Sequence of PARG1_CAEEL
EC Number:3.2.1.143
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
hydrolyses poly(ADP-D-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-D-ribose
General information:
Sequence
0 MSKKFIELGD PVTQDEKDYE DYVGVGFAHQ VPTMKRRKLT EHGNTTESKE DPEEPKSRDV
60 FVSSQSSDES QEDSAENPEI AKEVSENCEN LTETLKISNI ESLDNVTERS EHTLDNHKST
120 EPMEEDVNNK SNIDVAINSD EDDELVLEEN NKEMRDGEQV QQDLFADDQE LIEYPGIMKD
180 TTTQLDITDS EVETAQKMEM IEETEADSTF VGEDSKNQRQ SGTTSDEVDA DSQINLATKT
240 VRTSSSSFLS TVSTCEAPAK GRARMYQKEL EKHVIAFTEG NLTLQPDLNK VDPDRNYRYC
300 TIPNFPASQG KLREDNRYGP KIVLPQRWRE FDSRGRRRDS YFYFKRKLDG YLKCYKTTGY
360 FMFVGLLHNM WEFDPDITYK LPALEMYYKE MSELVGREEV LEKFARVARI AKTAEDILPE
420 RIYRLVGDVE SATLSHKQCA ALVARMFFAR PDSPFSFCRI LSSDKSICVE KLKFLFTYFD
480 KMSMDPPDGA VSFRLTKMDK DTFNEEWKDK KLRSLPEVEF FDEMLIEDTA LCTQVDFANE
540 HLGGGVLNHG SVQEEIRFLM CPEMMVGMLL CEKMKQLEAI SIVGAYVFSS YTGYGHTLKW
600 AELQPNHSRQ NTNEFRDRFG RLRVETIAID AILFKGSKLD CQTEQLNKAN IIREMKKASI
660 GFMSQGPKFT NIPIVTGWWG CGAFNGDKPL KFIIQVIAAG VADRPLHFCS FGEPELAAKC
720 KKIIERMKQK DVTLGMLFSM INNTGLPHKH FEFYVFDRIS TYLSSSEDVE SSKSSPSVSR
780 A
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1019384
St-Laurent J.F.,Gagnon S.N.,Dequen F.,Hardy I.,Desnoyers S.
Altered DNA damage response in Caenorhabditis elegans with impaired poly(ADP-ribose) glycohydrolases genes expression.
DNA Repair
6
329-343
2007
1019385
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science
282
2012-2018
1998
