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Sequence of NOTN_ASPSM

EC Number:1.1.1.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
alcohol dehydrogenase
E1ACQ9
Aspergillus sp. (strain MF297-2)
339
35912
Reaction
(R)-mevalonate + NAD+ = mevaldate + NADH + H+

General information:

Sequence
show sequence in fasta format
  0 MSLPQTYKRA VFKELGHPLT VEDAPLKLPG PNELLIKVEA CGVCYSDMYS QYNGLGGGFP
 60 IVPGHEIIGK VAVVGSEVRD WNVGQRIGAG WHGGHDGTCK ACKQGYFQMC DSTAVNGATK
120 EGGYAEYTLI RSESAVHIPA NVDAASYAPI LCAGLTVFNS IRNVNIRAGE TVAVQGLGGL
180 GHLAIQYAKR MGYRVVAISR GPEKEAAARE LGADEYIDSN EGDSGEQLAA LGGAALAVTT
240 ASTGEAITPL LKGLGILGKL LVLSFPSNLT LEPTDLLKYG LSVHFWPSGH PSDAEDAVRF
300 AENTNIASVV EKFPLEQAQQ AFESMLSGKV RFRAVITMD
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
214588
Ding Y.,de Wet J.R.,Cavalcoli J.,Li S.,Greshock T.J.,Miller K.A.,Finefield J.M.,Sunderhaus J.D.,McAfoos T.J.,Tsukamoto S.,Williams R.M.,Sherman D.H.
Genome-based characterization of two prenylation steps in the assembly of the stephacidin and notoamide anticancer agents in a marine-derived Aspergillus sp.
J. Am. Chem. Soc.
132
12733-12740
2010
214589
Kato H.,Yoshida T.,Tokue T.,Nojiri Y.,Hirota H.,Ohta T.,Williams R.M.,Tsukamoto S.
Notoamides A-D: prenylated indole alkaloids isolated from a marine-derived fungus, Aspergillus sp.
Angew. Chem. Int. Ed.
46
2254-2256
2007
214590
Li S.,Finefield J.M.,Sunderhaus J.D.,McAfoos T.J.,Williams R.M.,Sherman D.H.
Biochemical characterization of NotB as an FAD-dependent oxidase in the biosynthesis of notoamide indole alkaloids.
J. Am. Chem. Soc.
134
788-791
2012
214591
Li S.,Anand K.,Tran H.,Yu F.,Finefield J.M.,Sunderhaus J.D.,McAfoos T.J.,Tsukamoto S.,Williams R.M.,Sherman D.H.
Comparative analysis of the biosynthetic systems for fungal bicyclo[2.2.2]diazaoctane indole alkaloids: the (+)/(-)-notoamide, paraherquamide and malbrancheamide pathways.
Med. Chem. Commun.
3
987-996
2012