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Sequence of CATD_DICDI

EC Number:3.4.23.5

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
cathepsin D
O76856
Dictyostelium discoideum
383
41121
Reaction
Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His bond in B chain of insulin

General information:

Sequence
show sequence in fasta format
  0 MKLLILTLFL ATIVLAQALT VPLNFHQASR ESRRRVPQKW SNRLSALNAG TTIPISDFED
 60 AQYYGAITIG TPGQAFKVVF DTGSSNLWIP SKKCPITVVA CDLHNKYNSG ASSTYVANGT
120 DFTIQYGSGA MSGFVSQDSV TVGSLTVKDQ LFAEATAEPG IAFDFAKFDG ILGLAFQSIS
180 VNSIPPVFYN MLSQGLVSST LFSFWLSRTP GANGGELSFG SIDNTKYTGD ITYVPLTNET
240 YWEFVMDDFA IDGQSAGFCG TTCHAICDSG TSLIAGPMAD ITALNEKLGA VILNGEGVFS
300 DCSVINTLPN VTITVAGREF VLTPKEYVLE VTEFGKTECL SGFMGIELNM GNFWILGDVF
360 ISAYYTVFDF GNKQVGFATA IQG
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
296550
Journet A.,Chapel A.,Jehan S.,Adessi C.,Freeze H.,Klein G.,Garin J.
Characterization of Dictyostelium discoideum cathepsin D. Molecular cloning, gene disruption, endo-lysosomal localization and sugar modifications.
J. Cell Sci.
112
3833-3843
1999
296551
Eichinger L.,Pachebat J.A.,Gloeckner G.,Rajandream M.A.,Sucgang R.,Berriman M.,Song J.,Olsen R.,Szafranski K.,Xu Q.,Tunggal B.,Kummerfeld S.,Madera M.,Konfortov B.A.,Rivero F.,Bankier A.T.,Lehmann R.,Hamlin N.,Davies R.,Gaudet P.,Fey P.,Pilcher K.,Chen G.,Saunders D.,Sodergren E.J.,Davis P.,Kerhornou A.,Nie X.,Hall N.,Anjard C.,Hemphill L.,Bason N.,Farbrother P.,Desany B.,Just E.,Morio T.,Rost R.,Churcher C.M.,Cooper J.,Haydock S.,van Driessche N.,Cronin A.,Goodhead I.,Muzny D.M.,Mourier T.,Pain A.,Lu M.,Harper D.,Lindsay R.,Hauser H.,James K.D.,Quiles M.,Madan Babu M.,Saito T.,Buchrieser C.,Wardroper A.,Felder M.,Thangavelu M.,Johnson D.,Knights A.,Loulseged H.,Mungall K.L.,Oliver K.,Price C.,Quail M.A.,Urushihara H.,Hernandez J.,Rabbinowitsch E.,Steffen D.,Sanders M.,Ma J.,Kohara Y.,Sharp S.,Simmonds M.N.,Spiegler S.,Tivey A.,Sugano S.,White B.,Walker D.,Woodward J.R.,Winckler T.,Tanaka Y.,Shaulsky G.,Schleicher M.,Weinstock G.M.,Rosenthal A.,Cox E.C.,Chisholm R.L.,Gibbs R.A.,Loomis W.F.,Platzer M.,Kay R.R.,Williams J.G.,Dear P.H.,Noegel A.A.,Barrell B.G.,Kuspa A.
The genome of the social amoeba Dictyostelium discoideum.
Nature
435
43-57
2005