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Sequence of RBP1_HUMAN

EC Number:7.6.2.2

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ABC-type xenobiotic transporter
Q15311
Homo sapiens
655
76063
Reaction
ATP + H2O + xenobiotic[side 1] = ADP + phosphate + xenobiotic[side 2]
Other sequences found for EC No. 7.6.2.2

General information:

Sequence
show sequence in fasta format
  0 MTECFLPPTS SPSEHRRVEH GSGLTRTPSS EEISPTKFPG LYRTGEPSPP HDILHEPPDV
 60 VSDDEKDHGK KKGKFKKKEK RTEGYAAFQE DSSGDEAESP SKMKRSKGIH VFKKPSFSKK
120 KEKDFKIKEK PKEEKHKEEK HKEEKHKEKK SKDLTAADVV KQWKEKKKKK KPIQEPEVPQ
180 IDVPNLKPIF GIPLADAVER TMMYDGIRLP AVFRECIDYV EKYGMKCEGI YRVSGIKSKV
240 DELKAAYDRE ESTNLEDYEP NTVASLLKQY LRDLPENLLT KELMPRFEEA CGRTTETEKV
300 QEFQRLLKEL PECNYLLISW LIVHMDHVIA KELETKMNIQ NISIVLSPTV QISNRVLYVF
360 FTHVQELFGN VVLKQVMKPL RWSNMATMPT LPETQAGIKE EIRRQEFLLN CLHRDLQGGI
420 KDLSKEERLW EVQRILTALK RKLREAKRQE CETKIAQEIA SLSKEDVSKE EMNENEEVIN
480 ILLAQENEIL TEQEELLAME QFLRRQIASE KEEIERLRAE IAEIQSRQQH GRSETEEYSS
540 ESESESEDEE ELQIILEDLQ RQNEELEIKN NHLNQAIHEE REAIIELRVQ LRLLQMQRAK
600 AEQQAQEDEE PEWRGGAVQP PRDGVLEPKA AKEQPKAGKE PAKPSPSRDR KETSI
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
83596
Jullien-Flores V.,Dorseuil O.,Romero F.,Letourneur F.,Saragosti S.,Berger R.,Tavitian A.,Gacon G.,Camonis J.H.
Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity.
J. Biol. Chem.
270
22473-22477
1995
83597
Awasthi S.,Cheng J.,Singhal S.S.,Saini M.K.,Pandya U.,Pikula S.,Bandorowicz-Pikula J.,Singh S.V.,Zimniak P.,Awasthi Y.C.
Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin.
Biochemistry
39
9327-9334
2000
83599
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
83600
Awasthi S.,Singhal S.S.,Pikula S.,Piper J.T.,Srivastava S.K.,Torman R.T.,Bandorowicz-Pikula J.,Lin J.T.,Singh S.V.,Zimniak P.,Awasthi Y.C.
ATP-Dependent human erythrocyte glutathione-conjugate transporter. II. Functional reconstitution of transport activity.
Biochemistry
37
5239-5248
1998
83601
Ikeda M.,Ishida O.,Hinoi T.,Kishida S.,Kikuchi A.
Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral.
J. Biol. Chem.
273
814-821
1998
83602
Jullien-Flores V.,Mahe Y.,Mirey G.,Leprince C.,Meunier-Bisceuil B.,Sorkin A.,Camonis J.H.
RLIP76, an effector of the GTPase Ral, interacts with the AP2 complex: involvement of the Ral pathway in receptor endocytosis.
J. Cell Sci.
113
2837-2844
2000
83603
Awasthi S.,Cheng J.Z.,Singhal S.S.,Pandya U.,Sharma R.,Singh S.V.,Zimniak P.,Awasthi Y.C.
Functional reassembly of ATP-dependent xenobiotic transport by the N- and C-terminal domains of RLIP76 and identification of ATP binding sequences.
Biochemistry
40
4159-4168
2001
83604
Sharma R.,Singhal S.S.,Cheng J.,Yang Y.,Sharma A.,Zimniak P.,Awasthi S.,Awasthi Y.C.
RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes.
Arch. Biochem. Biophys.
391
171-179
2001
83605
Rosse C.,L'Hoste S.,Offner N.,Picard A.,Camonis J.
