Sequence of NAT_MYCSM

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
arylamine N-acetyltransferase
O86309
Mycobacterium smegmatis
275
30174
Reaction
acetyl-CoA + an arylamine = CoA + an N-acetylarylamine
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MAMDLGGYLT RIGLDGRPRP DLGTLHAIVA AHNRSIPFEN LDPLLGIPVA DLSAEALFAK
 60 LVDRRRGGYC YEHNGLLGYV LEELGFEVER LSGRVVWMRA DDAPLPAQTH NVLSVAVPGA
120 DGRYLVDVGF GGQTLTSPIR LEAGPVQQTR HEPYRLTRHG DDHTLAAQVR GEWQPLYTFT
180 TEPRPRIDLE VGSWYVSTHP GSHFVTGLTV AVVTDDARYN LRGRNLAVHR SGATEHIRFD
240 SAAQVLDAIV NRFGIDLGDL AGRDVQARVA EVLDT
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
315359
Payton M.A.,Auty R.,Delgoda R.T.,Everitt M.,Sim E.
Cloning and characterization of arylamine N-acetyltransferase genes from Mycobacterium smegmatis and Mycobacterium tuberculosis: increased expression results in isoniazid resistance.
J. Bacteriol.
181
1343-1347
1999
315360
Sandy J.,Mushtaq A.,Kawamura A.,Sinclair J.,Sim E.,Noble M.E.M.
The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis -- an enzyme which inactivates the anti-tubercular drug, isoniazid.
J. Mol. Biol.
318
1071-1083
2002
315361
Sandy J.,Mushtaq A.,Holton S.J.,Schartau P.,Noble M.E.M.,Sim E.
Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines.
Biochem. J.
390
115-123
2005