Sequence of TAM_CHOCO
EC Number:5.4.3.6
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate
General information:
Sequence
0 MKITGSNLSI YDVADVCMKR ATVELDPSQL ERVAVAHERT QAWGEAQHPI YGVNTGFGEL
60 VPVMIPRQHK RELQENLIRS HAAGGGEPFA DDVVRAIMLA RLNCLMKGYS GASVETVKLL
120 AEFINRGIHP VIPQQGSLGA SGDLSPLSHI ALALIGEGTV SFKGQVRKTG DVLREEGLKP
180 LELGFKGGLT LINGTSAMTG AACVALGRAY HLFRLALLAT ADFVQCLGGS TGPFEERGHL
240 PKNHSGQVIV AREIRKLLAG SQLTSDHQDL MKEMVARSGV GNDVVDTGVY LQDAYTLRAV
300 PQILGPVLDT LDFARKLIEE ELNSTNDNPL IFDVPEQTFH GANFHGQYVA MACDYLNIAV
360 TEIGVLAERQ LNRLVDPNIN GKLPPFLASA HSGLLCGFEG GQYLATSIAS ENLDLAAPSS
420 IKSLPSNGSN QDVVSMGTTS ARKSLRLCEN VGTIVSTLIA ACNQAGHILG NERFSPPIRE
480 LHGELSRSVP LYQDDSPIFE LFQTVRAFVG GDGFRAHLVT HLDLAATTAS S
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
724001
Rachid S.,Krug D.,Kunze B.,Kochems I.,Scharfe M.,Zabriskie T.M.,Blocker H.,Muller R.
Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5.
Chem. Biol.
13
667-681
2006
724002
Rachid S.,Krug D.,Weissman K.J.,Muller R.
Biosynthesis of (R)-beta-tyrosine and its incorporation into the highly cytotoxic chondramides produced by Chondromyces crocatus.
J. Biol. Chem.
282
21810-21817
2007
724003
Krug D.,Muller R.
Discovery of additional members of the tyrosine aminomutase enzyme family and the mutational analysis of CmdF.
ChemBioChem
10
741-750
2009
