Sequence of SIA4C_MOUSE
EC Number:2.4.3.2
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase
Q91Y74
Mus musculus
333
38058
Reaction
CMP-N-acetyl-beta-neuraminate + a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R = CMP + an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
General information:
Sequence
0 MTSKSHWKLL ALALVLVVVM VWYSISREDR YIEFFYFPIS EKKEPCFQGE AERQASKIFG
60 NRSREQPIFL QLKDYFWVKT PSTYELPFGT KGSEDLLLRV LAITSYSIPE SIKSLECRRC
120 VVVGNGHRLR NSSLGGVINK YDVVIRLNNA PVAGYEGDVG SKTTIRLFYP ESAHFDPKIE
180 NNPDTLLVLV AFKAMDFHWI ETILSDKKRV RKGFWKQPPL IWDVNPKQVR ILNPFFMEIA
240 ADKLLSLPIQ QPRKIKQKPT TGLLAITLAL HLCDLVHIAG FGYPDASNKK QTIHYYEQIT
300 LKSMAGSGHN VSQEAIAIKR MLEMGAVKNL TYF
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1118360
Kono M.,Ohyama Y.,Lee Y.-C.,Hamamoto T.,Kojima N.,Tsuji S.
Mouse beta-galactoside alpha2,3-sialyltransferases: comparison of in vitro substrate specificities and tissue specific expression.
Glycobiology
7
469-479
1997
1118361
Okaba A.,Tawara Y.,Masa T.,Oka T.,Machida A.,Tanaka T.,Matsuhashi H.,Shiosaka S.,Kato K.
Differential expression of mRNAs for sialyltransferase isoenzymes induced in the hippocampus of mouse following kindled seizures.
J. Neurochem.
77
1185-1197
2001
1118362
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
1118363
Ellies L.G.,Ditto D.,Levy G.G.,Wahrenbrock M.,Ginsburg D.,Varki A.,Le D.T.,Marth J.D.
Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands.
Proc. Natl. Acad. Sci. U.S.A.
99
10042-10047
2002
1118364
Frommhold D.,Ludwig A.,Bixel M.G.,Zarbock A.,Babushkina I.,Weissinger M.,Cauwenberghs S.,Ellies L.G.,Marth J.D.,Beck-Sickinger A.G.,Sixt M.,Lange-Sperandio B.,Zernecke A.,Brandt E.,Weber C.,Vestweber D.,Ley K.,Sperandio M.
Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation.
J. Exp. Med.
205
1435-1446
2008
1118365
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
1118366
Mondal N.,Buffone A. Jr.,Stolfa G.,Antonopoulos A.,Lau J.T.,Haslam S.M.,Dell A.,Neelamegham S.
ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes.
Blood
125
687-696
2015
