Sequence of AOXA_HUMAN

aldehyde oxidase

Q06278

1338

147918

4904

Wright R.M.,Vaitaitis G.M.,Wilson C.M.,Repine T.B.,Terada L.S.,Repine J.E.

cDNA cloning, characterization, and tissue-specific expression of human xanthine dehydrogenase/xanthine oxidase.

Proc. Natl. Acad. Sci. U.S.A.

90

10690-10694

1993

4906

Ichida K.,Matsumura T.,Sakuma R.,Hosoya T.,Nishino T.

Mutation of human molybdenum cofactor sulfurase gene is responsible to classical xanthinuria type II.

Biochem. Biophys. Res. Commun.

282

1194-1200

2001

4907

Hillier L.W.,Graves T.A.,Fulton R.S.,Fulton L.A.,Pepin K.H.,Minx P.,Wagner-McPherson C.,Layman D.,Wylie K.,Sekhon M.,Becker M.C.,Fewell G.A.,Delehaunty K.D.,Miner T.L.,Nash W.E.,Kremitzki C.,Oddy L.,Du H.,Sun H.,Bradshaw-Cordum H.,Ali J.,Carter J.,Cordes M.,Harris A.,Isak A.,van Brunt A.,Nguyen C.,Du F.,Courtney L.,Kalicki J.,Ozersky P.,Abbott S.,Armstrong J.,Belter E.A.,Caruso L.,Cedroni M.,Cotton M.,Davidson T.,Desai A.,Elliott G.,Erb T.,Fronick C.,Gaige T.,Haakenson W.,Haglund K.,Holmes A.,Harkins R.,Kim K.,Kruchowski S.S.,Strong C.M.,Grewal N.,Goyea E.,Hou S.,Levy A.,Martinka S.,Mead K.,McLellan M.D.,Meyer R.,Randall-Maher J.,Tomlinson C.,Dauphin-Kohlberg S.,Kozlowicz-Reilly A.,Shah N.,Swearengen-Shahid S.,Snider J.,Strong J.T.,Thompson J.,Yoakum M.,Leonard S.,Pearman C.,Trani L.,Radionenko M.,Waligorski J.E.,Wang C.,Rock S.M.,Tin-Wollam A.-M.,Maupin R.,Latreille P.,Wendl M.C.,Yang S.-P.,Pohl C.,Wallis J.W.,Spieth J.,Bieri T.A.,Berkowicz N.,Nelson J.O.,Osborne J.,Ding L.,Meyer R.,Sabo A.,Shotland Y.,Sinha P.,Wohldmann P.E.,Cook L.L.,Hickenbotham M.T.,Eldred J.,Williams D.,Jones T.A.,She X.,Ciccarelli F.D.,Izaurralde E.,Taylor J.,Schmutz J.,Myers R.M.,Cox D.R.,Huang X.,McPherson J.D.,Mardis E.R.,Clifton S.W.,Warren W.C.,Chinwalla A.T.,Eddy S.R.,Marra M.A.,Ovcharenko I.,Furey T.S.,Miller W.,Eichler E.E.,Bork P.,Suyama M.,Torrents D.,Waterston R.H.,Wilson R.K.

Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

Nature

434

724-731

2005

4909

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

4910

Beedham C.,Critchley D.J.,Rance D.J.

Substrate specificity of human liver aldehyde oxidase toward substituted quinazolines and phthalazines: a comparison with hepatic enzyme from guinea pig, rabbit, and baboon.

Arch. Biochem. Biophys.

319

481-490

1995

4911

Rashidi M.R.,Smith J.A.,Clarke S.E.,Beedham C.

In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liver.

Drug Metab. Dispos.

25

805-813

1997

4912

Neumeier M.,Weigert J.,Schaeffler A.,Weiss T.S.,Schmidl C.,Buettner R.,Bollheimer C.,Aslanidis C.,Schoelmerich J.,Buechler C.

Aldehyde oxidase 1 is highly abundant in hepatic steatosis and is down-regulated by adiponectin and fenofibric acid in hepatocytes in vitro.

Biochem. Biophys. Res. Commun.

350

731-735

2006

4913

Garattini E.,Fratelli M.,Terao M.

Mammalian aldehyde oxidases: genetics, evolution and biochemistry.

Cell. Mol. Life Sci.

65

1019-1048

2008

4914

Weigert J.,Neumeier M.,Bauer S.,Mages W.,Schnitzbauer A.A.,Obed A.,Groeschl B.,Hartmann A.,Schaeffler A.,Aslanidis C.,Schoelmerich J.,Buechler C.

Small-interference RNA-mediated knock-down of aldehyde oxidase 1 in 3T3-L1 cells impairs adipogenesis and adiponectin release.

FEBS Lett.

582

2965-2972

2008

4915

Zientek M.,Jiang Y.,Youdim K.,Obach R.S.

In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase.

Drug Metab. Dispos.

38

1322-1327

2010

4916

Hutzler J.M.,Yang Y.S.,Albaugh D.,Fullenwider C.L.,Schmenk J.,Fisher M.B.

Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes.

Drug Metab. Dispos.

40

267-275

2012

4917

Strelevitz T.J.,Orozco C.C.,Obach R.S.

Hydralazine as a selective probe inactivator of aldehyde oxidase in human hepatocytes: estimation of the contribution of aldehyde oxidase to metabolic clearance.

Drug Metab. Dispos.

40

1441-1448

2012

4918

Garattini E.,Terao M.

The role of aldehyde oxidase in drug metabolism.

Expert Opin. Drug Metab. Toxicol.

8

487-503

2012

4919

Barr J.T.,Jones J.P.

Evidence for substrate-dependent inhibition profiles for human liver aldehyde oxidase.

Drug Metab. Dispos.

41

24-29

2013

4920

Fu C.,Di L.,Han X.,Soderstrom C.,Snyder M.,Troutman M.D.,Obach R.S.,Zhang H.

Aldehyde oxidase 1 (AOX1) in human liver cytosols: quantitative characterization of AOX1 expression level and activity relationship.

Drug Metab. Dispos.

41

1797-1804

2013

4921

Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

J. Proteomics

96

253-262

2014

4922

Coelho C.,Foti A.,Hartmann T.,Santos-Silva T.,Leimkuhler S.,Romao M.J.

Structural insights into xenobiotic and inhibitor binding to human aldehyde oxidase.

Nat. Chem. Biol.

11

779-783

2015

4923

Foti A.,Hartmann T.,Coelho C.,Santos-Silva T.,Romao M.J.,Leimkuhler S.

Optimization of the Expression of Human Aldehyde Oxidase for Investigations of Single-Nucleotide Polymorphisms.

Drug Metab. Dispos.

44

1277-1285

2016

4924

Hartmann T.,Terao M.,Garattini E.,Teutloff C.,Alfaro J.F.,Jones J.P.,Leimkuehler S.

The impact of single nucleotide polymorphisms on human aldehyde oxidase.

Drug Metab. Dispos.

40

856-864

2012