPIELTR
LVLPEMRARGRGHIVNVGSVAGRAATHGMYSASKFGLRGFSLALRRELLGSGVHVSLIAP
GFVRTELTAAAKLPMPGPDVVARAIADVLDRPRREVIVPRFYGPLAALEAALPGLGDAIV
ERIRARRYGA
>A0A7M4DXJ8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Crocodylus porosus|TrEMBL
MEKTVVLITGCSSGIGLGLAVRLASDSSQRFKVFATMRDLAKKERLLECVRGCHRDTLEI
LQLDVTNPASLASAIQRVPEQRVDVLVCNAGVGLMGPLETCSQEAIKAVFDVNLFGTINT
IQAFLPGMKCRKAGKIIITSSVGALQGVPFNAVYCASKFAVEGLCESLAIVLQEFNIYIT
LIECGPVNTSFLSNMQSMDPEGHELQGLDPKTYALYRQYSQHCQSLFQDAAQDTDEVLQV
FLDAICTPNPPLRCFTTQFFMPLTRLKLLSPDGSEYVQAMHKFVFSTSNSGQGPAGSGRL
YLGGGPGAPLLCVPGMRKDTEQGW
>A0A086Z060|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bifidobacterium actinocoloniiforme DSM 22766|TrEMBL
MSRSVVLITGATSGIGLATARMLAERGYEVYGAGRRIELLEGLRVLGVVPVRMDMSDQAS
IEAGAQAILEREGSIDVLINNAGYGSYGPVEQVPIEEVRRQFEVNLFGLARLTQLVLPGM
RAAGRGRVVNTSSMAGRMVTYMGAWYHATKYALEAFSDALRMETRGFGIDVVVVEPGAVA
TQWGPIAADHLQAAASHGPYSQQASRAAAGLRKLYASALITKPEAVARTLVHAATVKRPR
ARYTLGFGAKPLVALHALLPARAFDWMMVHAEDL
>A0A3B3W3I7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Poecilia latipinna|TrEMBL
MSMEKKVVLITGCSSGIGLSLAVRLASDSSKVFKVYATMRNLAKKERLLECVKDLHRDTL
EILQMDVTDRQSILTARDKVVEKRVDILVCNAGVGLMGPLEVQSLDTMRRILEVNLLGTI
QTIQVFLSGMKAQGQGRILVTGSTGGLHGLPFNEMYCASKFAIEGACESLAVLLQHFNIQ
VSLIECGPVNSDFLINLQKAELGDPSLQQVDGRTISLYEKYLQHCSMVFQNAAQDTEDIV
EVFLDAIHSTSPAFRYFTNSVMPPLTQLKVTEPDGMEYIKTMSKLIFADEDQ
>A0A378JCY5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella gratiana|TrEMBL
MKVAVITGAASGIGLALTQVHLQRDSFVVMVDKDSVTLKNEATRLLALFPGKVLEISCDV
TKPNQVTQLAQQVQNQLGRIDWIYNNAGIIGQLGPIWDLCPEHVQKVMDVNLHGMIYIIQ
AFIPFLFQQTFYSHIINIASLYALCTGSQTASYSMSKHAVLALSESLYFDLDRMKKPVNI
SVVFPSFTDTALLSHNEDTSSQFQEILKSLLSHSRPALDIAEYIIREVEQKKFYIFPDPE
VKGYCEDRTKAMIFEENPHVTNIEKLMSTLIKRQSKNPS
>A0A086ZQZ4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bifidobacterium biavatii DSM 23969|TrEMBL
MLLEDLRPNIRVLINNAGYEREGALRDMDPVDIRAMIDFNTTAMTLVNRVCLPYMGRGSF
AVITGSVSSFAPIPWQAVYSASKAYTRFLARALHEEERARGVNVMLFSPGNMDTEMNVRG
AASGKLARLPYLDLRRETAKALAKAERGCANYTPLMFYKLYHVFAKLVPTTLAVRVTSLR
SGGAVSRG
>A0A6J8BZ25|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mytilus coruscus|TrEMBL
MKRLRKVAVITGGNSGIGLSVCERLLTLHNNLELCLLCRNIHRAEAAKNALLVSHPKSSI
NIVVMDTSDVKSVLRAAQDLKRRYKGIDYLYLNAGIMPVTGVNWTNVVKGILSNCAHVLS
TGEGCLYHTDETTKDGLKNIFASNIFGHYTLIKELEDRLGGEKDTQIIWTSSRAAMKSAF
DITDIQHKHGENPYSSSKYVIDTVSVSLNNKLNKKRVYSHTTCPGLVMSNLTNGVLPYWI
WSILYPLLIVLRLFCPSLTCSSYNGSEAMVWLSTQNPQSLEPQDKFNSDVDIFGKTHVST
VKLDIDTKTEETVCNKLDELYKEFKTKYC
>S8FDJ8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii (strain ATCC 50611 / Me49)|TrEMBL
MESLARRLCVYTLTWLAILGDADDLLQASRYKRDGSFLVPPHIWHVETAACRWMIHQRPN
VFRRLEADLRTESAFVGANHSQSWGDALDACWSSSSFVSRALCLGIASFRGAAFALSAFN
SWREREKAQERKLAVLVTGSSSGIGLQVTRLLLALDFYVIGTRLHSEDPRRVFEEICRGN
SRLLLLPMDVTNAEDVARAVEATKKFLRENDVSGLYALVNCAGIWNWNFIQTQSPQETEK
SLKSWRELFDVNLLGAVRVMHAFLPLMQARAVFVGSILGRMSSPGQTAYCASKAAVRLLA
EGARSDARDAGVNVVLVAFLAEVRVAPAQHVKSSTCVFAKETLTLCHPGRRRRTRGQLSP
RHPRGCFYRPVQSSAGARLSARANRERNCRLHSLCSDAAHCSLCWMGYVRMETA
>D3HJ38|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella longbeachae serogroup 1 (strain NSW150)|TrEMBL
MKVAVITGAASGIGLALTQIHLQRENFVVMVDKDSVKLKNEATRLSALFPEKILEVSCDI
THPNEVAQLAQHVQSKLGRIDWIYNNAGIIGQLAPIWDLCPEQIQKVMDVNLHGMIYIIQ
AFAPFLFEQVFHSHIINIASLYALCTGSQTTTYSMSKHAVLALSESLYFDLKRMEKPVNI
SVVFPSFTDTALLSHDEHTPSQFKGILKSLLSHSRPAIDIADHIVQEVEQKKFYIFPDKE
VKGYCEERTKAMILQDPPYVTNIEKLMGALMKRQSQA
>A0A086L5G3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii p89|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALVRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKAMAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPTLRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>L7JVL6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Trachipleistophora hominis|TrEMBL
VLLIVKDVYAVLMIIGTYFFMSSFLIGKKICPGMLFTIFKIFVLFLCFQVIYLNFRFVAS
RILNYRVWKNIKGRWIMITGATDGIGKEMALILAKMRQNIIIVGRNAEKLAATQAEISKL
TQCKSILMDFAVEQSFDDVITDNIGMLINNAGVSSEYTKDFVDEERITQIINVNNLNAIK
LTQSVLKKMDKYSYIINIGSKVADFPCPLHVVYAASKRMLKSWSVSLAYELNHRYIHVEY
ISPHFVATKMSKIRKSNLFVPSAHDFAKSVVESVGTWWENTPYFYHVVQNLFLMFIPEIL
IGYAVYFKHSHIQKLALRKKNR
>A0A139XT35|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii ARI|TrEMBL
HPGRRRRTRGQLSPRHPRGCFYRPVQSSAGARLSARANRERNCRLHSLCSDAAHCSLCWM
GYVRMETA
>A0A1Z5JMD7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Fistulifera solaris|TrEMBL
MKMLYFNSNGNLSIFGRADDGRKNALLIIIDNSDLAVVSFMHLFISFDYQKMSIAFIKEI
PPVVAGLAGLGFLVALSLVVKVLSSTYNTFLRPGKDLKKLGKWAVVTGATDGIGKAYAMG
LAKKGMSIVLISRTESKLNEVKKEIETKYSGIEVKHIVCDYSKFDKKAQDELKKQLVGLE
VGVLVNNVGVSYRYPRYFHELPDDEVQNLLTMNIDSVVWMTRFVLPGMIDRKKGAIVNIS
SGSALYTLPLLAEYSGAKSFVEKFSRAINAEYKNKGITCQCQAPFYVATKLAKMRKSFSV
PDPNQFVALALKWVGYPDCVVQPFWVHALQGWVMHRVPDSILAWFIMNMHLAIRKKGINK
DLKLASEGKLE
>A0A7U3ZKP3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Runella slithyformis (strain ATCC 29530 / DSM 19594 / LMG 11500 / NCIMB 11436 / LSU 4)|TrEMBL
MATKQQYALVTGATAGIGYELAKLLAEDGYNLVIVARGQDGLDKTVKDLTEAYNVRVIPT
VKDLFDPKAAFELYEFVTFQGIHIDILVNDAGQGQYGEFIHTDIQRELDIIQLNISSLVV
LTKLFLKDMVARGNGKILNLASIASKMPGPLQAVYHGTKAFVHSFTEAIREEVKDSGVTV
TSLLPGATATDFFNKADMTQAKIVQDGKLSDPAEVAKDGYDALMSGDDMVVSGLSNKMQV
AMSNFMPDEMVAANMHKQHTPKEPEEK
>M3YFW4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mustela putorius furo|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSRSFKVYATLRDLRAQGPLWEAARSLGCPPGSL
ETLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLEAHTAGAVGSVLDVNVAGTV
RTLQAFLPDMKRRRSGRVLVTGSIGGLMGLPFNAVYCASKFAIEGLCESLAVLLPPFGVH
VSLIECGPVRTAFLEKLEGVAGGVLDGADAETRHLFSRYQRHLERIFREAAQDPEEVTXE
RFLPLAHLRLADPSGCSYVAAMHHAVFADDPEEEPNAAAPGGPELCAPPATAPQ
>B0EGA4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MDFLTNIILIGVFLFLLKMYCNGRQNLIEKDLKDKVVVITGGTHGMGIALVRELLKRHAT
VVSFSRNESLAQRISSELIKEFPNAQFEHITMDLGDLKIVKEATEMCIEKYPEIDYIIDN
AGILISPFTKTKQNLEGIIGINYVGHFLFNLKLLNALKIRHGRFIITSSIMAQFADKPIT
LDCKKDHFNCYQRYSQSKLALMMMAKELSLHGIEAVSIHPGVVVSNILNKYPTFIQWGYK
ILGFFIFKSVEDGIQTALHCIFSDSIVNGGYYKDCECSTLYKRAENTIERQEIWDKTYEI
IKPFL
>A0A674IDC4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Terrapene carolina triunguis|TrEMBL
MEKTVVLITGCSSGIGLGLAVRLASDASRRFKVYATMRNLAKKERLLECVRGCHASTLEI
LQLDVTDPLSLAAAAQQVQEQRVDVLVCNAGVGLMGPLETCSFQAMKTIFDVNVFGTIGT
IQAFLPGMKRRKAGKIIISSSVGALQGIPFNAVYCASKFAVEGLCESLAVILQQFNVHVT
LIECGPVNTSFLANLQRTDAEGSALQGLDPQTRALYSQYLQHCQSLFRDVAQDTEEVLQV
FLEAICAPCPPLRSFTTQFFMPLTRLKLTSPDGSEYVRAMHKFVFSAGKAQGDQA
>U2DZD3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Halorhabdus tiamatea SARL4B|TrEMBL
MAPTTGSETDGPVWFVTGASRGMGREFARAALDAGHAVVATGRDTDAVAEAVGESENLLV
AELDVTKLDDAESAAQAAVDRFGRIDVLVNNAGISYKGFFEEMTTEEIKHQLEVNFFGQL
YVTRAVLPVMRDQRSGHIIAISSGAGLSGFGFSSAYAASKHALEGWMDALHDEVAPVGID
TTIVNPGWFRTTLTSAESMPFTEPAIDDYDERRAEQMEWWNEQGGQQPNDPARLAEALVE
IAGEDDPPRRFIAGEDAIELAEETIDRLQNQIDAYRELSTSMAYDA
>A0A083ZJM6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhizobium radiobacter|TrEMBL
MTNTILITGTSSGYGKAIAELFLARGWNVIATMRRPSAARFAGDNGRLRVLPLDVTEEAS
IAAAIEAAGPIDVLVNNAGIGMVGAFEATPMSAIRTIFDTNSFGVMAMTQAVIPQMRKRQ
SGTIINVTSTVTLASFPLAAAYTASKQAIEGFTGSLAHELAHFNIGVKLVEPGYAPTTGF
TNNAILPLEQLLHDDYAAFARPVLEAFATPALTTRETDVAEAVWSAVHDTSGQLHFPAGA
DAVALAQKN
>B7PGB1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MTSPSTYDKLKMAAVDQGLFLIQDLLERLRRVESILAIVGLFYVGKTASAVTVRLLEGFR
VHILSQFRWHDLTRYGEWAVVTGGTDGIGRQYARELAKRGLNIILISRNMDKLRATAQEL
GKVRTHVIQADLSEGRHIYPEIGRQLEGKEIGILINNAGVMYDSPSLFLNVPEKKLVESV
NINMMAVMMMTYLVLPQMVERKKGVIVNISSISSFYPLPLMAVYSASKVFVDWFSMALDY
EYKGKGIIVQSLIPSYISTKLVRFSNFLSTPSLVVPDAQTFVRSSLQTIGVSKRTTGFWT
HGIQA
>A0A8C0E357|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Balaenoptera musculus|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSQSFKVYATLRDLTTQGPLWEAARSRGCPPGSL
EMLQLDVRDADSIAAARARVTEGRVDVLVCNAGRGLVGPLEAHEEGTVGSVLDVNLTGTV
RMLQAFLPDMKRRRSGRILVTGSMGGLMALPFNAVYCASKFAIEGLCESLAILLQPFGVH
LSLIECGPVHTAFPEKLEGGLGGVLDRADAETRDLFSRYLSHSEQIFFEAGQDPEDVTEV
FLQALRAPRPALRYFTTERFLPLIQLRFSDPSGCSYVAAAHQAVFGDQAAEGSDGAGAEA
GAGELGAPELGAPLAAPK
>A0A378IYK5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella feeleii|TrEMBL
MEKTALVTGATHGIGLALSKNLLSNGWLVFGTGRDLASLETTQALFPDFIPIQADFTQND
DIENVATTIKKTGLPLHLSVQNAGMKSPPRPLEQYTCGSIDEVLMVNLLAPMKLTALLSS
QMPSESRILYLTSRAATLKLKEGSTYCASKAGLDEVAAIVRQELEERNIGVSTVIPGEVD
THIQKILRETTSFHLHQKFEEIYQKGQLISPAVCAAFLKWLLCDLPFAEFKQSKMPVSIY
DKWHHQCWLTDANQLPACPF
>A0A835X5M5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Nitrosopumilales archaeon|TrEMBL
MDKVALVTGSSSGIGLETSLALAKDGYRTFASMRDTGKAIELQEAAKKENLSIDVIELDV
DKEDSIISAVKKVMSEAGRIDVLVNNAGYGQFGCTEDVPIEDFRKQFETNFFSIVRIIQE
VAPIMRKQGSGVIVNISSVVGRMGLPGSPAYISTKFALEGFSECLRYELGQFGVKTTIIE
PGVIKTNFFKSMHIPESKTDPKYKE
>A0A086QWF1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii MAS|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALVRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKALAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>W1J810|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xenorhabdus cabanillasii JM26|TrEMBL
MLNKLDELDGLKGKRVVVTGGGRDFGQAISVWLTREGAHVDLCARQLKSAEATCKIIQGE
GGITRSYQCDISDAQSVRNFANQLLQDSKPIDILILSAAQWLEGNLNDDDSDEDIISTMN
SGATGSMLLTKMLLPSLRKSQGADIIALVSVCGMPNFIRSAAHPVFFAAKHAMSGFCQTI
SHQLSKDNIGVTGIYPPDFEVNGFDEDLDDHKTMGKQVLNGRSVWESIRFVLTQPRSCHI
SAIYFQGPTFEDIKQL
>A0A1Y5PYH8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|uncultured Sphingopyxis sp|TrEMBL
MTELWLITGVSSGLGRSMAIAALEAGFAVVGTVRNEVDARSFENLPGCAHARILDVGDHG
AIPDAIEEIERTLGPVSVLVNNAGYGREGPLEAIAVSDLQRLYDVNLFGALRLCQAVIPS
MRARGAGRIINISSATTLGAAPAIGAYSSSKAALNCLSEVLAKEVGAFGIKVTAVLPASF
RTDWAGRSLTRTEEGDSHYGHLAETRAARAARDGRQAGDPARFAAAILALAADENPPLNL
LLGASALRGARARIAQMEAEVITSEPAALATDFDSPVDLSAA
>A0A2P6SAV0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rosa chinensis|TrEMBL
MKNLRYISMSKDLELFASKSSKIRSKQEYESFSGDIDYLSNQLRWLDWPDSPLQSFPSDF
YANKLVNLNIPDSHRITRLWEGRKNFSKLTRMNLRGCESLSGLPDFSGIPNLKELDLADC
ENLTTIPCNELQNLEILNVSRCSNLATFQTKASISHDRDGGSLALPKLHVLKIKGCNLSS
SDFIGSLDCLKTLTELDLSSNNFVSVPTLGKFVNLPRIDLNCCKRLREIPELPPNILEVN
ARDCESLERFSIWPKSLKMLEMDLCNCHRFSYSLGYDMEKMENILLNNQNNSPFTLVLPG
SEVPKWFHILKEVAANEKGLALTCAVSFEIPSKLNWENIGLALCSVLVEETFSIFIDDRA
VISINEELIDQRSNRHSPTPIGHMRLNYIPLSDEIKGKVDQNGWSRYHCRVQFYPVDQMK
SCGVHLICQPPNEYSNKIVMAAPPADESGMLDCLSWLSSPSIEDDCESLDTDVGLDIRHW
LS
>A0A378L344|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella quateirensis|TrEMBL
MKVAVITGAASGIGLALSQICLQRGIKVVMVDKDGSRLIKEANALIALFPGSVLNKTCDI
TKPDEIEQLMHYVDTHCGRIDWLFNNAGIIGTLAPVWELQPEQLSQVMDVNLYGMIHVIR
VFMPYLFNQQFHSHIINMGSMYGLCSGSQIAAYSMSKHAVLALSESLFYDLKRLEKPVDV
SVVFPSFTDTSLLSNNSAESHSAFHESLNSLLAHSRPASDVALHIIQEVELKRFYILPDK
EVKGYCEERTNAILRQENPYINNIEKLMNSLIKRKRILV
>W4AA75|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhodococcus rhodochrous ATCC 21198|TrEMBL
