Sequence of B3GN5_HUMAN
EC Number:2.4.1.206
EC Number
Recommended Name
Accession Code
Organism
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Molecular Weight [Da]
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UDP-N-acetyl-alpha-D-glucosamine + beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
General information:
Sequence
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>Q9BYG0|lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase|EC 2.4.1.206|Homo sapiens|Swiss-Prot
MRMLVSGRRVKKWQLIIQLFATCFLASLMFFWEPIDNHIVSHMKSYSYRYLINSYDFVND
TLSLKHTSAGPRYQYLINHKEKCQAQDVLLLLFVKTAPENYDRRSGIRRTWGNENYVRSQ
LNANIKTLFALGTPNPLEGEELQRKLAWEDQRYNDIIQQDFVDSFYNLTLKLLMQFSWAN
TYCPHAKFLMTADDDIFIHMPNLIEYLQSLEQIGVQDFWIGRVHRGAPPIRDKSSKYYVS
YEMYQWPAYPDYTAGAAYVISGDVAAKVYEASQTLNSSLYIDDVFMGLCANKIGIVPQDH
VFFSGEGKTPYHPCIYEKMMTSHGHLEDLQDLWKNATDPKVKTISKGFFGQIYCRLMKII
LLCKISYVDTYPCRAAFI
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1170309
Togayachi A.,Akashima T.,Ookubo R.,Kudo T.,Nishihara S.,Iwasaki H.,Natsume A.,Mio H.,Inokuchi J.,Irimura T.,Sasaki K.,Narimatsu H.
Molecular cloning and characterization of UDP-GlcNAc:lactosylceramide beta 1,3-N-acetylglucosaminyltransferase (beta 3Gn-T5), an essential enzyme for the expression of HNK-1 and Lewis X epitopes on glycolipids.
J. Biol. Chem.
276
22032-22040
2001
1170310
Henion T.R.,Zhou D.,Wolfer D.P.,Jungalwala F.B.,Hennet T.
Cloning of a mouse beta 1,3 N-acetylglucosaminyltransferase GlcNAc(beta 1,3)Gal(beta 1,4)Glc-ceramide synthase gene encoding the key regulator of lacto-series glycolipid biosynthesis.
J. Biol. Chem.
276
30261-30269
2001
1170314
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
