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Sequence of CATD_BOVIN

EC Number:3.4.23.5

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
cathepsin D
P80209
Bos taurus
390
42491
Reaction
Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His bond in B chain of insulin

General information:

Sequence
show sequence in normal format
>P80209|cathepsin D|EC 3.4.23.5|Bos taurus|Swiss-Prot
VIRIPLHKFTSIRRTMSEAAGXVXXLIAKGPISKYATGEPAVRQGPIPELLKNYMDAQYY
GEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWTHRKYNSDKSSTYVKNGTTFDI
HYGSGSLSGYLSQDTVSVPCNPSSSSPGGVTVQRQTFGEAIKQPGVVFIAAKFDGILGMA
YPRISVNNVLPVFDNLMQQKLVDKNVFSFFLNRDPKAQPGGELMLGGTDSKYYRGSLMFH
NVTRQAYWQIHMDQLDVGSSLTVCKGGCEAIVDTGTSLIVGPVEEVRELQKAIGAVPLIQ
GEYMIPCEKVSSLPEVTVKLGGKDYALSPEDYALKVSQAETTVCLSGFMGMDIPPPGGPL
WILGDVFIGRYYTVFDRDQNRVGLAEAARL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
640394
Larsen L.B.,Boisen A.,Petersen T.E.
Procathepsin D cannot autoactivate to cathepsin D at acid pH.
FEBS Lett.
319
54-58
1993
640395
Metcalf P.,Fusek M.
Two crystal structures for cathepsin D: the lysosomal targeting signal and active site.
EMBO J.
12
1293-1302
1993