MAIKDLRGRKFLVTGAASGIGRALALAAAAEGAELVLTDLAADGLDDTVRTVREGGGSVL
HAAALDISDYDAVTAFAADVHDRAGALDVVANVAGTSVWGTVDALEHRHWKQMVDVNLMG
PIHVIENFVPPMIEAGRGGHLVNVSSAAGLLALPWHAAYSASKFGLRGVSEVLRFDLHRH
RIGVSLVVPGAVRTPLVNSVQIVGVDRDHPTARKLTSRFERHAASPEKVAGCILAGIRKN
RFLVYTSFDVRFGYWWARKFAPPYNVVMQLANNYFSRTLEAVRTRR
>A0A8C3HT05|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Chrysemys picta bellii|TrEMBL
MEKTVVLITGCSSGIGLGLAVRLASDASRRFKVYATMRNLAKKERLLECVRGCHASTLEI
LQLDVTDPLSLAAAAQQVQEQRVDVLVCNAGVGLMGPLETCSFQAMKTIFDVNVFGTIGT
IQAFLPGMKRRKAGKIIISSSVGALQGIPFNAVYCASKFAVEGLCESLAVILQQFNVHVT
LIECGPVNTSFLANLQRTDAEGSALQGLDPQTRALYSQYLQHCQSLFRDVAQDTEEVLQV
FLEAICAPCPPLRSFTTQFFMPLTRLKLTSPDGSEYVRAMHKFVFSAGEAQAAAGEFAPC
SSGSPEGAGVSQPHLFVSETRGCCTRAAGAASAV
>Q1LEN8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)|TrEMBL
MTQTHLGTALVTGASSGIGAIYADRLARRGYDLILVARNRDKLDTLARRITDDTQRVVEV
FPADLNDRQSLARVEEKLRQDASITLLVNNAGVGTHTPLLDSDVDAMNRMIDLNVTALTR
LTYAAVPGFVARGRGAIINISSIVGIAPEILNGVYGGSKAFVLAFSQSLHHELAAKGLRV
QAVLPGATATDFWETGGLPIEHLDKAIVMPAEAMVDAALVGFDRGELVTIPPLHAIEQWN
AYEGARQAMAGLLSTNTPAPRYATGR
>Q39DR0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MKEVILVTGASSGFGLLSAQALARAGHTVYASMRESAGRNAPRVAAIAAYAQEHGVDLRT
VELDVGDDASVGAAIDRVIADNGRLDVIVHNAGHMVFGPAEAFTAEQIAQLYDINVVSTQ
RVNRAALPHLRRQGRGLLVWVSSSSARGGTPPFLAPYFAAKAAMDSLAVSYAAELARWGI
ETSIVVPGAFTQGTNHFAHAGKPADAAVQAAYVDGPYAGVAEQALQGLAALEPADADAGT
VATAIADIVAAPAGKRPYRVFVDPSQDGAEEVFRVGDRIRREMFRNIGLADLLAARVGG
>A0A653J7F9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Novosphingobium sp. 9U|TrEMBL
MDLQKYGPWALIIGGSEGVGAAFAQLLAADGFKLVLVARKQGPLDELAAELRGQGAEVRV
LSADLAQPDVLAQVRGVTDDIEVGLLVYNAGANNTRGLFVELPEEVTGSVLAITVLGQAN
FARHYGALMVKRGRGGIILGGSLSSYLGSPTLATYTGAKAFSRIFSEALWAECAPLGVDV
LHLNIGFTATPAMARLGMPVDLAEPPETVAREGLENIANGPVWIVSTPGNLERARLISAV
DNRAEIVRSNAIPPRDKTAEAAREHQRLAAGD
>F4CNC3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190)|TrEMBL
MAAKVWFITGASRGFGREWAIAALERGDSVAATARDVATLDDLATKYGDRLFPITLDVTD
RDAAFAAVAAAHERFGRLDVVVNNAGYGHFGFVEELTEAEVRAQLETNLFGALWVTQAAL
PFLREQGSGHILQVSSIGGISAFPLVGAYHASKWALEGLSQSLAQEVAPFGIHVTLIEPG
GFATDWSGPSSRHSEAHPAYAALHEEVAAARRARLGTPGDPKASAAALLKVVDAEQPPLR
VFFGESPLGVAEKDYESRLATWREWQPIAIEAQG
>W5N3Z7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Lepisosteus oculatus|TrEMBL
MDKTVVLITGCSSGIGLRLAVHLASDPSKTFKVYATMRNLAKKRRLMDCVKDVHPDTMDI
LQMDVTDQLSVLNAKEKIEEKRVDILVCNAGVGLMGPLEAQSYETMTRIFDVNLFGTIRS
IQAFLPGMKARRSGRILVTGSLGGLQGLPFNEVYCASKFAVEGVCESLAILLQQFNVQIA
HLTTVFLCGAGEKDVSELPLSAITLIYYYNDAAQDTADIVKVFLDVIRADSPALRYYTST
ALMPLSTLKLALQDGSQYVRTMSKIIFSANQTEDA
>U2FXX4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Salinisphaera shabanensis E1L3A|TrEMBL
MAMTQAVLPQFRAQGAGTIVNITSSVTFKALPLVSMYTASKAAVNAFTASLAIELAPFGI
NVRIVLPDRSLKTRFSANAKRAGLDNADYADMIQQTVTQMTDESGPVTNAADVAEAVWRA
ATDPTAPIRIPAGADAIEWAQEAGLWA
>A0A7R8H0E2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Lepeophtheirus salmonis|TrEMBL
MTKHASQAMKRAQKAGSIVNISSVVGKTGNVGQTNYSASKGGVISFTKSAAKELAKFHIR
VNCICPGFIDTPMTKDLPEHVKYLLDSQNRWVLFAIPLGCYGEPEDIAETVAFLASSKAK
YITGTSVDVNGGML
>A0A8C5FGD0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Gadus morhua|TrEMBL
MEKKVVLITGCSSGIGLSLAVRLASDPDKTYKVYATMRNLAKKERLLGCVKDLHKDTLDI
LQMDVTNHQSILEARDRVVEKRVDILVCNAGVGLIGPLEAQGLDTMRQILEVNLLGTIQT
IQAFLPDMKARCKGHILVTGSIGGLHGLPFNEVYCASKFAIEGACESLAIILQHFNIHMS
LIECGPVNTDFLDNQEKAELGDASLGQVDASTLSLYGQYLHHCTTMFQNAAQDTEDIVKV
FLGAIQASRPSFRYYTSGAMPPLVRLKTSFPEGCRFIRAISHPYFILPTVGLAGFQGSGS
CVSNSEVAEQTGPACPGEIHSYT
>A0A5E6MML5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Methylacidimicrobium tartarophylax|TrEMBL
MVRQSFLGCSAWITGASSGLGAEFARQLAPEAGCLVLTARREERLRELAEEIRKNHPKAQ
IIVAPADLAAPEGIEAVIDRLETERVEVDLLVNNAGVGDFGLFYRADLRRLRDMLDLNVR
GFTLLLWWLLPRMIRRGKGCIINIGSISGLRPLPYYSAYAATKAYVHSLSHGLEWELAGT
GVTLTQVCPAAVATEFFERAVRCPEDLKEVGGPPFMWTSPEEVVRCSLEAASRGKSQVTP
GFVPRLCAAIFSYVPLPLLRIVYRAALSGKRRPGGELADERIFMEKRSDGRPL
>A0A2K6UYM0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Saimiri boliviensis boliviensis|TrEMBL
MTRTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATMRDLKTQGQLWEAARAQGCPRDSL
ETLQLDVRDSKSVADAQARVTEGRVDILVCNAGQGLLGPLEALGEDAVGSVLDVNVAGTV
RMLQAFLPEMKRRGSGRVLVTGSMGGLMGLPFNDVYCASKFALEGLCESLAVLLPPFGVH
VSLIECGPVHTPFMQKVLGGPGGMLDRTDTRTRLLFHQYLQHNKEIFREAAQHPEEVVEV
FLTALRAPKPALRYFTTERFLPLQQMRLDDPSGSSYVAAMHRNVFPKEPAEAEAGAGAGA
GGVGDPELGDPPAAPQ
>A0A3P8NJ60|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Astatotilapia calliptera|TrEMBL
MKLYQQGHEKKIEGLQLADNGQMFSLKCPCDSVRCKNSFNMPPFYSVAHFAVSSSLCSTG
SFNVGELGSMDKKVVLITGCSSGIGLSLAVRLASDPDKTFKVYATMRNLSKKERLLESVK
GLHRDTLDILQMDVTDRQSILDARDRIVEKRINILVCNAGVGLMGPLEVQSLNSMRHILE
VNLLGTIQTIQAFLPQMKAQSQGRILVTGSTGGLHGLPFNEVYCASKFAIEGACESLAIL
LKHFNIHVSLIECGPVNTDFLVNLKKTELGDTSLQQVDTQTQRLYEKYLQHCRSVFQNAA
QDTEDIVKVFLDAIQSPSPAFRYFTSTTGPPVTQLKVTEPDDSYISAMSKIIFSPEEQ
>W6W630|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhizobium sp. (strain CF080)|TrEMBL
MSNSLSKGTALITGASSGIGAIYAERLARRGHDLILVARSRDKLDTLARRITDETGRSVE
VIPADLSDKADLARIEEVLRNDRSIGVLVNNAGLGATAPLLSSDIGKMDEMLTLNVNALM
RLTYAAAPGFVARGTGTIINISSIVAIGPEVLNGVYGGSKAFVLAFSQSLHHELSAKGVT
VQAVLPGATATDFWGTAGTPLEHLPSQIVMRAEDLVDAALAGLDQGELVTIPALPDLADW
QAYEAARQKMLPNLSRSLPADRYKVA
>H0T0S3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bradyrhizobium sp. STM 3809|TrEMBL
MDQTTQPRTVGHLRPVADNIWIVDAGRIRAAGLPLPVRMTVIRLASGDLLLHSPTRFSDG
LREELERLGPIRYLLAPNVAHWMFLPDWQAALPIARVYAAPGLSERQRVRRSGLRIDREL
TDVTPDEWSEDLQLVLITAPLFSEVAVFHRPTRTLILTDLVQNLSPEGLGVLPRAAARLL
GMTAPDGKAPAFLRWLLRLGGRAVQLAAARLIALAPERVIFAHGRWFEAGGTTQLRRALG
WLLDGSPEARRLIQDLKGTRVVVTGASSGIGRATALALAREGASLALAARRETVLKDLAA
ECETLGARAIAVGTDVTDADAVKRLAEQAVQSFGGIDVWINNAGTGVFGAYQDADLALHR
KTIEVNLLGTMNGAYAVLPLFLRQRRGTLINNISLGGWAPTPFAAAYTASKFGLRGFSAS
LRQELAAHKDIHVCSVFPAMVDTPGFVHGANMSGRTLDPGPLLYRPEDVAETFVQLIHAP
RDEVAVGWPARLGQVSYALARWPTERLMSTAVRFLLARAKGAPRSQGAVLAPIAAGTAVS
GGWLGRKKLPPAGQLSKIGLAVGVGGLALLLIARGRGRQPAPRARARR
>A0A4W2H9C5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bos indicus x Bos taurus|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSQSFKVYATLRDLASQGPLLEAAQSRGCLPGSL
ETLQLDVRDADSIAAAQARVTEGRVDVLVCNAGRGLVGPLEAHKEGSVDAVLDVNLTGTV
RMLQAFLPDMKRRRSGRILVTGSIGGLMALPFNAVYCASKFALEGLCESLAILLQPFGVH
VSLIECGPVHTPFPEKVEGGLGGMLDRADVETRDLFNRYRRHCERVIREAGQDPEEVVEV
FLQALRAPRPALRYFTTERFLPLVQLRFSDPSGSSYVAAAHKSAFHDKAAEGSDGAGAET
EAGKLEASELRAPLAPQ
>Q5M8H2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xenopus tropicalis|TrEMBL
MHVLLEIVWLLLVIVYSYLESFVKLFIPLKRKSVKGEVVLITGAGHGIGKITAQIFGELE
SVLVLWDINKQGVEETAEKCRKGGAKVYTYVVDCSKREEINTAANKVKQEVGDVTILINN
AGIIFCADVLTLQDQQIEKIFEVNILAHFWTTRAFLPSMLRNNHGHIVTVASSAGFVGVQ
FMVDYCSTKFAALGYHKALTAELLALGKSGIKTSCLCPVFVDTGFVKNPSLRLAPVLQPE
EVAQTLVDGILINKKMICVPSSVSLVPVLAFFLPERALNALNEFQNLKFEAKVHSRDKDK
>A0A086M5J3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii RUB|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALVRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKAMAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>H2NU01|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pongo abelii|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSNSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAMASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNEVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDDPAKAEAGGGAGP
GAGAEAGPSGVGDPELGDPPAARQ
>A0A086L1A1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii FOU|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALVRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKAMAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>W6RJ28|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhizobium favelukesii|TrEMBL
MDKQVIVITGASSGFGALTARTLAAEGHVVYAGIRDTAGRNAKAVADIAAFSRENNVDLR
SVELDVVSNASVEAGIAKVIAEVGQLDVVIHNAGHMSFGPAEAFTPEQYAELFDVNVLST
QRVNRAALPHMRKRGKGLVVWVSSSSTRGGTPPYLAPYFAAKAAMDSVAVSYASELARWG
IETAIIVPGAFTRGTNHFAHSGSPADAARAAEYNDGPYRGVPEQALQGLAALEPADADAG
SVATSIAQVVAMPFGKRPFRTHVDPSEDGAEVVNGVADRVRAEMFRRIGLEDLLKPVIR
>A0A2P6R637|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rosa chinensis|TrEMBL
MASSSVSSSVIPPKEKYDVFLSFRGADTRQTFTSHLLAALIRWKVKTFIDYGLERGDEVG
PALLKAIKESRISVIIFSKDYASSAWCFEELACILECMEKHGQYVIPIFYEIEPSQVRYQ
TGSYETAFAQHEQWLKDDKTDKVAKWKEALVKAAGLSGSDSTSKNFGMIPL
>A0A3P9NY80|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Poecilia reticulata|TrEMBL
MSMEKKVVLITGCSSGIGLSLAVRLASDTSKVFKVYATMRNLAKKERLLECVKDLHRDTL
EILQMDVTDRQSILXARDKVVEKRVDILVCNAGVGLMGPLEVQSLDTMRRILEVNLLGTI
QTIQVFLSGMKAQGQGRILVTGSTGGLHGLPFNEVYCASKFAVEGACESLAVLLQHFNIQ
VSLIECGPVNSDFLINLQKAELGDPSLQQVDGRTISLYEKYLQHCSTVFQNAAQDTEDIV
EVFLDAIHSTSPAFRYFTNSVMPPLTQLKVTEPHGREYIETMSKIIFADEDQ
>M3WFH9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Felis catus|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSRRFKVYATLRDLRAQGPLREAAQSRGCPPGSL
EMLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLEVQEAGAVGSVLDVNVAGTV
RTLQAFLPDMKRRRSGRVLVTGSMGGLMGLPFNAVYCASKFAIEGLCESLAVLLPPFGVH
VSLIECGPVRTAFQEKLEGGPGGALDGADAETRDLFSRYQRHLERIFHEAAQDPEEVTEV
FLAALRAPRPALRYFSTERFLPLVRMRVTDPSGRSYVAAMHRAVFADEPAEESAADLGGP
ALGAPPAAPQ
>A0A2K5DSV0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Aotus nancymaae|TrEMBL
MVRTVVLITSCSLGISLHLVRSRHLYATMRDLKTQGQLWEAARAQGCPLDSLETLQLDVR
DSKSVADAQGCVTEGRVDILVCNAGQGLLGPLEALGEDAVGSVLDVNVAGTVRMLQAFLP
EMKRRGSGRVLVTGSMGGLMGDLGNLVSPNHQGLPFNDVYCASKFALEGLCESLAVLLPP
FGVHVSLIECGPVHTPFMQKVLGGPGGMLDRTDTRTRLLFHQYLQHNKEIFREAAQHPEE
VVEVFLTALRAPKPALRYFTTERFLPLQQMRLDDPSGSSYVAAMHRNVFPREPAEAEAGA
GAGASGVGDPELGDPLAAPQ
>A0A8C3HS64|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Chrysemys picta bellii|TrEMBL
MEKTVVLITGCSSGIGLGLAVRLASDASRRFKVYATMRNLAKKERLLECVRGCHASTLEI
LQLDVTDPLSLAAAAQQVQEQRVDVLVCNAGVGLMGPLETCSFQAMKTIFDVNVFGTIGT
IQAFLPGMKRRKAGKIIISSSVGALQGIPFNAVYCASKFAVEGLCESLAVILQQFNVHVT
LIECGPVNTSFLANLQRTDAEGSALQGLDPQTRALYSQYLQHCQSLFRDVAQDTEEVLQV
FLEAICAPCPPLRSFTTQFFMPLTRLKLTSPDGSEYVRAMHKFVFSLTSAKHAAVSSAPS
EPPGLCAPTWETPPQVAAGGWCCRHRSPHWARPPSLVQGTGVERGGAEGCISFLLRA
>D7UVA9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Listeria grayi DSM 20601|TrEMBL
MEQVIVITGASSGFGALTARALANAGHIVYAGIRETTGRNAVKVKELEAFAETSGVKISA
LEMDVLSQTSVDNAIAQVEKERGQIDVIIHNAGHMVSGAAEAFTPEQLAQLYDVNVLSTQ
RVNRAALPGMRKRQAGLILWVSSSSVKGGTPPFLSPYFAAKAGMDSLAVSYAGELAQFGI
ETSIIVPGAFTKGTNHFANSGHPADTKIQAEYDAKYPDLMENIGKKLAEIEPADADPSSV
AAEIIRIISLPAGERPYRVHVDPTDDGSKAVSDIADQNRIGFLNRIGLADFLKTIIQDN
>S8F1P4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii (strain ATCC 50611 / Me49)|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALMRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKAMAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>Q397S0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MNKNPKVWLVTGASSGFGKALAEAVIANGDSIAITARRLDRLQAIAQGHEDRVLPLAVDV
