Sequence of INP51_YEAST
EC Number:3.1.3.36
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
phosphoinositide 5-phosphatase
P40559
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
946
108430
Reaction
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate
Other sequences found for EC No. 3.1.3.36
General information:
Sequence
0 MRLFIGRRSR SIVISSNNYC LSFQRLRSIP GASSQQRQLS KTPSVTIKSY PDTDLSSDSN
60 YLEVKSCIFN GLLGLVCLNG DIYVAVISGV QNVGFPRWKL IDHQVRPSES IYKVLDVDFY
120 SLENDVFDYL LCERSEQNYD KLIHEHPCGP LKKLFSDGTF YYSRDFDISN IVKNHGLSHN
180 LEYTVDNQDL SFIWNANLAS EVINWRSKIS NEEKQLFANA GFLTFVIRGY CKTALIEDGP
240 NTASITIISR ISTESKQDTL ELEGISEDGR VSLFVETEIV VTTEKFIFSY TQVNGSIPLF
300 WESVESQLLY GKKIKVTKDS IEAQGAFDRH FDNLTSKYGV VSIVNIIKPK SESQEKLALT
360 YKDCAESKGI KITNIEYSSS VLTKSPHKLL YLLKQDIYEF GAFAYDISRG IYFAKQTGVL
420 RISAFDSIEK PNTVERLVSK EVLELTTNEI DVFELTSPFL DAHDKLWSEN YYWLDRTYTK
480 HTKNSGKYTK VYSKLFGSRV RLYDPLHIYI SQYLKQLRSK YTFEKDISIF AGTFNISGKI
540 PKDDIKDWIF PKSMSKEDEM ADLYVIGLEE VVELTPGHML ATDPYVRQFW EKKILTLLNG
600 PGRKKKYIRL WSTQLGGILL LLFMNETEYS KVKHIEGDVK KTGFGGMASN KGAVAVSFKY
660 SATRFCVLVS HLAAGLENVE QRHNDYKTIA KSIRFSKGLR IKDHDAIIWM GDFNYRILMS
720 NEDVRRKIVS KEYASLFEKD QLNQQMIAGE SFPYFHEMAI DFPPTYKFDP GTKNYDTSEK
780 MRIPAWTDRI LSRGEVLEQL EYKCCEDILF SDHRPVYAIF RARVTVVDEQ KKTTLGTQIY
840 EKIMERLEGL DDDEKIAVLS DDAFVIESFE GSDSIAGPTH SPTPIPEPKR GRKLPPPSSD
900 LKKWWIGSGK QVKVVLDVDP AVYMINPKRD PNPFVENEDE PLFIER
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
558530
Voss H.,Tamames J.,Teodoru C.,Valencia A.,Sensen C.,Wiemann S.,Schwager C.,Zimmermann J.,Sander C.,Ansorge W.
Nucleotide sequence and analysis of the centromeric region of yeast chromosome IX.
Yeast
11
61-78
1995
558531
Churcher C.M.,Bowman S.,Badcock K.,Bankier A.T.,Brown D.,Chillingworth T.,Connor R.,Devlin K.,Gentles S.,Hamlin N.,Harris D.E.,Horsnell T.,Hunt S.,Jagels K.,Jones M.,Lye G.,Moule S.,Odell C.,Pearson D.,Rajandream M.A.,Rice P.,Rowley N.,Skelton J.,Smith V.,Walsh S.V.,Whitehead S.,Barrell B.G.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.
Nature
387
84-87
1997
558532
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
558533
Luo W.-J.,Chang A.
Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant.
J. Cell Biol.
138
731-746
1997
558534
Stolz L.E.,Huynh C.V.,Thorner J.,York J.D.
Identification and characterization of an essential family of inositol polyphosphate 5-phosphatases (INP51, INP52 and INP53 gene products) in the yeast Saccharomyces cerevisiae.
Genetics
148
1715-1729
1998
558535
Singer-Krueger B.,Nemoto Y.,Daniell L.,Ferro-Novick S.,De Camilli P.
Synaptojanin family members are implicated in endocytic membrane traffic in yeast.
J. Cell Sci.
111
3347-3356
1998
558536
O'Malley C.J.,McColl B.K.,Kong A.M.,Ellis S.L.,Wijayaratnam A.P.W.,Sambrook J.,Mitchell C.A.
Mammalian inositol polyphosphate 5-phosphatase II can compensate for the absence of all three yeast Sac1-like-domain-containing 5-phosphatases.
Biochem. J.
355
805-817
2001
558537
Huh W.-K.,Falvo J.V.,Gerke L.C.,Carroll A.S.,Howson R.W.,Weissman J.S.,O'Shea E.K.
Global analysis of protein localization in budding yeast.
Nature
425
686-691
2003
558538
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
558539
Morales-Johansson H.,Jenoe P.,Cooke F.T.,Hall M.N.
Negative regulation of phosphatidylinositol 4,5-bisphosphate levels by the INP51-associated proteins TAX4 and IRS4.
J. Biol. Chem.
279
39604-39610
2004
558540
Nguyen P.H.,Hasek J.,Kohlwein S.D.,Romero C.,Choi J.H.,Vancura A.
Interaction of Pik1p and Sjl proteins in membrane trafficking.
FEMS Yeast Res.
5
363-371
2005
558541
Fadri M.,Daquinag A.,Wang S.,Xue T.,Kunz J.
The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2.
Mol. Biol. Cell
16
1883-1900
2005
558542
Sun Y.,Carroll S.,Kaksonen M.,Toshima J.Y.,Drubin D.G.
PtdIns(4,5)P2 turnover is required for multiple stages during clathrin- and actin-dependent endocytic internalization.
J. Cell Biol.
177
355-367
2007
