Sequence of HEXA_DOTSN
EC Number:1.1.1.100
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
3-oxoacyl-[acyl-carrier-protein] reductase
M2YJJ3
Dothistroma septosporum (strain NZE10 / CBS 128990)
1692
183262
Reaction
a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = a 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
General information:
Sequence
0 MGQKTIKRKI QSAERPAEAD VAFLASTQHS KDLCYEYDAP EEVAVEEPVD ETPAPETAPE
60 RPPLSRAKTA AVKPQETAAP TTATIADVPL SAEEIVRALV ARKLKKPILS IPTSKSVKEL
120 CNGKSTLQNE IVGDFHSEFT NLPDRPEDIP LKELVPASQS LMLGRVSSAL LSKLVSSKMP
180 ARFNADAIGK YLASKWGLGP LRSVAVMLFA IAAEPEARLG SVAAAEKYLD DTAAKYAEWA
240 GITLQERSTQ SSAGGGGSSG TVDPTVLAEL TKTNTRLAKR QFQALAEYLQ VDLMKPSSEQ
300 ESEALAVELQ QKLDAWTAEF SEEFLAGVAP TFSEKKSRRY NAWWNAARQD VLALFSGNLQ
360 EDLSRDAAAL EAFLDRLSNR AGESLLAMTR SLSRRNQANA IPGLTDIARR AEKAISSCID
420 RPATAKVHLP ATRPRTTVSD EGDIKFNEVP RPDVSGHAAY ADVLQAKDLN GHPAAARFVS
480 LKSAHSHTDL TNGMLDRIRT ALDSGMSFAG KNILITGAGQ GSIGAEVVRI LLTGGARVIV
540 TTSREPSSTA KYFQQMYEES GAKGSELILT RFNQASAKDC ENLVDHIYDS SGLDRDLDAV
600 LPFAAAPEGG TEIQDVGAKN ELVHRLMLAS VFRMLGRVIK NKRDRSIDCH PTQVLLPLSP
660 NHGTFGGDGM YAESKLGLES LVNRVQSESW SDELAICGVK IGWTRGTGLM NANDIVAEAI
720 EDHGVLTFSV QEMAFNIAML MTPELVDLCE NAPLMADFGG GLSALEDCAK ILSAARTEIN
780 TAADVARAVK AEDDLERAAS RTLPAPSSTS PVAKKSMLRI GFPRLPDFEL ELSPLEHLRD
840 IKDPSETVVV VGFSELGPWG SARLRWEIES KGDFSQVGYM EMAWMMDLIK HVDGPTKNGY
900 YVGWVDSKTG ESVHDAEIEA RYGEVIRKHS GIRFVDPEGS AGYDPSKKEY LHEVAVEEDL
960 PEFEASSATA EAFRLRHGTN VSISPIEGTE NCRVQVKRGA SIKIPKSVPF TWGSVAGQLP
1020 KGWSPKKYGI PEDLIPQLDP VSLYTICCVA EAFYSAGITD PLEIFKYIHL SEIGNFLGSS
1080 MGGALKTRQM YRDIYLDKDI QSDVLQETYL NTTGAWVNML LLGSTGPIKT PMGACATGVE
1140 SIDSAFESIM SDKTRMCIVG GFDDFHEDES YGFSTMKATV NVEEELAKGR LPSEMSRPTA
1200 ESRSGFVEAH GCGVQILCRG DVALEMGLPV YGIIAGSTMA ADKVGRSVPA PGQGILTFAR
1260 ETGQAQLDKS SPSTNTTSRT SSVSLARRGA TVSPLRASLD AWGLTIDDLD VASLHGTSTK
1320 ANDLNEPEVI CKQMDHLGRT PGRPLWAICQ KSVTGHPKAP AAAWMLNGCL QVMDSRTIPA
1380 NRNADNVDPA LQTATHLCFP TRPVRVQDVR AFILTSFGFG QKGGQVVGVA PKYFFATLDE
1440 EVYKDYSVRV TKRSKTADRA YAKALMSNAI VKVQDHSPYE QEDQSRIFMD PLSRITEDAE
1500 TGSYHFDTKD IRNVADVKAR LTRLVRGERL NARPDAASGL AQAARSAQAW IEKQTGGRSS
1560 VDTSTVGIDL VDLSAFSAHE NETFIERNFT EQEKAFAKQS LDQKMAFASR WAAKEAVFKC
1620 LHTQTKGAGA AMKDIEIVKS DNAPKVKLHN DCIKAGRKAG LEDIQLSISH GEDCLIAVAI
1680 GIAGNGPAKY TL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
235588
de Wit P.J.G.M.,van der Burgt A.,Oekmen B.,Stergiopoulos I.,Abd-Elsalam K.A.,Aerts A.L.,Bahkali A.H.,Beenen H.G.,Chettri P.,Cox M.P.,Datema E.,de Vries R.P.,Dhillon B.,Ganley A.R.,Griffiths S.A.,Guo Y.,Hamelin R.C.,Henrissat B.,Kabir M.S.,Jashni M.K.,Kema G.,Klaubauf S.,Lapidus A.,Levasseur A.,Lindquist E.,Mehrabi R.,Ohm R.A.,Owen T.J.,Salamov A.,Schwelm A.,Schijlen E.,Sun H.,van den Burg H.A.,van Ham R.C.H.J.,Zhang S.,Goodwin S.B.,Grigoriev I.V.,Collemare J.,Bradshaw R.E.