TDAAARDKAVADTLARFGRIDVLANVAGRGVAGACEEFSLDQLREQMELNFFAAAEMTRA
VLPQMRVQGSGHVLTVSSIAGLVSMNAAGPYCAAKFAIEGWTEALAIEARPLGIHVTLVE
PGAFRTEFAGDVNMRPVQRIDAYRPVVEPFEAYLEHSAGKQMGDPAKAARRMLEVVASDA
PPVRLMLGRDAFSIWDATIAKRIQDIDSWRASGEDTAFDGAELEEIRL
>A0A139Y721|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii ARI|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALVRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKAMAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>A0A1Z5KSE2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Fistulifera solaris|TrEMBL
MPKHNFQPPGAFLQEINSLIHQEPFESILYCVYWSVVIGVCSPIAILLLQLRLLFRLLGW
ILDSVRKYSACDPKGHPTRESAVVITGCDTGFGRDVALRAAEAGYIVFAGCLKEESVTER
NQLSNNIKAFTMNVTNDEHVEKAAQMVSRWLDETTTQQRILHALINMAGVGFCGNVDFMP
LNLFQTSMDVNFFGTVRCCKAFLPIFKSQATSNTYNDARILNIVSMAGLVPTSVGTSAYA
ASKYAVQGFSTAFRLEAMGFGIQVATINPSFHETNIVTGLSTQVEKLCADLPGAKREEYG
EEFLEWLLTQTRIPLLVSWRAENVVQQTMNCLMNRSIPSEVVVGSDAKFVLVTLRIFPAW
FRDILFRIDSLRYAVPASMRRMKAKSD
>A0A378KH90|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella donaldsonii|TrEMBL
MTNINNNKAALVTGASHGIGLELAKILLGDGWVVYGTGRDVSSLEDTKALFPRFVPIQSD
FTRNSDIEQVAKIINDSGISLHLLVQNAGMKSPPRPLTEYDCDSIDEVFQVNLLAPMKLT
ALLAVRMPEKARILFVTSRAATLKLKESSTYCASKAGLDEVTAIVRKELAEKNIGVSCVI
PGEVDTRIQKILRETTSFHLHKMFDEAYQSGQLISPETCAEFLKWFLCDLSFDEFKQSNM
PVSIYEEWHHPFWLKDRNQLPPFPF
>A0A8C7WRH1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Oryzias sinensis|TrEMBL
MEKKVVLITGCSSGIGLSLAVRLASDPAKTFKVYATMRNLAKKERLLECVKGLHRDTLEI
LQMDVTDQKSILDAKERVVEKRVDILVCNAGLGLMGPLEVQSLNSMRHILEVNLLGTIQT
IQAFLAGMKAQGQGHILVTGSTGGLHGLPFNELYCASKFAIEGACESLAILLQHFNINMS
LIECGPVNTDFLVNLQKAELEDMSVEQVDGKTLSLYEKYLRHCNSVFQNAAQDTEDIVKI
FLTAIQSPSPAFRYFTNSVVEPPLIKLKAAQPDGVQYIKAMSEIVFSGEEQ
>A0A7R8D623|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Lepeophtheirus salmonis|TrEMBL
MGQWALVTGATDGIGRAYADALAKRGLDIILVSRSPFKLQNAAADIENKYKVKTKIIDVD
FTTDSLELASRLKRELKELEVGVLINNVGMSYEYPEEFLSMSEGESATDTFIKCNIMSVD
IMTRLLLPSMVDRKKGVIVNIASLSGQYTSPFLSLYSATKAYVDFFTRGLEAEYRSKGIT
IQCVLPGFVASKMSKIRRPNVFAPSPEMFVKSCMKKLGVQSRTNGYWLHEVMSCALDLLP
EWMVQKIFFGVLNATRLKALKKKRR
>A0A2K6CPL7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Macaca nemestrina|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARARGCPLGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEAVGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVTEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVAAMHRHVFGDDPAEAEAGAGPGA
GAGPSEVGDPELGDPPAAPQ
>K9PZ07|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Leptolyngbya sp. PCC 7376|TrEMBL
MANQVVLVTGASAGIGKATAKTLLAEGYTVYVAARRVGKMKDLEELGVIAIQMDITKETE
VAAAVEQITAENNGVDILVNNAGFGLYGAMEDISIDEARYQFEVNLFGLARLTQLVLPYM
RSQKSGKIINISSIGGKIYTPLGSWYYATKHALEGWSDCLRFELKAFNIDVVIIEPGLIQ
TEFGNVMIAPMMRRSGRGVYGNLAKTLARSSIDMYANNSASKPQVVADLILKAIKAKKPK
TRYVGGKLATPLLFARKWGGDRLFDWLIGNMLK
>E3TEC1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ictalurus punctatus|TrEMBL
MEAADILKQVKVLLFWVGAVTVAWVSLCTLYRLFNGLRVWVLGNGNLIKASKLGKWAVIT
GATDGIGKAYAEELARRGFAIVLISRTQEKPDDVSKAIESKYNVETKTISADFGSVDIYS
KIESGLAGLEIGILVNNVGVSYSYPEFFLNIPNLDNFVNNMININVTSVCQMTRLVLPRM
VDRSKGVILNIASASGMYPVPLLTLYSSSKAFVNFFSRGLDAEYRSKGIIIQSVLPFYVT
TKLSKIKRASLDIPTPETYVASQLSTVSLQSQTNGYLPHAIMGWVTTSLLPAQLLTKYVM
NMGLSQRARYLKKQKQG
>A0A672RUC2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sinocyclocheilus grahami|TrEMBL
MEQKVVLITGCSSGIGLSLAVHLASNPSKAYKVYATMRNLDKKQRLMESVRELHKDTMAI
LQMDVTDQQSILDAKRNITEGRIDILVCNAGVGLMGPLEAHSLDTIHAILDVNLLGTLRT
IQTFLPDMKKKRHGRILVTGSMGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLMNLKRTEPSEEALEVDAHTRSLYDQYLQHCQSVFQNAAQDTDDIIQVY
MEAIEAQAPFLRYYTNRALLPMSSLKLTSMDGSQYIRAMSKLIFSAPNTDPQI
>C1L7P2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Schistosoma japonicum|TrEMBL
MRTSTDDMATSSTPHFIKHNFFILTITLIIIWFTFKLLQLLKICLVYTVAKWCFSKRKSL
RKAGEWAIVTGASSGIGEAYAEELAKDGLNILLISNDESQLRLVSERLSTDYHVETRIVV
ADFTQNNVYDVIRPAIQQLSTIACLVNNVGMGLPIGPFVGGTQSPNEQSIHDIIHCNVLS
TAMMTQIVLPKMLSQKGSNPGIINIGSFTGLKVLPYASMYAATKAFIIQLSRCISAEKYS
RDVIVQTICPLVVSTKLSFCKPTSFFVPTAQVFAKSALDMFGVQQQTTGYMRHEFKGFLY
TLMPTSLWVKFLQICFVPSMKESTKSE
>A0A822ING6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Methanosarcinales archaeon|TrEMBL
MEVEIYMKNSRMNNDFKEKKTALITGASSGIGYEFSKLFAEAGYNLVLVARNKQKLKQLA
DELEGKFGTSVMSISKDLSASTAPQEIFDGLQQESIHIDILVNNAGFNVYGSFSETDLME
ELQMVQVNLVSLTHLTKLFLPGMLIKGYGKILNVGSTGSFGPGPFNAVYCATKSFVLSFS
EAIAEELQGTGITVTALCPGATKTEFFKRANMANINLLKRGVMDAKTVAEIGYNSVMKGE
NVVIAGTYNKLMIFLTRFMPRDMITKMVKDMMSVGKNNYQ
>A0A2K5QW76|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cebus imitator|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATMRDLKTQGQLWEAARAQGCPQDSL
EMLQLDVRDSKSVADAQACVTEGRVDILVCNAGQGLLGPLEALGEDAVGSVLDVNVAGTV
RMLQAFLPEMKRRGSGRVLVTGSMGGLMGLPFNDVYCASKFALEGLCESLAVLLPPFGVH
SVSLIECGPVHTPFMQKVLGGPGGMLDRTDTRTRLLFHQYLQHNKEIFREAAQRPEEVVE
VFLTALRAAKPALRYFTTERFLPLQQMRLDNPSGSSYVAAMHRNVFPKEPSETEAGTGTS
GVGDPELGDPLAAPQ
>F8GWB4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cupriavidus necator (strain ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453 / N-1)|TrEMBL
MRSLIKQASSVKLNCRHLNSRIQKGTAVSNSKVVVITGVSSGIGRATAAKFAQQGYRVFG
TVRNSAKAQPISGVELVEMDIRDEASVQHGIQAIIAHAKRIDVLVNSAGVTLLGSTEETS
IAEAQSLFDTNVFGILRTTQAVLPHMRAQRSGRIVNISSVLGFLPAPYMGLYSASKHAVE
GMSETLDHEVRKFGIRVVLVEPSFTKTGLDTNAPHAASKISAYDDERNIVLQAIQKNVKD
APDPDGVATTIVDAAVGAWGMRRPPKGQAYLLSKLRRFMPAGPVDASLRKTFGLS
>A0A060RKT4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Streptococcus gallolyticus|TrEMBL
MTKTWFITGTSTGFGKELARLLAQKDDVNLVATARKPEQLSYLDEFDHGQILKLKLDVTN
QEEIQKAVKATLDTFGRIDVLVNNAGIGYFGTFEESNRETVQYMFDVNVWGLVDMTRAVL
PTMRKQNEGVIINFSSIGGLYSFPTLSFYHGTKYAVEGLSESLAKEVAHKNIQVLIIEPS
GFRTDWAGRSSDKALPSLEDYQQFTDFITTNENSAGHEAGDPIKAAEIIYDQVTNNPQLP
LRLPLGAFATDIAIDKYSKQLAEFKELHDLSASADVPEN
>A0A8C8TC16|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Peromyscus maniculatus bairdii|TrEMBL
MDRTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATMRDLKAQGPLLEAARARGCPPGSL
ETLELDVRDSDSVAAAQACVSEGRVDVLVCNAGRGLFGPLEAHELDAVGAVLDVNVVGTV
RMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAILLPLFGVH
VSLIECGPVHTAFYEKLEGGPGGALERADAQTRRLFTHYQRGYEQALSEAQDPEEVTELF
LTALRAPRPALRYFSTDRFLPLTRMRTEDPSGSSYVAAMHREAFADLQAQEGPEAGARAP
GDRDATSSALICLPGCTSPRVASELCWPASNKPGQDPCYQQKS
>A0A0S4U167|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ralstonia solanacearum|TrEMBL
MSNSKVVVITGVSSGIGRATAAKFALRGCRVFGTVRNLARTQPIAGVELVQMDIRDEASV
QQGIETIIRQAERIDVLVNSAGVALLGATEETSVAEAQALFDTNVFGILRTTRAVLPHMR
AQRSGRIINISSVLGFLPAPYMGLYSASKHAVEGMSETLDHEVRKFGIRVALVEPSFTKT
SLDTNAPHAASKVSAYDTERGVVSQAIQKNVQKAPAPDSVAGTIVDAALGAWKMRRTPKG
EASLLSRLRRFMPAGPVDSGLRKTFGLS
>A0A378KLD1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella gratiana|TrEMBL
MMNTKALFPRFVPIQSDFTRNSDIEQVAKIINESDIPLHLLVHNAGMKSPPRPLTEYDCD
SIDAVFQVNLLAPMKLTALLAVGMPEKSRILFVTSRAATLKLKESSTYCASKAGLDEVTA
IVRKELAEKNIGVFCVIPGEVDTRIQKILRETTSFHLHKMFDEAYQSGHLISPETCGEFL
KWILCGLSFDEFKQSNMPVSIYEEWHHPFWLRDKSQLPPFPF
>I3M2M3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ictidomys tridecemlineatus|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSQSFKVYATMRDLRAQGQLWKAARARGCPSDSL
ETLELDVRDSDSVAAARARVTEGRVDVLVCNAGRGLLGPLESHGLDAVGSVLDVNVVGTV
RTLQAFLPDMKRRCSGRIMVTGSVGGLMGLPFNAVYCASKFALEGLCESLAVLLLPFGVH
VSLIECGPVHTAFYEKLEGGPGGTLSHTDAQTRHLFSLYQRHCEQIIREAQDPEEVTEVF
LTALRAPKPSLRYYSTERFLPLSRLRLEDPSGCSYVTAMHHAVFADQPAEAAGTREPGDP
ELGASPAAPK
>A0A8C2ZT64|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cyclopterus lumpus|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPDKAFKVYATMRNLAKKERLLECVKSLHKDTLDI
LQMDVTVRQSIQNARDRVTEKRVDILVCNAGVGLTGPLEVQSLDSMRKILEVNLFGTIQT
IQAFLPDMKAQGQGRILVTGSTGGLQGLPFNEVYCASKFAIEGACESLAVLLQHFNIHVT
LIECGPVNTDFLVNLQRAELGDASLQQVDALTLSLYEKYLQHCGSVFQNAAQDTEDIVKV
FLEAIQSASPAFRYFTGGGVPPLTKLKITDPDGSRYISALSKIMFSAEEQ
>A0A6J8AXP3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sea mussel|TrEMBL
MERWAGRVALVTGASVGIGAAIVRQLVQNGMKVVGCSRNIEKIEALKTELSSAKGQVVPV
RCDLKNEQDIMDMFTMIKRDLGGVDVCVNNAGLAHAAPLLSGETKDWREMVDVNIIGLTI
CTREAVKQMREKGANDGHVFLLNSMSGHRVIPSPNGHFYSATKFAVTALGDGIRNELREM
KSQIRITSISPGLVETEFAYRMQKNDDKAKALYESIKCLQADDIADALVYALGAPAHAQI
HDILIRPTDQVS
>A0A6J8AXP3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mytilus coruscus|TrEMBL
MERWAGRVALVTGASVGIGAAIVRQLVQNGMKVVGCSRNIEKIEALKTELSSAKGQVVPV
RCDLKNEQDIMDMFTMIKRDLGGVDVCVNNAGLAHAAPLLSGETKDWREMVDVNIIGLTI
CTREAVKQMREKGANDGHVFLLNSMSGHRVIPSPNGHFYSATKFAVTALGDGIRNELREM
KSQIRITSISPGLVETEFAYRMQKNDDKAKALYESIKCLQADDIADALVYALGAPAHAQI
HDILIRPTDQVS
>A0A8C5YYV0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Marmota marmota marmota|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSRSFKVYATLRDLRAQGQLWKAARARGCPSDSL
ETLELDVRDSDSVAAARARVTEGRVDVLVCNAGRGLLGPLEAHGLGAVGSVLDVNVVGTL
RTLQAFLPDMKRRRSGRILVTGSVGGLMGLPFNAVYCASKFALEGLCESLAVLLLPFGVH
VSLIECGPVHTAFYEKLEGGPGGALNHTDAQTRHLFSLYQRHCEQIIREAQDPEEVTEVF
LTALRAPKPSLRYYSTERFLPLSRLRLEDPSGCSYVTAMHRAVFADQPAEAAGTRESEDP
ELGASPAAPK
>B6AG99|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cryptosporidium muris (strain RN66)|TrEMBL
MISNIFTLIGQISIFQYVYALFTSLYTSAFRSSKKPRDFGKWAIVTGATDGIGKAMAIEL
YKHGLNLMIIGRNKGKLSNTALEMRNLQIYPEPEIKEVVMDFSDPSGYDQLNEEIKKLDD
IGILVNNAGVGYPYPQYFDELDVSLINEIIDVNIRGVFMMTKMVYGKMKEQRRGAILCIG
SGFSELTSAPLYSIYASSKKAIQNFCNNLQIESSAYNIVVQCQILFIVMTKLSKMKKETL
FVIPPQKMAQESIRELCKGGLIWSTICPYWAHKLQLIFANLIPTFIWNSLILWKLRSIRD
RALKKKVA
>U5RY96|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Clostridium autoethanogenum DSM 10061|TrEMBL
MKNEIVVLITGCSTGIGRELCNILSHKGCTVVATARNVEALKDLSAFLKLPLDVTKKESI
HSTINQVISKFHKIDILINNAGYSLRGALEEIDVNSSKSMFDVNVFGIINMVQEVIPEMR
KKQSGKIINIGSISGKFVQSINGVYCASKFAVEALSDTLRLELHSYNIQTTVIEPGPMKT
HFFNTLVDNSGDLMGNSQSCYSHFYKSDDKYRKKQKQADPKEAAQAISNIILKKRINARY
KVTVPFIYSMVTYFPDFLREYFMKKR
>A0A452QT03|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ursus americanus|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSRSFKVYATLRDLGAQGPLWEAARSRGCPPDSL
ETLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLEMHAAGTVGSVLDVNVAGTV
RTLQAFLPDMKRRRSGRVLVTGSMGGLMGLPFNAVYCASKFAIEGLCESLAVLLPPFGVH
VSLIECGPVRTAFLEKLESVPGGALDGADAETRDLFSRYQRHLERIFREAAQDPEEVTEV
FLAALRAPRPALRYFSTESFLPLAHLRLADPSGCSYVAAMHRAVFADEPAEEESAAAPGG
PELRAPPAAAPQ
>Q1WNP3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Macaca mulatta|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQCRLWEAARARGCPLGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEAVGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVTEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVAAMHRHVFGDDPAEAEAGAGPGA
GAGPSEVGDPELGDPPAAPQ
>A0A083ZAC3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhizobium radiobacter|TrEMBL
MKTVLISGSGSGMGLLTAQTLIRQGYAVYAGVRDPHGRSAGRREALERYATEHGGYVRVI
