Sequence of DNAS1_RAT
EC Number:3.1.21.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
endonucleolytic cleavage to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end-products
General information:
Sequence
0 MRYTGLMGIL LTLVNLLQLA ATLRIAAFNI RTFGDTKMSN ATLSSYIVKI LSRYDIAVVQ
60 EVRDTHLVAV GKLLDELNRD IPDNYRYIIS EPLGRKSYKE QYLFVYRPSQ VSVLDSYHYD
120 DGCEPCGNDT FSREPAIVKF FSPYTEVREF AIVPLHSAPT EAVSEIDALY DVYLDVRQKW
180 GLEDIMFMGD FNAGCSYVTS SQWSSIRLRT SPIFQWLIPD SADTTATSTH CAYDRIVVAG
240 ALLQAAVVPS SAVPFDFQAE YRLTNQMAEA ISDHYPVEVT LRKT
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
458741
Polzar B.,Mannherz H.G.
Nucleotide sequence of a full length cDNA clone encoding the deoxyribonuclease I from the rat parotid gland.
Nucleic Acids Res.
18
7151-7151
1990
458742
Liu Q.Y.,Ribecco M.,Hou Y.,Walker P.R.,Sikorska M.
DNase I primary transcript is alternatively spliced in both normal and apoptotic cells: no evidence of up-regulation in apoptosis.
DNA Cell Biol.
16
911-918
1997
458743
Basnakian A.G.,Singh A.B.,Shah S.V.
Identification and expression of deoxyribonuclease (DNase) I alternative transcripts in the rat.
Gene
289
87-96
2002
458744
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
458745
Peitsch M.C.,Polzar B.,Stephan H.,Crompton T.,McDonald H.R.,Mannherz H.G.,Tschopp J.
Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death).
EMBO J.
12
371-377
1993
458746
Napirei M.,Wulf S.,Eulitz D.,Mannherz H.G.,Kloeckl T.
Comparative characterization of rat deoxyribonuclease 1 (Dnase1) and murine deoxyribonuclease 1-like 3 (Dnase1l3).
Biochem. J.
389
355-364
2005
