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Sequence of CARP2_CANAW

EC Number:3.4.23.24

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Candidapepsin
C4YMJ3
Candida albicans (strain WO-1)
398
42315
Reaction
Preferential cleavage at the carboxyl of hydrophobic amino acids, but fails to cleave Leu15-Tyr, Tyr16-Leu and Phe24-Phe of insulin B chain. Activates trypsinogen, and degrades keratin

General information:

Sequence
show sequence in fasta format
  0 MFLKNIFIGL AIALLVDATP TTTKRSAGFV ALDFSVVKTP KAFPVTNGQE GKTSKRQAVP
 60 VTLHNEQVTY AADITVGSNN QKLNVIVDTG SSDLWVPDVN VDCQVTYSDQ TADFCKQKGT
120 YDPSGSSASQ DLNTPFKIGY GDGSSSQGTL YKDTVGFGGV SIKNQVLADV DSTSIDQGIL
180 GVGYKTNEAG GSYDNVPVTL KKQGVIAKNA YSLYLNSPDA ATGQIIFGGV DNAKYSGSLI
240 ALPVTSDREL RISLGSVEVS GKTINTDNVD VLLDSGTTIT YLQQDLADQI IKAFNGKLTQ
300 DSNGNSFYEV DCNLSGDVVF NFSKNAKISV PASEFAASLQ GDDGQPYDKC QLLFDVNDAN
360 ILGDNFLRSA YIVYDLDNNE ISLAQVKYTS ASSISALT
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
201622
Butler G.,Rasmussen M.D.,Lin M.F.,Santos M.A.S.,Sakthikumar S.,Munro C.A.,Rheinbay E.,Grabherr M.,Forche A.,Reedy J.L.,Agrafioti I.,Arnaud M.B.,Bates S.,Brown A.J.P.,Brunke S.,Costanzo M.C.,Fitzpatrick D.A.,de Groot P.W.J.,Harris D.,Hoyer L.L.,Hube B.,Klis F.M.,Kodira C.,Lennard N.,Logue M.E.,Martin R.,Neiman A.M.,Nikolaou E.,Quail M.A.,Quinn J.,Santos M.C.,Schmitzberger F.F.,Sherlock G.,Shah P.,Silverstein K.A.T.,Skrzypek M.S.,Soll D.,Staggs R.,Stansfield I.,Stumpf M.P.H.,Sudbery P.E.,Srikantha T.,Zeng Q.,Berman J.,Berriman M.,Heitman J.,Gow N.A.R.,Lorenz M.C.,Birren B.W.,Kellis M.,Cuomo C.A.
Evolution of pathogenicity and sexual reproduction in eight Candida genomes.
Nature
459
657-662
2009
201623
White T.C.,Miyasaki S.H.,Agabian N.
Three distinct secreted aspartyl proteinases in Candida albicans.
J. Bacteriol.
175
6126-6133
1993