Sequence of GSHR_PLAFK
EC Number:1.8.1.7
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glutathione-disulfide reductase
Q94655
Plasmodium falciparum (isolate K1 / Thailand)
500
56561
Reaction
2 glutathione + NADP+ = glutathione disulfide + NADPH + H+
Other sequences found for EC No. 1.8.1.7
General information:
Sequence
0 MVYDLIVIGG GSGGMAAARR AARHNAKVAL VEKSRLGGTC VNVGCVPKKI MFNAASVHDI
60 LENSRHYGFD TKFSFNLPLL VERRDKYIQR LNNIYRQNLS KDKVDLYEGT ASFLSENRIL
120 IKGTKDNNNK DNGPLNEEIL EGRNILIAVG NKPVFPPVKG IENTISSDEF FNIKESKKIG
180 IVGSGYIAVE LINVIKRLGI DSYIFARGNR ILRKFDESVI NVLENDMKKN NINIVTFADV
240 VEIKKVSDKN LSIHLSDGRI YEHFDHVIYC VGRSPDTENL KLEKLNVETN NNYIVVDENQ
300 RTSVNNIYAV GDCCMVKKSK EIEDLNLLKL YNEERYLNKK ENVTEDIFYN VQLTPVAINA
360 GRLLADRLFL KKTRKTNYKL IPTVIFSHPP IGTIGLSEEA AIQIYGKENV KIYESKFTNL
420 FFSVYDIEPE LKEKTYLKLV CVGKDELIKG LHIIGLNADE IVQGFAVALK MNATKKDFDE
480 TIPIHPTAAE EFLTLQPWMK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
935024
Faerber P.M.,Becker K.,Mueller S.
Molecular cloning and characterization of a putative glutathione reductase gene, the PfGR2 gene, from Plasmodium falciparum.
Eur. J. Biochem.
239
655-661
1996
935025
Krauth-Siegel R.L.,Muller J.G.,Lottspeich F.,Schirmer R.H.
Glutathione reductase and glutamate dehydrogenase of Plasmodium falciparum, the causative agent of tropical malaria.
Eur. J. Biochem.
235
345-350
1996
935026
Sarma G.N.,Savvides S.N.,Becker K.,Schirmer M.,Schirmer R.H.,Karplus P.A.
Glutathione reductase of the malarial parasite Plasmodium falciparum: crystal structure and inhibitor development.
J. Mol. Biol.
328
893-907
2003
