Sequence of C71DC_CATRO

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
tabersonine 16-hydroxylase
P98183
Catharanthus roseus
506
58079
Reaction
tabersonine + [reduced NADPH-hemoprotein reductase] + O2 = 16-hydroxytabersonine + [oxidized NADPH-hemoprotein reductase] + H2O
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MEFYYFLYLA FLLFCFILSK TTKKFGQNSQ YSNHDELPPG PPQIPILGNA HQLSGGHTHH
 60 ILRDLAKKYG PLMHLKIGEV STIVASSPQI AEEIFRTHDI LFADRPSNLE SFKIVSYDFS
120 DMVVSPYGNY WRQLRKISMM ELLSQKSVQS FRSIREEEVL NFIKSIGSKE GTRINLSKEI
180 SLLIYGITTR AAFGEKNKNT EEFIRLLDQL TKAVAEPNIA DMFPSLKFLQ LISTSKYKIE
240 KIHKQFDVIV ETILKGHKEK INKPLSQENG EKKEDLVDVL LNIQRRNDFE APLGDKNIKA
300 IIFNIFSAGT ETSSTTVDWA MCEMIKNPTV MKKAQEEVRK VFNEEGNVDE TKLHQLKYLQ
360 AVIKETLRLH PPVPLLLPRE CREQCKIKGY TIPSKSRVIV NAWAIGRDPN YWIEPEKFNP
420 DRFLESKVDF KGNSFEYLPF GGGRRICPGI TFALANIELP LAQLLFHFDW QSNTEKLNMK
480 ESRGVTVRRE DDLYLTPVNF SSSSPA
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
754478
Guirimand G.,Guihur A.,Poutrain P.,Hericourt F.,Mahroug S.,St-Pierre B.,Burlat V.,Courdavault V.
Spatial organization of the vindoline biosynthetic pathway in Catharanthus roseus.
J. Plant Physiol.
168
549-557
2011
754479
Schroeder G.,Unterbusch E.,Kaltenbach M.,Schmidt J.,Strack D.,Schroeder J.
Light-induced cytochrome P450-dependent enzyme in indole alkaloid biosynthesis: tabersonine 16-hydroxylase.
FEBS Lett.
458
97-102
1999
754480
St Pierre B.,De Luca V.
A cytochrome P-450 monooxygenase catalyzes the first step in the conversion of tabersonine to vindoline in Catharanthus roseus.
Plant Physiol.
109
131-139
1995
754481
Murata J.,De Luca V.
Localization of tabersonine 16-hydroxylase and 16-OH tabersonine-16-O-methyltransferase to leaf epidermal cells defines them as a major site of precursor biosynthesis in the vindoline pathway in Catharanthus roseus.
Plant J.
44
581-594
2005
754482
Besseau S.,Kellner F.,Lanoue A.,Thamm A.M.,Salim V.,Schneider B.,Geu-Flores F.,Hoefer R.,Guirimand G.,Guihur A.,Oudin A.,Glevarec G.,Foureau E.,Papon N.,Clastre M.,Giglioli-Guivarc'h N.,St-Pierre B.,Werck-Reichhart D.,Burlat V.,De Luca V.,O'Connor S.E.,Courdavault V.
A pair of tabersonine 16-hydroxylases initiates the synthesis of vindoline in an organ-dependent manner in Catharanthus roseus.
Plant Physiol.
163
1792-1803
2013