RLIP, an effector of the Ral GTPases, is a platform for Cdk1 to phosphorylate epsin during the switch off of endocytosis in mitosis.
J. Biol. Chem.
278
30597-30604
2003
83606
Yadav S.,Singhal S.S.,Singhal J.,Wickramarachchi D.,Knutson E.,Albrecht T.B.,Awasthi Y.C.,Awasthi S.
Identification of membrane-anchoring domains of RLIP76 using deletion mutant analyses.
Biochemistry
43
16243-16253
2004
83607
Olsen J.V.,Blagoev B.,Gnad F.,Macek B.,Kumar C.,Mortensen P.,Mann M.
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Cell
127
635-648
2006
83608
Cantin G.T.,Yi W.,Lu B.,Park S.K.,Xu T.,Lee J.-D.,Yates J.R. III
Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
J. Proteome Res.
7
1346-1351
2008
83609
Zahedi R.P.,Lewandrowski U.,Wiesner J.,Wortelkamp S.,Moebius J.,Schuetz C.,Walter U.,Gambaryan S.,Sickmann A.
Phosphoproteome of resting human platelets.
J. Proteome Res.
7
526-534
2008
83610
Dephoure N.,Zhou C.,Villen J.,Beausoleil S.A.,Bakalarski C.E.,Elledge S.J.,Gygi S.P.
A quantitative atlas of mitotic phosphorylation.
Proc. Natl. Acad. Sci. U.S.A.
105
10762-10767
2008
83611
Gauci S.,Helbig A.O.,Slijper M.,Krijgsveld J.,Heck A.J.,Mohammed S.
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Anal. Chem.
81
4493-4501
2009
83612
Oppermann F.S.,Gnad F.,Olsen J.V.,Hornberger R.,Greff Z.,Keri G.,Mann M.,Daub H.
Large-scale proteomics analysis of the human kinome.
Mol. Cell. Proteomics
8
1751-1764
2009
83613
Mayya V.,Lundgren D.H.,Hwang S.-I.,Rezaul K.,Wu L.,Eng J.K.,Rodionov V.,Han D.K.
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
Sci. Signal.
2
0-0
2009
83614
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
83615
Kashatus D.F.,Lim K.H.,Brady D.C.,Pershing N.L.,Cox A.D.,Counter C.M.
RALA and RALBP1 regulate mitochondrial fission at mitosis.
Nat. Cell Biol.
13
1108-1115
2011
83616
Rigbolt K.T.,Prokhorova T.A.,Akimov V.,Henningsen J.,Johansen P.T.,Kratchmarova I.,Kassem M.,Mann M.,Olsen J.V.,Blagoev B.
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
Sci. Signal.
4
0-0
2011
83617
Fillatre J.,Delacour D.,Van Hove L.,Bagarre T.,Houssin N.,Soulika M.,Veitia R.A.,Moreau J.
Dynamics of the subcellular localization of RalBP1/RLIP through the cell cycle: the role of targeting signals and of protein-protein interactions.
FASEB J.
26
2164-2174
2012
83618
Zhou H.,Di Palma S.,Preisinger C.,Peng M.,Polat A.N.,Heck A.J.,Mohammed S.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
J. Proteome Res.
12
260-271
2013
83619
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
83620
Fenwick R.B.,Campbell L.J.,Rajasekar K.,Prasannan S.,Nietlispach D.,Camonis J.,Owen D.,Mott H.R.
The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction.
Structure
18
985-995
2010
83621
Rajasekar K.V.,Campbell L.J.,Nietlispach D.,Owen D.,Mott H.R.
The structure of the RLIP76 RhoGAP-Ral binding domain dyad: fixed position of the domains leads to dual engagement of small G proteins at the membrane.
Structure
21
2131-2142
2013