DMDIHSEESCQAAVDQLVADHGHLDVVIHNAAHLFIGVFEGFTPDQLTDCLNTNVVGAHR
LNRAAIPQMRKQGNGVLLYVGSTISRIVTPFVGPYIAGKYALDALAEVTAYEINRFGIET
VIVMPGIFPDGTAHFESAVHPGDDDAVEGYEKFKADFDNIGPGLRALLRGADAPIQGVAD
EIARVLALPKGDKPMRTIIDYSDYGTPVINAVVETQTARVFQMMGYEHLLKVS
>B7QMN2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MAAGKVDTGTSVARTLGGGDRSGAGIGKAICGALAEKGARLIVADINLAAAEAVANALTG
ASDDQKHVGMHVDTADSSSVQALFAAISEVCGKPASILVNCAGILLPYTSIVDTNEDAFD
RVLSINLKGTFLMTQAATRDMLAGGVTDGAVVNISSIVAKTCGGLCSYVASKAAIVGLTK
AVAAELADRGIRCNAVLPGATHNPDRRGFFTEEAWRRILASVPLGRKAQPREVADVVAFL
CSPQSSYMTGAAVEVAGGWDM
>B7QBJ7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MMVENMTIFVAFLAIVTVFSMDNSEAHANKGDKNEPDGSPSQAECQSLGLSGRLGVVTGG
ASGIGRSVCMVLAREGATVIVADRNRTGSDETLQMLQGSYPGDHRVIYVDVSNSTAVDVL
FEEIATYFPERKISVVVNSAGIVEAAAPIQDMNDTQLDDTLATNLRGTFLIDRASVKHML
ANNVTDGAIVNIASIIAKTAFPRYTPYSASKGGVVSLTKAVALEVASSGIRVNAMLPGPV
DTPLLARLPPEVSSAFIAATAFKRKARPDEISETIAFMCSPKSSFLTGAAIDVTGGIIA
>B7P1Q5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MASFKGDHRAIYVDVSNSTAVSNLFEEIESSFSGRKISVVVNTAGISGMLAPIEETNDTA
YDDVIATNLRVRPSKPVNGVLDSE
>A0A3B3CUQ5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Oryzias melastigma|TrEMBL
MEKKVVLITGCSSGIGLSLAVRLASDPAKTFKVYATMRNLAKKERLLEFVKELHRDTLEI
LQMDVTDQQSILDAKEKVVEKRVDILVCNAGLGLMGPLEVQSLDSMRQILEVNLLGTIQT
IQAFLAGMKAQGQGHILVTGSTGGLHGLPFNELYCASKFAIEGACESLAILLQHFNINMS
LIECGPVNTDFLVNLQKAELEDLSVQQVDAKTFSLYEKYLQHCNSVFQNAAQDTEDIVKI
FLTAIQSPSPAFRYFTNSVVEPPLTKLKAAQPDGIQYIKAMSKIVFSGEEK
>Q395P1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MTQAHRGTALITGASSGIGAVYADRLARRGYDLILVARNRDRLVALAERITNETRRSVEI
IGADLNDRAALATVEAKLKQDASITLLVNNAGIGTHAPLLDSDVDAMTRMIDLNVTALTR
LTYAAVPGFVARGRGSVINISSIVAISPETLNGVYGGSKAFVLAFSQSLHHELAGKGVQV
QAVLPGATATDFWQTGGLPLEHLPKEIVMSANDMVDAALVGFDRGELVTIPSLHAGDEWT
AYEAARRTMAPHLSADTPAPRYATAG
>Q9VDC0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MNRWLNRVAVVTGASAGIGAACCRDLVAKGMVVVGLARREKVLQDIKSSLPADQAARFHT
RPCDVSNEQQVIDTFAWIDRTLGGADVLVNNAGIIRQMNITDPENSADVRAILDVNVLGV
TWCTRQWFLSLQRRKVNDGHVVVINSVVGHSVPAVEGFSLNMYAPSKHAITALTEILRQE
FIKKGTQTKITSISPGVVATEIFEAGSWEQPTGMPMLRSEDIADAVTYCIQTPPTVQIKE
LIIKPVGEGF
>W5LEN1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Astyanax mexicanus|TrEMBL
MRHNRDQLSSASHLHPDHSCSHPQACLHLTVLHAAILWTEISAALLMEQKVVLITGCSSG
IGLSLAVHLASDPSKAYKVYATMRNLDKKQRLMESVRGLHKDTMAILQMDITDQQSILNA
QSNITEGRVDILVCNAGVGLMGPLEAQSDETMRRILDVNLLGTIHTIQTFLPDMKRRKDG
RILVTGSMGGLQGLPFNEVYCASKFAIEGACESLAILLQNFNIHVSMIECGPVNTDFLKN
LMKTEPTDESVEVDADTRSLYKKYLQHCQEIFQNAAQDTEEIVQVFLEVIQSPCPLFRYY
TNTALLPLSSLKLMALDGSQYIRAMGKFIFSAEHADSRK
>A0A2K6RWW5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhinopithecus roxellana|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARAWGCPLGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEAVGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREAAQTPEEVVEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVAAMHRHVFGDDPAEAEAGAGTGG
GAGPSGVGDPELGDPPAAPH
>F7QKA0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bradyrhizobiaceae bacterium SG-6C|TrEMBL
MTAERKSGQCALVTGASGGIGLELARVLAANGFDLVLLARSAAKLQEIANELKANHGSKV
TVLPADLSDPGTPQAVFNTLADAGIRIDLLVNNAGLLFEDRFNAISLDDTMQLLRVNIGA
TTAMTHLFLGSMLERNSGRILNVASIAGFVPVPNLAVYAASKAYVLSFGEALSQELSGSK
VTLTTLCPGVTETAMVHGTNLASVPKMMIMDAKTVAREGYRACMSGKPVHVAGIANEMAV
QWIKYQPSWLMRAVGGFLSRNRNS
>A0A068QP71|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Xenorhabdus doucetiae|TrEMBL
MMFNEVNGSSALQGKRVVVTGGGRDFGQAVSVWLAREGAQVDLCARQLAGAEATCEIIRR
EGGIARSYQCDMSDAQSVSDFATQLLQDNQPIDILILSAAQWLEGYLGEGDSEADIVSTV
NSGITGSILLTKALLPSLRQSQGADIVAMVSVCGIPQFTESVAHPAFFAAKHAMSGFSQN
LAHHLSKENIRVTGLYPPDFQLNGFDEKLDDHKKMGEQMLNGRSVWETLRFVITQPRSCH
IKAIYFQGPTFKDFE
>F4CC35|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sphingobacterium sp. (strain 21)|TrEMBL
MTQQKDKVWFITGTSRGFGRVWAEAALARGDKVAATARKLESIADLKDKYGEQVLTVALD
VTKPDQVKEAVTAAHAHFGRLDIVLNNAGYSLVGTIEEASPADIRALYETNILGPVAVIQ
AALPLLREQGYGHILGTSSNLGHVTMPVIGYYCSSKWAFEAIHESLAAEVAPFGIQVTII
EPGAYATEFGSQESLKFAQGMEVYTDFKAKFVDSLKTMERGDPAATPQALFKMIDAEQPP
LRFNLGSHNLSGTRAAYAQRLAIWEAWDEVSRAAQGEPK
>A0A099KZD9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Colwellia psychrerythraea|TrEMBL
MAKVVLITGASSGIGRITAILLAQHGYIVYAGTRKPSKFTIKLDNLHVLALDITDSQSIK
HTIDLIQADHGRIDVLINNAGYALVSTVEQASEEEMFNQFNINVFSILRLCKAVTPLMRV
NSSGVIINISSFLGKVGLPLFTFYNASKYAVEGITDSLRYELEPFNIRVHSIMPGFFNTD
FAKGNLITNDAIHDKSSPYCELASNLLPDILAQINGGNAAKEAAELIFKVIKDDASPART
TVGDKASKFIAMRRELSDEDFERRVREYYKLNG
>A0A5B6ZMP0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Davidia involucrata|TrEMBL
MAMELQGPVLIAIVGTLGFITVCRLIVNIFMWVWVMFLRPPKNLKECYGSWAVVTGCTDG
IGKALALELASKGLNLVLVGRNPSKLEVTSNEILARNGTVEVKTIIIDFAKLSREEIAKR
IEEGIEGLGVGVLINNMGLAYPHAGFLHEVDSEMLESVIRVNVQGTTWVTRSVLPGMLKK
KRGAIVNMGAGGTVVFSSFPLYTLYAATKAYITMFSKSISLEYKKHGIDIQCQMPLFIAT
KMTAIERSSFFIPSPETYSKASLRVIGYEQVCMPYWPHYVQWCILSALPDALVDWCLLQV
FLGRATQGFSIAKCITVLVFFSGDSWYPKEGFHLAGDRKHDLMLHSSSNPATFK
>A0A653MLJ4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia sp. 8Y|TrEMBL
MSASSSDSPVWFITGCSTGFGRELAAAVIDRGWRAVVAARNPQSVTDLVERAAGRAIAVQ
LDVTRAEEIAAAVNAAHESFGHIDVLVNNAGFGYLAAVEEGEEDEVRAMFEANFFGAAAM
IRAVLPRMRERRAGHIVNITSVGGLVGNPGSGYYAATKFALEGLGEALGRETEGLGIKVT
AVEPGPFRTDWAGRSLRQAKQAIDDYAEVAGRRRAGIAQQSGKQPGDPARAAQVIIEAVQ
SSRPPAHLVLGNAGMELVRGKLGRLTRDLDAWQARSAWSDNPVE
>A0A098G903|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella fallonii LLAP-10|TrEMBL
MDLKTVTTKGIRSHKAHFSGWKNAVVLITGASRGIGRAMAKAAADRGAKVGLMARSQQDL
ELVLKEIDGQGVISVADVSHPDDVKQAIQCVAEQLGPIDILINCAGIGAFGSFNTAEIEL
FEKLMRINFLGVVYTMKAVLPSMVARHKGCIINIASVAGRIAAPLEAAYSASKFAVVGLT
ESVQNEVRSQGVHVSMVLPGPVETDFFATRGSPYPFESPKPVSPQKVVNAIIAAVEQGFT
EKFVPSWLSWAYTARALIPSLHRMGINHMYSDHLKCENIKNDE
>Q9VZ19|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MERWQNRVAVVTGASSGIGSAIAKDLVLAGMTVVGLARRVDRVKELQRELPAEKRGKLFA
LYCDVGNESSVNEAFDWIIQKLGAIDVLVNNAGTLQPGYLVDMNPAVMQQVLQTNIMGIV
LCTQRAVRSMRERKFDGHVVLINSILGHKTMTATEGVAPDVNVYPPSKHAVTALAEGYRQ
EFFGLGTRIKITSVSPGVVDTEIVPDSIREAIKDRMLHSEDIAQGVLYAIATPPHVQVHE
LIIKPLGETM
>A0A086JTS5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MESLARRLCVYTLTWLAILGDADDLFQASRYKRDGSFLVPPHIWHVETAACRWMIHQRPN
VFRRLEADLRTESAFVGANHSLSWGDVLDACWSSSSFVSRALCLGIASFRGAAFALSAFN
SWREREKAQERKLAVLVTGSSSGIGLQVTRLLLALDFYVIGTRLHSEDPRCVFEEICRGN
SRLLLLPMDVTNAEDVARAVEATKKFLRENDVSGLYALVNCAGIWNWNFIQTQSPQETEK
SLKTWRELFDVNLLGAVRVMHAFLPLMQARAVFVGSILGRMSSPGQTAYCASKAAVRLLA
EGARSDARDAGVNVVLVAFLAEVRVAPAQHVKSSTCVFAKETLTLCHPGRRRRTRGQLSP
RHPRGCFYRPVQSSAGARLSSRANRERNCRLHSLCSDAAHCSLCWMGYVRMETA
>G3T601|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Loxodonta africana|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSQSFKVYATMRDLKAQGPLWEAAQARRCPSGSL
EILQLDVRDSDSVAAARARVTEGRVDVLVCNAGRGLVGPLEAHVTGAMSSVLDVNVAGTV
RTLQAFLPDMKQRRSGRVLVTGSMGGLMGLPFNAVYCASKFALEGLCESLAVLLPSFGVH
VSLIECGPVHTAFQEKLEGGLGGALDSADTKTRDHFFCYQRHCERVFREAAQDPEEVTEV
FLKALRAPQPALRYFSTEHFLPLVRLRFDDPSGCSYVAAMRRAVFED
>G0AJA5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Collimonas fungivorans (strain Ter331)|TrEMBL
MQTMENELQNALRYDGRVAIVTGAGNGLGRVHALLLGARGAHVVVNDLGGDVHGGGKSSA
AADQVVAEIKAAGGSAVANYDSVEDGSRIVQTALDHFGGVDIVINNAGILRDSSFAKMSA
DDWDLIYRVHVLGAFRVTHAAWPHLRNKGYGRIVMTTSAAGIYGNFGQANYSMAKMGLIG
MANTLAIEGAAKNVLVNTIAPLAGSRISETVMPPQMMEALKPEFVAPLAAYLCHESCREN
GSLFEVGAGFHAKLRWQRTQGHHFHGQAFGPEQVARHWQEIVDFDDATYPASIGESLMSI
VQDVGSPFGQSKA
>A0A673WK62|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Salmo trutta|TrEMBL
MEQTVVLITGCSSGIGLSLAVRLASDPAKMYKVYATMRNLAKKERLLDCVKGLHKDTLDI
LQMDITDQQSILDARDRVREKRVNILVCNAGVGLMGPLEAQSLATMRQILEVNLLGTIST
IQAFLPGMKAQGHGRILVTGSIGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLDNLQRAEPGDTSLQQVDAHTLSLYDTYLQHCGMVFQNAAQDTEDIVKV
FLDAIQSSNPAFRYYTNNALIPLSSPKISALDGSQYIRNMSNIIFSTNGKGEQK
>U5RNX8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Clostridium autoethanogenum DSM 10061|TrEMBL
MTLNNEKTVLITGASSGIGLELAKLFSKDGYNLILVARSENKLEEIAKNLIKKYNINVHI
IKEDLSKRESVKDLFLKVQQLGIRVTTLVNNAGAGYCGLFHEIDIDKDEKMIGLNIEAIT
YLTKLFSKEMIKLKKGSILNVASTGSYEPGPYIAVYYASKAYVLSFSQALENELKPYGIK
VCTLCPGATKTGFSKNAGKKDIKTAMSAEKTAEIAYRGFMKNKSVIIPGFFNKIAVLFCK
LLPGKISAVVVRRIQENVTKNF
>F6GJ01|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Lacinutrix sp. (strain 5H-3-7-4)|TrEMBL
MKDLKNKIVLITGGASGIGKIMARLMLERQSKVILWDINQENINNTLKEFSNYKTIYAYK
VDVSNIENIKEQALKVKQDIGIVDVLINNAGIVVGKFFNTQTYADITKTMSINANGPMYV
TVEFLSDMIHKNTGHICNIASSGGLISNPKMSVYAASKWAVIGWSDSLRLEMLQLKKNIN
ITTIMPYYINTGMFNGVKSKIPILEPEATALTIIKSIEKNKRMVTIPGYIYRVTRLGQAL
MSVNMFDWFTGKVLGIYKTMEHFVGHKKA
>A0A8D0GKL1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sphenodon punctatus|TrEMBL
MEKVVVLITGCSSGIGLGLAVRLASDASHRFKVYATMRNLSKKERLLESVQDCHADTLEI
LQLDIVDPLSLAAATQRIREQRVDVLVCNAVVGLMGPLETYSYQAMKNIFDINLFGTIST
IQTFLPGMKQRKAGKIIVSSSVGGLQGVPFNSAYCASKFAVEGLCESLAIVLQEFNVHIS
LIECGPVNTSFLTNLQSTDPEGSTLQGLDPETHGLYRRYIQHCQGLFRDVAQDTEEVIQV
FLEAIQAPHPPLRYFTTQFFMPFTKLKLSCPDGSEYVRAMHKFVFSGAHA
>A0A087BH13|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bifidobacterium merycicum|TrEMBL
MAYALITGASSGIGRELASLFAANGYDIVITARNQERLNTVQTALKQQYQVRVVVFAADL
SEPDAPQRLHDFTTSHGISIEYLVNNAGFADWTGYLDADWSRQQEMMRLNMEALAELTYR
YGRDMRRAGHGRILNISSVASMMAGPYMAVYFASKAFVRSLSEAVAYELRNTGVTVTCVC
PGPTTTGFAKAANMHGRNFFTMTRPASARQLAAYAYRRMMRGTTLAYHGPLTRAGALAER
LLPRAAIRRLAAFMNGGEPNSRSVSATPQAHPERSAQD
>D5PIZ9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mycobacterium parascrofulaceum ATCC BAA-614|TrEMBL
MARWLITGCSTGFGREIAGAALAAGHDAVVTARRADAVRDFAEEFGDRALAVALDVTDAG
QIAAALSAAEAAFGGVDVLVNNAGHGYLSAVEEGEDAEVRKLFEVNYFGAVNMIKAVLPG
MRARGSGHIINMSSMTGLVANPPNAYYSSTKFALEAITEALATEVRPLGIKVTAIEPGAF
RTDWATRSMKESGTPIADYVDVAARKDLIKQFADHLPGDPKKVAEAVLMVTTLDEPPLRL
LLGRDVLKAMRDKIAALSASIEEWKSVTKDVNFEGS
>D5PG91|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mycobacterium parascrofulaceum ATCC BAA-614|TrEMBL
MQGFAGKVAVVTGAGSGIGRALAVELARSGAKVAISDVDLEGLAETEAQLKAIGAEVKAD
RLDVTEREAFLAYADAVREHFGKVNQIYNNAGIAFTGDVEVSQFKDIERVMDVDFWGVVN
GTKAFLPHLIASGDGHVINVSSVFGLFAVPGQAAYNSAKFAVRGFTEALRQEMAAAGHPV
AVSTVHPGGIKTAIARNATAAEGLDREQLASVFDKRLARTSPQRAAQIILDAVRKKKARV
LVGTDAKVLDALVRLTGAGYQQLFGPVMGRMMPKQ
>A0A086QGT6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii VAND|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALVRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKAMAIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>E3TDR7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ictalurus punctatus|TrEMBL
MANIRKLKGMVGLVTGGASGLGRATVERLVNHGASAVILDLPSSDGHNVAAALGERCAFA
PADVTSESDVRSAVDLAKEKFGRLDLAVNCAGIAVAVKTYNFKKDIPHSLEDFSRVINVN
IAGSFNVIRLAAGMMGKNEPDADGHRGCIVNTASVAAFDGQVGQAAYSASKGGIVGMTLP
IARDLAPMGIRVVTIAPGLFSTPLLAGLPEKVQSFLARQVPFPSRLGDPAEFAHLVTAIA
ENPMINGEVIRLDGAIRMQP
>Q1PLL0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Danio rerio|TrEMBL
