Sequence of CMAS2_MYCTU
EC Number:2.1.1.79
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
cyclopropane-fatty-acyl-phospholipid synthase
P9WPB5
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
302
34660
Reaction
S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid
Other sequences found for EC No. 2.1.1.79
General information:
Sequence
0 MTSQGDTTSG TQLKPPVEAV RSHYDKSNEF FKLWLDPSMT YSCAYFERPD MTLEEAQYAK
60 RKLALDKLNL EPGMTLLDIG CGWGSTMRHA VAEYDVNVIG LTLSENQYAH DKAMFDEVDS
120 PRRKEVRIQG WEEFDEPVDR IVSLGAFEHF ADGAGDAGFE RYDTFFKKFY NLTPDDGRML
180 LHTITIPDKE EAQELGLTSP MSLLRFIKFI LTEIFPGGRL PRISQVDYYS SNAGWKVERY
240 HRIGANYVPT LNAWADALQA HKDEAIALKG QETYDIYMHY LRGCSDLFRD KYTDVCQFTL
300 VK
Download this sequence
Download all sequences for 2.1.1.79
Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1170389
George K.M.,Yuan Y.,Sherman D.R.,Barry C.E. III
The biosynthesis of cyclopropanated mycolic acids in Mycobacterium tuberculosis. Identification and functional analysis of CMAS-2.
J. Biol. Chem.
270
27292-27298
1995
1170390
Shi J.,Meng S.,Wan L.,Zhang Z.,Jiang S.,Zhu H.,Dai E.,Chang L.,Gao H.,Wan K.,Zhang L.,Zhao X.,Liu H.,Lyu Z.,Zhang Y.,Xu P.
Deep N-terminomics of Mycobacterium tuberculosis H37Rv extensively correct annotated encoding genes.
Genomics
114
292-304
2022
1170391
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
1170392
Glickman M.S.,Cahill S.M.,Jacobs W.R. Jr.
The Mycobacterium tuberculosis cmaA2 gene encodes a mycolic acid trans-cyclopropane synthetase.
J. Biol. Chem.
276
2228-2233
2001
1170393
Rao V.,Gao F.,Chen B.,Jacobs W.R. Jr.,Glickman M.S.
Trans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis -induced inflammation and virulence.
J. Clin. Invest.
116
1660-1667
2006
1170394
Alahari A.,Trivelli X.,Guerardel Y.,Dover L.G.,Besra G.S.,Sacchettini J.C.,Reynolds R.C.,Coxon G.D.,Kremer L.
Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria.
PLoS ONE
2
0-0
2007
1170395
Raman K.,Yeturu K.,Chandra N.
targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.
BMC Syst. Biol.
2
109-109
2008
1170396
Vaubourgeix J.,Bardou F.,Boissier F.,Julien S.,Constant P.,Ploux O.,Daffe M.,Quemard A.,Mourey L.
S-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases.
J. Biol. Chem.
284
19321-19330
2009
1170397
Barkan D.,Rao V.,Sukenick G.D.,Glickman M.S.
Redundant function of cmaA2 and mmaA2 in Mycobacterium tuberculosis cis cyclopropanation of oxygenated mycolates.
J. Bacteriol.
192
3661-3668
2010
1170398
Kelkar D.S.,Kumar D.,Kumar P.,Balakrishnan L.,Muthusamy B.,Yadav A.K.,Shrivastava P.,Marimuthu A.,Anand S.,Sundaram H.,Kingsbury R.,Harsha H.C.,Nair B.,Prasad T.S.,Chauhan D.S.,Katoch K.,Katoch V.M.,Kumar P.,Chaerkady R.,Ramachandran S.,Dash D.,Pandey A.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol. Cell. Proteomics
10
0-0
2011
1170399
Huang C.-C.,Smith C.V.,Glickman M.S.,Jacobs W.R. Jr.,Sacchettini J.C.
Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis.
J. Biol. Chem.
277
11559-11569
2002