The genomes of the fungal plant pathogens Cladosporium fulvum and Dothistroma septosporum reveal adaptation to different hosts and lifestyles but also signatures of common ancestry.
PLoS Genet.
8
E1003088-E1003088
2012
235589
Ohm R.A.,Feau N.,Henrissat B.,Schoch C.L.,Horwitz B.A.,Barry K.W.,Condon B.J.,Copeland A.C.,Dhillon B.,Glaser F.,Hesse C.N.,Kosti I.,LaButti K.,Lindquist E.A.,Lucas S.,Salamov A.A.,Bradshaw R.E.,Ciuffetti L.,Hamelin R.C.,Kema G.H.J.,Lawrence C.,Scott J.A.,Spatafora J.W.,Turgeon B.G.,de Wit P.J.G.M.,Zhong S.,Goodwin S.B.,Grigoriev I.V.
Diverse lifestyles and strategies of plant pathogenesis encoded in the genomes of eighteen Dothideomycetes fungi.
PLoS Pathog.
8
E1003037-E1003037
2012
235590
Bradshaw R.E.,Bhatnagar D.,Ganley R.J.,Gillman C.J.,Monahan B.J.,Seconi J.M.
Dothistroma pini, a forest pathogen, contains homologs of aflatoxin biosynthetic pathway genes.
Appl. Environ. Microbiol.
68
2885-2892
2002
235591
Bradshaw R.E.,Jin H.,Morgan B.S.,Schwelm A.,Teddy O.R.,Young C.A.,Zhang S.
A polyketide synthase gene required for biosynthesis of the aflatoxin-like toxin, dothistromin.
Mycopathologia
161
283-294
2006
235592
Zhang S.,Schwelm A.,Jin H.,Collins L.J.,Bradshaw R.E.
A fragmented aflatoxin-like gene cluster in the forest pathogen Dothistroma septosporum.
Fungal Genet. Biol.
44
1342-1354
2007
235593
Schwelm A.,Bradshaw R.E.
Genetics of dothistromin biosynthesis of Dothistroma septosporum: an update.
Toxins
2
2680-2698
2010
235594
Chettri P.,Ehrlich K.C.,Cary J.W.,Collemare J.,Cox M.P.,Griffiths S.A.,Olson M.A.,de Wit P.J.,Bradshaw R.E.
Dothistromin genes at multiple separate loci are regulated by AflR.
Fungal Genet. Biol.
51
12-20
2013
235595
Bradshaw R.E.,Slot J.C.,Moore G.G.,Chettri P.,de Wit P.J.,Ehrlich K.C.,Ganley A.R.,Olson M.A.,Rokas A.,Carbone I.,Cox M.P.
Fragmentation of an aflatoxin-like gene cluster in a forest pathogen.
New Phytol.
198
525-535
2013
235596
Chettri P.,Ehrlich K.C.,Bradshaw R.E.
Regulation of the aflatoxin-like toxin dothistromin by AflJ.
Fungal Biol.
119
503-508
2015
