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Sequence of TUBAT_MYCTU

EC Number:2.5.1.153

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
adenosine tuberculosinyltransferase
P9WJ61
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
296
34031
Reaction
tuberculosinyl diphosphate + adenosine = 1-tuberculosinyladenosine + diphosphate

General information:

Sequence
show sequence in fasta format
  0 MNLVSEKEFL DLPLVSVAEI VRCRGPKVSV FPFDGTRRWF HLECNPQYDD YQQAALRQSI
 60 RILKMLFEHG IETVISPIFS DDLLDRGDRY IVQALEGMAL LANDEEILSF YKEHEVHVLF
120 YGDYKKRLPS TAQGAAVVKS FDDLTISTSS NTEHRLCFGV FGNDAAESVA QFSISWNETH
180 GKPPTRREII EGYYGEYVDK ADMFIGFGRF STFDFPLLSS GKTSLYFTVA PSYYMTETTL
240 RRILYDHIYL RHFRPKPDYS AMSADQLNVL RNRYRAQPDR VFGVGCVHDG IWFAEG
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
664371
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
664372
Nakano C.,Ootsuka T.,Takayama K.,Mitsui T.,Sato T.,Hoshino T.
Characterization of the Rv3378c gene product, a new diterpene synthase for producing tuberculosinol and (13R, S)-isotuberculosinol (nosyberkol), from the Mycobacterium tuberculosis H37Rv genome.
Biosci. Biotechnol. Biochem.
75
75-81
2011
664373
Kelkar D.S.,Kumar D.,Kumar P.,Balakrishnan L.,Muthusamy B.,Yadav A.K.,Shrivastava P.,Marimuthu A.,Anand S.,Sundaram H.,Kingsbury R.,Harsha H.C.,Nair B.,Prasad T.S.,Chauhan D.S.,Katoch K.,Katoch V.M.,Kumar P.,Chaerkady R.,Ramachandran S.,Dash D.,Pandey A.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol. Cell. Proteomics
10
M111.011627-M111.011627
2011
664374
Hoshino T.,Nakano C.,Ootsuka T.,Shinohara Y.,Hara T.
Substrate specificity of Rv3378c, an enzyme from Mycobacterium tuberculosis, and the inhibitory activity of the bicyclic diterpenoids against macrophage phagocytosis.
Org. Biomol. Chem.
9
2156-2165
2011
664375
Buter J.,Cheng T.Y.,Ghanem M.,Grootemaat A.E.,Raman S.,Feng X.,Plantijn A.R.,Ennis T.,Wang J.,Cotton R.N.,Layre E.,Ramnarine A.K.,Mayfield J.A.,Young D.C.,Jezek Martinot A.,Siddiqi N.,Wakabayashi S.,Botella H.,Calderon R.,Murray M.,Ehrt S.,Snider B.B.,Reed M.B.,Oldfield E.,Tan S.,Rubin E.J.,Behr M.A.,van der Wel N.N.,Minnaard A.J.,Moody D.B.
Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
Nat. Chem. Biol.
15
889-899
2019
664376
Chan H.C.,Feng X.,Ko T.P.,Huang C.H.,Hu Y.,Zheng Y.,Bogue S.,Nakano C.,Hoshino T.,Zhang L.,Lv P.,Liu W.,Crick D.C.,Liang P.H.,Wang A.H.,Oldfield E.,Guo R.T.
Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis.
J. Am. Chem. Soc.
136
2892-2896
2014
664377
Layre E.,Lee H.J.,Young D.C.,Martinot A.J.,Buter J.,Minnaard A.J.,Annand J.W.,Fortune S.M.,Snider B.B.,Matsunaga I.,Rubin E.J.,Alber T.,Moody D.B.
Molecular profiling of Mycobacterium tuberculosis identifies tuberculosinyl nucleoside products of the virulence-associated enzyme Rv3378c.
Proc. Natl. Acad. Sci. U.S.A.
111
2978-2983
2014