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Sequence of AMPA_ECOLI

EC Number:3.4.11.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
leucyl aminopeptidase
P68767
Escherichia coli (strain K12)
503
54880
Reaction
release of an N-terminal amino acid, Xaa-/-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolysed, but rates on arylamides are exceedingly low
Other sequences found for EC No. 3.4.11.1

General information:

Sequence
show sequence in fasta format
  0 MEFSVKSGSP EKQRSACIVV GVFEPRRLSP IAEQLDKISD GYISALLRRG ELEGKPGQTL
 60 LLHHVPNVLS ERILLIGCGK ERELDERQYK QVIQKTINTL NDTGSMEAVC FLTELHVKGR
120 NNYWKVRQAV ETAKETLYSF DQLKTNKSEP RRPLRKMVFN VPTRRELTSG ERAIQHGLAI
180 AAGIKAAKDL GNMPPNICNA AYLASQARQL ADSYSKNVIT RVIGEQQMKE LGMHSYLAVG
240 QGSQNESLMS VIEYKGNASE DARPIVLVGK GLTFDSGGIS IKPSEGMDEM KYDMCGAAAV
300 YGVMRMVAEL QLPINVIGVL AGCENMPGGR AYRPGDVLTT MSGQTVEVLN TDAEGRLVLC
360 DVLTYVERFE PEAVIDVATL TGACVIALGH HITGLMANHN PLAHELIAAS EQSGDRAWRL
420 PLGDEYQEQL ESNFADMANI GGRPGGAITA GCFLSRFTRK YNWAHLDIAG TAWRSGKAKG
480 ATGRPVALLA QFLLNRAGFN GEE
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
4249
Stirling C.J.,Colloms S.,Collins J.F.,Szatmari G.,Sherratt D.J.
xerB, an Escherichia coli gene required for plasmid ColE1 site-specific recombination, is identical to pepA, encoding aminopeptidase A, a protein with substantial similarity to bovine lens leucine aminopeptidase.
EMBO J.
8
1623-1627
1989
4250
Charlier D.,Hassanzadeh G.,Kholti A.,Gigot D.,Pierard A.,Glansdorff N.
carP, involved in pyrimidine regulation of the Escherichia coli carbamoylphosphate synthetase operon encodes a sequence-specific DNA-binding protein identical to XerB and PepA, also required for resolution of ColEI multimers.
J. Mol. Biol.
250
392-406
1995
4251
Burland V.D.,Plunkett G. III,Sofia H.J.,Daniels D.L.,Blattner F.R.
Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes.
Nucleic Acids Res.
23
2105-2119
1995
4252
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
4253
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
4254
McCulloch R.,Burke M.E.,Sherratt D.J.
Peptidase activity of Escherichia coli aminopeptidase A is not required for its role in Xer site-specific recombination.
Mol. Microbiol.
12
241-251
1994
4255
Hayashi M.,Tabata K.,Yagasaki M.,Yonetani Y.
Effect of multidrug-efflux transporter genes on dipeptide resistance and overproduction in Escherichia coli.
FEMS Microbiol. Lett.
304
12-19
2010
4256
Strater N.,Sherratt D.J.,Colloms S.D.
X-ray structure of aminopeptidase A from Escherichia coli and a model for the nucleoprotein complex in Xer site-specific recombination.
EMBO J.
18
4513-4522
1999