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Sequence of PPM1B_HUMAN

EC Number:3.1.3.16

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
protein-serine/threonine phosphatase
O75688
Homo sapiens
479
52643
Reaction
[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate
Other sequences found for EC No. 3.1.3.16

General information:

Sequence
show sequence in fasta format
  0 MGAFLDKPKT EKHNAHGAGN GLRYGLSSMQ GWRVEMEDAH TAVVGIPHGL EDWSFFAVYD
 60 GHAGSRVANY CSTHLLEHIT TNEDFRAAGK SGSALELSVE NVKNGIRTGF LKIDEYMRNF
120 SDLRNGMDRS GSTAVGVMIS PKHIYFINCG DSRAVLYRNG QVCFSTQDHK PCNPREKERI
180 QNAGGSVMIQ RVNGSLAVSR ALGDYDYKCV DGKGPTEQLV SPEPEVYEIL RAEEDEFIIL
240 ACDGIWDVMS NEELCEYVKS RLEVSDDLEN VCNWVVDTCL HKGSRDNMSI VLVCFSNAPK
300 VSDEAVKKDS ELDKHLESRV EEIMEKSGEE GMPDLAHVMR ILSAENIPNL PPGGGLAGKR
360 NVIEAVYSRL NPHRESDGAS DEAEESGSQG KLVEALRQMR INHRGNYRQL LEEMLTSYRL
420 AKVEGEESPA EPAATATSSN SDAGNPVTMQ ESHTESESGL AELDSSNEDA GTKMSGEKI
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
589217
Marely A.E.,Kline A.,Crabtree G.,Sullivan J.E.,Beri R.K.
The cloning expression and tissue distribution of human PP2Cbeta.
FEBS Lett.
431
121-124
1998
589218
Cheng A.,Kaldis P.,Solomon M.J.
Dephosphorylation of human cyclin-dependent kinases by protein phosphatase type 2Calpha and beta2 isoforms.
J. Biol. Chem.
275
34744-34749
2000
589220
Parvari R.,Gonen Y.,Alshafee I.,Buriakovsky S.,Regev K.,Hershkovitz E.
The 2p21 deletion syndrome: characterization of the transcription content.
Genomics
86
195-211
2005
589221
Hu R.-M.,Han Z.-G.,Song H.-D.,Peng Y.-D.,Huang Q.-H.,Ren S.-X.,Gu Y.-J.,Huang C.-H.,Li Y.-B.,Jiang C.-L.,Fu G.,Zhang Q.-H.,Gu B.-W.,Dai M.,Mao Y.-F.,Gao G.-F.,Rong R.,Ye M.,Zhou J.,Xu S.-H.,Gu J.,Shi J.-X.,Jin W.-R.,Zhang C.-K.,Wu T.-M.,Huang G.-Y.,Chen Z.,Chen M.-D.,Chen J.-L.
Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.
Proc. Natl. Acad. Sci. U.S.A.
97
9543-9548
2000
589222
Bechtel S.,Rosenfelder H.,Duda A.,Schmidt C.P.,Ernst U.,Wellenreuther R.,Mehrle A.,Schuster C.,Bahr A.,Bloecker H.,Heubner D.,Hoerlein A.,Michel G.,Wedler H.,Koehrer K.,Ottenwaelder B.,Poustka A.,Wiemann S.,Schupp I.
The full-ORF clone resource of the German cDNA consortium.
BMC Genomics
8
399-399
2007
589223
Hillier L.W.,Graves T.A.,Fulton R.S.,Fulton L.A.,Pepin K.H.,Minx P.,Wagner-McPherson C.,Layman D.,Wylie K.,Sekhon M.,Becker M.C.,Fewell G.A.,Delehaunty K.D.,Miner T.L.,Nash W.E.,Kremitzki C.,Oddy L.,Du H.,Sun H.,Bradshaw-Cordum H.,Ali J.,Carter J.,Cordes M.,Harris A.,Isak A.,van Brunt A.,Nguyen C.,Du F.,Courtney L.,Kalicki J.,Ozersky P.,Abbott S.,Armstrong J.,Belter E.A.,Caruso L.,Cedroni M.,Cotton M.,Davidson T.,Desai A.,Elliott G.,Erb T.,Fronick