Sequence of TYRO3_HUMAN
EC Number:2.7.10.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Other sequences found for EC No. 2.7.10.1
General information:
Sequence
0 MALRRSMGRP GLPPLPLPPP PRLGLLLAAL ASLLLPESAA AGLKLMGAPV KLTVSQGQPV
60 KLNCSVEGME EPDIQWVKDG AVVQNLDQLY IPVSEQHWIG FLSLKSVERS DAGRYWCQVE
120 DGGETEISQP VWLTVEGVPF FTVEPKDLAV PPNAPFQLSC EAVGPPEPVT IVWWRGTTKI
180 GGPAPSPSVL NVTGVTQSTM FSCEAHNLKG LASSRTATVH LQALPAAPFN ITVTKLSSSN
240 ASVAWMPGAD GRALLQSCTV QVTQAPGGWE VLAVVVPVPP FTCLLRDLVP ATNYSLRVRC
300 ANALGPSPYA DWVPFQTKGL APASAPQNLH AIRTDSGLIL EWEEVIPEAP LEGPLGPYKL
360 SWVQDNGTQD ELTVEGTRAN LTGWDPQKDL IVRVCVSNAV GCGPWSQPLV VSSHDRAGQQ
420 GPPHSRTSWV PVVLGVLTAL VTAAALALIL LRKRRKETRF GQAFDSVMAR GEPAVHFRAA
480 RSFNRERPER IEATLDSLGI SDELKEKLED VLIPEQQFTL GRMLGKGEFG SVREAQLKQE
540 DGSFVKVAVK MLKADIIASS DIEEFLREAA CMKEFDHPHV AKLVGVSLRS RAKGRLPIPM
600 VILPFMKHGD LHAFLLASRI GENPFNLPLQ TLIRFMVDIA CGMEYLSSRN FIHRDLAARN
660 CMLAEDMTVC VADFGLSRKI YSGDYYRQGC ASKLPVKWLA LESLADNLYT VQSDVWAFGV
720 TMWEIMTRGQ TPYAGIENAE IYNYLIGGNR LKQPPECMED VYDLMYQCWS ADPKQRPSFT
780 CLRMELENIL GQLSVLSASQ DPLYINIERA EEPTAGGSLE LPGRDQPYSG AGDGSGMGAV
840 GGTPSDCRYI LTPGGLAEQP GQAEHQPESP LNETQRLLLL QQGLLPHSSC
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
750643
Mark M.R.,Scadden D.T.,Wang Z.,Gu Q.,Goddard A.,Godowski P.J.
RSE, a novel receptor-type tyrosine kinase with homology to Axl/Ufo, is expressed at high levels in the brain.
J. Biol. Chem.
269
10720-10728
1994
750644
Ohashi K.,Mizuno K.,Kuma K.,Miyata T.,Nakamura T.
Cloning of the cDNA for a novel receptor tyrosine kinase, Sky, predominantly expressed in brain.
Oncogene
9
699-705
1994
750645
Crosier K.E.,Hall L.R.,Lewis P.M.,Morris C.M.,Wood C.R.,Morris J.C.,Crosier P.S.
Isolation and characterization of the human DTK receptor tyrosine kinase.
Growth Factors
11
137-144
1994
750646
Kajii Y.,Ninomiya D.,Kato M.,Mizuguchi M.,Saji M.,Katsumoto T.,Ohno K.,Takashima S.,Onodera K.
A tyrosine kinase-like molecule is localized in the nuclear membrane of neurons: hippocampal behavior under stress.
Biol. Cell
88
45-54
1996
750647
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
750648
Polvi A.,Armstrong E.,Lai C.,Lemke G.,Huebner K.,Spritz R.A.,Giuda L.C.,Nicholls R.D.,Alitalo K.
The human TYRO3 gene and pseudogene are located in chromosome 15q14-q25.
Gene
134
289-293
1993
750649
Toshima J.,Ohashi K.,Iwashita S.,Mizuno K.