MYTSGIVLYVSFIRSNKRPIAFTSKWRSRGAVAVELSIERRPLVILSSLTTLYFRKIFTL
AGVFSCDSGFGHELAQVLDRAGMRVFAGVLDELSPGALKLKESASVNLTVLQLDITNNTQ
ITQTHQFIKSQTGKTGLWALVNNAGVLGYVCDGEILPMKMYKSCLDVNFLGSVMMTHTFL
PLIRQSRGRVINITSMAGEVPLVGFAGYGASKAALNIYSGAIRQELSRWGVRVIIVQPGA
FRTNILGSSEQWERAQEQILSGLSEEVKDSYGEEYIHSMQKRLLDMSSASSEDKGPFLQS
LKHAILSSNPKHFYYPGAGAWVLSLLYRYCPTALSDKIFSGMFMSGVQPAELARAIPH
>V4ZM35|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
MDLFSCGCIKALNSHVQALIGACPFVQLAATTLGLALLCCVSLALVRRGFKILFTRKFQL
DKFGEWAVVTGATDGIGKALVIQMAKKGMKIFLISRNEERLRQTEQDLQAAVPALRGVKS
FAVDFSEGSTESLFQKLDAALKNLDVGILVNNVGVSYPHAMFYDELDLETLDQLINVNVR
STLVTTRVLYPGMVSRRRGAIICVGSGASEIASDPLYCAYSATKGAAEAFCRSLQPECAS
KNILVQCHVPLLVTTKLSKMRKTNLMTPSTEKYAKAAVAAIENGSLRGPTTISPYCVHRC
IIWLSNAVPRRIWEAAYLPRCLSIRKRALKKKEQQAEAKKDM
>B7P9E2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MSSASNFFEERLALVVGGGGGIGRCVCLAFAKEGCRVVVAGRNLEKATAVAKSLPGKGHE
ALQVDVGQSKSVASLFEDISRLCSQPASIVVNCVGIGNPPTPLVDLPEAMFDNVIRVNLK
GTFLITQAAARAMIAGNVRDGAIVNVSSFVSKLCLPRRGEYAASKAGVVALTKVAAKELA
SKGIRVNSVLPVLTTTPMAGGNRKPEKENKAVQDIPLKRASRPEEVADVIVFLCGSGSSF
MTGAAVDIAGGL
>B7PSR3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MSLRRIAAMRTILGTSVRVLLRITRNYTPMYSVSSTGESSGVGSDHVHRHEGSSSLQLGR
RLALVTGGASGIGQSVAKVLAREGATVIVADINMTGTKETIKMLQDIMDSGHKGMYADVR
RSADVETLFKDIRSAFPERNLSLVVNSAGILQTPTPVDRTSDDVFDNIVATNLRGTFLVT
RESVKFMLANNVTDGAIVNIASIGGKGGLPGVAAYAASKGAVLAFTKSVARELGTKGIRL
NAILPALTDTPMISQYPPELIRNRIMIDIPMQRKAEPIEISETIVFMLSPKSSFMTGASI
DVAGGMYS
>E0V951|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pediculus humanus subsp. corporis|TrEMBL
MMNFFNVSAYVGAFFVAWFILDLLIKIIQGIRAHFMSEMIPLSVKFGTWAVVTGSTDGIG
KAYALGLAKRGINIVLISRNEKKLTDLSQEIMHRHLVTVKTITADFSKGEIIFDKIKKEL
EDIPVGMLINNVGKQYTRPMYVGDVNDRELWDIININIATTVMMTKMILPKMVERKKGGI
VNISSGSEHQPLPFMTVYAASKAFIKSFSDALRFEYRKYGITVQHLSPMFVNTKMNDFSH
RLRQTGIFIPDAETYANNAINLLGILNNSSGYWAHGLQSYLTKIPPIWIRTYIGAIMNQV
FMNDYYNNNNSNNNTNGNNKITSDSMDRVKEIKKN
>A0A8C4SJ23|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Erpetoichthys calabaricus|TrEMBL
MEKAVVLITGCSSGIGLGLAVRLAYDSSGAFKVYATMRDLSKKERLLECVRGGHEDTLKI
LQMDITDQKSILAVKQNIEEKRVDILVCNAGVGLLGPLELLTQDTMQQILDVNLFGTIRT
IQTFLPEMKARRSGRIIVTGSLGGLQGFPFNDVYCASKFAVEGLCESLAIQLHHFNIHIS
LIECGPVNTNFMANQHKTSPKESELQKIDAKTKALYQAYIQHCQRIFQDDMQDTENVVQV
FLEAIAAETPALRYYTNTSMPFNRLKLSFQDGSQYIKAASKFLFPDEQLTDL
>A0A835WY44|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Nitrosopumilales archaeon|TrEMBL
MVNNAGLMPLSFIKNLKVDEWDQMIDVNIKGVLYCIAAVIPHMLEKKSGHIINISSVAGR
IVFPSGTVYCATKHAVTALSEGLRQEFSTRKNIRVTCIEPGVVGTELTKTITDESLQSFV
ENAKKMESLNAEDIANAILFALEAPNHVNVNEILIRPTTQER
>A0A8C4W5P6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Gopherus evgoodei|TrEMBL
VNPTPAMEKTVVLITGCSSGIGLGLAVRLASDASRRFKVYATMRNLAKKERLLECVRGCH
ASTLEILQLDVTDPLSLAAAVQQVQEQRVDVLVCNAGVGLMGPLETCSYQAMKNIFDVNV
FGTISTIQAFLPGMKRRKAGKIIISSSVGALQGIPFNAVYCASKFAVEGLCESLAVILQQ
FNMHITLIECGPVNTSFLANLQHSDTEGSALQGLDPQTRTLYSQYLQHCQSLFRDVAQDT
EEVLQVFLEAICAPCPPLRSFTTQVFMPLTRLKLTSPDGSEYIRAMHKFVFSAGEAQGDR
T
>E8U6Y5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Deinococcus maricopensis (strain DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34)|TrEMBL
MRPLPLLLAGLGLLAWSRRPRPLAALSDRVVLITGGSRGLGLALAQECARLGARLVLTAR
DEQELDRARVTLTGTEVLTVPADLTRPGEGERVVQAALARFGRLDVLINNAGIIQVGPLH
HLNASDYQQAMAINFFAGVHLTYAARPHLRRTRGRILNITSIGARVPVPHLASYVASKFA
MRGFSRVSRAELARDGITVVTADPGLMRTGSARHAETRGQTKREYLWFALGDNAPILSLN
ADEAARRLVQALRRGEPEVVVGGPALALAYAERLAPNVLSGLLNVMNRSLPTPTRQPERE
VGAQSETPLTRANPIKQAAEQRWNADAR
>A0A2K5CWZ5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Aotus nancymaae|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATMRDLKTQGQLWEAARAQGCPLDSL
ETLQLDVRDSKSVADAQACVTEGRVDILVCNAGQGLLGPLEALGEDAVGSVLDVNVAGTV
RMLQAFLPEMKRRGSGRVLVTGSMGGLMGLPFNDVYCASKFALEGLCESLAVLLPPFGVH
SVSLIECGPVHTPFMQKVLGGPGGMLDRTDTRTRLLFHQYLQHNKEIFREAAQHPEEVVE
VFLTALRAPKPALRYFTTERFLPLQQMRLDDPSGSSYVAAMHRNVFPREPAEAEAGAGAG
ASGVGDPELGDPLAAPQ
>A0A7N4NU37|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sarcophilus harrisii|TrEMBL
MERKIVLITGCSSGIGLHLALRLAADPSGSFKGEKRAEAKDQLWRSQGPLWEGARARGCP
PGSLETLQLDVTDSSSVAAARDHVTEGRVDILVCNAGRGLLGPLEAHAVEAVGSVLDVNV
VGTVRTLQAFLPDMKRRRAGRVLVTGSVGGLMGLPFNAVYCASKFALEGLCESLAVLLLP
FGIHISLIECGPVRTAFQEKLEGGPGGVLGSADLETRALFSRYQQHCERLFREAAQDPED
VVEVFVRALGAPCPVLRYFSTERFLPLAGLRLSDPGGSQYVDAMYRAVFSEPEEEDNRED
DGTEGL
>Q8IPP8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|TrEMBL
MNFAGKVVLITGASSGIGAATAIKFAKYGACLALNGRNVENLKKVAAECSKVSQSQPALV
VGDIAKEADTQRIWSETLQQYGKLDVLVNNAGIIETGTIETTSLEQYDRVMNTNLRAIYH
LTMLATPELVKTKGNIVNVSSVNGIRSFPGVLAYNISKMGVDQFTRCVALELAAKGVRVN
CVNPGVTVTNLHARGGMDAETYKKFLEHSKTTHALGRPGDVKEVAAAIAFLASDEASFST
GVSLPVDGGRHAMCPR
>A0A8C7B3Z2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Neovison vison|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSRSFKVYATLRDLRAQGPLWEAARSRGCPPGSL
ETLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLEAHTAGAVGSVLDVNVAGTV
RTLQAFLPDMKRRRSGRVLVTGSMGGLMGLPFNAVYCASKFAIEGLCESLAVLLPPFGVH
VSLIECGPVRTAFLEKLEGVTGGVLDGADAETRHLFSRYQRHLEQIFREAAQDPEEVTEV
FLEALRAPRPALRYFSTESFLPLAHLRLADPSGCSYVAAMHRAVFADEPAEEPTSAAPGG
PVLRAPPAAAAPQ
>A0A1N7RT50|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Paraburkholderia ribeironis|TrEMBL
MNEATTRTVLITGAASGIGRAAAHRFASAGWRCMLVDLNGAALEGCVARLPVTGEAAHVV
CVADLTRPDQIAELAVGAPALDAIVNNAGMSDSSNVPLVEQDAAQFARLVALNLDAPAQV
FSTFAPSLRAAARIVNVASGAGRRGVSRHARRIGARRRAGAAPRRRARGGRARGQKT
>G1LIW7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ailuropoda melanoleuca|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSQSFKVYATLRDLGAQGPLWEAARSRGCPPGSL
ETLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLEVHAAGAVGSVLDVNVAGTV
RTLQAFLPDMKRRRSGRVLVTGSMGGLMGLPFNAVYCASKFAIEGLCESLAVLLPPFGVH
VSLIECGPVRTAFLEKLESVPGGALDGADAETRDLFSRYQRHLERIFREAAQDPEEVTEV
FLDALRSAPALRYFSTESFLPLAHLRLADPSGCSYVAAMHRAVFADEPAEEESAAAPGGP
ELRAPPAAAPQ
>A0A8C4HPM2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Dicentrarchus labrax|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPNKKFKVYATMRNLAKKERLLECVKGLHKDTLDI
LQMDVTSRQSILDARDRVVENRVDILVCNAGVGLMGPLEVQSLDSMRQILEVNLLGTIQT
IQAFLPDMKAQGKGRVLVTGSTGGLHGLPFNEVYCASKFAIEGACESLAVLLQHFNIHVS
LIECGPVNTDFLVNLQKTELGDESLQLVDTHTLSLYEKYLQHCGSVFQNAAQDTEDIVKV
FLDAIQSPSPAFRYFTSGVMPPLTKLKITEPDGSRYISAMSKIIFSAEEQ
>A0A673ZQJ0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Salmo trutta|TrEMBL
MEQTVVLITGCSSGIGLSLAVRLASDPAKMYKVYATMRNLAKKERLLDCVKGLHKDTLDI
LQMDITDQRSILDARDRVREKRVNILVCNAGVGLMGPLEAQSLATMRQILEVNLLGTIST
IQAFLPGMKAQGHGRILVTGSIGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIYVS
LIECGPVNTDFLDNLQRAEPGDSSLQQVDAHTRSLYDTYLQHCGMVFQNAAQDTEDIVKV
FLDAIQSSNPAFRYYTNNALIPLSSPKISALDGSQYIRNMSKIIFSTNGKGEQK
>A0A0B9A3C8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Brevibacterium linens|TrEMBL
MTRGTKIAGSRILITGAGSGIGRLMALEAADRGAAEVIIWDLSAETGEAVRQEIEAKGVR
ARTFSVNVGESAQVASTAQDVGDIDILVNCAGVVTGKKLLDADEAAIRRTFDVNTMALYW
TTKAFLPGIRERNHGSIVNIASAAGLTGVAKQTDYSASKWAAVGFTESLRGELRAEGSRV
NTLVVCPFYINTGMFAGVQTKFPRLLPILEENNVSTQVIDSIESGREQLVMPSLVRLVPG
VRLLPTRAFDAVMDFLGVNQTMDHFTGRTGGDSPRSRRAARRRQPAGV
>A0A1Y5PAT7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|uncultured Mycobacterium sp|TrEMBL
MSEKVWFITGTSRGFGREWAIGALEHGDKVAATARDTGTLADLVQTYGDAILPIQLDVTD
RDADFAAVKLAHDHFGRLDIVVNNAGYGHFGFIEELSEKDARDQLETNVFGALWITQAAL
PLLRAQGSGHIIQVSSIGGITAFPLVGIYHASKWALEGFSQALAQEVAPFGIHVTLIEPG
GFDTDWSGPSSKRSVELPDYAELHRQVDEMRATRWAKPGNPKASATAIRKIVDAPTPPLR
AFFGESPLQTAKADYESRLANWEQWQPVAIEAQG
>A0A4X2M530|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Vombatus ursinus|TrEMBL
MERKVVLITGCSSGIGLHLALRLAADPSGSFKGGKRAGAKDPGGVEGCLVSGDEGREDLC
PRGSPNSRQSSLNSVYATLRDLGSQGPLWEGARARGCPPGSLETLQLDVTDSCSVAAARD
HVTEGRVDILVCNAGRGLVGPLEAHTVEAVGSVLDVNVAGTVRTLQAFLPDMKRRRAGRV
LVTGSIGGMMGLPFNAVYCASKFALEGLCESLAVLLPPFGVHVSLIECGPVRTAFQEKLE
GGPGGALGSTDLETRALFSRYQSHCERIFREEAQDPEDVVEVFVRALSAPRPVLRYFSTE
RFLPLAELRLSDPGGSQYVNAMHRAVFSEPEEGEAGSEAKGLEKGGGEEGRTEFGLNQIK
M
>G7LKB3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Brenneria sp. EniD312|TrEMBL
MYYTPQNDLLQQKIILVTGAGDGIGREAALTYARFGARLILLGRTESKLQAVKQRIQEEN
GAQAHIIVCDMLTTNSARFFQLADELAQVTPRLDGVLHNAGLLGEIAPMARQSADIWHDV
MQVNVNATFMLTQALLPLLLKSPGASLVFTSSSVGRQGRADWGAYAVSKFATEGMMQVLA
DEYRQQNLRVNCINPGGTRTGMRAAAFPDEDPEKLKTPADIMPLYLYLMGDDSRRKTGMS
FDAQPGRKSGPAE
>A0A098GF25|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Tatlockia micdadei|TrEMBL
MQSSQRVAVITGAASGIGLALSEICLQQGMHVVMADNAVTALCNQVEQLSDKVETEVLGV
VCDVAKPDSFKHLAKQTYEHFNRVDWLFNNAGISGQLAPIWELTNEHIRKVMDINLHGAI
HGIQAFLPLMFQQTHRSHIINMASFYGLCSGSQMAAYAMSKHALVALSESLHFDLKRLDK
HVDVSVVCPSFASTSLLANSAPLHTDKLHHMVADLIARSRPASDVAEHIVREVKNKTFYI
LPDREVKEYCTQRTTAIIEQTEPHQHSLEKIIASLSKRALKESLVNE
>A0A8C2M523|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cricetulus barabensis griseus|TrEMBL
MDRTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKAQGPLLEAARARGCPPGSL
QTLELDVRDSESVAAAQACVTEGRVDVLVCNAGRGLFGPLEAHELDAVGAVLDVNVVGTV
RMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAILLPRFGVH
VSLIECGAVHTAFYEKLEGGPGGALERADAQTRYLFAHYLRGYEQALSEAQDPEEVTELF
LTALRAPQPALRYFSTDRFLPLARMRTEDPSGSSYVAAMHQEAFADLQAQEGAEAGAGVL
GDPARASSSFICLPGCATPGVTSELCCPDKPCFQQKN
>A0A8C2M523|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cricetulus griseus|TrEMBL
MDRTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKAQGPLLEAARARGCPPGSL
QTLELDVRDSESVAAAQACVTEGRVDVLVCNAGRGLFGPLEAHELDAVGAVLDVNVVGTV
RMLQAFLPDMKRRHSGRVLVTASVGGLMGLPFHEVYCASKFALEGLCESLAILLPRFGVH
VSLIECGAVHTAFYEKLEGGPGGALERADAQTRYLFAHYLRGYEQALSEAQDPEEVTELF
LTALRAPQPALRYFSTDRFLPLARMRTEDPSGSSYVAAMHQEAFADLQAQEGAEAGAGVL
GDPARASSSFICLPGCATPGVTSELCCPDKPCFQQKN
>A0A2G8XSM2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Toxoplasma gondii COUG|TrEMBL
MNIARRWASRVAMVLSLFALSLSWSFLLRATSPLLPSLALRSPESRQRSQERASRFPERK
KDRCCLVLLLLLITAGKSAEAGLWALSLFSLFLSPRSLSLDHSQSWGDVLDACWSSSSFV
SRALCLGIASFRGAAFALSAFNSWREREKAQERKLAVLVTGSSSGIGLQVTRLLLALDFY
VIGTRLHSEDPRRVFEEISRGSTRTPEGGAEPRPAAAGERPRREETEEREDERERERKED
SRVESGESGETIGQTKQDGAEHRRRWRGSRTQRRRPAEAREGADRERGDAGVTENREQEN
VQTECGVGDETSSRLLLLPMDVTNAEDVARAVEATKKFLRENDVSGLYALVNCAGIWNWN
FIQTQSPQETEKSLKTWRELFDVNLLGAVRVMHAFLPLMQAFNASASTGGGASVSAWRLA
SLCAEAVHAVRHHRVLPALSSRAVFVGSILGRMSSPGQTAYCASKAAVRLLAEGARSDAR
DAGVNVVLV
>B9RMR2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ricinus communis|TrEMBL
MELCFVDKLKSQPLWFLVLFSLGSLSLLRCFFTILNWVYVNFLRPAKNLKKYGSWALVTG
PTDGIGKGFAFQLARKGLNLVLVARNPDKLKDVSDSILSKYGKVQIKTVVVDFSGDIDEG
VKRIKDTVEGLDVGVLINNVGVSYPYARFFHEVDEELLKNLIKVNVEGTTKVTHAVLPGM
LKRKKGAIINIGSGAAIVIPSDPLYAVYAATKAYIDQFSRCLYVEYKKSGIDVQCQVPLY
VATKMASIRRSSFFVPSTDDYARAGLRWVGYEPRCTPYWPHSLIWGLISIVPEFAVDAWR
YKFNLGIRKRGQQKDARKKE
>G4FQN9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Synechococcus sp. WH 8016|TrEMBL