C.,Gaige T.,Haakenson W.,Haglund K.,Holmes A.,Harkins R.,Kim K.,Kruchowski S.S.,Strong C.M.,Grewal N.,Goyea E.,Hou S.,Levy A.,Martinka S.,Mead K.,McLellan M.D.,Meyer R.,Randall-Maher J.,Tomlinson C.,Dauphin-Kohlberg S.,Kozlowicz-Reilly A.,Shah N.,Swearengen-Shahid S.,Snider J.,Strong J.T.,Thompson J.,Yoakum M.,Leonard S.,Pearman C.,Trani L.,Radionenko M.,Waligorski J.E.,Wang C.,Rock S.M.,Tin-Wollam A.-M.,Maupin R.,Latreille P.,Wendl M.C.,Yang S.-P.,Pohl C.,Wallis J.W.,Spieth J.,Bieri T.A.,Berkowicz N.,Nelson J.O.,Osborne J.,Ding L.,Meyer R.,Sabo A.,Shotland Y.,Sinha P.,Wohldmann P.E.,Cook L.L.,Hickenbotham M.T.,Eldred J.,Williams D.,Jones T.A.,She X.,Ciccarelli F.D.,Izaurralde E.,Taylor J.,Schmutz J.,Myers R.M.,Cox D.R.,Huang X.,McPherson J.D.,Mardis E.R.,Clifton S.W.,Warren W.C.,Chinwalla A.T.,Eddy S.R.,Marra M.A.,Ovcharenko I.,Furey T.S.,Miller W.,Eichler E.E.,Bork P.,Suyama M.,Torrents D.,Waterston R.H.,Wilson R.K.
Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
Nature
434
724-731
2005
589225
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
589226
Takeuchi T.,Kobayashi T.,Tamura S.,Yokosawa H.
Negative regulation of protein phosphatase 2Cbeta by ISG15 conjugation.
FEBS Lett.
580
4521-4526
2006
589227
Kaur R.,Yuan X.,Lu M.L.,Balk S.P.
Increased PAK6 expression in prostate cancer and identification of PAK6 associated proteins.
Prostate
68
1510-1516
2008
589228
Sun W.,Yu Y.,Dotti G.,Shen T.,Tan X.,Savoldo B.,Pass A.K.,Chu M.,Zhang D.,Lu X.,Fu S.,Lin X.,Yang J.
PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation.
Cell. Signal.
21
95-102
2009
589229
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
589230
Bruce D.L.,Macartney T.,Yong W.,Shou W.,Sapkota G.P.
Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-beta pathway.
Cell. Signal.
24
1999-2006
2012
589231
Zhao Y.,Liang L.,Fan Y.,Sun S.,An L.,Shi Z.,Cheng J.,Jia W.,Sun W.,Mori-Akiyama Y.,Zhang H.,Fu S.,Yang J.
PPM1B negatively regulates antiviral response via dephosphorylating TBK1.
Cell. Signal.
24
2197-2204
2012
589232
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
589233
Thinon E.,Serwa R.A.,Broncel M.,Brannigan J.A.,Brassat U.,Wright M.H.,Heal W.P.,Wilkinson A.J.,Mann D.J.,Tate E.W.
Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.
Nat. Commun.
5
4919-4919
2014
589234
Almo S.C.,Bonanno J.B.,Sauder J.M.,Emtage S.,Dilorenzo T.P.,Malashkevich V.,Wasserman S.R.,Swaminathan S.,Eswaramoorthy S.,Agarwal R.,Kumaran D.,Madegowda M.,Ragumani S.,Patskovsky Y.,Alvarado J.,Ramagopal U.A.,Faber-Barata J.,Chance M.R.,Sali A.,Fiser A.,Zhang Z.Y.,Lawrence D.S.,Burley S.K.
Structural genomics of protein phosphatases.
J. Struct. Funct. Genomics
8
121-140
2007