Sequence of MTNN_ECOLI

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
aminodeoxyfutalosine nucleosidase
P0AF12
Escherichia coli (strain K12)
232
24354
Reaction
6-amino-6-deoxyfutalosine + H2O = dehypoxanthine futalosine + adenine
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MKIGIIGAME EEVTLLRDKI ENRQTISLGG CEIYTGQLNG TEVALLKSGI GKVAAALGAT
 60 LLLEHCKPDV IINTGSAGGL APTLKVGDIV VSDEARYHDA DVTAFGYEYG QLPGCPAGFK
120 ADDKLIAAAE ACIAELNLNA VRGLIVSGDA FINGSVGLAK IRHNFPQAIA VEMEATAIAH
180 VCHNFNVPFV VVRAISDVAD QQSHLSFDEF LAVAAKQSSL MVESLVQKLA HG
Download this sequence
in fasta format
Download all sequences for 3.2.2.30
in fasta format
in csv (Excel, OpenOffice) format
Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
440451
Wurgler S.M.,Richardson C.C.
Structure and regulation of the gene for dGTP triphosphohydrolase from Escherichia coli.
Proc. Natl. Acad. Sci. U.S.A.
87
2740-2744
1990
440452
Cornell K.A.,Riscoe M.K.
Cloning and expression of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase: identification of the pfs gene product.
Biochim. Biophys. Acta
1396
8-14
1998
440453
Fujita N.,Mori H.,Yura T.,Ishihama A.
Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region.
Nucleic Acids Res.
22
1637-1639
1994
440455
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
440456
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
440457
Della Ragione F.,Porcelli M.,Carteni-Farina M.,Zappia V.,Pegg A.E.
Escherichia coli S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase. Purification, substrate specificity and mechanism of action.
Biochem. J.
232
335-341
1985
440458
Cornell K.A.,Swarts W.E.,Barry R.D.,Riscoe M.K.
Characterization of recombinant Eschericha coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase: analysis of enzymatic activity and substrate specificity.
Biochem. Biophys. Res. Commun.
228
724-732
1996
440459
VanBogelen R.A.,Abshire K.Z.,Moldover B.,Olson E.R.,Neidhardt F.C.
Escherichia coli proteome analysis using the gene-protein database.
Electrophoresis
18
1243-1251
1997
440460
Lee J.E.,Luong W.,Huang D.J.,Cornell K.A.,Riscoe M.K.,Howell P.L.
Mutational analysis of a nucleosidase involved in quorum-sensing autoinducer-2 biosynthesis.
Biochemistry
44
11049-11057
2005
440461
Lee J.E.,Cornell K.A.,Riscoe M.K.,Howell P.L.
Structure of E. coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases.
Structure
9
941-953
2001
440462
Lee J.E.,Cornell K.A.,Riscoe M.K.,Howell P.L.
Structure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysis.
J. Biol. Chem.
278
8761-8770
2003
440463
Singh V.,Evans G.B.,Lenz D.H.,Mason J.M.,Clinch K.,Mee S.,Painter G.F.,Tyler P.C.,Furneaux R.H.,Lee J.E.,Howell P.L.,Schramm V.L.
Femtomolar transition state analogue inhibitors of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli.
J. Biol. Chem.
280
18265-18273
2005
440464
Lee J.E.,Smith G.D.,Horvatin C.,Huang D.J.,Cornell K.A.,Riscoe M.K.,Howell P.L.
Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis.
J. Mol. Biol.
352
559-574
2005