Sequence of CATD_MOUSE
EC Number:3.4.23.5
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His bond in B chain of insulin
General information:
Sequence
0 MKTPGVLLLI LGLLASSSFA IIRIPLRKFT SIRRTMTEVG GSVEDLILKG PITKYSMQSS
60 PKTTEPVSEL LKNYLDAQYY GDIGIGTPPQ CFTVVFDTGS SNLWVPSIHC KILDIACWVH
120 HKYNSDKSST YVKNGTSFDI HYGSGSLSGY LSQDTVSVPC KSDQSKARGI KVEKQIFGEA
180 TKQPGIVFVA AKFDGILGMG YPHISVNNVL PVFDNLMQQK LVDKNIFSFY LNRDPEGQPG
240 GELMLGGTDS KYYHGELSYL NVTRKAYWQV HMDQLEVGNE LTLCKGGCEA IVDTGTSLLV
300 GPVEEVKELQ KAIGAVPLIQ GEYMIPCEKV SSLPTVYLKL GGKNYELHPD KYILKVSQGG
360 KTICLSGFMG MDIPPPSGPL WILGDVFIGS YYTVFDRDNN RVGFANAVVL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
445407
Diedrich J.F.,Staskus K.A.,Retzel E.F.,Haase A.T.
Nucleotide sequence of a cDNA encoding mouse cathepsin D.
Nucleic Acids Res.
18
7184-7184
1990
445408
Grusby M.J.,Mitchell S.C.,Glimcher L.H.
Molecular cloning of mouse cathepsin D.
Nucleic Acids Res.
18
4008-4008
1990
445409
Hetman M.,Perschl A.,Saftig P.,von Figura K.,Peters C.
Mouse cathepsin D gene: molecular organization, characterization of the promoter, and chromosomal localization.
DNA Cell Biol.
13
419-427
1994
445410
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
445411
Uematsu R.,Furukawa J.,Nakagawa H.,Shinohara Y.,Deguchi K.,Monde K.,Nishimura S.
High throughput quantitative glycomics and glycoform-focused proteomics of murine dermis and epidermis.
Mol. Cell. Proteomics
4
1977-1989
2005
445412
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
445413
Beel S.,Moisse M.,Damme M.,De Muynck L.,Robberecht W.,Van Den Bosch L.,Saftig P.,Van Damme P.
Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo.
Hum. Mol. Genet.
26
2850-2863
2017
