Sequence of NEOG_STRFR
EC Number:1.1.3.44
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
6'''-deamino-6'''-hydroxyneomycin C + O2 = 6'''-deamino-6'''-oxoneomycin C + H2O2
Other sequences found for EC No. 1.1.3.44
General information:
Sequence
0 MKRLRGTLPS DARHAWHPEP LGPAHRDGWD TRDDDRVWDV VVIGSGASGS VAADRLVRQG
60 LDVLMIEEGF RLSPDLGNPE LDDMCRTALA RDGQGGWTDE GWPWTTSNLG GGTVFYGGAS
120 WRYRPFDFDP SELVDAGGLD VRWPYGLAEL APYYDVLERR LGVCGGEEGE GSRGPAHPPT
180 AAAEVLYEAG TALGYEPFPT PLAINRHAHG GRSACERNSL CVSHQCSTGA KGDAVAVFLA
240 PLAAHPNFTL RTGVRALRLN QDRPDAVGSV TCLDRLGRTT HRVRARSFVV ACNAIQSAAL
300 LLRSRGGRAP DGVGNHSGLV GRGLTMKLSE YVSGVVDAPS AATLADWRAH AGPFSTIAFL
360 DHYLDADCPT GVGGMIYESK NDMPSRIRDD VLELRIETIL ADHPNLDNRV RLSSHADEDG
420 VPAVVIDYTP DPRDLRRLAY MTDVCERLLR KAGATGIAHE ESGFAQGSCH LHGTCRAGDD
480 PATSVVDGWG RVHSAPNVYV VDGGFMPYPG GLNPTLTIQA HALRSAKAVA GDLVSRHTAH
540 V
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
831114
Kudo F.,Yamamoto Y.,Yokoyama K.,Eguchi T.,Kakinuma K.
Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773.
J. Antibiot.
58
766-774
2005
831115
Huang F.,Haydock S.F.,Mironenko T.,Spiteller D.,Li Y.,Spencer J.B.
The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine.
Org. Biomol. Chem.
3
1410-1418
2005
831118
Huang F.,Spiteller D.,Koorbanally N.A.,Li Y.,Llewellyn N.M.,Spencer J.B.
Elaboration of neosamine rings in the biosynthesis of neomycin and butirosin.
ChemBioChem
8
283-288
2007
831119
Clausnitzer D.,Piepersberg W.,Wehmeier U.F.
The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin.
J. Appl. Microbiol.
111
642-651
2011