MNLRGSVYLVAGASGGIGKSLSTLLHSLNATVVLVDLSTESLVDLVDDLSKSNPNAPKPQ
VFAADISSESSLKDLTTWYSAHFQHINGLINCVGLLRTGESLKPISETSLSEWETIINVN
LTGTFLLNRAFIPIMQKQRFGDIINISSVSGTQGRAFDGPYCSSKFGIIGLSESIAAEVS
SSGIRVQCLLP
>U3JD55|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ficedula albicollis|TrEMBL
DQGTESPRHRTTVLITGCSSGIGLGLAARLAADATRRFKVYATMRDLAKGERLLQCLGGH
CPDTLEVLQLDVTDPCSLAAAAQQVQGQRLDVLVCNAGVGLMGPLETCSDQAMKTLFDVN
LFGAVRTIQTFLPAMKSRRAGRIIVSSSIGGLQGLPFNAVYCASKFAVEGLCESLAIVLR
PFNIHLTLVECGPVHTSFQANLQRPDPEGSEMRRLDAETQGLYRRYLGHCQSIFRDAAQE
VEEVLPVFLDAIGSPCPPLRCASTQLLAPLWRLRLSSPDGSAYVRAMHDFVFGGSEAGRE
QP
>A0A378PA28|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella quateirensis|TrEMBL
MTNINNNKAALVTGASHGIGLELAKILLGDGWVVYGTGRDVSSLADTKALFPRFVPIQSD
FTRNSDIEEVAKIINEFGIPLHLLVQNAGMKSPPRPLTEYDCDSIDEVFQVNLLAPMKLT
ALLALGMPEKSRILFVTSRAATLKLKESSTYCASKAGLDEVTAIVRKELAEKNIGVSCVI
PGEVDTRIQKILRETTSFHLHKMFDEAYQSGQLISPETCAEFLKWFLCNLSFDEFKQSNM
PVSIYEEWHHPFWLRDRNQLPPFPF
>A0A2R9CKT5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pan paniscus|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKGREGRSPWRPEGKSDLPPLPKPPVYATL
RDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLL
GPLEALGEDAVASVLDVNVVGTVRVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYC
ASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFY
QYLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYV
TAMHREVFGDVPAKAEAGAEAGGGAGPGAEDEAGPSAVGDPELGDPPAAPQ
>A0A411ZAG1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Altererythrobacter insulae|TrEMBL
MSDRKSIFITGGGSGIGREVAIYFAKRGWFVGIADISDQGMQDTLGLIEGGFKYSHKLDV
RDRNAWDEALNAFSTAAGGRIDVVFNNAGIGHGGPIIEQPSDEVVSLLDVNLKGVIYGAQ
AAYPHLKKTAPGSVLLNTASLAGIIGGPNLSVYCATKWGVRGLTNSLDAEWAKDGIKVAS
LCPGFIDTPIIEQTAEGTNQSVKEQLEDAGVEVNPVSIVPEVVWNAVHGDKLDYTVGKMA
KRLLFLSRWMPGRVRKEMRTNGIGTEDINTAR
>A0A7U7HC91|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Chryseobacterium sp. JV274|TrEMBL
MSKTILITGAASGFGKIAAFDLAKKGHKVIATAQVYPQMSDLIREAKEQGVEITVDKLDV
TNPRDIAYIHGKYDIDILISNAGIMEGGPIAEQPIDLIRSMFDVNVFGGLELAQGFIKKW
IDQKKPGKIVFTTSMGELWTVPYVAAYCASKHAMGSIAEGLRTELAQFNIKIATCNPGVF
GTGFNDRGVDTISRWYNPETNFTPPSVFDGTAESLAHQLDPQSMAEVIVNVALDDESHFR
NVHPKDTEDFVKQLQADAWTAKS
>A0A378IIT1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella cincinnatiensis|TrEMBL
MKVAVITGAANGIGLALTQVHLQQGHFVVMVDKDSGKLKNEATRLLALFPEKILEVCCDV
TKPNHVSQLAQQVQFELGRVDWIYNNAGIIGQLSPIWDLCPEHIQKVMDVNLFGMIHMIQ
AFMPFLFQQTFYSHIVNIASLYALCTGSQTPSYSMSKHAVLALSESLYFDLERMEKPVNI
SVVFPSFTDTALLSSNEHTPSQFQEMLKSLLSHSRPALDIAEYIIHEVEQKKFYIFPDKE
VKGYCEERTKAMILQETPHVTNIEKLMSALIKRQSKNSS
>B2J7D9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MPKTVFITGTSSGIGKFTTIYFAQQGWNVAATMRNPSQDQNFREFPNIKVYFLDVTDNNS
IQTAIASAIQDFGQIDVLVNNAGYGVDGVFEAMTDEIIAKQFNTNVFGLMRITQAIIPHL
RQQGGGTIIQIASMGGRITFPLYSIYHSSKWAVEGFSEALHYELEPFNIKIKIVEPGVIK
TEFYENNRAIVRDDLPMYQPLVDTTQRVSQEAGRKGEPPELVAQAIFKAAIDRSYKMRYC
VGQPAPILLMLRKLLPDNWFFSIIKRIYNLPSGSKTVTPQK
>K9XFK8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Gloeocapsa sp. PCC 7428|TrEMBL
MQNKVVVVVGATGGIGSALSHKLARQGAQLVLAARDSHKLSQLVNQLDAGAGQTLAVPTD
ITDWQQVDILMEKTIAQFGQIDALVNAAGAGVMKPYGNLEPADLEAMLDVNLKGSFYTSQ
AAAELMQERKSGHICNVVGILGKHSMPMAAAYCASKYAVVGFSKCMAEELKRFGVKFTLF
YFGGVNSPFWDNVQLKLDRKKMLSTETAAEAILYALSADPQAVPMEINIQPDSHLFF
>A0A653TLZ1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Citricoccus sp. K5|TrEMBL
MAEQIDERALQQDELVPPGTSSRGTGQTILITGATAGLGAEFARQLAGQGHHLVITSRNP
LQLVAKAQGLEAQYGISVETLTTDLSTAEGVDVVAARLRQREQPITMLVNNAGSGLATEF
HESESEDELAMLKLLVEAPMLLSHAAIQAFLARGGGRIINVSSVAGFIPEGSYGAAKAWS
ISFSRWANTRYKPDGVTITALCPGPVRTEFHTRAGIDTSKKPKWAWMDAEDVVREGLTAA
AEGRSVCIPSRRYRSLMAAARFSPDAVVERFSRIEPKAR
>A0A3P8TI84|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Amphiprion percula|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPDKRFKVYATMRNLAKKERLLECVKGLHKDTLDI
LQMDVTDRQSILYARDRVVEKRVDILVCNAGVGLMGPLEVQSLDSMRRILEVNLLGTIQT
IQAFLSDMKARGQGRILVTGSTGGLHGLPFNEMYCASKFAIEGACESLAVLLQHFNIHVS
LIECGPVNTDFLVNLQKVELEDATLQQVDAQTISLYEKYLQHCSSVFQNAAQDTEDIVKV
FLDAIQSPSPAFRYFTTSVVPPLTKLKMTEPDGSQYISAMSKIIFSAEDQ
>A0A8C6NJG1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Nothobranchius furzeri|TrEMBL
MEKKVVLITGCSSGIGLSLAVRLASEPSKTFKVYATMRNLAKKERLLECVKDLHQGTLEI
LQMDVTDRQSIMQAKDMIVEKRVDILVCNAGVGLVGPLEVQHLDSMRHILEVNLLGTIQT
IQAFLSEMKARRQGHILVTGSTGGLHGLPFNDMYCASKFAIEGACESLAVLLQHFNIHVS
LIECGPVNTDFLVNLQKAELGDPSLQQVDTQTLSLYEKYLQHCSSVFQNAAQDTEDIVKV
FLTAIQSSSPALRYFTGSVVPPLTDPKLTQPDGLQYIRAMSKIIFSSEEQ
>G2MNA2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|halophilic archaeon DL31|TrEMBL
MRPETVLITGCSSGIGHATAEAFLADGWQVYATARDPEDIADLEEHGRCTTDTLDVTEKS
DIRNVVNRIIRTEDRIDCLVNNAGYGQFGPIEELPVDKVETQFDVNVYGPHRLTRAVLPH
MREAGEGTVINLSSVAGRISFAGGGAYCGSKFALEAMTDALRQEVEGHGIDAVLIEPGPV
RTGFSDRASDESEEEQADRTGAYEWFWKAFEDSEAIGGDGPGSVEPEHVATDILDAANLT
DPPARIPVGTVAELIVKARYLPASLQDAAIRLVRKRLL
>W6W569|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhizobium sp. (strain CF080)|TrEMBL
MTKTILITGTSSGLGRATAKLFHQNGWNVIATMRTPERETELTQLDNVLVTRLDVQDASS
IRSAIDAGLARFGRIDALVNNAGYGAYGPLEATPFEKIRRQFDVNVLGLLATTQAVLPHF
RANRSGTIVNISSIGGRMAFPLGTLYHGTKFAVEGLSESMQYELAPLGIAVKVIEPGGIR
TDFSGRSFDMSNDEGLAEYQPLVQSLFGFFGPMMENASEPELVAEVIYGAATDGADQLRY
AAGADAVQILASRAASDDATFFGGMKAQFGL
>B7PCL8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MAKGGGPHNAESCPFSSGGTPTSVMICSIIGLVFVVYVLVKLLISLWRGFYTCFLARWLG
FTVDFRKMGEWAVITGASDGIGRAYAEELAARGLNVVLISRTLEKLQEVASEIEKAYKVK
TKVISADFTGGNEIYEVIRRELEGLEVGVLVNNVGTSYSYPEFFSAVPEGDKVMDGIIRA
NCLAGTMMTRICLPQMDERRRGAIINVSSISAMHPLPLLSTYAASKAYMDYLSQGLQAEY
RERGVYIQSVMPAYVSTKMSKIRKASYMVPTAKTYVREALNTVGVEHATYGYLPHKFRAY
VQETLKNWLPHDMFMNISRSSLLSIRQLYYKKKGVEDVFLGKGKKTH
>A0A8C7MYG5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Oncorhynchus kisutch|TrEMBL
MEQTVVLITGCSSGIGLSLAVRLASDPAKIYKVYATMRNLAKKERLLDCVKDLHKDTLDI
LQMDITDQRSILDARDRVREKRVNILVCNAGVGLMGPLEAQSLATMRQILEVNLLGTIST
IQAFLPGMKAQGHGRILVTGSIGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLDNLQRAEPGDSSLQQVDAHTRSLYDTYLQHCGMVFQNAAQDTEDIVKV
FLDAIQSTNPAFRYYTNNALIPLSSPKISALDGSQYIRNMSKIIFSTNGKGEQK
>W4A6S2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhodococcus rhodochrous ATCC 21198|TrEMBL
MSEFAGKVAVITGAGSGIGRALALELARRGARLALSDVDTAGLDETVRRARDLGAEVKAD
HLDVTQREAVLDYADAVAVHFGQVNQIYNNAGIAYHGEFERSEFKDIERIMDVDFWGVVN
GTKAFLPHVVASGDGHIVNVSSLFGLLAIPGQSAYNSAKFAVRGFTEALRQEMLVARHPV
KVTCVHPGGIKTAIARNAAVPAGDDQESFAQFFDRKLARTSPEDAARTIVEGVRRGRARV
LIGADAKFLDAWVRVVGPSYQRVVAFVSGRFVPKG
>A0A096P5T5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Papio anubis|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARARGCPLGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEAVGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSMGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPDEVLNRTDIHTFHRFYQYLAHSKQVFREEAQNPEEVTEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVAAMHRHVFGDDPAEAEAGAGTGG
GAGPSGVGDPELGDPPAAPQ
>A0A087Y6A1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Poecilia formosa|TrEMBL
MSMEKKVVLITGCSSGIGLSLAVRLASDSSKVFKVYATMRNLAKKERLLECVKDLHRDTL
EILQMDVTDRQSILTARDKVVEKRVDILVCNAGVGLMGPLEVQSLDTMRRILEVNLLGTI
QTIQVFLSGMKAQGQGRILVTGSTGGLHGLPFNEMYCASKFAIEGACESLAVLLQHFNIQ
VSLIECGPVNSDFLINLQKAELGDPSLQQVDGRTISLYEKYLQHCSMVFQNAAQDTEDIV
EVFLDAIHSTSPAFRYFTNSVMPPLTQLKVTEPDGMEYIKTMSKIIFADEDQ
>A0A6J8DZ65|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mytilus coruscus|TrEMBL
MNTNIDYDEYLDDDIIFYSVLYSSVTVLFAMAVLSKFLTNEFRFGFRSVLSLAVLFLGEP
LCQFFIKGPSGVFAFAMCCLVIYSILPASHLPVGNKAVLVTGCDSGFGNSLVKKLDSIGM
RVFATCLSLNSPGAVSLQLACSGRLLYQTLNSLWGLVNNAGVWYYSELETTSETIFRKVL
EINLFGAIRLTKALLPLIRKSKGRIVNVSSLMGRLTMEGNGAYSMSKHALLAFSDTLRQE
MKKWGVHVSIIEPTGFYTENMKEHVINSRKAELWDTMDEETKVTYGQKYFDSIYESIIEG
SNRYPDDLTCVIRAMRSGLLSKRPRNRYPCGTGADFIMMLYPLLPVWLADKLISLISIMP
KDVRPAGLD
>A0A136MAP2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Candidatus Brocadia sinica|TrEMBL
MTTEIVVHIGKELLQITVVLMGPLLVVAMVVGLIVGIFQTISSIHEQTITFLPKIFAVMG
VFLLCLPWMLRMITSYTVNLLGNLTRYCQ
>G3P112|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Gasterosteus aculeatus|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPDKAFKVYATMRNLAKQERLLECVKSLHKDTLDI
LQMDVTGRQSILDARDRVVEKRVDILVCNAGVGLMGPLEAQSLDSMRQIVEVNLFGTIQA
IQAFLPGMKAQGRGRILVTGSTGGLQGLPFNEVYCASKFAIEGACESLAVLLQHFNIHVS
LIECGPVNTDFLVNLQRAELGDSSLQQVDGLTLSLYEKYLQHCGSVFQNAAQDTDDIVKV
FLEAIRSASPAFRYFTGGGVPPLIKLKVTHPDGSRYISALSKIMFSVNKGQLKQQ
>A0A0A0MQS7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV
RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
SLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAE
VFLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAG
GGAGPGAEDEAGRGAVGDPELGDPPAAPQ
>I2GCK4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Fibrisoma limi BUZ 3|TrEMBL
MKTVLITGTSSGIGKATARYFAENGWNVAATMRTPAKETELTKLPNVKLFRLDVMDADSI
RQAIADARAAFGGIDAIVNNAGYGAVGAFEAATPEQVQRQFDTNVFGVMNVIREILPYFR
EKRDGTIINVTSMGGLITFPSYSIYHGTKWAVEGFAEALSFELRPFNIRVKNVEPGAIKT
DFYDRSQDVLKKDGLTAYDEYVRVTLANTQKEGENAPGPEVVAKTIFKAANDRSFRLRYV
TGNSQTGALLTVRRLIPLSWFHNIVRGVVEKGYKAPAMSVGQGA
>A0A671EHT8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhinolophus ferrumequinum|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSRSFKVYATLRDLSTQGPLWEAARSRGCPPGSL
ETLQLDVQDADSVAAARARVTEGRVDVLVCNAGRGLLGPLEALSADAMHSVLDVNVVGTV
RMLQAFLPDMKRRGSGHILVTGSMGGLMGMPFNAVYCASKFAIEGLCESLAVLLPPFGVH
VSLIECGPVHTAFQEKVQNGPGAALDGVDAQTRDLFSRYQRHFEQVFRKAAQDPEEVTEV
FLTALRASPPALRYFSCERFLPLARLRLADPSGCSYVAAMHRAVFGDEAAEGPEGAQTEA
GAGALGGPELGAPPSAPQ
>A0A3Q2DJ58|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cyprinodon variegatus|TrEMBL
MKVVLITGCSSGIGLSLAVRLASDSSKIFKVYATMRNLAKKERLLESVKGLHRDTLEILQ
MDVTDRQSIMNAREKVVEKRVDILVCNAGVGLMGPLEIQSLDSMKHILEVNLLGTIQTIQ
VFLSDMKAQGQGRILVTGSTGGLHGLPFNEVYCASKFAIEGACESLAVLLQHFNIQVSLI
ECGPVNSDFLVNLQKAELGDESLQQVDGQTLSLYEKYLQHCSMVFQNAAQDTEDIVKVFL
EAIHSTKPAFRYFTNSVMPPLTNLKVSEPDGMNYITALSQIIFSDDQ
>A0A8D2HBM1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Urocitellus parryii|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSRSFKVYATMRDLRAQGQLWKAARARGCPSDSL
ETLELDVRDSDSVAAARARVTEGRVDVLVCNAGRGLLGPLEAHGLDAVGSVLDVNVVGTV
RTLQAFLPDMKRRGSGRIMVTGSVGGLMGLPFNAVYCASKFALEGLCESLAVLLLPFGVH
VSLIECGPVHTAFYEKLEGGPGGTLNHTDAQTRHLFSLYQRHCEQIIREAQDPEEVTEVF
LTALRSPKPSLRYYSTERFLPLSRLRLEDPSGCSYVTAMHHAVFADQPAEAAGTREPGDP
ELGASPAAPK
>B0ENI6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Entamoeba dispar (strain ATCC PRA-260 / SAW760)|TrEMBL
MVKNIGALLLGVLGGIVAIITVIPGLIFLWKTYCIVTGAAGGIGKAFAEKFAKEGFNLII
MDRLAEPLVELKKTLEEKYNVNVVDYVADFIAMDKNNEWNKVEELIANYDIGVLVNNVGM
CNYLPGKFGQLELKDINNMISLNIRTLLMMTHICIPKMEGRKEKGLIVNMSSSTSGYPHP
LIQVYSSTKAFVRQFTDSIYAEYKGKIDVIAYTPWYIKTDMTKIRENAIYALTPSDFVDY
AFRYFGQQNHINPYWFHYLMDIGTSTIPEAIFSKSVIKQQTFVRKRLQMKLEQQMAETAS
