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Sequence of CARP3_CANAW

EC Number:3.4.23.24

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Candidapepsin
C4YNQ5
Candida albicans (strain WO-1)
398
42716
Reaction
Preferential cleavage at the carboxyl of hydrophobic amino acids, but fails to cleave Leu15-Tyr, Tyr16-Leu and Phe24-Phe of insulin B chain. Activates trypsinogen, and degrades keratin

General information:

Sequence
show sequence in fasta format
  0 MFLKNIFIAL AIALLADATP TTSNNSPGFV ALNFDVIKTH KNVTGPQGEI NTNVNVKRQT
 60 VPVKLINEQV SYASDITVGS NKQKLTVVID TGSSDLWVPD SQVSCQAGQG QDPNFCKNEG
120 TYSPSSSSSS QNLNSPFSIE YGDGTTSQGT WYKDTIGFGG ISITKQQFAD VTSTSVDQGI
180 LGIGYKTHEA EGNYDNVPVT LKNQGIISKN AYSLYLNSRQ ATSGQIIFGG VDNAKYSGAL
240 IALPVTSDNE LRIHLNTVKV AGQSINADVD VLLDSGTTIT YLQQGVADQV ISAFNGQETY
300 DANGNLFYLV DCNLSGSVDF AFDKNAKISV PASEFTAPLY TEDGQVYDQC QLLFGTSDYN
360 ILGDNFLRSA YIVYDLDDNE ISLAQVKYTT ASNIAALT
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
201629
Butler G.,Rasmussen M.D.,Lin M.F.,Santos M.A.S.,Sakthikumar S.,Munro C.A.,Rheinbay E.,Grabherr M.,Forche A.,Reedy J.L.,Agrafioti I.,Arnaud M.B.,Bates S.,Brown A.J.P.,Brunke S.,Costanzo M.C.,Fitzpatrick D.A.,de Groot P.W.J.,Harris D.,Hoyer L.L.,Hube B.,Klis F.M.,Kodira C.,Lennard N.,Logue M.E.,Martin R.,Neiman A.M.,Nikolaou E.,Quail M.A.,Quinn J.,Santos M.C.,Schmitzberger F.F.,Sherlock G.,Shah P.,Silverstein K.A.T.,Skrzypek M.S.,Soll D.,Staggs R.,Stansfield I.,Stumpf M.P.H.,Sudbery P.E.,Srikantha T.,Zeng Q.,Berman J.,Berriman M.,Heitman J.,Gow N.A.R.,Lorenz M.C.,Birren B.W.,Kellis M.,Cuomo C.A.
Evolution of pathogenicity and sexual reproduction in eight Candida genomes.
Nature
459
657-662
2009
201630
White T.C.,Miyasaki S.H.,Agabian N.
Three distinct secreted aspartyl proteinases in Candida albicans.
J. Bacteriol.
175
6126-6133
1993