Sequence of ATPA_BOVIN
EC Number:3.6.1.14
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
adenosine 5'-tetraphosphate + H2O = ATP + phosphate
General information:
Sequence
0 MLSVRVAAAV ARALPRRAGL VSKNALGSSF IAARNLHASN SRLQKTGTAE VSSILEERIL
60 GADTSVDLEE TGRVLSIGDG IARVHGLRNV QAEEMVEFSS GLKGMSLNLE PDNVGVVVFG
120 NDKLIKEGDI VKRTGAIVDV PVGEELLGRV VDALGNAIDG KGPIGSKARR RVGLKAPGII
180 PRISVREPMQ TGIKAVDSLV PIGRGQRELI IGDRQTGKTS IAIDTIINQK RFNDGTDEKK
240 KLYCIYVAIG QKRSTVAQLV KRLTDADAMK YTIVVSATAS DAAPLQYLAP YSGCSMGEYF
300 RDNGKHALII YDDLSKQAVA YRQMSLLLRR PPGREAYPGD VFYLHSRLLE RAAKMNDAFG
360 GGSLTALPVI ETQAGDVSAY IPTNVISITD GQIFLETELF YKGIRPAINV GLSVSRVGSA
420 AQTRAMKQVA GTMKLELAQY REVAAFAQFG SDLDAATQQL LSRGVRLTEL LKQGQYSPMA
480 IEEQVAVIYA GVRGYLDKLE PSKITKFENA FLSHVISQHQ ALLSKIRTDG KISEESDAKL
540 KEIVTNFLAG FEA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
449773
Walker J.E.,Powell S.J.,Vinas O.,Runswick M.J.
ATP synthase from bovine mitochondria: complementary DNA sequence of the import precursor of a heart isoform of the alpha subunit.
Biochemistry
28
4702-4708
1989
449774
Pierce D.J.,Jordan E.M.,Breen G.A.M.
Structural organization of a nuclear gene for the alpha-subunit of the bovine mitochondrial ATP synthase complex.
Biochim. Biophys. Acta
1132
265-275
1992
449776
Breen G.A.M.
Bovine liver cDNA clones encoding a precursor of the alpha-subunit of the mitochondrial ATP synthase complex.
Biochem. Biophys. Res. Commun.
152
264-269
1988
449777
Walker J.E.,Fearnley I.M.,Gay N.J.,Gibson B.W.,Northrop F.D.,Powell S.J.,Runswick M.J.,Saraste M.,Tybulewicz V.L.J.
Primary structure and subunit stoichiometry of F1-ATPase from bovine mitochondria.
J. Mol. Biol.
184
677-701
1985
449778
Sikerwar S.S.,Malhotra S.K.
Visualization of mitochondrial coupling factor F1(ATPase) by freeze-drying.
Cell Biophys.
1
55-63
1979
449779
Rubinstein J.L.,Walker J.E.,Henderson R.
Structure of the mitochondrial ATP synthase by electron cryomicroscopy.
EMBO J.
22
6182-6192
2003
449780
Chen R.,Runswick M.J.,Carroll J.,Fearnley I.M.,Walker J.E.
Association of two proteolipids of unknown function with ATP synthase from bovine heart mitochondria.
FEBS Lett.
581
3145-3148
2007
449781
Runswick M.J.,Bason J.V.,Montgomery M.G.,Robinson G.C.,Fearnley I.M.,Walker J.E.
The affinity purification and characterization of ATP synthase complexes from mitochondria.
Open Biol.
3
120160-120160
2013
449782
Lee J.,Ding S.,Walpole T.B.,Holding A.N.,Montgomery M.G.,Fearnley I.M.,Walker J.E.
Organization of Subunits in the Membrane Domain of the Bovine F-ATPase Revealed by Covalent Cross-linking.
J. Biol. Chem.
290
13308-13320
2015
449783
Abrahams J.P.,Leslie A.G.W.,Lutter R.,Walker J.E.
Structure at 2.8-A resolution of F1-ATPase from bovine heart mitochondria.
Nature
370
621-628
1994
449784
Abrahams J.P.,Buchanan S.K.,van Raaij M.J.,Fearnley I.M.,Leslie A.G.,Walker J.E.
The structure of bovine F1-ATPase complexed with the peptide antibiotic efrapeptin.
Proc. Natl. Acad. Sci. U.S.A.
93
9420-9424
1996
449785
Orriss G.L.,Leslie A.G.,Braig K.,Walker J.E.
Bovine F1-ATPase covalently inhibited with 4-chloro-7-nitrobenzofurazan: the structure provides further support for a rotary catalytic mechanism.
Structure
6
831-837
1998
449786
Cabezon E.,Montgomery M.G.,Leslie A.G.,Walker J.E.
The structure of bovine F1-ATPase in complex with its regulatory protein IF1.
Nat. Struct. Biol.
10
744-750
2003
449787
Gledhill J.R.,Montgomery M.G.,Leslie A.G.,Walker J.E.
How the regulatory protein, IF(1), inhibits F(1)-ATPase from bovine mitochondria.
Proc. Natl. Acad. Sci. U.S.A.
104
15671-15676
2007