KKTE
>A2QRA3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Aspergillus niger (strain CBS 513.88 / FGSC A1513)|TrEMBL
MSTDRKTVLITGCSDGGIGAALAETFHDHRYHVFATVRTPSKAPKSLINSPNATVLTLDV
LDSTSISDAVEKVTKATGGKLDVLVNNSGGSIILPALDTSIEDGKKLFDLNFWAPLAVTQ
AFAPLLIRSKGCLVNNTSVNGALPFVFMSMYNSSKAAFMSASETWRMELAPLGVRTITLM
TGGVKTKFFDNYVPRQVPENSYYIGAKDAVQKMGDGSLQDSGIDRYSYASKVFQAVERKV
SGKLWVGGGAVPAKWALWLLPQWGVVGILLLFAAEYLCGIDEDDVLNALVGFDDEKNVSC
VWNNRSWGEERRLKSYTSCATVMAA
>A0A0H3J1P6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Clostridium pasteurianum DSM 525 = ATCC 6013|TrEMBL
MKTSDTVLITGASSGIGFELAKVFASHTYNIVLVSRSVEKMKKLAKELTNKYKIKVHVIA
QDLSKTGAAQELFHEVIDRNLQVDILVNNAGIGAVGLFHHMKMEKDIEMLQLNIVTLTEI
TKLFSKKMIERGYGKILNVASTGSFAPGPFIAVYYATKAYVLSFSEAIYRELKPYNITVS
TLCPGATRTNFAKSAGRKNSSIAMMPDKVARIAYKGLKNNKKLIIPGLANKILVMLPRNF
ISNMVFKYQKKLAKLSK
>Q9GME2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Callithrix jacchus|TrEMBL
MACTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATMRDLKTQGQLWEAARAQGCPRDSL
ETLQLDVRDSKSVANAQACVTEGRVDILVCNAGQGLLGPLEALGEDAVGSVLDVNVAGTV
RMLQAFLPEMKRRGSGRVLVTGSMGGLMGLPFNDVYCASKFALEGLCESLAVLLPPFGVH
VSLIECGPVHTPFMQKVLGGPGWMLDRTDTRTRRLFHQYLQHNKEIFREAAQHPEEVVEV
FLTALRAPKPALRYFTTERFLPLQQMRLDDPSGSSYVAAMHRNVFPKEPAEAEAGAGAGG
VGDPELGDTLAAPQ
>B7PY26|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MTTKSLGGPLRGRLAVVTGGGGVIGKAICDVLAEKAAQVIVADINLATAEEGTFLMTKAA
VQDMLAGGVTEGVVVNVSSLVAKTGWKGVCSYAASEAGIIGLTKTAALDLADKGIRCNAV
LPGLTETPDQRFLTEEQKQDISSRVPLGRLAQPTEVADVVVFLCSPESSYMTGTAVEVTG
GSAF
>H3D2B5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Tetraodon nigroviridis|TrEMBL
SSGSVRTMDAKVVVITGCSSGIGLSLAVRLASDPQKAFKVYATMRNLSKKERLLESVKGL
HKDTLDILQMDVTSQQSILEATARIVEKRIDVLVCNAGVGLMGPLEVQSLETMREVLEVN
LLGTLQTIQAFLPDMKARGKGHILVTGSTGGLHGLPFNEVYCASKFAVEGACESLAILLQ
HFNIHVSLIECGPVNTDFLANLQKAEVEDVCQNLDQQTLRLYEKYLQHCDSVFQNSAQDT
EDIVKVFQDAIRSPNPAFRYFTSDVMAPLTNLKVTEPDGSRYIRTMSKVIFSTEEK
>F4C2N7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sphingobacterium sp. (strain 21)|TrEMBL
MNTILITGASAGIGKATVRKFANHGWNVIATMRSPEKEQELTQLDNVLVVRLDVEDIGSI
KDAIGSGIERFGKIDVLVNNAGILVIGAFELATEEQVKKQFDVNFFGVLAVTKAILPHFR
ANRSGTIINISSQGGLVGFPTMSLYHASKFALEGFSEAISHELLAQNILVKLIEPGSTAT
NNWGSFIFAKDEAIVDYDAVSKETLDNWTKYDTDPSAPEDIANAIFLAANDKTDKLRYMV
GKDTELYYAMRQKGDREIINYLRQRFIPQVMARRDDQKTS
>G8NTH3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)|TrEMBL
MADKTILITGVSSGLGLALAQEALAQGWTVVGTVRNEEAARNFTATAPGKAFARVLDVTE
YARIPEVVAEVEKTIGGIEVLVNNAGYGMEGPIEESSMEEIRRQFEVNVFGALAVTQAVL
PFMRQRRSGRILNITSMGGLITFPGVGIYHGSKFALEGLSETLGKEVRGFGIFVTAVAPG
GFRTDWAGRSLSRAPRTIPDYDEMFEPQREARQQRNGKQSGDPVKAAKAMLTILADPNPP
AHLLLGPDAVKLVEEKLDSLKAEIEAYRSLSISTDFDAI
>A0A8C8YR91|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Prolemur simus|TrEMBL
MERTVVLITGCSSGIGRHLALRLASDPSRSFKVYATLRDLRAQGPLWEEARARGCPPDSL
ETLQLDVRDSDSVAAARAHVTEGRVDVLVCNAGRGLLGPLEAHAAGAVSSVLDVNVAGTV
RTLQAFLPDMKRRRSGRVLVTGSMGGLMGLPFNAVYCASKFALEGLCESLAVLLPPFGIH
VSLIECGPVRTAFQDKLEGGPGGVLDCTDAQTRHLFSLYQRHCEQVFREAAQDPEEVTEV
FLTALRAPRPALRYFSTERFLPLARLRLEDPSGCSYVAAMQRAVFADEPAEAGAEAGSPE
LGAPPAAPQ
>A0A378L784|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Legionella steigerwaltii|TrEMBL
MKAQAQEHQDHLAHRALALKDTHQVHQGTHKVLVFRHRFSKEHPYVCGIYKNIIAKGKKM
KVAAITGAANGIGLALSQFHLQRGNTVVMVDKDSIKLKQEVERLLTLFPGKILEIPCDVT
QPNEVALLVEQIESQLGRIDWIYNNAGIIGQLAPIWDLCPEHIQKVMDVNLYGMIHIIQE
FTPFLFRQTFRSHIINIASLYALCTGSQTASYAMSKHAVLALSESLYFDLVRLEKPVDVS
VVFPSFTDTALLSHTTSTNSSFHEALKSLLSHSRSAIDIAEHIVHEVEQKKFYIFPDKEV
KGYCEERTQAMILQEMPHVTNIEKLMCALIKRQESRN
>F1QUP2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Danio rerio|TrEMBL
MEQKVVLITGCSSGIGLSLAVHLASNPAKAYKVYATMRNLDKKQRLLESVRGLHKDTLDI
LQMDVTDQQSILDAQRNVSEGRIDILVCNAGVGLMGPLETHSLDTIRAILDVNLLGTIRT
IQTFLPDMKKKRHGRILVTGSMGGLQGLPFNEVYCASKFAIEGACESLAILLQHFNIHIS
LIECGPVNTDFLMNLKRTEPGDKVLEVDAHTRSLYDQYLQHCQSVFQNAAQDTEDIIQVY
LEAMEAQTPFLRYYTNRALLPMSSLKLTSMDGSQYIRAMSKLIFSSPGTDAQK
>A0A0G2QMF6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Felis catus|TrEMBL
DRTVVLITGCSSGIGLHLALRLASDPSRRFKVYATLRDLRAQGPLREAAQSRGCPPGSLE
MLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLEVQEAGAVGSVLDVNVAGTVR
TLQAFLPDMKRRRSGRVLVTGSMGGLMGLPFNAVYCASKFAIEGLCESLAVLLPPFGVHV
SLIECGPVRTAFQEKLEGGPGGALDGADAETRDLFSRYQRHLERIFHEAAQDPEEVTEVF
LAALRAPRPALR
>A0A3P8YU67|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Esox lucius|TrEMBL
MEDNENIPTGTGRQHNPDRFPHHVISHPRSYLRNRPMEQIVVLITGCSSGIGLSLAVRLA
SDPAKTYKVYATMRNLAKKERLLDCVKGLHKDTLEILQMDVTDQQSILDARHRVTENRVD
ILVCNAGVGLMGPLEAQALDTMRQILEVNVLGTISTIQAFLPGMKARGHGRILVTGSLGG
LQGLPFNEVYCASKFAVEGVCESLAVLLQHFNIHVSLVECGPVNTDFLDNLQTAKPGEAA
LQRVDEHTRSLYHTYLKHCGMVFQNAAQDTDDVVKIFLEAIQSASPAFRYYSSDALLPLT
SPKISAPDGLQYIRTMSKIIFSTNEKEEQK
>A0A8C4LMZ4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Equus asinus asinus|TrEMBL
MDRTIVLITGCSSGIGLHLALRLASDPSRSFKVYATLRDLTAQGPLWEMARARGCPPGSL
ETLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLELHPAGAVASVLDANVAGTV
RTIQAFLPDMKRRRSGRILVTGSMGGLMGLPFNAIYCASKFAIEGLCESLAVLLQPFGVH
VSLIECGPVHTAFQEKLEGGPGGALDGADADTRDLFSRYLRHCEQMYREAAQDPEAVTEV
FLTALRAPRPALRYFSTERFLPLVQLRLSDPSGRSYVAAMHSAVFADEPAQDPDGARAEA
RDGEAREP
>A0A8C3WPS0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Catagonus wagneri|TrEMBL
MDRTVVLITGCSSGIGLHLALHLASDPSQSFKVYATLRDLTAQGPLLEAAQARGCPPGSL
ETLQLDVRDADSIAAARTRVTEGRVDVLVCNAGRGLVGPLEAHNEGAVDSVLDVNLAGTV
RMLQAFLPDMKRRRSGRILVTGSVGGLMALPFNAVYCASKFAVEGLCESLAVMLQRFGVY
VSVIECGPVRTAFPEKLEGGLGGILDRTDPETRDLFSRYRRHLEHMLVEATQDPEEVVEV
FLQALRAPRPALRYFSTERFHPLIKLRFSDLSGSSYVAAVHQRVFGDQATEGFEGTDCGE
AEAGAGELGAPLATPQ
>H0SS77|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bradyrhizobium sp. (strain ORS 375)|TrEMBL
MNHSTQPHTIGHLRPVADNVWIVDAGRISAAGLPLPVRMTVIRLSSGDLLLHSPTRFSHA
LREELEQLGPIKYLLAPNVAHWMFLPDWQAALPNARVYAAPGLSERQQVRRSGLRIDREL
TDVTPDEWSEDLQLVLVTAPLFSEVAVFHRPSRTLVLTDLVQNLAPEGLGVLPRAAAHLL
GITAPDGKAPAYLRGLLRLGGRAVQLAAARLIALAPERVIFAHGRWFETGGTTQLRRAFG
WLLDRSPEARRLIRDLKGKRVVITGASSGIGRAAALALAREGASLVLAARREAVLKDVAA
ECEALGGRAIAVGTDVTDAAAVQHLAEQAVQTFGGIDVWINNAGTGVFGAYQDADLALHR
KTIEVNLLGTMNGAYAVLPVFLRQRQGTLINNISLGGWAPTPFAAAYTASKFGLRGFSAS
LRQELAAHNDIHVCSVFPAMVDTPGFVHGANVSGRNLDPGPLLYRPEDVAETFVQLIHAP
RDEVAVGWPARLGQISYALARFPTERLMSSAFRFLLARAKGAPRSSGAVLAPIAAGTAVS
GGWLGRKKLPPAGQLSKIGVAVGLGGLALMLIARGRGRHSTPRVRSHR
>A0A812DU64|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Sepia pharaonis|TrEMBL
MHEEFINFIRYYLGPTTEYFSCLGFIIYALAMCRIMTSVLTLATQSLFSRNLGWMSRLTY
LGEWAVITGSTDGIGKAYAEELAALGLKIILISRSPEKLAAVAKEIEEAHKVEVRTIAVD
FSDNESIYNKIKNELKGLDISILVNNVGMSYPHPEYFVEIPNRTETLSSLIKLNVVAMTM
MTSIVLPDMVKKNCGVIVNVSSASAAGPCPLLTAYSACKAYVKYFSEGLSAEYSDKGVVI
QCLMPFYVTTKMSKLRKSSAMVPTPTAYVKSSLSSLGISSCSFGYWSHNFLGWFTKTLPR
FFLTCKKRKYNSVFPNLMKETGFSYWFKYFTCRLWGGMVLNWISFMMLVTLTISVLASS
>C5QNV0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Staphylococcus caprae M23864:W1|TrEMBL
MNKKIVLITGASTGLGYETAILLAKQGYKVYATMRNLNKQDTLLQIAQENNLDIIIQQLD
VTDIESIQTTVKRILKNEEKIDILINNAGAGFVKTTEHASDDEIMWQLNLNLMGVIRMTK
AVLPSMRARREGHIINISSVGGLVGQPFNEIYCATKFGVEGYTEALSSYVQPKFNVKFSV
IEPGGIQSEFTNNVMAQLDSTGGIQSDEYKPILNTYLNGLKKNYGPGSSQTSNEVAQVIL
DTIENEEPSIRTRTSPWSETFTELKTKADPTGKIQQQRVAKLLGE
>A0A8B9X1K3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bos mutus grunniens|TrEMBL
MDRTVVLITGCSSGIGLHLALRLASDPSQSFKVYATLRDLASQGPLLEAAQSRGCLPGSL
ETLQLDVRDADSIAAAQARVTEGRVDVLVCNAGRGLVGPLEAHKEGSVDAVLDVNLTGTV
RMLQAFLPDMKRRHSGRILVTGSIGGLMALPFNAVYCASKFALEGLCESLAILLQPFGVH
VSLIECGPVHTPFPEKVEGGLGGMLDRADVETRDLFNRYRRHCERVIREAGQDPEEVVEV
FLQALRAPRPALRYFTTERFLPLVQLRFSDPSGSSYVAAAHKSAFHDKAAEGSDGAGAEA
EAGKLEASELRAPLAPQ
>G8TPH9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Niastella koreensis (strain DSM 17620 / KACC 11465 / NBRC 106392 / GR20-10)|TrEMBL
MSKIIFITGASKGFGKLWAEAFLKRGDKVAATARNLTALNELAATYGDNVLPLQLDVNNR
TEVFAAVNKIEKHFGRIDVLINNAGNGVFGTTEETTEAQARYQMETNFFGSLWVVQAVLP
IFRKQKSGHIIQTSSYLGITTLPLLGVYNASKFAVEGLIESIAKETAHLGIKTTLIEPNG
YATDWAGASATRTASDIEDYAPVRAAFAKGSENPTFWGKPEATVAPVLQVADNNNPPQRL
LLGTVAYNTVQQVYTQRLKEVEAWKEVSIAAQGH
>F8AWL0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Candidatus Frankia datiscae|TrEMBL
MRRRTVVSAGVPLAVYEQGNPAGPTVLLVHGYPDTHWVWDDVAAALAADGHHVVRYDVRG
AGASGAAKGACGYRLPQLADDLFAVADAVSPHRAVHLAAHDWGSIQAWEAVTDPRAAGRI
ASYTSLSGPCLDHVGHWARRRLARPTPRHLGQLLTQAAHSWYIGVFHLPLLAPAVWRLGL
AARWGYVLASTEGVIPRTSHPQPTLATDAVHGIALYRANMLPHLLRPRQRPTAVPVQLIT
LARDRYVSPALGDDLDRWVPHLWRRTLTAGHWSALLEKGPTVAQMIKEIAAHADGAPAAP
ALERAAVSSRERAAGPRRPQRPRLRWCRGPGLERAAFAGKLAVVTGGGSGIGRATALAFA
EHGAAVVVCDLDLASAERTVELTRLLGAPAAHAYRVDVADSAAVDTFAREVAAAHGVPDI
VVNNAGVGHGGTFLQTTEKEWQHILEVNLGGVVHGCRAFATLMVERGEGGHIVNVSSAAA
YLPSKVLAAYATSKAAVYMLSDCLRAELAPAGIGVSTICPGLVNTNITRTSTFSGRSADG
LDATRDRFAALYARRNFPPEKVAWQILRAVRENRAVVPVTVEARAGRVLSRLSPALTRAA
ARIDID
>A0A1Z5JB84|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Fistulifera solaris|TrEMBL
MTSSWLQLAQKTAIVTGAGSGIGAMGYTVARSLLNQQCRVIQVDRDEASMQHITKDASVV
QCDVSQEDQVRNVFVQSDNPSILINCAGITRDGWISNLSNDDWDSVLDINLKGTFLMCRE
FIRLQNERLKQGEDRPACSIVNVGSVVSELGNLGQTNYAASKGGVLGLTRALAKEVARSH
IRVNAVVPGFIDTPMAQQVPVHVQEQIRNQIPLGRFGKPEEVADLILFLASPRSSYITGE
CIKVSGMISL
>A0A2K5UR13|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Macaca fascicularis|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARARGCPLGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEAVGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVTEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVAAMHRHVFGDDPAEAEAGAGPGA
GAGPSEVGDPELGDPPATPQ
>G6FAR4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Lactococcus lactis subsp. lactis CNCM I-1631|TrEMBL
MKKDEVWLVTGSSTGFGRALVEELIAQDYKVVATARQLSTLSELPDKENILKISLDVTKG
DSIQKAVAETIAKFGRIDVLVNNAGFGYFGVMEESDQSAVRKIMDTNFWGANI
>A0A5Q4ZPC4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Paraburkholderia dioscoreae|TrEMBL
MKTVLITGCSSGFGLEIARYFLDRDWHVIATMRTPREDVLPRSERLRVLALDVTDPESVR
RAVDAAGPIDVLVNNAGIGVLNALEGTSMETAREVFETNTLGTIAMTQAVLPQFRQRKEG
VIVNVTSSVTLRPLHLLSVYTASKAAINAFSESVALELEPFNVRVRVVLPGRAPETRFGE
NAQSRMQGGFPKAYAALAQRVFDHWQQETAITRSLDVAEAVWRAANDPSCPARIAAGADA
IEWANSR
>A0A7R8CTZ9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Lepeophtheirus salmonis|TrEMBL
MEETKVALITGASSGIGAAVLRRLASKGFIVVGCARRVELIEEIASEFPSDKFPETLRIV
FANAGCSIDKGLMEGDFTTWRKLMDVNLISPSALTQYAIKYWTDKSPEKGYGKIVYLNSL
SAHVRVFRDILRFYGVTKDALNSLARYWRDEVKEKYPNHSICIGEICPGLVKTDFLGAML
GKDDIKTKHINDYFLTAPFILPEEIADAFEHMISTPKNIQIEDIVIRNTKQVL
>A0A1Y5PEH4|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|uncultured Mycobacterium sp|TrEMBL
MADGFAGKRVFITGAASGIGRATALRLARDCAELYLTDVNADGLEETVADARALGALVPA
HRALDIADYHEVAQFAADIHTHHGAMDIVMNIAGISAWGTVEHLTHQHWRSMIDVNLMGP
IHVIETFLPPMMAAGRGGHLVNVSSAAGLVALPWHAAYSASKFGLRGLSEVLRFDLARHD
IGVSVVVPGAVDTPLVGTVHIAGVDREHPKVQRWVRLFSGHAVTPEKVAENILTGITKNR
