Sequence of RDH16_MOUSE
EC Number:1.1.1.315
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
11-cis-retinol-[retinal-binding-protein] + NAD+ = 11-cis-retinal-[retinol-binding-protein] + NADH + H+
General information:
Sequence
0 MWLYLVALVG LWTLLRFFRV RQVVSHLQDK YVFITGCDSG FGTLLARQLD RRGMRVLAAC
60 LTEKGAEELR NKTSDRLETV ILDVTKTESI VTATQWVKEH VGNRGLWGLV NNAGISTPSG
120 PNEWMKKQDF AHVLDVNLLG MIEVTLSMLP LVRKARGRVV NVSSVMGRVS LFGGGYCISK
180 YGVEAFSDSL RRELSYFGVK VAIIEPGFFL TGVTSSARLC SNTQMLWDQT SSEIREIYGE
240 KYLASYLKRL NKLDKRCNKD LSGVTDCMEH ALTACHPRTR YSAGWDAKLF YLPLSYLPTF
300 LVDALLYWTS LKPEKAL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
277700
Chai X.,Zhai Y.,Napoli J.L.
cDNA cloning and characterization of a cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase.
J. Biol. Chem.
272
33125-33131
1997
277701
Church D.M.,Goodstadt L.,Hillier L.W.,Zody M.C.,Goldstein S.,She X.,Bult C.J.,Agarwala R.,Cherry J.L.,DiCuccio M.,Hlavina W.,Kapustin Y.,Meric P.,Maglott D.,Birtle Z.,Marques A.C.,Graves T.,Zhou S.,Teague B.,Potamousis K.,Churas C.,Place M.,Herschleb J.,Runnheim R.,Forrest D.,Amos-Landgraf J.,Schwartz D.C.,Cheng Z.,Lindblad-Toh K.,Eichler E.E.,Ponting C.P.
Lineage-specific biology revealed by a finished genome assembly of the mouse.
PLoS Biol.
7
E1000112-E1000112
2009
277703
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
277704
Tryggvason K.,Romert A.,Eriksson U.
Biosynthesis of 9-cis-retinoic acid in vivo. The roles of different retinol dehydrogenases and a structure-activity analysis of microsomal retinol dehydrogenases.
J. Biol. Chem.
276
19253-19258
2001
277705
Zhang M.,Hu P.,Napoli J.L.
Elements in the N-terminal signaling sequence that determine cytosolic topology of short-chain dehydrogenases/reductases. Studies with retinol dehydrogenase type 1 and cis-retinol/androgen dehydrogenase type 1.
J. Biol. Chem.
279
51482-51489
2004
277706
Liden M.,Tryggvason K.,Eriksson U.
The C-terminal region of cis-retinol/androgen dehydrogenase 1 (CRAD1) confers ER localization and in vivo enzymatic function.
Exp. Cell Res.
311
205-217
2005
277707
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
