Sequence of MEP1B_RAT
EC Number:3.4.24.63
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Hydrolysis of proteins, including azocasein, and peptides. Hydrolysis of -His5-/-Leu-, -Leu6-/-Cys-, -Ala14-/-Leu- and -Cys19-/-Gly- bonds in insulin B chain
General information:
Sequence
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>P28826|meprin B|EC 3.4.24.63|Rattus norvegicus|Swiss-Prot
MDARHWPWFLVFATFLLVSGLPAPEKFVKDIDGGIDQDIFDINEDLGLDLFEGDIKLEAS
GRNSIIGDNYRWPHTIPYVLEDSLEMNAKGVILNAFERYRLKTCIDFKPWSGEENYISVF
KGSGCWSSVGNIHAGKQELSIGTNCDRIATVQHEFLHALGFWHEQSRADRDDYITIVWDR
ILSGKEHNFNIYNDSVSDSLNVPYDYTSVMHYSKTAFQNGTESTIITKISDFEDVIGQRM
DFSDYDLLKLNQLYSCTSSLSFMDSCDFELENICGMIQSSQDSADWQRLSQVLSGPENDH
SNMGQCKDSGFFMHFNTSTGNGGVTAMLESRVLYPKRGFQCVEFYLYNSGSGNGQLNVYT
REYTAGHQDGVLTLQREIRDIPTGSWQLYYVTLQVTEKFRVVFEGVGGPGASSGGLSIDD
INLSETRCPHHIWHIQNFTQLLGGQTTVYSPPFYSSKGYAFQINLDLTSPTNVGLYFHLI
SGANDDQLQWPCPWQQATMTLLDQNPDIRQRMSNQRSITTDPKMTDDNGSYLWDRPSKVG
VEAFFPNGTQFSRGRGYGTSVFITQERLKSREFLKGDDVYILLTVEDISHLNSTAAVPGP
VPTTSTVHNACSEVECQNGGICTLQEGRAECKCPAGEDWWYMGKRCEKRGSTKDTIVIAV
SSTVTVFAVMLIITLISVYCTRRKYRKKASAKTAAMNLENQHAF
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
487273
Johnson G.D.,Hersh L.B.
Cloning a rat meprin cDNA reveals the enzyme is a heterodimer.
J. Biol. Chem.
267
13505-13512
1992
487276
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
487277
Chevallier S.,Ahn J.,Boileau G.,Crine P.
Identification of the cysteine residues implicated in the formation of alpha 2 and alpha/beta dimers of rat meprin.
Biochem. J.
317
731-738
1996
487278
Ishmael F.T.,Shier V.K.,Ishmael S.S.,Bond J.S.
Intersubunit and domain interactions of the meprin B metalloproteinase. Disulfide bonds and protein-protein interactions in the MAM and TRAF domains.
J. Biol. Chem.
280
13895-13901
2005
