Sequence of CARP1_CANAW
EC Number:3.4.23.24
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Preferential cleavage at the carboxyl of hydrophobic amino acids, but fails to cleave Leu15-Tyr, Tyr16-Leu and Phe24-Phe of insulin B chain. Activates trypsinogen, and degrades keratin
General information:
Sequence
0 MFLKNIFIAL AIALLVDASP AKRSPGFVTL DFDVIKTPVN ATGQEGKVKR QALPVTLNNE
60 HVSYAADITI GSNKQKFNVI VDTGSSDLWV PDASVTCDKP RPGQSADFCK GKGIYTPKSS
120 TTSQNLGTPF YIGYGDGSSS QGTLYKDTVG FGGASITKQV FADITKTSIP QGILGIGYKT
180 NEAAGDYDNV PVTLKNQGVI AKNAYSLYLN SPNAATGQII FGGVDKAKYS GSLIAVPVTS
240 DRELRITLNS LKAVGKNING NIDVLLDSGT TITYLQQDVA QDIIDAFQAE LKSDGQGHTF
300 YVTDCQTSGT VDFNFDNNVK ISVPASEFTA PLSYANGQPY PKCQLLLGIS DANILGDNFL
360 RSAYLVYDLD DDKISLAQVK YTSASNIAAL T
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
201654
Miyasaki S.H.,White T.C.,Agabian N.
A fourth secreted aspartyl proteinase gene (SAP4) and a CARE2 repetitive element are located upstream of the SAP1 gene in Candida albicans.
J. Bacteriol.
176
1702-1710
1994
201655
Butler G.,Rasmussen M.D.,Lin M.F.,Santos M.A.S.,Sakthikumar S.,Munro C.A.,Rheinbay E.,Grabherr M.,Forche A.,Reedy J.L.,Agrafioti I.,Arnaud M.B.,Bates S.,Brown A.J.P.,Brunke S.,Costanzo M.C.,Fitzpatrick D.A.,de Groot P.W.J.,Harris D.,Hoyer L.L.,Hube B.,Klis F.M.,Kodira C.,Lennard N.,Logue M.E.,Martin R.,Neiman A.M.,Nikolaou E.,Quail M.A.,Quinn J.,Santos M.C.,Schmitzberger F.F.,Sherlock G.,Shah P.,Silverstein K.A.T.,Skrzypek M.S.,Soll D.,Staggs R.,Stansfield I.,Stumpf M.P.H.,Sudbery P.E.,Srikantha T.,Zeng Q.,Berman J.,Berriman M.,Heitman J.,Gow N.A.R.,Lorenz M.C.,Birren B.W.,Kellis M.,Cuomo C.A.
Evolution of pathogenicity and sexual reproduction in eight Candida genomes.
Nature
459
657-662
2009
201656
White T.C.,Miyasaki S.H.,Agabian N.
Three distinct secreted aspartyl proteinases in Candida albicans.
J. Bacteriol.
175
6126-6133
1993
201657
White T.C.,Andrews L.E.,Maltby D.,Agabian N.
The 'universal' leucine codon CTG in the secreted aspartyl proteinase 1 (SAP1) gene of Candida albicans encodes a serine in vivo.
J. Bacteriol.
177
2953-2955
1995