FLIYTSSDIRALYAFKRLAWWPYSVAMRRVNVFFTRALRPRSATFTPPG
>K9PRU2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Calothrix sp. PCC 7507|TrEMBL
MPKTVLITGTSSGIGKLTAIYFAQQGWNVAATMRNPGNSQDLSSFSNLKLYSLDVTDNNS
IQKAIASAIQDFGQIDVLVNNAGFGVDGVFEAMTDEIIEQQFNTNVFGLMRVTRAIIPHL
RAKGGGTIIQIASMGGRITFPLYSIYHSSKWAVEGFSEALHYELEPFNIKIKIIEPGAIK
TEFYGSSRQFITGDNLRMYQSLVDTVEKVSQQAGKNGEPPELVAQVIFQAACDRTRKMRY
AVGKPAPLLLRLRKLLPDSWYFSLIKRSYKIYRITI
>G0QS54|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ichthyophthirius multifiliis (strain G5)|TrEMBL
MYQICSTIGLLQLSYQAYNFIDYVNRYYFTTPIPLKDQFPQKYALITGGTQGLGYGYAEE
LARRGYNIILASRSEDQIQKTITDQNQII
>A4YXG7|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bradyrhizobium sp. (strain ORS 278)|TrEMBL
MASGELLLHSPIRFSDALREELERLGPIKYLLAPNVAHWMFLPDWQAALPNAHVYAVPGL
SERQQVRRSGLRIDRELTDVAPDEWSEELQLVLITAPLFSEVAVFHRPSRTLVLTDLVQN
LAPEGLGVLPRMAARLLGITAPDGKAPAYLRWLLRLGGRAAQLAAARLIALAPERVIFAH
GRWFETGGTTQLRRALGWLLDGSPEARRLMRDLRGKRVVITGASSGIGRATALALAREGA
SLVLAARRENVLKDVAAECETLGGQAIAVGTDVTDADAVRRLAEQAVQSFGGIDVWINNA
GTGVFGAYQDADLALHRKTIEVNLLGTMNGAYAALPVFLRQRRGTLINNISLGGWAPTPF
AAAYTASKFGLRGFSASLRQELAAHQDIHVCSVFPAMVDTPGFVHGANVSGRNLDPGPLL
YRPEDVAETFVQLIHAPRDEVAVGWPARLGQISYALARLPTERLMSTTFRFLLSRAKVAP
RSSGAVLAPIAAGTAVSGGWLGRKKLPPAGQLSKIGLAVGLGGLALMLIARSRSGRPAPR
ARAHR
>B7QN87|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Ixodes scapularis|TrEMBL
MGVIASYEGDHQAIYVDVSNSTAVNNLFEEIESSFSERKVSVVVNSAGIMGTLALIQETS
DADFDDVIGTNLRKLVEEESYFMV
>A0A3B5B469|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Stegastes partitus|TrEMBL
MDKKVVLITGCSSGIGLSLAVRLASDPDKSFKVYATMRNLAKKERLLECVKGLHKDTLDI
LQMDVTDRQSILDARDRVVEKRVDILVCNAGVGLMGPLEMQSLDSMRQILEVNLLGTVQT
IQAFLSEMKAQGQGRILVTGSTGGLHGLPFNEVYCASKFAIEGACESLAVLLQHFNIHVS
LIECGPVNTDFMANLQKVELEDASLQQVDIQTLSLYEKYLQHCSDIFQNAAQDTEDIVKV
FLDAIQSPSPAFRYFTNSVVPPLTKLKVTEPDGSQYISAMSKLIFSTEEQ
>H2QD23|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Pan troglodytes|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG
GAGPSAVGDPELGDPPAAPQ
>X8BK37|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mycobacterium xenopi 3993|TrEMBL
MREIKSAGGEAIACTESVATPTGGAAIIAAAFERYGRLDILIHNAGIVRSRSLQQMSYED
FDAVLDVHLRGAFHVVRPAFPHMCAAGYGRIVLTSSIGGLYGNHGVANYAAAKAG
>A0A4W5N035|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Hucho hucho|TrEMBL
MEQTVVLITGCSSGIGLSLAVRLASDPAKMYKVYATMRNLAKKERLLDCVKGLHKDTLDI
LQMDITDQRSILDARDRVREKRVNILVCNAGVGLMGPLEAQSLATMRQILEVNLLGTIST
IQAFLPGMKAQGHGRILVTGSIGGLQGLPFNEVYCASKFAVEGACESLAILLQHFNIHVS
LIECGPVNTDFLDNLQRAEPGDSSLQQVDAHTRSLYDTYLQHCGMVFQNAAQDTEDIVKV
FLDAIQSSNPAFRYYTNNALIPLSSPKISALDGSQYIRTMSKIIFSTNGKGEQK
>Q399T5|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MKTVLITGCSSGFGLEIARYFLARDWQVVATMRTPREDVLPPSAHLRVLALDVTNPDSIR
AAIDAAGPIDVLVNNAGFGAAAPAELMPIDTVRALFETNTIGTIAVTEAVLPQLRRRGAG
VVVNVTSSVTLKVLPLLAAYRASKAAVNAYTESVALELEPFGVRARLVLPGRAPDTRFAD
NARAHMHGFEHEAYAEFVAATFARLVDESAPITHAQDVAEAVWRAATDPSCPMRIPAGAD
AVAWAAEAG
>L7JXW2|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Trachipleistophora hominis|TrEMBL
MINKLIYSISQRKYVPFIVKLVIVTFLSYLFNIVHFYRMRSVEPKKVKHKFCVITGGTRG
IGRELVDLLVLKGYEVMVLGRTKVNRSKVVHYGLDLNNLQEVAQFKMDKDIDLLVMNAGI
LTGKTDGIDLNFKINYLAHYILYNNLRSNLKNARVVLTSSCVMLSVDTFDPYRPSFFSFR
KYCESKLCVFLLGKYISRNLQTVVVHPGVVNTTLFNENSLLNFFISKISYPFLNSTDEAA
NVLMNACQFEMSREKKIIFLYGFEEMKIPCSINRKNEKKLMKITKHFLVKNGIER
>A0A396GNT9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Medicago truncatula|TrEMBL
MLHIKYLSSQEGTRSFISDVKAGISTIKRIVRENRVLLVLDDVDHVNQLDALIGKREWFH
EGSCIIITTRDTTVLPEKHVNELYEVTELYPEEAWKNELVGRMGRCS
>A0A0G2SJM3|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Fimbriaphyllia ancora|TrEMBL
MSAAGSPNLRYNGKVTIVTGGSKGIGEGIVREFVKAGAKVVFCARGVKEGKNLEKEVNET
GPGESYYIKCDVSKEEDIKNLVEKTVEQYGCIDCLINNAGWHPPMKTVDQTSIDEFKDLL
NLNLVNYFIFCKYSLPYLRKTKGNIINMSSLVAQIGQPGAVAYVASKGGITSMTRALAVD
EAKYGVRVNSLSPGNIWTPLWDDLAHSSGNFEKSKKDGEEAQLLGRMGTLEESGQACLYL
AAEATFTTGIDMLLSGGAELTYGKKTQVNNA
>A0A1Z3FWF0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rhodococcus sp. P14|TrEMBL
MNTEFSGKTVAVTGAGSGMGRAEAQLLASLGAHVWVADIDSTAGEAVIDQIRDKGGAADF
HRLDVTDPDAWSRFAEVIDAADGNLDGLVNNAGVSFRYGIEDTSVEDWRRVMAINLDSVF
YGMRACAPLLKCNGGGSIVNISSIAGMLGYFAAAYGASKWGVRGLSKVGALEFAEHHVRV
NSVHPGLVETPLLTSGTTEFVDESLKSVPAGRSADPDEVAETVAFLLSDRSTYITGTEIV
IDGGLTSGGLYHRITRELG
>A3QRK1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Equus caballus|TrEMBL
MDRTIVLITGCSSGIGLHLALRLASDPSRSFKVYATLRDLTAQGPLWEMARARGCPPGSL
ETLQLDVRDADSVAAARARVTEGRVDVLVCNAGRGLLGPLELHPAGAVASVLDANVAGTV
RTIQAFLPDMKRRRSGRILVTGSMGGLMGLPFNAIYCASKFAIEGLCESLAVLLQPFGVH
VSLIECGPVHTAFQEKLEGGPGGALDGADADTRDLFSRYLRHCEQMYREVAQDPEAVTEV
FLTALRAPRPALRYFSTERFLPLVQLRLSDPSGRSYVAAMHSAVFADEPAQDPDGARAEA
RDGEAGEP
>C9JRZ8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MATFVELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQ
EKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGD
DFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKP
VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK
HKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD
FKEFSHLEDFPFDAEY
>H0YSD6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Taeniopygia guttata|TrEMBL
MGLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGYGKSSSAADKVVDEI
IAKGGRAVPNYDSVEDGEKLVKAALEAFGRIDIVINNAGILRDRSFVRISDEDWDIIHRI
HLRGSFLVTRAAWNHMKNQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTIAIEG
RKYNIHCNTIAPTAGSRLTQTVMPQDLVDAFKPEYVAPLVVWLCHESCAENGSLFEVGAG
WIGKLRWERSLGAIVRGKNQPMTPEAVRDKWEKVCDFDNASKPRTIQESISVLSDALSQI
ESQGNVSMNSTSSGSVVSSSVDTASIVGRKLGTNVYKYTHLEPILYALGVGMSTKDPDHL
KFLFEGSEEFCCLPSFGVIPAQTSMFDGVPSLSGLNIDLARMLHGEQYLELYKPLPTSGE
LRSVSTVADILDKGSGAVLLIDVNTYCGKDLVCYNQFSLFFVGAGGFGGKRTTEKAKLTA
VPPKRPPDAVISDVTTADQAALYRLSGDWNPLHVDPSFAALGGFEKPILHGLCTFGFAAR
NVLKQFAKNDVNRFKAIKVRFAKPVYPGETLQTEMWKEGNRIHFQTKIKETGEVAIAGGY
VDIVPALEKPSAREPLMVRLQSNLVFEEIGRRVKEMGNELVKKVNAVFQWDITKDGNTAM
QWTIDLKNGSGAVYQGPARNSVDTTFTLSDEDFMDVVQQKITPQKAFFSGKLKVKGNIML
SQKLEMILKDYAKL
>K7S9E9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Nucella lapillus|TrEMBL
MASLATMLQGYFGKSADIFTVIGAVTTAFFAFKATSSVLNGLFSYVLSGALGLSLNLENA
GSWAVVTGCTDGIGKAYAEQLAKRGLNIVLISRTRSKLDELARDIESRFKVKTKVIAADF
TRSDIYDMIPQELDGLDIGTLVNNVGMGYDHPEFFDQLENRDQVIMNIINCNSTSVAMMT
SLVLPGMVSKKRGVIINIASAAGNRPTPLLTLYSATKSFVDFFSRALQHEYGPKGITVQV
VLPYFVATKMSKIRKGGVFAPYPNDFVRSALHTVGLQSRTFGCWSHALQDKVAALLPTSV
TMQMMEKARAKSLKKKANKSE
>O93874|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Cochliobolus lunatus|TrEMBL
MPHVENASETYIPGRLDGKVALVTGSGRGIGAAVAVHLGRLGAKVVVNYANSTKDAEKVV
SEIKALGSDAIAIKADIRQVPEIVKLFDQAVAHFGHLDIAVSNSGVVSFGHLKDVTEEEF
DRVFSLNTRGQFFVAREAYRHLTEGGRIVLTSSNTSKDFSVPKHSLYSGSKGAVDSFVRI
FSKDCGDKKITVNAVAPGGTVTDMFHEVSHHYIPNGTSYTAEQRQQMAAHASPLHRNGWP
QDVANVVGFLVSKEGEWVNGKVLTLDGGAA
>P14016|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Bacillus subtilis (strain 168)|Swiss-Prot
MSEYREIITKAVVAKGRKFTQCTNTISPEKKPSSILGGWIINHKYDAEKIGKTVEIEGYY
DINVWYSYADNTKTEVVTERVKYVDVIKLRYRDNNYLDDEHEVIAKVLQQPNCLEVTISP
NGNKIVVQAEREFLAEVVGETKVVVEVNPDWEEDDEEDWEDELDEELEDINPEFLVGDPE
E
>Q0VGQ1|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Mus musculus|TrEMBL
MECAPPAAGFLYWVGASTIAYLALRASYSLFRAFQVWCVGNEALVGPRLGEWAVVTGGTD
GIGKAYAEELAKRGMKIVLISRSQDKLNQVSNNIKEKFNVETRTIAVDFSLDDIYDKIKT
GLSGLEIGVLVNNVGMSYEYPEYFLEIPDLDNTIKKLININVLSVCKVTRLVLPGMVERS
KGVILNISSASGMLPVPLLTIYSATKAFVDFFSQCLHEEYKSKGIFVQSVMPYLVATKLA
KIQKPTLDKPSAETFVKSAIKTVGLQTRTTGYVIHSLMGSINSIMPRWMYFKIIMGFSKS
LRNRYLKKRKKN
>Q4JK77|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Macaca fascicularis|TrEMBL
MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARARGCPLGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAGLGLLGPLEAVGEDAVASVLDVNVVGTV
RVLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH
LSLIECGTVHTAFMEKVLGSPDEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVTEV
FLTALRAPKPTLRYFTTERFLPLLRMRLDDPSGSNYVAAMHRHVFGDDPAEAEAGAGPGA
GAGPSEVGDPELGDPPATPQ
>Q5MGS6|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|TrEMBL
MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV
QVDVSNLQSFFRASKELKQSCRFQRLDRIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFS
TAEGLLTQGDKITADGLQEVFETDVFGHFILIRELEPLLCHNDNPSQLIWTSSRNARKSN
FSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFQPAASLFCKCIHFDTI
>Q9N0M8|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Callithrix jacchus|TrEMBL
ASSGIGLALCKRLLVEDDELHLCLACRNMSKAEAVRAALLASHPTAEVTVVQVDVSNLQS
VFQASKELKQRFQRFDCIYLNAGIMPNPHLNIKALFSGLFSRNVIHMFSTAEGLLTQDDK
ITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRNARKSNFSLEDFQHSKG
KEPYSSSKYATDLLSVALNRNFNQQGLYSNVVCPGTALTNLTYGVLPPFIWTLLMPAILL
MRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTGFGRNYITTQKMDLDEDTA
EKFYQKLLELEKHVRVTVQKTDN
>A3DDY9|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372)|TrEMBL
MQLKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVA
KGDVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSAYL
CTKAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYC
NAVAPGIIKTDMTDVLPDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNYITGQVIN
IDGGLVM
>P51659|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Homo sapiens|Swiss-Prot
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI
GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
MLSQKLQMILKDYAKL
>P97852|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Rattus norvegicus|Swiss-Prot
MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE
EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ
RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI
EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH
KIDSEGISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDL
KFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRSG
ELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAA
VAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFSA
RHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNA
YVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVA
AKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNIM
LSQKLQMILKDYAKL
>Q9VXJ0|17beta-estradiol 17-dehydrogenase|EC 1.1.1.62|Drosophila melanogaster|Swiss-Prot
MSSSDGKLRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADI
VVDEIRKAGGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWN
LVNDVHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANT
VAIEGARNNVLCNVIVPTAASRMTEGILPDILFNELKPKLIAPVVAYLCHESCEDNGSYI
ESAAGWATKLHMVRGKGAVLRPSLDDPVTIEYVKDVWSNVTDMSKAKHLGAIAEASGTLL
EVLEKLKEGGGDAIEDAFEFNSKELITYALGIGASVKNAKDMRFLYENDADFAAIPTFFV
LPGLLLQMSTDKLLSKALPNSQVDFSNILHGEQYLEIVDDLPTSGTLLTNGKVFDVMDKG
SGAVVVTNSESFDESGRLLVRNQSTTFIVGAGKFGGKKDPIAGVVPLQPAPNRQPDATVQ
YTTSEDQAALYRLSGDKNPLHIDPQMALLAGFKTPILHGLCTLGFSVRAVLAQFADNNPA
LFKAVKVRFSGPVIPGQTLRVDLWKQGTRINFRTVVVETGKEVISGAYVDLKSSQAKL