Autophosphorylation activity and association with Src family kinase of Sky receptor tyrosine kinase.
Biochem. Biophys. Res. Commun.
209
656-663
1995
750650
Godowski P.J.,Mark M.R.,Chen J.,Sadick M.D.,Raab H.,Hammonds R.G.
Reevaluation of the roles of protein S and Gas6 as ligands for the receptor tyrosine kinase Rse/Tyro 3.
Cell
82
355-358
1995
750651
Hafizi S.,Dahlback B.
Signalling and functional diversity within the Axl subfamily of receptor tyrosine kinases.
Cytokine Growth Factor Rev.
17
295-304
2006
750652
Shimojima M.,Takada A.,Ebihara H.,Neumann G.,Fujioka K.,Irimura T.,Jones S.,Feldmann H.,Kawaoka Y.
Tyro3 family-mediated cell entry of Ebola and Marburg viruses.
J. Virol.
80
10109-10116
2006
750653
Lemke G.,Rothlin C.V.
Immunobiology of the TAM receptors.
Nat. Rev. Immunol.
8
327-336
2008
750654
Cosemans J.M.,Van Kruchten R.,Olieslagers S.,Schurgers L.J.,Verheyen F.K.,Munnix I.C.,Waltenberger J.,Angelillo-Scherrer A.,Hoylaerts M.F.,Carmeliet P.,Heemskerk J.W.
Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization.
J. Thromb. Haemost.
8
1797-1808
2010
750655
Shimojima M.,Stroher U.,Ebihara H.,Feldmann H.,Kawaoka Y.
Identification of cell surface molecules involved in dystroglycan-independent Lassa virus cell entry.
J. Virol.
86
2067-2078
2012
750656
Shimojima M.,Kawaoka Y.
Cell surface molecules involved in infection mediated by lymphocytic choriomeningitis virus glycoprotein.
J. Vet. Med. Sci.
74
1363-1366
2012
750657
Zhou H.,Di Palma S.,Preisinger C.,Peng M.,Polat A.N.,Heck A.J.,Mohammed S.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
J. Proteome Res.
12
260-271
2013
750658
Moller-Tank S.,Maury W.
Phosphatidylserine receptors: enhancers of enveloped virus entry and infection.
Virology
468
565-580
2014
750659
Heiring C.,Dahlbaeck B.,Muller Y.A.
Ligand recognition and homophilic interactions in Tyro3: structural insights into the Axl/Tyro3 receptor tyrosine kinase family.
J. Biol. Chem.
279
6952-6958
2004
750660
Greenman C.,Stephens P.,Smith R.,Dalgliesh G.L.,Hunter C.,Bignell G.,Davies H.,Teague J.,Butler A.,Stevens C.,Edkins S.,O'Meara S.,Vastrik I.,Schmidt E.E.,Avis T.,Barthorpe S.,Bhamra G.,Buck G.,Choudhury B.,Clements J.,Cole J.,Dicks E.,Forbes S.,Gray K.,Halliday K.,Harrison R.,Hills K.,Hinton J.,Jenkinson A.,Jones D.,Menzies A.,Mironenko T.,Perry J.,Raine K.,Richardson D.,Shepherd R.,Small A.,Tofts C.,Varian J.,Webb T.,West S.,Widaa S.,Yates A.,Cahill D.P.,Louis D.N.,Goldstraw P.,Nicholson A.G.,Brasseur F.,Looijenga L.,Weber B.L.,Chiew Y.-E.,DeFazio A.,Greaves M.F.,Green A.R.,Campbell P.,Birney E.,Easton D.F.,Chenevix-Trench G.,Tan M.-H.,Khoo S.K.,Teh B.T.,Yuen S.T.,Leung S.Y.,Wooster R.,Futreal P.A.,Stratton M.R.
Patterns of somatic mutation in human cancer genomes.
Nature
446
153-158
2007
